C. Frick, H. Rumgay, J. Vignat, O. Ginsburg, E. Nolte, F. Bray, I. Soerjomataram, Quantitative estimates of preventable and treatable deaths from 36 cancers worldwide: a population-based study, Lancet Glob Health 11(11) (2023) e1700-e1712.
Article PubMed PubMed Central Google Scholar
H. Sung, J. Ferlay, R.L. Siegel, M. Laversanne, I. Soerjomataram, A. Jemal, F. Bray, Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries, CA Cancer J Clin 71(3) (2021) 209–249.
E. Morgan, M. Arnold, A. Gini, V. Lorenzoni, C.J. Cabasag, M. Laversanne, J. Vignat, J. Ferlay, N. Murphy, F. Bray, Global burden of colorectal cancer in 2020 and 2040: incidence and mortality estimates from GLOBOCAN, Gut 72(2) (2023) 338–344.
I. Ilic, M. Ilic, International patterns in incidence and mortality trends of pancreatic cancer in the last three decades: A joinpoint regression analysis, World J Gastroenterol 28(32) (2022) 4698–4715.
Article PubMed PubMed Central Google Scholar
National Cancer Institute, Cancer Stat Facts: Colorectal Cancer, 2024. https://seer.cancer.gov/statfacts/html/colorect.html. (Accessed 27. January 2024).
National Cancer Institute, Cancer Stat Facts: Pancreatic Cancer, 2024. https://seer.cancer.gov/statfacts/html/pancreas.html. (Accessed 27. January 2024).
H. Wang, J. Liu, G. Xia, S. Lei, X. Huang, X. Huang, Survival of pancreatic cancer patients is negatively correlated with age at diagnosis: a population-based retrospective study, Sci Rep 10(1) (2020) 7048.
Article CAS PubMed PubMed Central Google Scholar
D.I. Tsilimigras, P. Brodt, P.A. Clavien, R.J. Muschel, M.I. D’Angelica, I. Endo, R.W. Parks, M. Doyle, E. de Santibañes, T.M. Pawlik, Liver metastases, Nat Rev Dis Primers 7(1) (2021) 27.
F.A. Khan, R. Albalawi, F.H. Pottoo, Trends in targeted delivery of nanomaterials in colon cancer diagnosis and treatment, Med Res Rev 42(1) (2022) 227–258.
Article CAS PubMed Google Scholar
M.H. Sherman, G.L. Beatty, Tumor Microenvironment in Pancreatic Cancer Pathogenesis and Therapeutic Resistance, Annu Rev Pathol 18 (2023) 123–148.
Article CAS PubMed Google Scholar
S. Bärthel, C. Falcomatà, R. Rad, F.J. Theis, D. Saur, Single-cell profiling to explore pancreatic cancer heterogeneity, plasticity and response to therapy, Nat Cancer 4(4) (2023) 454–467.
Article PubMed PubMed Central Google Scholar
J. Peng, B.F. Sun, C.Y. Chen, J.Y. Zhou, Y.S. Chen, H. Chen, L. Liu, D. Huang, J. Jiang, G.S. Cui, Y. Yang, W. Wang, D. Guo, M. Dai, J. Guo, T. Zhang, Q. Liao, Y. Liu, Y.L. Zhao, D.L. Han, Y. Zhao, Y.G. Yang, W. Wu, Single-cell RNA-seq highlights intra-tumoral heterogeneity and malignant progression in pancreatic ductal adenocarcinoma, Cell Res 29(9) (2019) 725–738.
Article CAS PubMed PubMed Central Google Scholar
M. Gerlinger, A.J. Rowan, S. Horswell, M. Math, J. Larkin, D. Endesfelder, E. Gronroos, P. Martinez, N. Matthews, A. Stewart, P. Tarpey, I. Varela, B. Phillimore, S. Begum, N.Q. McDonald, A. Butler, D. Jones, K. Raine, C. Latimer, C.R. Santos, M. Nohadani, A.C. Eklund, B. Spencer-Dene, G. Clark, L. Pickering, G. Stamp, M. Gore, Z. Szallasi, J. Downward, P.A. Futreal, C. Swanton, Intratumor heterogeneity and branched evolution revealed by multiregion sequencing, N Engl J Med 366(10) (2012) 883–892.
