Deciphering the different phases of preclinical inflammatory bowel disease

Xavier, R. J. & Podolsky, D. K. Unravelling the pathogenesis of inflammatory bowel disease. Nature 448, 427–434 (2007).

Article  CAS  PubMed  Google Scholar 

Torres, J. et al. Crohn’s disease. Lancet 389, 1741–1755 (2017).

Article  PubMed  Google Scholar 

Ungaro, R. C. et al. Ulcerative colitis. Lancet 289, 1756–1770 (2017).

Article  Google Scholar 

Chang, J. T. Pathophysiology of inflammatory bowel diseases. N. Engl. J. Med. 383, 2652–2664 (2020).

Article  CAS  PubMed  Google Scholar 

Ng, S. C. et al. Worldwide incidence and prevalence of inflammatory bowel disease in the 21st century: a systematic review of population-based studies. Lancet 390, 2769–2778 (2017).

Article  PubMed  Google Scholar 

Frazzei, G. et al. Preclinical autoimmune disease: a comparison of rheumatoid arthritis, systemic lupus erythematosus, multiple sclerosis and type 1 diabetes. Front. Immunol. 13, 899372 (2022).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Greenblatt, K. H. et al. Preclinical rheumatoid arthritis and rheumatoid arthritis prevention. Curr. Opin. Rheumatol. 32, 289–296 (2020).

Article  PubMed  PubMed Central  Google Scholar 

Robertson, J. M. & James, J. A. Preclinical systemic lupus erythematosus. Rheum. Dis. Clin. North Am. 40, 621–635 (2014).

Article  PubMed  PubMed Central  Google Scholar 

Israeli, E. et al. Anti-Saccharomyces cerevisiae and antineutrophil cytoplasmic antibodies as predictors of inflammatory bowel disease. Gut 54, 1232–1236 (2005).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Torres, J. et al. Results of the Seventh Scientific Workshop of ECCO: Precision Medicine in IBD — Prediction and Prevention of Inflammatory Bowel Disease. J. Crohns Colitis 15, 1443–1454 (2021).

Article  PubMed  Google Scholar 

De Lange, K. M. et al. Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease. Nat. Genet. 49, 256–261 (2017).

Article  PubMed  PubMed Central  Google Scholar 

Graham, D. B. & Xavier, R. J. Pathway paradigms revealed from the genetics of inflammatory bowel disease. Nature 578, 527–539 (2020).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Agrawal, M. et al. Early life exposures and the risk of inflammatory bowel disease: systematic review and meta-analyses. EClinicalMedicine 36, 100884 (2021). Comprehensive systemic review and meta-analysis collecting the available knowledge of early life risk factors and showing the importance of the early life period in the risk of later IBD development.

Article  PubMed  PubMed Central  Google Scholar 

Piovani, D. et al. Environmental risk factors for inflammatory bowel diseases: an umbrella review of meta-analyses. Gastroenterology 157, 647–659.e4 (2019).

Article  PubMed  Google Scholar 

Halme, L. et al. Family and twin studies in inflammatory bowel disease. World J. Gastroenterol. 12, 3668–3672 (2006).

Article  PubMed  PubMed Central  Google Scholar 

Jess, T. et al. Disease concordance, zygosity, and NOD2/CARD15 status: follow-up of a population-based cohort of Danish twins with inflammatory bowel disease. Am. J. Gastroenterol. 100, 2486–2492 (2005).

Article  CAS  PubMed  Google Scholar 

Orholm, M. et al. Familial occurrence of inflammatory bowel disease. N. Engl. J. Med. 324, 84–88 (1991).

Article  CAS  PubMed  Google Scholar 

Liu, J. Z. et al. Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations. Nat. Genet. 47, 979–986 (2015). Large trans-ancestry study that not just discovers new genetic risk loci, but also shows that some genetic heterogeneity is present between divergent populations in some of the risk loci.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Van Limbergen, J. et al. Advances in IBD genetics. Nat. Rev. Gastroenterol. Hepatol. 11, 372–385 (2014).

Article  PubMed  Google Scholar 

Barker, D. J. P. The origins of the developmental origins theory. J. Intern. Med. 261, 412–417 (2007).

Article  CAS  PubMed  Google Scholar 

Colebatch, A. N. & Edwards, C. J. The influence of early life factors on the risk of developing rheumatoid arthritis. Clin. Exp. Immunol. 163, 11–16 (2011).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Haupt-Jørgensen, M. et al. Maternal antibiotic use during pregnancy and type 1 diabetes in children – a national prospective cohort study. Diabetes Care 41, e155–e157 (2018).

