Ferlay J, Colombet M, Soerjomataram I, Parkin DM, Pineros M, Znaor A, et al. Cancer statistics for the year 2020: an overview. Int J Cancer. 2021;149:778–89.
Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, et al. Global Cancer statistics 2020: GLOBOCAN estimates of incidence and Mortality Worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2021;71:209–49.
Milella M, Rutigliano M, Lasorsa F, Ferro M, Bianchi R, Fallara G, et al. The role of MUC1 in renal cell carcinoma. Biomolecules. 2024;14:315.
Article CAS PubMed PubMed Central Google Scholar
Linehan WM, Ricketts CJ. The Cancer Genome Atlas of renal cell carcinoma: findings and clinical implications. Nat Rev Urol. 2019;16:539–52.
Article CAS PubMed Google Scholar
Cairns P. Renal cell carcinoma. Cancer Biomark. 2010;9:461–73.
Lasorsa F, Rutigliano M, Milella M, Ferro M, Pandolfo SD, Crocetto F, et al. Cellular and Molecular players in the tumor microenvironment of renal cell carcinoma. J Clin Med. 2023;12:3888.
Article CAS PubMed PubMed Central Google Scholar
Netti GS, Lucarelli G, Spadaccino F, Castellano G, Gigante M, Divella C, et al. PTX3 modulates the immunoflogosis in tumor microenvironment and is a prognostic factor for patients with clear cell renal cell carcinoma. Aging. 2020;12:7585–602.
Article PubMed PubMed Central Google Scholar
Lucarelli G, Rutigliano M, Ferro M, Giglio A, Intini A, Triggiano F, et al. Activation of the kynurenine pathway predicts poor outcome in patients with clear cell renal cell carcinoma. Urol Oncol. 2017;35:461-e15- e27.
Lasorsa F, Rutigliano M, Milella M, Ferro M, Pandolfo SD, Crocetto F, et al. Complement system and the kidney: its role in renal diseases, kidney transplantation and renal cell carcinoma. Int J Mol Sci. 2023;24:16515.
Article CAS PubMed PubMed Central Google Scholar
Ghini V, Laera L, Fantechi B, Monte FD, Benelli M, McCartney A, et al. Metabolomics to assess response to immune checkpoint inhibitors in patients with non-small-cell lung cancer. Cancers 2020;12:13574.
Lasorsa F, di Meo NA, Rutigliano M, Milella M, Ferro M, Pandolfo SD, et al. Immune checkpoint inhibitors in renal cell carcinoma: molecular basis and rationale for their use in clinical practice. Biomedicines. 2023;11:1071.
Article CAS PubMed PubMed Central Google Scholar
Luo Y, Shen D, Chen L, Wang G, Liu X, Qian K, et al. Identification of 9 key genes and small molecule drugs in clear cell renal cell carcinoma. Aging. 2019;11:6029–52.
Article CAS PubMed PubMed Central Google Scholar
Xu WH, Xu Y, Wang J, Wan FN, Wang HK, Cao DL, et al. Prognostic value and immune infiltration of novel signatures in clear cell renal cell carcinoma microenvironment. Aging. 2019;11:6999–7020.
Article CAS PubMed PubMed Central Google Scholar
Wolf MM, Kimryn Rathmell W, Beckermann KE. Modeling clear cell renal cell carcinoma and therapeutic implications. Oncogene. 2020;39:3413–26.
Article CAS PubMed PubMed Central Google Scholar
Yao J, Subramanian C, Rock CO, Jackowski S. Human pantothenate kinase 4 is a pseudo-pantothenate kinase. Protein Sci. 2019;28:1031–47.
Article CAS PubMed PubMed Central Google Scholar
Dansie LE, Reeves S, Miller K, Zano SP, Frank M, Pate C, et al. Physiological roles of the pantothenate kinases. Biochem Soc Trans. 2014;42:1033–6.
