How Fear Memory is Updated: From Reconsolidation to Extinction?

Koenen KC, Ratanatharathorn A, Ng L, McLaughlin KA, Bromet EJ, Stein DJ. Posttraumatic stress disorder in the world mental health surveys. Psychol Med 2017, 47: 2260–2274.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Xiao W, Liu X, Wang H, Huang Y, Dai Z, Si M, et al. Prevalence and risk for symptoms of PTSD among survivors of a COVID-19 infection. Psychiatry Res 2023, 326: 115304.

Article  PubMed  PubMed Central  Google Scholar 

Girgenti MJ, Wang J, Ji D, Cruz DA, Stein MB, et al. Transcriptomic organization of the human brain in post-traumatic stress disorder. Nat Neurosci 2021, 24: 24–33.

Article  CAS  PubMed  Google Scholar 

Chamaa F, Bahmad HF, Darwish B, Kobeissi JM, Hoballah M, Nassif SB, et al. PTSD in the COVID-19 era. Curr Neuropharmacol 2021, 19: 2164–2179.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Yuan K, Gong YM, Liu L, Sun YK, Tian SS, Wang YJ, et al. Prevalence of posttraumatic stress disorder after infectious disease pandemics in the twenty-first century, including COVID-19: A meta-analysis and systematic review. Mol Psychiatry 2021, 26: 4982–4998.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bao Y, Sun Y, Meng S, Shi J, Lu L. 2019-nCoV epidemic: Address mental health care to empower society. Lancet 2020, 395: e37–e38.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Khanna A, Jones GB. Envisioning post-pandemic digital neurological, psychiatric and mental health care. Front Digit Health 2021, 3: 803315.

Article  PubMed  PubMed Central  Google Scholar 

Guideline Development Panel for the Treatment of Ptsd in Adults AcPA. Summary of the clinical practice guideline for the treatment of posttraumatic stress disorder (PTSD) in adults. Am Psychol 2019, 74: 596–607.

van Gelderen MJ, Nijdam MJ, Haagen JFG, Vermetten E. Interactive motion-assisted exposure therapy for veterans with treatment-resistant posttraumatic stress disorder: A randomized controlled trial. Psychother Psychosom 2020, 89: 215–227.

Article  PubMed  Google Scholar 

Post RM, Kegan R. Prevention of recurrent affective episodes using extinction training in the reconsolidation window: A testable psychotherapeutic strategy. Psychiatry Res 2017, 249: 327–336.

Article  PubMed  Google Scholar 

Rothbaum BO, McSweeney LB. Patients need to remain in treatment for PTSD to receive the full benefit. J Anxiety Disord 2019, 68: 102156.

Article  PubMed  Google Scholar 

Wells SY, Morland LA, Hurst S, Jackson GL, Kehle-Forbes SM, Jaime K, et al. Veterans’ reasons for dropping out of prolonged exposure therapy across three delivery modalities: A qualitative examination. Psychol Serv 2023, 20: 483–495.

Article  PubMed  Google Scholar 

Brooks SK, Greenberg N. Recurrence of post-traumatic stress disorder: Systematic review of definitions, prevalence and predictors. BMC Psychiatry 2024, 24: 37.

Article  PubMed  PubMed Central  Google Scholar 

Okano H, Hirano T, Balaban E. Learning and memory. Proc Natl Acad Sci U S A 2000, 97: 12403–12404.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zlotnik G, Vansintjan A. Memory: An extended definition. Front Psychol 2019, 10: 2523.

Article  PubMed  PubMed Central  Google Scholar 

Squire L, Kandel E. Memory: From mind to molecules. Nat Med, 2003

Müller GE, Pilzecker A. Experimentelle Beiträge Zur Lehre Vom Gedächtniss [German]. 1 ed: J. A. Barth, Leipzig, 1900.

Nader K, Schafe GE, Le Doux JE. Fear memories require protein synthesis in the amygdala for reconsolidation after retrieval. Nature 2000, 406: 722–726.

Article  CAS  PubMed  Google Scholar 

Frankland PW, Bontempi B. The organization of recent and remote memories. Nat Rev Neurosci 2005, 6: 119–130.

Article  CAS  PubMed  Google Scholar 

Misanin JR, Miller RR, Lewis DJ. Retrograde Amnesia produced by electroconvulsive shock after reactivation of a consolidated memory trace. Science 1968, 160: 554–555.

Article  CAS  PubMed  Google Scholar 

Schneider AM, Sherman W. Amnesia: A function of the temporal relation of footshock to electroconvulsive shock. Science 1968, 159: 219–221.

Article  CAS  PubMed  Google Scholar 

Lewis DJ. Sources of experimental Amnesia. Psychol Rev 1969, 76: 461–472.

Article  CAS  PubMed  Google Scholar 

Alberini CM, LeDoux JE. Memory reconsolidation. Curr Biol 2013, 23: R746–R750.

Article  CAS  PubMed  Google Scholar 

Bouton ME. Context, time, and memory retrieval in the interference paradigms of Pavlovian learning. Psychol Bull 1993, 114: 80–99.

Article  CAS  PubMed  Google Scholar 

Eisenberg M, Kobilo T, Berman DE, Dudai Y. Stability of retrieved memory: Inverse correlation with trace dominance. Science 2003, 301: 1102–1104.

Article  CAS  PubMed  Google Scholar 

Lu Y, Sun XD, Hou FQ, Bi LL, Yin DM, Liu F, et al. Maintenance of GABAergic activity by neuregulin 1-ErbB4 in amygdala for fear memory. Neuron 2014, 84: 835–846.

Article  CAS  PubMed  Google Scholar 

Kintscher M, Kochubey O, Schneggenburger R. A striatal circuit balances learned fear in the presence and absence of sensory cues. Elife 2023, 12: e75703.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Tovote P, Fadok JP, Lüthi A. Neuronal circuits for fear and anxiety. Nat Rev Neurosci 2015, 16: 317–331.

Article  CAS  PubMed  Google Scholar 

Pedraza LK, Sierra RO, de Oliveira Alvares L. Systems consolidation and fear memory generalisation as a potential target for trauma-related disorders. World J Biol Psychiatry 2022, 23: 653–665.

Article  PubMed  Google Scholar 

Yehuda R, Hoge CW, McFarlane AC, Vermetten E, Lanius RA, Nievergelt CM, et al. Post-traumatic stress disorder. Nat Rev Dis Primers 2015, 1: 15057.

Article  PubMed  Google Scholar 

Phelps EA, Hofmann SG. Memory editing from science fiction to clinical practice. Nature 2019, 572: 43–50.

Article  CAS  PubMed  Google Scholar 

Monfils MH, Cowansage KK, Klann E, LeDoux JE. Extinction-reconsolidation boundaries: Key to persistent attenuation of fear memories. Science 2009, 324: 951–955.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Schiller D, Monfils MH, Raio CM, Johnson DC, Ledoux JE, Phelps EA. Preventing the return of fear in humans using reconsolidation update mechanisms. Nature 2010, 463: 49–53.

Article  CAS  PubMed  Google Scholar 

Gräff J, Joseph NF, Horn ME, Samiei A, Meng J, Seo J, et al. Epigenetic priming of memory updating during reconsolidation to attenuate remote fear memories. Cell 2014, 156: 261–276.

Article  PubMed  PubMed Central  Google Scholar 

Comments (0)

No login
gif