Hu FB, Manson JE, Stampfer MJ, Colditz G, Liu S, Solomon CG, et al. Diet, lifestyle, and the risk of type 2 diabetes mellitus in women. N Engl J Med. 2001;345(11):790–7.
Bi Y, Wang T, Xu M, Xu Y, Li M, Lu J, et al. Advanced research on risk factors of type 2 diabetes. Diab Metabol Res Rev. 2012;28:32–9.
Chen L, Pei J-H, Kuang J, Chen H-M, Chen Z, Li Z-W, et al. Effect of lifestyle intervention in patients with type 2 diabetes: a meta-analysis. Metabolism. 2015;64(2):338–47.
Ogurtsova K, da Rocha FJ, Huang Y, Linnenkamp U, Guariguata L, Cho NH, et al. IDF diabetes atlas: global estimates for the prevalence of diabetes for 2015 and 2040. Diab Res Clin Pract. 2017;128:40–50.
Jafari-Adli S, Jouyandeh Z, Qorbani M, Soroush A, Larijani B, Hasani-Ranjbar S. Prevalence of obesity and overweight in adults and children in Iran; a systematic review. J Diab Metabol Dis. 2014;13(1):1–10.
Rabe K, Lehrke M, Parhofer KG, Broedl UC. Adipokines and insulin resistance. Mol Med. 2008;14:741–51.
CAS PubMed PubMed Central Google Scholar
Berg AH, Combs TP, Scherer PE. ACRP30/adiponectin: an adipokine regulating glucose and lipid metabolism. Trends Endocrinol Metabol. 2002;13(2):84–9.
Ouchi N, Parker JL, Lugus JJ, Walsh K. Adipokines in inflammation and metabolic disease. Nat Rev Immunol. 2011;11(2):85–97.
CAS PubMed PubMed Central Google Scholar
Gettins PG. Serpin structure, mechanism, and function. Chem Rev. 2002;102(12):4751–804.
Law RH, Zhang Q, McGowan S, Buckle AM, Silverman GA, Wong W, et al. An overview of the serpin superfamily. Genome Biol. 2006;7:1–11.
Blüher M. Vaspin in obesity and diabetes: pathophysiological and clinical significance. Endocrine. 2012;41(2):176–82.
Klöting N, Berndt J, Kralisch S, Kovacs P, Fasshauer M, Schön MR, et al. Vaspin gene expression in human adipose tissue: association with obesity and type 2 diabetes. Biochem Biophys Res Commun. 2006;339(1):430–6.
Cash JL, Hart R, Russ A, Dixon JP, Colledge WH, Doran J, et al. Synthetic chemerin-derived peptides suppress inflammation through ChemR23. J Exp Med. 2008;205(4):767–75.
CAS PubMed PubMed Central Google Scholar
Goralski KB, McCarthy TC, Hanniman EA, Zabel BA, Butcher EC, Parlee SD, et al. Chemerin, a novel adipokine that regulates adipogenesis and adipocyte metabolism. J Biol Chem. 2007;282(38):28175–88.
Tan L, Lu X, Danser AJ, Verdonk K. The role of chemerin in metabolic and cardiovascular disease: a literature review of its physiology and pathology from a nutritional perspective. Nutrients. 2023;15(13):2878.
CAS PubMed PubMed Central Google Scholar
Najafi Z, Feizi MAH, Abbasaliizadeh S. Haplotype effect of two human leukocyte antigen-G polymorphisms of rs1736933 and rs2735022 on the recurrent pregnancy loss. J Inflamm Dis. 2021;24(5):398–409.
Hashemi M, Rezaei H, Eskandari-Nasab E, Zakeri Z, Taheri M. Association between chemerin rs17173608 and vaspin rs2236242 gene polymorphisms and the metabolic syndrome, a preliminary report. Gene. 2012;510(2):113–7.
Mehanna ET, Mesbah NM, Ghattas MH, Saleh SM, Abo-Elmatty DM. Association of chemerin Rs17173608 and vaspin Rs2236242 gene polymorphisms with metabolic syndrome in Egyptian women. Endocr Res. 2016;41(1):43–8.
Kwok S, Kellogg D, McKinney N, Spasic D, Goda L, Levenson C, et al. Effects of primer-template mismatches on the polymerase chain reaction: human immunodeficiency virus type 1 model studies. Nucl Acids Res. 1990;18(4):999–1005.
CAS PubMed PubMed Central Google Scholar
Anscombe FJ. On estimating binomial response relations. Biometrika. 1956;43(3/4):461–4.
