The authors thank all the member of the Medit-Ageing Research Group: Claire André, Eider M. Arenaza-Urquijo, Pierre Champetier, Gaël Chételat, Anne Chocat, Fabienne Collette, Robin de Florès, Vincent de La Sayette, Marion Delarue, Francesca Felisatti, Egantine Ferrand Devouge, Antoine Garnier-Crussard, Julie Gonneaud, Marc Heidmann, Frank Jessen, Olga Klimecki, Elizabeth Kuhn, Brigitte Landeau, Gwendoline Le Du, Valérie Lefranc, Antoine Lutz, Natalie L. Marchant, Florence Mézenge, Inès Moulinet, Valentin Ourry, Cassandre Palix, Léo Paly, Géraldine Poisnel, Stefano Poletti, Anne Quillard, Géraldine Rauchs, Stéphane Réhel, Eric Salmon, Siya Sherif, Edelweiss Touron, Matthier Vanhoutte, Denis Vivien, Patrik Vuilleumier, Caitlin Ware and Miranka Wirth. The authors also thank Marine Faure, Jeanne Lepetit, Marie Saville, and the Cyceron MRI-PET staff members for their assistance with recruitment and neuroimaging data acquisition; INSERM administrative, financial, and legal departments; INSERM Transfert (Delphine Smagghe) and Aurélia Cognet for administrative support; the sponsor (Pole de Recherche Clinique at INSERM, Dr. Hélène Espérou); the Euclid Team (Dr Eric Frison) for data management; and the participants of the study and their families.

The Medit-Ageing Research Group: list of Authors and affiliations:

Claire André, PhD1, Eider M. Arenaza-Urquijo, PhD7, Pierre Champetier PhD1, Gaël Chételat, PhD1, Anne Chocat, MD1, Fabienne Collette, PhD8−19, Robin de Florès, PhD1, Vincent de La Sayette MD3, Marion Delarue, MSc1, Francesca Felisatti, PhD1, Egantine Ferrand-Devouge, MD1,9, Antoine Garnier-Crussard, MD-MSc1,10, Julie Gonneaud, PhD1, Marc Heidmann, PhD11, Frank Jessen, MD-PhD12,13, Olga Klimecki, PhD14, Elizabeth Kuhn, PhD12,15, Brigitte Landeau, PhD1, Gwendoline Le Du, MSc1, Valérie Lefranc, BA1, Antoine Lutz, PhD16, Natalie L. Marchant, PhD17, Florence Mezenge, BA1, Inès Moulinet, PhD1, Valentin Ourry, PhD1, Cassandre Palix, PhD1, Léo Paly, MSc1, Géraldine Poisnel, PhD1, Stefano Poletti, MSc16, Anne Quillard, PhD1, Géraldine Rauchs, PhD1, Stéphane Réhel, PhD1, Eric Salmon, MD-PhD8−18, Siya Sherif, PhD8, Edelweiss Touron, PhD1, Matthieu Vanhoutte, PhD1, Denis Vivien, PhD1−4, Patrik Vuilleumier, MD20, Caitlin Ware, MSc1−21, and Miranka Wirth, PhD22.

7Environment and Health Over the Life Course Programme, Climate, Air Pollution, Nature and Urban Health Programme, Barcelona Institute for Global Health (ISGlobal), Barcelona, Spain

8Centre de recherche du Cyclotron, Université de Liège, 4000 Liège, Belgique

9Centre d’Investigation Clinique-Centre de Recherche Biologique 1404, Rouen University Hospital, Rouen, France

10Clinical and Research Memory Center of Lyon, Lyon Institute For Aging, Charpennes Hospital, Hospices Civils de Lyon, Lyon, France

11Institut National de la Santé et de la Recherche Médicale, Lyon, France

12German Center for Neurodegenerative Diseases (DZNE), Bonn, Bonn, Germany

13Department of Psychiatry, University of Cologne, Medical Faculty, Cologne, Germany

14Interim Chair of Biological Psychology, Technische Universität Dresden, Germany

15Department of Old Age Psychiatry and Cognitive Disorders, University of Bonn Medical Center, Bonn, Germany

16EDUWELL team, Lyon Neuroscience Research Centre, INSERM U1028, CNRS UMR 5292, Lyon 1 University, Lyon, France

17Division of Psychiatry, University College London, London, UK

18Centre de la mémoire, université de Liège, CHU, 4000 Liège, Belgique

19Département de psychologie, cognition et comportement, université de Liège, 4000 Liège, Belgique

20Department of Neurosciences and Clinic of Neurology, Laboratory for Neurology and Imaging of Cognition, University of Geneva, 1211 Geneva, Switzerland

21CRPMS, Université de Paris, Paris, France

22German Center for Neurodegenerative Diseases, Dresden, Germany