PRKACB is a novel imprinted gene in marsupials

Adhami HA, Evano B, Digarcher AL, Gueydan C, Dubois E, Parrinello H, et al. A systems-level approach to parental genomic imprinting: the imprinted gene network includes extracellular matrix genes and regulates cell cycle exit and differentiation. Genome Res. 2015;25:353–67.

Article  PubMed  PubMed Central  Google Scholar 

Babak T, DeVeale B, Tsang EK, Zhou Y, Li X, Smith KS, et al. Genetic conflict reflected in tissue-specific maps of genomic imprinting in human and mouse. Nat Genet. 2015;47:544–9.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bartolomei MS, Ferguson-Smith AC. Mammalian genomic imprinting. Cold Spring Harb Perspect Biol. 2011;3:a002592.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bathgate RAD, Siebel AL, Tovote P, Claasz A, Macris M, Parry LJ. Purification and characterization of relaxin from the tammar wallaby (Macropus eugenii): bioactivity and expression in the corpus luteum. Biol Reprod. 2002;67:293–300.

Article  CAS  PubMed  Google Scholar 

Bennetts L, Lin M, Aitken RJ. Cyclic AMP-dependent tyrosine phosphorylation in tammar wallaby (Macropus eugenii) spermatozoa. J Exp Zool. 2004;301A:118–30.

Article  CAS  Google Scholar 

Benson G. Tandem repeats finder: a program to analyze DNA sequences. Nucleic Acids Res. 1999;27:573–80.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Beuschlein F, Fassnacht M, Assié G, Calebiro D, Stratakis CA, Osswald A, et al. Constitutive activation of PKA catalytic subunit in adrenal Cushing’s syndrome. N Engl J Med. 2014;370:1019–28.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bond DM, Ortega-Recalde O, Laird MK, Hayakawa T, Richardson KS, FinlayCB R, et al. The admixed brushtail possum genome reveals invasion history in New Zealand and novel imprinted genes. Nat Commun. 2023;14:6364.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bonthuis PJ, Huang W-C, Stacher Hörndli CN, Ferris E, Cheng T, Gregg C. Noncanonical genomic imprinting effects in offspring. Cell Rep. 2015;12:979–91.

Article  CAS  PubMed  Google Scholar 

Cao W, Douglas KC, Samollow PB, VandeBerg JL, Wang X, Clark AG. Origin and evolution of marsupial-specific imprinting clusters through lineage-specific gene duplications and acquisition of promoter differential methylation (M Wilson, Ed.). Mol Biol Evol. 2023;40:22.

Article  Google Scholar 

Chen Y, Gao Y, Tian Y, Tian D-L. PRKACB is downregulated in non-small cell lung cancer and exogenous PRKACB inhibits proliferation and invasion of LTEP-A2 cells. Oncol Lett. 2013;5:1803–8.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chotalia M, Smallwood SA, Ruf N, Dawson C, Lucifero D, Frontera M, et al. Transcription is required for establishment of germline methylation marks at imprinted genes. Genes Dev. 2009;23:105–17.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Das R, Anderson N, Koran MI, Weidman JR, Mikkelsen TS, Kamal M, et al. Convergent and divergent evolution of genomic imprinting in the marsupial. BMC Genom. 2012;13:1–13.

Article  Google Scholar 

Douglas KC, Wang X, Jasti M, Wolff A, VandeBerg JL, Clark AG, et al. Genome-wide histone state profiling of fibroblasts from the opossum, Monodelphis domestica, identifies the first marsupial-specific imprinted gene. BMC Genom. 2014;15:89.

Article  Google Scholar 

Duffié R, Ajjan S, Greenberg MV, Zamudio N. The Gpr1/Zdbf2 locus provides new paradigms for transient and dynamic genomic imprinting in mammals. Genes Dev. 2014;28:463–78.

Article  PubMed  PubMed Central  Google Scholar 

Dunnet MJ, Ortega-Recalde OJ, Waters SA, Weeks RJ, Morison IM, Hore TA. Leukocyte-specific DNA methylation biomarkers and their implication for pathological epigenetic analysis. Epigenet Commun. 2022;2:5.

Article  Google Scholar 

Edwards CA, Takahashi N, Corish JA, Ferguson-Smith AC. The origins of genomic imprinting in mammals. Reprod Fertil Dev. 2019;31:1203–18.

Article  PubMed  Google Scholar 

Espiard S, Drougat L, Settas N, Haydar S, Bathon K, London E, et al. PRKACB variants in skeletal disease or adrenocortical hyperplasia: effects on protein kinase A. Endocr Relat Cancer. 2020;27:647–56.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Espiard S, Knape MJ, Bathon K, Assié G, Rizk-Rabin M, Faillot S, et al. Activating PRKACB somatic mutation in cortisol-producing adenomas. JCI Insight. 2018;3:e98296.

Article  PubMed  PubMed Central  Google Scholar 

Forlino A, Vetro A, Garavelli L, Ciccone R, London E, Stratakis CA, et al. PRKACB and carney complex. N Engl J Med. 2014;370:1065–7.

Article  CAS  PubMed  Google Scholar 

Freyer C, Renfree MB. The mammalian yolk sac placenta. J Exp Zool B Mol Dev Evol. 2009;312B:545–54.

Article  Google Scholar 

Frommer M, McDonald LE, Millar DS, Collis CM, Watt F, Grigg GW, et al. A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands. Proc Natl Acad Sci. 1992;89:1827–31.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gamm DM, Baude EJ, Uhler MD. The major catalytic subunit isoforms of cAMP-dependent protein kinase have distinct biochemical properties in vitro and in vivo. J Biol Chem. 1996;271:15736–42.

Article  CAS  PubMed  Google Scholar 

Grant J, Mahadevaiah SK, Khil P, Sangrithi MN, Royo H, Duckworth J, et al. Rsx is a metatherian RNA with Xist-like properties in X-chromosome inactivation. Nature. 2012;487:254–8.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Green B, Merchant J, Newgrain K. Milk consumption and energetics of growth in pouch young of the tammar wallaby, Macropus eugenii. Aust J Zool. 1988;36:217.

Article  Google Scholar 

Haig D. The kinship theory of genomic imprinting. Annu Rev Ecol Syst. 2000;31:9–32.

Article  Google Scholar 

Hamada H, Okae H, Toh H, Chiba H, Hiura H, Shirane K, et al. Allele-specific methylome and transcriptome analysis reveals widespread imprinting in the human placenta. Am J Hum Genet. 2016;99:1045–58.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hamed M, Ismael S, Paulsen M, Helms V. Cellular functions of genetically imprinted genes in human and mouse as annotated in the gene ontology. PLoS ONE. 2012;7:e50285.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hanna CW. Placental imprinting: emerging mechanisms and functions. PLoS Genet. 2020;16:e1008709.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Harris RS. Improved pairwise alignment of genomic DNA. University Park: The Pennsylvania State University; 2007.

Google Scholar 

Hayward BE, Barlier A, Korbonits M, Grossman AB, Jacquet P, Enjalbert A, et al. Imprinting of the Gsα gene GNAS1 in the pathogenesis of acromegaly. J Clin Invest. 2001;107:R31–6.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Holmes R, Williamson C, Peters J, Denny P. A comprehensive transcript map of the mouse Gnas imprinted complex. Genome Res. 2003;13:141–1415.

Article  Google Scholar 

Comments (0)

No login
gif