Article CAS PubMed PubMed Central Google Scholar
I.J. Fidler, Biological heterogeneity of cancer: implication to therapy, Hum Vaccin Immunother 8(8) (2012) 1141–2.
Article CAS PubMed PubMed Central Google Scholar
I. Dagogo-Jack, A.T. Shaw, Tumour heterogeneity and resistance to cancer therapies, Nat Rev Clin Oncol 15(2) (2018) 81–94.
Article CAS PubMed Google Scholar
B. Ganeshan, K.A. Miles, Quantifying tumour heterogeneity with CT, Cancer Imaging 13(1) (2013) 140–9.
Article PubMed PubMed Central Google Scholar
F. Wang, J. Long, L. Li, Z.X. Wu, T.T. Da, X.Q. Wang, C. Huang, Y.H. Jiang, X.Q. Yao, H.Q. Ma, Z.X. Lian, Z.B. Zhao, J. Cao, Single-cell and spatial transcriptome analysis reveals the cellular heterogeneity of liver metastatic colorectal cancer, Sci Adv 9(24) (2023) eadf5464.
Article CAS PubMed PubMed Central Google Scholar
F. Davnall, C.S. Yip, G. Ljungqvist, M. Selmi, F. Ng, B. Sanghera, B. Ganeshan, K.A. Miles, G.J. Cook, V. Goh, Assessment of tumor heterogeneity: an emerging imaging tool for clinical practice?, Insights Imaging 3(6) (2012) 573–89.
Article PubMed PubMed Central Google Scholar
J.H. Yoon, J.M. Lee, W. Chang, H.J. Kang, A. Bandos, H.J. Lim, S.Y. Kang, K.W. Kang, S.B. Ryoo, S.Y. Jeong, K.J. Park, Initial M Staging of Rectal Cancer: FDG PET/MRI with a Hepatocyte-specific Contrast Agent versus Contrast-enhanced CT, Radiology 294(2) (2020) 310–319.
L. Zhang, S. Sanagapalli, A. Stoita, Challenges in diagnosis of pancreatic cancer, World J Gastroenterol 24(19) (2018) 2047–2060.
Article PubMed PubMed Central Google Scholar
M.M. Al-Hawary, I.R. Francis, S.T. Chari, E.K. Fishman, D.M. Hough, D.S. Lu, M. Macari, A.J. Megibow, F.H. Miller, K.J. Mortele, N.B. Merchant, R.M. Minter, E.P. Tamm, D.V. Sahani, D.M. Simeone, Pancreatic ductal adenocarcinoma radiology reporting template: consensus statement of the Society of Abdominal Radiology and the American Pancreatic Association, Radiology 270(1) (2014) 248 – 60.
R.J. Gillies, P.E. Kinahan, H. Hricak, Radiomics: Images Are More than Pictures, They Are Data, Radiology 278(2) (2016) 563 – 77.
P. Lambin, E. Rios-Velazquez, R. Leijenaar, S. Carvalho, R.G. van Stiphout, P. Granton, C.M. Zegers, R. Gillies, R. Boellard, A. Dekker, H.J. Aerts, Radiomics: extracting more information from medical images using advanced feature analysis, Eur J Cancer 48(4) (2012) 441–6.
Article PubMed PubMed Central Google Scholar
H. Tharmaseelan, A. Hertel, F. Tollens, J. Rink, P. Woźnicki, V. Haselmann, I. Ayx, D. Nörenberg, S.O. Schoenberg, M.F. Froelich, Identification of CT Imaging Phenotypes of Colorectal Liver Metastases from Radiomics Signatures—Towards Assessment of Interlesional Tumor Heterogeneity, Cancers 14(7) (2022).
H. Tharmaseelan, A.K. Vellala, A. Hertel, F. Tollens, L.T. Rotkopf, J. Rink, P. Woznicki, I. Ayx, S. Bartling, D. Norenberg, S.O. Schoenberg, M.F. Froelich, Tumor classification of gastrointestinal liver metastases using CT-based radiomics and deep learning, Cancer Imaging 23(1) (2023) 95.