Article CAS PubMed PubMed Central Google Scholar
Iacobas DA, Tuli NY, Iacobas S, Rasamny JK, Moscatello A, Geliebter J, et al. Gene master regulators of papillary and anaplastic thyroid cancers. Oncotarget. 2018;9:2410–24.
Liu Y, Cheng Z, Li Q, Pang Y, Cui L, Qian T, et al. Prognostic significance of the PANK family expression in acute myeloid leukemia. Ann Transl Med. 2019;7:261.
Article CAS PubMed PubMed Central Google Scholar
Audam TN, Howard CM, Garrett LF, Zheng YW, Bradley JA, Brittian KR, et al. Cardiac PANK1 deletion exacerbates ventricular dysfunction during pressure overload. Am J Physiol Heart Circ Physiol. 2021;321:H784–97.
Article CAS PubMed PubMed Central Google Scholar
Leonardi R, Rock CO, Jackowski S. Pank1 deletion in leptin-deficient mice reduces hyperglycaemia and hyperinsulinaemia and modifies global metabolism without affecting insulin resistance. Diabetologia. 2014;57:1466–75.
Article CAS PubMed PubMed Central Google Scholar
Yang L, Zhang B, Wang X, Liu Z, Li J, Zhang S, et al. P53/PANK1/miR-107 signalling pathway spans the gap between metabolic reprogramming and insulin resistance induced by high-fat diet. J Cell Mol Med. 2020;24:3611–24.
Article CAS PubMed PubMed Central Google Scholar
Kluth M, Galal R, Krohn A, Weischenfeldt J, Tsourlakis C, Paustian L, et al. Prevalence of chromosomal rearrangements involving non-ETS genes in prostate cancer. Int J Oncol. 2015;46:1637–42.
Article CAS PubMed Google Scholar
Kfir-Erenfeld S, Haggiag N, Biton M, Stepensky P, Assayag-Asherie N, Yefenof E. miR-103 inhibits proliferation and sensitizes hemopoietic tumor cells for glucocorticoid-induced apoptosis. Oncotarget. 2017;8:472–89.
Song N, Ma X, Li H, Zhang Y, Wang X, Zhou P, et al. microRNA-107 functions as a candidate tumor suppressor gene in renal clear cell carcinoma involving multiple genes. Urol Oncol. 2015;33:e2051–11.
Chandrashekar DS, Bashel B, Balasubramanya SAH, Creighton CJ, Ponce-Rodriguez I, Chakravarthi B, et al. UALCAN: a portal for facilitating Tumor Subgroup Gene expression and survival analyses. Neoplasia. 2017;19:649–58.
Article CAS PubMed PubMed Central Google Scholar
Tang Z, Li C, Kang B, Gao G, Li C, Zhang Z. GEPIA: a web server for cancer and normal gene expression profiling and interactive analyses. Nucleic Acids Res. 2017;45:W98–102.
Article CAS PubMed PubMed Central Google Scholar
Vasaikar SV, Straub P, Wang J, Zhang B. LinkedOmics: analyzing multi-omics data within and across 32 cancer types. Nucleic Acids Res. 2018;46:D956–63.
Article CAS PubMed Google Scholar
Vuong L, Kotecha RR, Voss MH, Hakimi AA. Tumor Microenvironment dynamics in Clear-Cell Renal Cell Carcinoma. Cancer Discov. 2019;9:1349–57.
Article CAS PubMed PubMed Central Google Scholar
Tamma R, Rutigliano M, Lucarelli G, Annese T, Ruggieri S, Cascardi E, et al. Microvascular density, macrophages, and mast cells in human clear cell renal carcinoma with and without bevacizumab treatment. Urol Oncol. 2019;37:355-e11- e19.
Lucarelli G, Netti GS, Rutigliano M, Lasorsa F, Loizzo D, Milella M, et al. MUC1 expression affects the immunoflogosis in renal cell carcinoma microenvironment through complement system activation and immune infiltrate modulation. Int J Mol Sci. 2023;24:4814.
Comments (0)