Haldane J. The mean and variance of| chi 2, when used as a test of homogeneity, when expectations are small. Biometrika. 1940;31(3/4):346–55.
Mambiya M, Shang M, Wang Y, Li Q, Liu S, Yang L, et al. The play of genes and non-genetic factors on type 2 diabetes. Front Public Health. 2019;7:349.
PubMed PubMed Central Google Scholar
Wang CH, Wang CC, Huang HC, Wei YH. Mitochondrial dysfunction leads to impairment of insulin sensitivity and adiponectin secretion in adipocytes. FEBS J. 2013;280(4):1039–50.
Abdelhamid AM, Zaafan MA. Association of chemerin rs17173608 and vaspin rs2236242 polymorphisms with type two diabetes mellitus and its impact on their corresponding serum levels in Egyptian population. 2019. ideas.
Rathwa N, Parmar N, Palit SP, Patel R, Ramachandran A, Begum R. Intron specific polymorphic site of vaspin gene along with vaspin circulatory levels can influence pathophysiology of type 2 diabetes. Life Sci. 2020;243: 117285.
Hosseini M, Nezhadali M, Hedayati M. Association of vaspin rs2236242 gene polymorphism with serum vaspin level, insulin resistance and diabetes in an Iranian diabetic/pre-diabetic population. J Med Biochem. 2021;40(1):33.
CAS PubMed PubMed Central Google Scholar
Ghany SMA, Sayed AA, El-Deek SE, ElBadre HM, Dahpy MA, Saleh MA, et al. Obesity risk prediction among women of Upper Egypt: The impact of serum vaspin and vaspin rs2236242 gene polymorphism. Gene. 2017;626:140–8.
Jian W, Peng W, Xiao S, Li H, Jin J, Qin L, et al. Role of serum vaspin in progression of type 2 diabetes: a 2-year cohort study. PLoS ONE. 2014;9(4): e94763.
PubMed PubMed Central Google Scholar
Dai RongFeng DR, Dong ZhenHua DZ, Qian Yu QY, Han Yan HY. Obese type 2 diabetes mellitus patients have higher serum vaspin concentrations. 2016.
Yang W, Li Y, Tian T, Wang L. Serum vaspin concentration in elderly type 2 diabetes mellitus patients with differing body mass index: a cross-sectional study. BioMed Res Int. 2017;2017(1):4875026.
PubMed PubMed Central Google Scholar
Breitfeld J, Wiele N, Gutsmann B, Stumvoll M, Blüher M, Scholz M, et al. Circulating adipokine VASPIN is associated with serum lipid profiles in humans. Lipids. 2019;54(4):203–10.
Bozaoglu K, Bolton K, McMillan J, Zimmet P, Jowett J, Collier G, et al. Chemerin is a novel adipokine associated with obesity and metabolic syndrome. Endocrinology. 2007;148(10):4687–94.
Yang M, Yang G, Dong J, Liu Y, Zong H, Liu H, et al. Elevated plasma levels of chemerin in newly diagnosed type 2 diabetes mellitus with hypertension. J Invest Med. 2010;58(7):883–6.
Sell H, Divoux A, Poitou C, Basdevant A, Bouillot J-L, Bedossa P, et al. Chemerin correlates with markers for fatty liver in morbidly obese patients and strongly decreases after weight loss induced by bariatric surgery. J Clin Endocrinol Metabol. 2010;95(6):2892–6.
Weigert J, Neumeier M, Wanninger J, Filarsky M, Bauer S, Wiest R, et al. Systemic chemerin is related to inflammation rather than obesity in type 2 diabetes. Clin Endocrinol. 2010;72(3):342–8.
Millar DS, Horan M, Chuzhanova NA, Cooper DN. Characterisation of a functional intronic polymorphism in the human growth hormone (GHI) gene. Human Genom. 2010;4:1–13.
Hasanvand Z, Sadeghi A, Rezvanfar MR, Goodarzi MT, Rahmannezhad G, Mashayekhi FJ. Association between chemerin rs17173608 and rs4721 gene polymorphisms and gestational diabetes mellitus in Iranian pregnant women. Gene. 2018;649:87–92.
Becker M, Rabe K, Lebherz C, Zugwurst J, Göke B, Parhofer KG, et al. Expression of human chemerin induces insulin resistance in the skeletal muscle but does not affect weight, lipid levels, and atherosclerosis in LDL receptor knockout mice on high-fat diet. Diabetes. 2010;59(11):2898–903.
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