Al-Aly Z, Xie Y, Bowe B. High-dimensional characterization of post-acute sequelae of COVID-19. Nature. 2021;594:259–64. https://doi.org/10.1038/s41586-021-03553-9.

Article  CAS  PubMed  Google Scholar 

Alnefeesi Y, Siegel A, Lui LMW, et al. Impact of SARS-CoV-2 infection on cognitive function: a systematic review. Front Psychiatry. 2021. https://doi.org/10.3389/fpsyt.2020.621773.

Article  PubMed  PubMed Central  Google Scholar 

Batmyagmar D, Kundi M, Ponocny-Seliger E, et al. High intensity endurance training is associated with better quality of life, but not with improved cognitive functions in elderly marathon runners. Sci Rep. 2019. https://doi.org/10.1038/s41598-019-41010-w.

Article  PubMed  PubMed Central  Google Scholar 

Becker JH, Lin JJ, Doernberg M, et al. Assessment of cognitive function in patients after COVID-19 infection. JAMA Netw Open. 2021. https://doi.org/10.1001/jamanetworkopen.2021.30645.

Article  PubMed  PubMed Central  Google Scholar 

Benedini S, Dozio E, Invernizzi PL, et al. Irisin: a potential link between physical exercise and metabolism - an observational study in differently trained subjects, from elite athletes to sedentary people. J Diabetes Res. 2017. https://doi.org/10.1155/2017/1039161.

Article  PubMed  PubMed Central  Google Scholar 

Besedovsky L, Lange T, Haack M. The sleep-immune crosstalk in health and disease. Physiol Rev. 2019;99:1325–80. https://doi.org/10.1152/physrev.

Article  PubMed  PubMed Central  Google Scholar 

Boidin M, Handfield N, Ribeiro PAB, et al. Obese but fit: the benefits of fitness on cognition in obese older adults. Can J Cardiol. 2020. https://doi.org/10.1016/j.cjca.2020.01.005.

Article  PubMed  Google Scholar 

Boström P, Wu J, Jedrychowski MP, et al. A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis. Nature. 2012;481:463–8. https://doi.org/10.1038/nature10777.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Businaro P, Vaghi G, Marchioni E, et al. COVID-19 in patients with myasthenia gravis: epidemiology and disease course. Muscle Nerve. 2021;64:206–11. https://doi.org/10.1002/mus.27324.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Caria ACI, Nonaka CKV, Pereira CS, et al. Exercise training-induced changes in microRNAs: beneficial regulatory effects in hypertension, type 2 diabetes, and obesity. Int J Mol Sci. 2018;19:3608.

Article  Google Scholar 

Cassilhas RC, De Sousa RAL, Caxa L, et al. Indoor aerobic exercise reduces exposure to pollution, improves cognitive function, and enhances BDNF levels in the elderly. Air Qual Atmos Heal. 2022;15:35–45. https://doi.org/10.1007/s11869-021-01083-x.

Article  CAS  Google Scholar 

Cassilhas RC, Lee KS, Fernandes J, et al. Spatial memory is improved by aerobic and resistance exercise through divergent molecular mechanisms. Neuroscience. 2012;202:309–17. https://doi.org/10.1016/j.neuroscience.2011.11.029.

Article  CAS  PubMed  Google Scholar 

Cavalcante BRR, Improta-Caria AC, de Melo VH, De Sousa RAL. Exercise-linked consequences on epilepsy. Epilepsy Behav. 2021;121:108079.

Article  PubMed  Google Scholar 

Chang SL, Harding N, Zachreson C, et al. Modelling transmission and control of the COVID-19 pandemic in Australia. Nat Commun. 2020. https://doi.org/10.1038/s41467-020-19393-6.

Article  PubMed  PubMed Central  Google Scholar 

Chou SHY, Beghi E, Helbok R, et al. Global incidence of neurological manifestations among patients hospitalized with COVID-19—a report for the GCS-NeuroCOVID consortium and the ENERGY consortium. JAMA Netw Open. 2021. https://doi.org/10.1001/jamanetworkopen.2021.12131.

Article  PubMed  PubMed Central  Google Scholar 

Clement-Carbonell V, Portilla-Tamarit I, Rubio-Aparicio M, Madrid-Valero JJ. Sleep quality, mental and physical health: a differential relationship. Int J Environ Res Public Health. 2021;18:1–8. https://doi.org/10.3390/ijerph18020460.

Article  Google Scholar 

da Silveira MP, da Silva Fagundes KK, Bizuti MR, et al. Physical exercise as a tool to help the immune system against COVID-19: an integrative review of the current literature. Clin Exp Med. 2021;21:15–28.

Article  PubMed  Google Scholar 

Davis BE, Lakin L, Binns CC, et al. Patient and provider insights into the impact of multiple sclerosis on mental health: a narrative review. Neurol Ther. 2021;10:99–119.

Article  PubMed  PubMed Central  Google Scholar 

de Lima NS, De Sousa RAL, Amorim FT, et al. Moderate-intensity continuous training and high-intensity interval training improve cognition, and BDNF levels of middle-aged overweight men. Metab Brain Dis. 2022;37:463–71. https://doi.org/10.1007/s11011-021-00859-5.

