Nandaa RS. The contributions of craniofacial growth to clinical orthodontics. Am J Orthod Dentofac Orthop. 2000;117:553–5.

Article  Google Scholar 

Rebouças PRM, Alencar CRB, Arruda MJA, et al. Identification of dental calcification stages as a predictor of skeletal development phase. Dent Press J Orthod. 2021;26:e2119292.

Article  Google Scholar 

Cameron N, Schell L, editors. Human growth and development. 3rd ed. Cambridge, MA: Academic Press; 2021.

Google Scholar 

Bogin B, editor. Patterns of human growth. Vol 88. 2nd ed. Cambridge: Cambridge University Press; 2020.

Google Scholar 

Walker SP, Wachs TD, Gardner JM, et al. Child development: risk factors for adverse outcomes in developing countries. The lancet. 2007;369:145–57.

Article  Google Scholar 

Cameron N. The measurement of human growth. In: Cameron N, Schell L, editors. Human growth and development. 3rd ed. Cambridge, MA: Academic Press; 2021. pp. 317–45.

Google Scholar 

Cobourne MT. The genetic control of early odontogenesis. Br J Orthod. 1999;26:21–8.

Article  CAS  PubMed  Google Scholar 

Demirjian A, Goldstein H, Tanner JM. A new system of dental age assessment. Hum Biol. 1973;211–27.

Surendran S, Thomas E. Tooth mineralization stages as a diagnostic tool for assessment of skeletal maturity. Am J Orthod Dentofac Orthop. 2014;145:7–14.

Article  Google Scholar 

Cericato GO, Bittencourt MAV, Paranhos LR. Validity of the assessment method of skeletal maturation by cervical vertebrae: a systematic review and meta-analysis. Dentomaxillofacial Radiol. 2015;44:20140270.

Article  CAS  Google Scholar 

Santiago RC, de Miranda Costa LF, Vitral RWF, Fraga MR, Bolognese AM, Maia LC. Cervical vertebral maturation as a biologic indicator of skeletal maturity: a systematic review. Angle Orthod. 2012;82:1123–31.

Article  PubMed  PubMed Central  Google Scholar 

Rim EY, Clevers H, Nusse R. The wnt pathway: from signaling mechanisms to synthetic modulators. Annu Rev Biochem. 2022;91:571–98.

Article  PubMed  Google Scholar 

Ackers I, Malgor R. Interrelationship of canonical and non-canonical wnt signalling pathways in chronic metabolic diseases. Diabetes and Vascular Disease Research. 2018;15:3–13.

Article  CAS  PubMed  Google Scholar 

Nemoto E, Sakisaka Y, Tsuchiya M, et al. Wnt3a signaling induces murine dental follicle cells to differentiate into cementoblastic/osteoblastic cells via an osterix-dependent pathway. J Periodontal Res. 2016;51:164–74.

Article  CAS  PubMed  Google Scholar 

Koizumi Y, Kawashima N, Yamamoto M, et al. Wnt11 expression in rat dental pulp and promotional effects of W nt signaling on odontoblast differentiation. Congenit Anom. 2013;53:101–8.

Article  CAS  Google Scholar 

Liu S, Zhang E, Yang M, Lu L. Overexpression of Wnt11 promotes chondrogenic differentiation of bone marrow-derived mesenchymal stem cells in synergism with TGF-β. Mol Cell Biochem. 2014;390:123–31.

Article  CAS  PubMed  Google Scholar 

Zhu JH, Liao YP, Li FS, et al. Wnt11 promotes BMP9-induced osteogenic differentiation through BMPs/Smads and p38 MAPK in mesenchymal stem cells. J Cell Biochem. 2018;119:9462–73.

Article  CAS  PubMed  Google Scholar 

Xu ML, Bi CWC, Liu EYL, Dong TTX, Tsim KWK. Wnt3a induces the expression of acetylcholinesterase during osteoblast differentiation via the Runx2 transcription factor. J Biol Chem. 2017;292:12667–78.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Camilleri S, McDonald F. Runx2 and dental development. Eur J Oral Sci. 2006;114:361–73.

Article  CAS  PubMed  Google Scholar 

Komori T. Signaling networks in RUNX2-dependent bone development. J Cell Biochem. 2011;112:750–5.

Article  CAS  PubMed  Google Scholar 

Gaur T, Lengner CJ, Hovhannisyan H, et al. Canonical WNT signaling promotes osteogenesis by directly stimulating Runx2 gene expression. J Biol Chem. 2005;280:33132–40.

Article  CAS  PubMed  Google Scholar 

Han N, Zheng Y, Li R, et al. β-catenin enhances odontoblastic differentiation of dental pulp cells through activation of Runx2. PLoS ONE. 2014;9:e88890.

Article  PubMed  PubMed Central  Google Scholar 

Nicholas CL, Kadavy K, Holton NE, Marshall T, Richter A, Southard T. Childhood body mass index is associated with early dental development and eruption in a longitudinal sample from the Iowa Facial Growth Study. Am J Orthod Dentofac Orthop. 2018;154:72–81.

Article  Google Scholar 

Sadeghianrizi A, Forsberg C-M, Marcus C, Dahllöf G. Craniofacial development in obese adolescents. Eur J Orthod. 2005;27:550–5.

