Adler S, Olsen W, Rackerby B, Spencer R, Dallas DC (2023) Effects of whey protein supplementation on inflammatory marker concentrations in older adults. Nutrients 15(18):4081

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ahmadi A, Eftekhari MH, Mazloom Z, Masoompour M, Fararooei M, Eskandari MH et al (2020) Fortified whey beverage for improving muscle mass in chronic obstructive pulmonary disease: a single-blind, randomized clinical trial. Respir Res 21:1–11

Article  Google Scholar 

Anthony JC, Anthony TG, Kimball SR, Jefferson LS (2001) Signaling pathways involved in translational control of protein synthesis in skeletal muscle by leucine. J Nutr 131(3):856S-S860

Article  CAS  PubMed  Google Scholar 

Antunes I, Bexiga R, Pinto C, Roseiro L, Quaresma M (2022) Cow’s milk in human nutrition and the emergence of plant-based milk alternatives. Foods 12(1):99

Article  PubMed  PubMed Central  Google Scholar 

Begg CB, Berlin JA (1988) Publication bias: a problem in interpreting medical data. J R Stat Soc A Stat Soc 151(3):419–445

Article  Google Scholar 

Bhowmik R, Shaharyar MA, Sarkar A, De A, Mandal A, Shabana H et al (2023) Role of natural products in inflammatory pharmacology: harnessing nature’s potential through drug delivery for therapeutic intervention. J Chem Health Risks. https://doi.org/10.53555/jchr.v13.i4s.759

Article  Google Scholar 

Biesek S, Vojciechowski AS, Filho JM, Menezes Ferreira ACRd, Borba VZC, Rabito EI et al (2021) Effects of exergames and protein supplementation on body composition and musculoskeletal function of prefrail community-dwelling older women: a randomized, controlled clinical trial. Int J Environ Res Public Health 18(17):9324

Article  CAS  PubMed  PubMed Central  Google Scholar 

Björkman M, Finne-Soveri H, Tilvis R (2012) Whey protein supplementation in nursing home residents. A randomized controlled trial. Eur Geriatr Med 3(3):161–166

Article  Google Scholar 

Bohl M, Bjørnshave A, Gregersen S, Hermansen K (2016) Whey and casein proteins and medium-chain saturated fatty acids from milk do not increase low-grade inflammation in abdominally obese adults. Rev Diabet Stud: RDS 13(2–3):148

Article  PubMed  PubMed Central  Google Scholar 

Borenstein M, Hedges LV, Higgins JP, Rothstein HR (2021) Introduction to meta-analysis. Wiley, NY

Book  Google Scholar 

Brimelow RE, West NP, Williams LT, Cripps AW, Cox AJ (2017) A role for whey-derived lactoferrin and immunoglobulins in the attenuation of obesity-related inflammation and disease. Crit Rev Food Sci Nutr 57(8):1593–1602

Article  CAS  PubMed  Google Scholar 

Bumrungpert A, Pavadhgul P, Nunthanawanich P, Sirikanchanarod A, Adulbhan A (2018) Whey protein supplementation improves nutritional status, glutathione levels, and immune function in cancer patients: a randomized, double-blind controlled trial. J Med Food 21(6):612–616

Article  CAS  PubMed  Google Scholar 

Chandran D, Lejaniya A, Mahesh S, Maneesh S, Sureshkumar R, Buttar HS et al (2021) Major health effects of casein and whey proteins present in cow milk: a narrative review. Indian Vet J 98(9):19

Google Scholar 

Chen L, Deng H, Cui H, Fang J, Zuo Z, Deng J et al (2018) Inflammatory responses and inflammation-associated diseases in organs. Oncotarget 9(6):7204

Article  PubMed  Google Scholar 

Claessens M, Van Baak M, Monsheimer S, Saris W (2009) The effect of a low-fat, high-protein or high-carbohydrate ad libitum diet on weight loss maintenance and metabolic risk factors. Int J Obes 33(3):296–304

Article  CAS  Google Scholar 

Corrochano AR, Buckin V, Kelly PM, Giblin L (2018) Invited review: Whey proteins as antioxidants and promoters of cellular antioxidant pathways. J Dairy Sci 101(6):4747–4761

Article  CAS  PubMed  Google Scholar 

Daenzer M, Petzke KJ, Metges CC, Bequette BJ (2001) Whole-body nitrogen and splanchnic amino acid metabolism differ in rats fed mixed diets containing casein or its corresponding amino acid mixture. J Nutr 131(7):1965–1972