Article  CAS  PubMed  Google Scholar 

De Melo VH, De Sousa RAL, Improta-Caria AC, Nunes MAP. Physical activity and quality of life in adults and elderly individuals with lower limb amputation. Rev Assoc Med Bras. 2021;67:985–90. https://doi.org/10.1590/1806-9282.20210382.

Article  PubMed  Google Scholar 

de Oliveira LRS, Machado FSM, Rocha-Dias I, et al. An overview of the molecular and physiological antidepressant mechanisms of physical exercise in animal models of depression. Mol Biol Rep. 2022;49:4965–75. https://doi.org/10.1007/s11033-022-07156-z.

Article  CAS  PubMed  Google Scholar 

de Oliveira M, De Sibio MT, Mathias LS, et al. Irisin modulates genes associated with severe coronavirus disease (COVID-19) outcome in human subcutaneous adipocytes cell culture. Mol Cell Endocrinol. 2020. https://doi.org/10.1016/j.mce.2020.110917.

Article  PubMed  PubMed Central  Google Scholar 

De Sousa RAL. Reactive gliosis in Alzheimer’s disease: a crucial role for cognitive impairment and memory loss. Metab Brain Dis. 2022;37:851–7. https://doi.org/10.1007/s11011-022-00953-2.

Article  CAS  PubMed  Google Scholar 

De Sousa RAL. Gestational diabetes is associated to the development of brain insulin resistance in the offspring. Int J Diabetes Dev Ctries. 2019;39:408–16.

Article  Google Scholar 

De Sousa RAL. Brief report of the effects of the aerobic, resistance, and high-intensity interval training in type 2 diabetes mellitus individuals. Int J Diabetes Dev Ctries. 2018;38:138–45.

Article  Google Scholar 

De Sousa RAL, Improta-Caria AC, Aras-Júnior R, et al. Physical exercise effects on the brain during COVID-19 pandemic: links between mental and cardiovascular health. Neurol Sci. 2021;42:1325–34.

Article  PubMed  PubMed Central  Google Scholar 

De Sousa RAL, Improta-Caria AC, Cassilhas RC. Effects of physical exercise on memory in type 2 diabetes: a brief review. Metab Brain Dis. 2021;36:1559–63.

Article  PubMed  Google Scholar 

De Sousa RAL, Improta-Caria AC, de Jesus-Silva FM, et al. High-intensity resistance training induces changes in cognitive function, but not in locomotor activity or anxious behavior in rats induced to type 2 diabetes. Physiol Behav. 2020. https://doi.org/10.1016/j.physbeh.2020.112998.

Article  PubMed  Google Scholar 

De Sousa RAL, Improta-Caria AC, de Souza BS, F,. Exercise-linked irisin: consequences on mental and cardiovascular health in type 2 diabetes. Int J Mol Sci. 2021;22:1–15.

Article  Google Scholar 

De Sousa RAL, Mendes BF, Costa-Pereira L, et al. Accumulated high-intensity interval training protocol: a new approach to study health markers in wistar rats. J Vis Exp. 2022. https://doi.org/10.3791/63328.

Article  PubMed  Google Scholar 

De Sousa RAL, Peixoto MFD, Leite HR, et al. Neurological consequences of exercise during prenatal Zika virus exposure to mice pups. Int J Neurosci. 2020. https://doi.org/10.1080/00207454.2020.1860970.

Article  PubMed  Google Scholar 

De Sousa RAL, Rocha-Dias I, de Oliveira LRS, et al. Molecular mechanisms of physical exercise on depression in the elderly: a systematic review. Mol Biol Rep. 2021;48:3853–62. https://doi.org/10.1007/s11033-021-06330-z.

Article  CAS  PubMed  Google Scholar 

De Sousa RAL, Santos LG, Lopes PM, et al. Physical exercise consequences on memory in obesity: a systematic review. Obes Rev. 2021. https://doi.org/10.1111/obr.13298.

Article  PubMed  Google Scholar 

Deng J, Zhou F, Hou W, et al. The prevalence of depression, anxiety, and sleep disturbances in COVID-19 patients: a meta-analysis. Ann NY Acad Sci. 2021;1486:90–111. https://doi.org/10.1111/nyas.14506.

Article  CAS  PubMed  Google Scholar 

Liegro Di, Schiera P, Liegro Di. Physical activity and brain health. Genes. 2019;10:720. https://doi.org/10.3390/genes10090720.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Di Stefano V, Ornello R, Gagliardo A, et al. Social distancing in chronic migraine during the covid-19 outbreak: results from a multicenter observational study. Nutrients. 2021. https://doi.org/10.3390/nu13041361.

Article  PubMed  PubMed Central  Google Scholar 

Dinel AL, André C, Aubert A, et al. Cognitive and emotional alterations are related to hippocampal inflammation in a mouse model of metabolic syndrome. PLoS ONE. 2011. https://doi.org/10.1371/journal.pone.0024325.

Article  PubMed  PubMed Central  Google Scholar 

Douaud G, Lee S, Alfaro-Almagro F, et al. SARS-CoV-2 is associated with changes in brain structure in UK biobank. Nature. 2022;604:697–707. https://doi.org/10.1038/s41586-022-04569-5.

Article  CAS