An Extract of Taro (Colocasia esculenta) Mediates Potent Inhibitory Actions on Metastatic and Cancer Stem Cells by Tumor Cell-Autonomous and Immune-Dependent Mechanisms

1. Brown, AC, Ibrahim, SA, Song, D. Poi history, uses, and role in health. In: Watson, RR, Preedy, V, eds. Fruits, Vegetables, and Herbs: Bioactive Foods in Health Promotion. Oxford, UK: Academic Press; 2016:331-342.
Google Scholar2. Brown, AC, Reitzenstein, JE, Liu, J, Jadus, MR. The anti-cancer effects of poi (Colocasia esculenta) on colonic adenocarcinoma cells in vitro. Phytother Res. 2005;19:767-771.
Google Scholar | Crossref | Medline3. Kundu, N, Campbell, P, Hampton, B, et al. Antimetastatic activity isolated from Colocasia esculenta (taro). Anticancer Drugs. 2012;23:200-211.
Google Scholar | Crossref | Medline4. Pereira, PR, Silva, JT, Verícimo, MA, Paschoalin, VMF, Teixeira, GAPB. Crude extract from taro (Colocasia esculenta) as a natural source of bioactive proteins able to stimulate haematopoietic cells in two murine models. J Funct Foods. 2015;18:333-343.
Google Scholar | Crossref5. Pereira, PR, Correa, A, Vericimo, MA, Paschoalin, VMF. Tarin, a potential immunomodulator and COX-inhibitor lectin found in taro (Colocasia esculenta). Compr Rev Food Sci Food Saf. 2018;17:878-891.
Google Scholar | Crossref | Medline6. Pereira, PR, Del Aguila, EM, Vericimo, MA, Zingali, RB, Paschoalin, VM, Silva, JT. Purification and characterization of the lectin from taro (Colocasia esculenta) and its effect on mouse splenocyte proliferation in vitro and in vivo. Protein J. 2014;33:92-99.
Google Scholar | Crossref | Medline7. Park, HR, Lee, HS, Cho, SY, Kim, YS, Shin, KS. Anti-metastatic effect of polysaccharide isolated from Colocasia esculenta is exerted through immunostimulation. Int J Mol Med. 2013;31:361-368.
Google Scholar | Crossref | Medline8. Merida, LAD, Mattos, EBA, Correa, A, et al. Tarin stimulates granulocyte growth in bone marrow cell cultures and minimizes immunosuppression by cyclophosphamide in mice. PLoS ONE. 2018;12:e0206240.
Google Scholar9. Kundu, N, Ma, X, Kochel, T, et al. Prostaglandin E receptor EP4 is a therapeutic target in breast cancer cells with stem-like properties. Breast Cancer Res Treat. 2014;143:19-31.
Google Scholar | Crossref | Medline10. Lin, L, Hutzen, B, Lee, HF, et al. Evaluation of STAT3 signaling in ALDH+ and ALDH+/CD44+/CD24- subpopulations of breast cancer cells. PLoS ONE. 2013;8:e82821.
Google Scholar | Crossref | Medline11. Correa, A, Vericimo, MA, Dashevskiy, A, Pereira, PR, Paschoalin, VMF. Liposomal taro lectin nanocapsules control human glioblastoma and mammary adenocarcinoma cell proliferation. Molecules. 2019;24:471.
Google Scholar | Crossref12. Pereira, PR, Winter, HC, Vericimo, MA, et al. Structural analysis and binding properties of isoforms of tarin, the GNA-related lectin from Colocasia esculenta. Biochim Biophys Acta. 2015;1854:20-30.
Google Scholar | Crossref | Medline13. Pereira, PR, Meagher, JL, Winter, HC, et al. High-resolution crystal structures of Colocasia esculenta tarin lectin. Glycobiology. 2017;27:50-56.
Google Scholar | Crossref | Medline14. Zhao, R, Liu, X, Wang, Y, et al. Integrated glycomic analysis of ovarian cancer side population cells. Clin Proteomics. 2016;13:32.
Google Scholar | Crossref | Medline15. Mallard, BW, Tiralongo, J. Cancer stem cell marker glycosylation: nature, function and significance. Glycoconj J. 2017;34:441-452.
Google Scholar | Crossref | Medline16. Barkeer, S, Chugh, S, Batra, SK, Ponnusamy, MP. Glycosylation of cancer stem cells: function in stemness, tumorigenesis and metastasis. Neoplasia. 2018;20:813-825.
Google Scholar | Crossref | Medline17. Vajravijayan, S, Pletnev, S, Pletnev, VZ, Nandhagopal, N, Gunasekaran, K. Structural analysis of β-prism lectin from Colocasia esculenta (L.) S chott. Int J Biol Macromol. 2016;91:518-523.
Google Scholar | Crossref | Medline

留言 (0)

沒有登入
gif