Article PubMed PubMed Central Google Scholar
T. Henry, R. Sun, M. Lerousseau, T. Estienne, C. Robert, B. Besse, C. Robert, N. Paragios, E. Deutsch, Investigation of radiomics based intra-patient inter-tumor heterogeneity and the impact of tumor subsampling strategies, Sci Rep 12(1) (2022) 17244.
Article CAS PubMed PubMed Central Google Scholar
S. Park, J.G. Sham, S. Kawamoto, A.B. Blair, N. Rozich, D.F. Fouladi, S. Shayesteh, R.H. Hruban, J. He, C.L. Wolfgang, A.L. Yuille, E.K. Fishman, L.C. Chu, CT Radiomics–Based Preoperative Survival Prediction in Patients with Pancreatic Ductal Adenocarcinoma, American Journal of Roentgenology 217(5) (2021) 1104–1112.
R. Hinzpeter, R. Kulanthaivelu, A. Kohan, L. Avery, N.A. Pham, C. Ortega, U. Metser, M. Haider, P. Veit-Haibach, CT Radiomics and Whole Genome Sequencing in Patients with Pancreatic Ductal Adenocarcinoma: Predictive Radiogenomics Modeling, Cancers (Basel) 14(24) (2022).
Y. Gao, S. Cheng, L. Zhu, Q. Wang, W. Deng, Z. Sun, S. Wang, H. Xue, A systematic review of prognosis predictive role of radiomics in pancreatic cancer: heterogeneity markers or statistical tricks?, Eur Radiol 32(12) (2022) 8443–8452.
F. Isensee, P.F. Jaeger, S.A.A. Kohl, J. Petersen, K.H. Maier-Hein, nnU-Net: a self-configuring method for deep learning-based biomedical image segmentation, Nat Methods 18(2) (2021) 203–211.
Article CAS PubMed Google Scholar
J.J.M. van Griethuysen, A. Fedorov, C. Parmar, A. Hosny, N. Aucoin, V. Narayan, R.G.H. Beets-Tan, J.C. Fillion-Robin, S. Pieper, H. Aerts, Computational Radiomics System to Decode the Radiographic Phenotype, Cancer Res 77(21) (2017) e104-e107.
PubMed PubMed Central Google Scholar
S. Rizzo, F. Botta, S. Raimondi, D. Origgi, C. Fanciullo, A.G. Morganti, M. Bellomi, Radiomics: the facts and the challenges of image analysis, Eur Radiol Exp 2(1) (2018) 36.
Article PubMed PubMed Central Google Scholar
Y. Masugi, The Desmoplastic Stroma of Pancreatic Cancer: Multilayered Levels of Heterogeneity, Clinical Significance, and Therapeutic Opportunities, Cancers (Basel) 14(13) (2022).
G. Siravegna, L. Lazzari, G. Crisafulli, A. Sartore-Bianchi, B. Mussolin, A. Cassingena, C. Martino, R.B. Lanman, R.J. Nagy, S. Fairclough, G. Rospo, G. Corti, A. Bartolini, P. Arcella, M. Montone, F. Lodi, A. Lorenzato, A. Vanzati, E. Valtorta, G. Cappello, A. Bertotti, S. Lonardi, V. Zagonel, F. Leone, M. Russo, A. Balsamo, M. Truini, F. Di Nicolantonio, A. Amatu, E. Bonazzina, S. Ghezzi, D. Regge, A. Vanzulli, L. Trusolino, S. Siena, S. Marsoni, A. Bardelli, Radiologic and Genomic Evolution of Individual Metastases during HER2 Blockade in Colorectal Cancer, (1878–3686 (Electronic)) (2018).
K. Schmelz, J. Toedling, M. Huska, M.C. Cwikla, L.M. Kruetzfeldt, J. Proba, P.F. Ambros, I.M. Ambros, S. Boral, M. Lodrini, C.Y. Chen, M. Burkert, D. Guergen, A. Szymansky, K. Astrahantseff, A. Kuenkele, K. Haase, M. Fischer, H.E. Deubzer, F. Hertwig, P. Hundsdoerfer, A.G. Henssen, R.F. Schwarz, J.H. Schulte, A. Eggert, Spatial and temporal intratumour heterogeneity has potential consequences for single biopsy-based neuroblastoma treatment decisions, Nat Commun 12(1) (2021) 6804.
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