Article  PubMed  Google Scholar 

Al Nabhani, Z. & Eberl, G. Imprinting of the immune system by the microbiota early in life. Mucosal Immunol. 13, 183–189 (2020).

Article  CAS  PubMed  Google Scholar 

Agrawal, M. et al. Early-life mebendazole exposure increases the risk of adult-onset ulcerative colitis: a population-based cohort study. Am. J. Gastroenterol. 117, 2025–2032 (2022).

Article  CAS  PubMed  Google Scholar 

Agrawal, M. et al. Maternal antibiotic exposure during pregnancy and risk of IBD in offspring: a population-based cohort study. Gut 72, 804–805 (2023).

Article  PubMed  Google Scholar 

Elten, M. et al. Ambient air pollution and the risk of pediatric-onset inflammatory bowel disease: a population-based cohort study. Environ. Int. 138, 105676 (2020).

Article  CAS  PubMed  Google Scholar 

Elten, M. et al. Residential greenspace in childhood reduces risk of pediatric inflammatory bowel disease: a population-based cohort study. Am. J. Gastroenterol. 116, 347–353 (2021).

Article  PubMed  Google Scholar 

Lee, S. H. et al. Peri-natal exposure to parental Crohn’s disease is associated with impaired gut barrier, microbiome composition differences and increased risk of Crohn’s disease [abstract OP29]. J. Crohns Colitis 17 (Suppl. 1), i40–i47 (2023).

Google Scholar 

Nair, N. et al. Association between early-life exposures and inflammatory bowel diseases, based on analyses of deciduous teeth. Gastroenterology 159, 383–385 (2020). An interesting study showing the usefulness of an unconventional sample type (deciduous teeth) to investigate environmental exposures and risk of IBD.

Article  PubMed  Google Scholar 

Torres, J. et al. Infants born to mothers with IBD present with altered gut microbiome that transfers abnormalities of the adaptive immune system to germ-free mice. Gut 69, 42–51 (2020).

Article  CAS  PubMed  Google Scholar 

Kim, E. S. et al. Longitudinal changes in fecal calprotectin levels among pregnant women with and without inflammatory bowel disease and their babies. Gastroenterology 160, 1118–1130.e3 (2021).

Article  CAS  PubMed  Google Scholar 

Soon, I. S. et al. The relationship between urban environment and inflammatory bowel disease: a systematic review and meta-analysis [abstract 1265]. Am. J. Gastroenterol. 105, S465 (2010).

Article  Google Scholar 

Lo, C. H. et al. Ultra-processed foods and risk of Crohn’s disease and ulcerative colitis: a prospective cohort study. Clin. Gastroenterol. Hepatol. 20, e1323–e1337 (2022).

Article  CAS  PubMed  Google Scholar 

Narula, N. et al. Association of ultra-processed food intake with risk of inflammatory bowel disease: prospective cohort study. BMJ 374, n1554 (2021).

Article  PubMed  PubMed Central  Google Scholar 

Chen, J. et al. Intake of ultra-processed foods is associated with an increased risk of Crohn’s disease: a cross-sectional and prospective analysis of 187 154 participants in the UK Biobank. J. Crohns Colitis 17, 535–552 (2022).

Article  PubMed Central  Google Scholar 

Axelrad, J. E. et al. Systematic review: gastrointestinal infection and incident inflammatory bowel disease. Aliment. Pharmacol. Ther. 51, 1222–1232 (2020).

Article  PubMed  PubMed Central  Google Scholar 

Cosnes, J. et al. Gender differences in the response of colitis to smoking. Clin. Gastroenterol. Hepatol. 2, 41–48 (2004).

Article  PubMed  Google Scholar 

Karczewski, J. et al. The effect of cigarette smoking on the clinical course of inflammatory bowel disease. Prz. Gastroenterol. 9, 153–159 (2014).

PubMed  PubMed Central  Google Scholar 

Mahid, S. S. et al. Smoking and inflammatory bowel disease: a meta-analysis. Mayo Clin. Proc. 81, 1462–1471 (2006).

Article  PubMed  Google Scholar 

Torres, J. et al. Risk factors for developing inflammatory bowel disease within and across families with a family history of IBD. J. Crohns Colitis 17, 30–36 (2023).

Article 

留言 (0)

沒有登入
gif