Article  PubMed  Google Scholar 

Modesto A, Jacas CA, Kim SM, et al. Childhood obesity, genetic variation, and dental age. Pediatr Dent. 2019;41:132–5.

PubMed  Google Scholar 

Vallejo-Bolaños E, España‐López AJ, Muñoz‐Hoyos A, Fernandez‐Garcia JM. The relationship between bone age, chronological age and dental age in children with isolated growth hormone deficiency. Int J Pediatr Dent. 1999;9:201–6.

Article  Google Scholar 

Kjellberg H, Beiring M, Wikland KA. Craniofacial morphology, dental occlusion, tooth eruption, and dental maturity in boys of short stature with or without growth hormone deficiency. Eur J Oral Sci. 2000;108:359–67.

Article  CAS  PubMed  Google Scholar 

Küchler EC, Reis CLB, Carelli J, et al. Potential interactions among single nucleotide polymorphisms in bone-and cartilage‐related genes in skeletal malocclusions. Orthod Craniofac Res. 2021;24:277–87.

Article  PubMed  Google Scholar 

Küchler EC, Reis CLB, Silva-Sousa AC, et al. Exploring the association between genetic polymorphisms in genes involved in craniofacial development and isolated tooth agenesis. Front Physiol. 2021;12:723105.

Article  PubMed  PubMed Central  Google Scholar 

Little J, Higgins JPT, Ioannidis JPA, et al. STrengthening the REporting of genetic Association Studies (STREGA)—an extension of the STROBE statement. Genetic epidemiology. The Official Publication of the International Genetic Epidemiology Society. 2009;33:581–98.

Article  Google Scholar 

Costacurta M, Sicuro L, Di Renzo L, Condò R, De Lorenzo A, Docimo R. Childhood obesity and skeletal-dental maturity. Eur J Pediatr Dentistry. 2012;13:128–32.

CAS  Google Scholar 

Hilgers KK, Akridge M, Scheetz JP, Kinane DF. Childhood obesity and dental development. Pediatr Dent. 2006;28:18–22.

PubMed  Google Scholar 

Baccetti T, Franchi L, McNamara JA Jr. The cervical vertebral maturation (CVM) method for the assessment of optimal treatment timing in dentofacial orthopedics. Semin Orthod. 2005;11:119–29.

Article  Google Scholar 

Schoretsaniti L, Mitsea A, Karayianni K, Sifakakis I. Cervical vertebral maturation method: reproducibility and efficiency of chronological age estimation. Appl Sci. 2021;11:3160.

Article  CAS  Google Scholar 

Küchler EC, Tannure PN, Falagan-Lotsch P, Lopes TS, Granjeiro JM, Amorim LMF. Buccal cells DNA extraction to obtain high quality human genomic DNA suitable for polymorphism genotyping by PCR-RFLP and real-time PCR. J Appl Oral Sci. 2012;20:467–71.

Article  PubMed  PubMed Central  Google Scholar 

de Freitas EM, Machado RA, de Moura Santos E, et al. Polymorphisms associated with oral clefts as potential susceptibility markers for oral and breast cancer. Arch Oral Biol. 2019;99:9–14.

Article  PubMed  Google Scholar 

Esan TA, Schepartz LA. Accuracy of the Demirjian and Willems methods of age estimation in a black southern african population. Leg Med. 2018;31:82–9.

Article  Google Scholar 

Reis CLB, Barbosa MCF, Henklein S, et al. Nutritional status is associated with permanent tooth eruption in a group of brazilian school children. Global Pediatr Health. 2021;8:2333794X211034088.

Article  Google Scholar 

Küchler EC, Reis CLB, Marañón-Vásquez G, et al. Parathyroid hormone gene and genes involved in the maintenance of vitamin D levels association with mandibular retrognathism. J Personalized Med. 2021;11:369.

Article  Google Scholar 

Eid RMR, Simi R, Friggi MNP, Fisberg M. Assessment of dental maturity of brazilian children aged 6 to 14 years using Demirjian’s method. Int J Pediatr Dent. 2002;12:423–8.

Article  CAS  Google Scholar 

Jayaraman J, Wong HM, King NM, Roberts GJ. The french–canadian data set of Demirjian for dental age estimation: a systematic review and meta-analysis. J Forensic Leg Med. 2013;20:373–81.

Article  PubMed  Google Scholar 

Silvério KG, Davidson KC, James RG, et al. Wnt/β-catenin pathway regulates bone morphogenetic protein (BMP2)‐mediated differentiation of dental follicle cells. J Periodontal Res. 2012;47:309–19.

Article  PubMed  Google Scholar 

Xiang L, Chen M, He L, et al. Wnt5a regulates dental follicle stem/progenitor cells of the periodontium. Stem Cell Res Ther. 2014;5:1–9.

Article  Google Scholar 

Menezes R, Letra A, Kim AH, et al. Studies with wnt genes and nonsyndromic cleft lip and palate. Birth defects Research Part A. Clin Mol Teratology. 2010;88:995–1000.

Article  CAS  Google Scholar 

Riethoven J-JM. Regulatory regions in DNA: promoters, enhancers, silencers, and insulators. Comput biology transcription factor binding. 2010;674:33–42.

Article  CAS