Article  CAS  PubMed  Google Scholar 

Davoodi SH, Shahbazi R, Esmaeili S, Sohrabvandi S, Mortazavian A, Jazayeri S et al (2016) Health-related aspects of milk proteins. Iran J Pharm Res 15(3):573

CAS  PubMed  PubMed Central  Google Scholar 

Derosa G, D’Angelo A, Maffioli P (2020) Change of some oxidative stress parameters after supplementation with whey protein isolate in patients with type 2 diabetes. Nutrition 73:110700

Article  CAS  PubMed  Google Scholar 

DerSimonian R, Laird N (1986) Meta-analysis in clinical trials. Control Clin Trials. https://doi.org/10.1016/0197-2456(86)90046-2

Article  PubMed  Google Scholar 

Duff WR, Chilibeck PD, Rooke JJ, Kaviani M, Krentz JR, Haines DM (2014) The effect of bovine colostrum supplementation in older adults during resistance training. Int J Sport Nutr Exerc Metab 24(3):276–285

Article  CAS  PubMed  Google Scholar 

Dulac M, Pion C, Lemieux F, Carvalho LP, Boutros GEH, Bélanger M et al (2021) Effects of slow-v. fast-digested protein supplementation combined with mixed power training on muscle function and functional capacities in older men. Br J Nutr 125(9):1017–33

Article  CAS  PubMed  Google Scholar 

Ebaid H, Ahmed OM, Mahmoud AM, Ahmed RR (2013) Limiting prolonged inflammation during proliferation and remodeling phases of wound healing in streptozotocin-induced diabetic rats supplemented with camel undenatured whey protein. BMC Immunol 14:1–13

Article  Google Scholar 

Egger M, Smith GD, Schneider M, Minder C (1997) Bias in meta-analysis detected by a simple, graphical test. BMJ 315(7109):629–634

Article  CAS  PubMed  PubMed Central  Google Scholar 

Elahikhah M, Haidari F, Khalesi S, Shahbazian H, Mohammadshahi M, Aghamohammadi V (2024) Milk protein concentrate supplementation improved appetite, metabolic parameters, adipocytokines, and body composition in dieting women with obesity: a randomized controlled trial. BMC Nutr 10(1):80

Article  PubMed  PubMed Central  Google Scholar 

Fekete ÁA, Giromini C, Chatzidiakou Y, Givens DI, Lovegrove JA (2016) Whey protein lowers blood pressure and improves endothelial function and lipid biomarkers in adults with prehypertension and mild hypertension: results from the chronic Whey2Go randomized controlled trial. Am J Clin Nutr 104(6):1534–1544

Article  CAS  PubMed  PubMed Central  Google Scholar 

Fernandes RR, Nabuco HC, Junior PS, Cavalcante EF, Fabro PM, Tomeleri CM et al (2018) Effect of protein intake beyond habitual intakes following resistance training on cardiometabolic risk disease parameters in pre-conditioned older women. Exp Gerontol 110:9–14

Article  CAS  PubMed  Google Scholar 

Giglio BM, Schincaglia RM, da Silva AS, Fazani IC, Monteiro PA, Mota JF et al (2019) Whey protein supplementation compared to collagen increases blood Nesfatin concentrations and decreases android fat in overweight women: a randomized double-blind study. Nutrients 11(9):2051

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gjevestad GO, Ottestad I, Biong AS, Iversen PO, Retterstøl K, Raastad T et al (2017) Consumption of protein-enriched milk has minor effects on inflammation in older adults—a 12-week double-blind randomized controlled trial. Mech Ageing Dev 162:1–8

Article  CAS  PubMed  Google Scholar 

Gouni-Berthold I, Schulte DM, Krone W, Lapointe J-F, Lemieux P, Predel H-G et al (2012) The whey fermentation product malleable protein matrix decreases TAG concentrations in patients with the metabolic syndrome: a randomised placebo-controlled trial. Br J Nutr 107(11):1694–1706

Article  CAS  PubMed  Google Scholar 

Griffen C, Cullen T, Hattersley J, Weickert MO, Dallaway A, Duncan M et al (2024) Effects of resistance exercise and whey protein supplementation on cognitive function in older men: secondary analysis of a randomised, double-blind, placebo-controlled trial. Exp Gerontol 193:112477

Article  CAS  PubMed  Google Scholar 

Gryson C, Ratel S, Rance M, Penando S, Bonhomme C, Le Ruyet P et al (2014) Four-month course of soluble milk proteins interacts with exercise to improve muscle strength and delay fatigue in elderly participants. J Am Med Dir Assoc 15(12):958. e1-e9

Article  PubMed