Mattson MP, Arumugam TV. Hallmarks of brain aging: adaptive and pathological modification by metabolic states. Cell Metab. 2018;27(6):1176–99.
Article CAS PubMed PubMed Central Google Scholar
For the Alzheimer’s Disease Neuroimaging Initiative, Camargo A, Wang Z. Longitudinal cerebral blood flow changes in normal aging and the Alzheimer’s disease continuum identified by arterial spin labeling MRI. JAD. 2021;81(4):1727–35.
Camargo A, Wang Z, For the Alzheimer’s Disease Neuroimaging Initiative. Hypo- and hyper-perfusion in MCI and AD identified by different ASL MRI sequences. Brain Imaging Behav. 2023;17(3):306–19.
Article PubMed PubMed Central Google Scholar
McKeith IG, Boeve BF, Dickson DW, Halliday G, Taylor JP, Weintraub D, et al. Diagnosis and management of dementia with Lewy bodies: fourth consensus report of the DLB Consortium. Neurology. 2017;89(1):88–100.
Article PubMed PubMed Central Google Scholar
Thal DR, Del Tredici K, Braak H. Neurodegeneration in normal brain aging and disease. Sci Aging Knowl Environ [Internet]. 2004;2004(23). https://doi.org/10.1126/sageke.2004.23.pe26.
Wolfova K, Kucera M, Cermakova P. Risk and protective factors of neurocognitive disorders in older adults in Central and Eastern Europe: a systematic review of population-based studies. In: Bayer A (ed) PLoS ONE. 2021;16(11):e0260549.
Hou Y, Dan X, Babbar M, Wei Y, Hasselbalch SG, Croteau DL, et al. Ageing as a risk factor for neurodegenerative disease. Nat Rev Neurol. 2019;15(10):565–81.
Azam S, Haque MdE, Balakrishnan R, Kim IS, Choi DK. The ageing brain: molecular and cellular basis of neurodegeneration. Front Cell Dev Biol. 2021;9:683459.
Article PubMed PubMed Central Google Scholar
Bateman RJ, Xiong C, Benzinger TLS, Fagan AM, Goate A, Fox NC, et al. Clinical and biomarker changes in dominantly inherited Alzheimer’s disease. N Engl J Med. 2012;367(9):795–804.
Article CAS PubMed PubMed Central Google Scholar
Saito Y, Ruberu NN, Sawabe M, Arai T, Kazama H, Hosoi T, et al. Lewy body-related α-synucleinopathy in aging. J Neuropathol Exp Neurol. 2004;63(7):742–9.
Spillantini MG, Schmidt ML, Lee VMY, Trojanowski JQ, Jakes R, Goedert M. α-Synuclein in Lewy bodies. Nature. 1997;388(6645):839–40.
Article CAS PubMed Google Scholar
Wong YC, Krainc D. α-synuclein toxicity in neurodegeneration: mechanism and therapeutic strategies. Nat Med. 2017;23(2):1–13.
Article CAS PubMed PubMed Central Google Scholar
McKeith IG, Galasko D, Kosaka K, Perry EK, Dickson DW, Hansen LA, et al. Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB): report of the consortium on DLB international workshop. Neurology. 1996;47(5):1113–24.
Article CAS PubMed Google Scholar
Aarsland D, Andersen K, Larsen JP, Lolk A. Prevalence and characteristics of dementia in Parkinson disease: an 8-year prospective study. Arch Neurol. 2003;60(3):387.
Bousiges O, Blanc F. Biomarkers of dementia with Lewy bodies: differential diagnostic with Alzheimer’s disease. IJMS. 2022;23(12):6371.
Article CAS PubMed PubMed Central Google Scholar
McKeith IG, Ferman TJ, Thomas AJ, Blanc F, Boeve BF, Fujishiro H, et al. Research criteria for the diagnosis of prodromal dementia with Lewy bodies. Neurology. 2020;94(17):743–55.
Article PubMed PubMed Central Google Scholar
Blanc F, Colloby SJ, Philippi N, De Pétigny X, Jung B, Demuynck C, et al. Cortical thickness in dementia with Lewy bodies and Alzheimer’s disease: a comparison of prodromal and dementia stages. He Y, editor. PLoS ONE. 2015;10(6):e0127396.
Blanc F, Noblet V, Philippi N, Cretin B, Foucher J, Armspach JP, et al. Right anterior insula: core region of hallucinations in cognitive neurodegenerative diseases. Chao L, editor. PLoS ONE. 2014;9(12):e114774.
Blanc F, Colloby SJ, Cretin B, De Sousa PL, Demuynck C, O’Brien JT, et al. Grey matter atrophy in prodromal stage of dementia with Lewy bodies and Alzheimer’s disease. Alz Res Therapy. 2016;8(1):31.
Blanc F, Bouteloup V, Paquet C, Chupin M, Pasquier F, Gabelle A, et al. Prodromal characteristics of dementia with Lewy bodies: baseline results of the MEMENTO memory clinics nationwide cohort. Alz Res Therapy. 2022;14(1):96.
Roquet D, Noblet V, Anthony P, Philippi N, Demuynck C, Cretin B, et al. Insular atrophy at the prodromal stage of dementia with Lewy bodies: a VBM DARTEL study. Sci Rep. 2017;7(1):9437.
Article PubMed PubMed Central Google Scholar
Galvin JE, Duda JE, Kaufer DI, Lippa CF, Taylor A, Zarit SH. Lewy body dementia: the caregiver experience of clinical care. Parkinsonism Relat Disord. 2010;16(6):388–92.
Article PubMed PubMed Central Google Scholar
Surendranathan A, Kane JPM, Bentley A, Barker SAH, Taylor JP, Thomas AJ, et al. Clinical diagnosis of Lewy body dementia. BJPsych Open. 2020;6(4): e61.
Article PubMed PubMed Central Google Scholar
McKeith IG, Dickson DW, Lowe J, Emre M, O’Brien JT, Feldman H, et al. Diagnosis and management of dementia with Lewy bodies: third report of the DLB consortium. Neurology. 2005;65(12):1863–72.
Article CAS PubMed Google Scholar
Baskys A. Lewy body dementia: the litmus test for neuroleptic sensitivity and extrapyramidal symptoms. J Clin Psychiatry. 2004;65(Suppl 11):16–22.
Rossi M, Candelise N, Baiardi S, Capellari S, Giannini G, Orrù CD, et al. Ultrasensitive RT-QuIC assay with high sensitivity and specificity for Lewy body-associated synucleinopathies. Acta Neuropathol. 2020;140(1):49–62.
Article CAS PubMed PubMed Central Google Scholar
Fairfoul G, McGuire LI, Pal S, Ironside JW, Neumann J, Christie S, et al. Alpha-synuclein RT -Qu IC in the CSF of patients with alpha-synucleinopathies. Ann Clin Transl Neurol. 2016;3(10):812–8.
Article CAS PubMed PubMed Central Google Scholar
Bongianni M, Ladogana A, Capaldi S, Klotz S, Baiardi S, Cagnin A, et al. α-Synuclein RT-QuIC assay in cerebrospinal fluid of patients with dementia with Lewy bodies. Ann Clin Transl Neurol. 2019;6(10):2120–6.
Article CAS PubMed PubMed Central Google Scholar
Bargar C, Wang W, Gunzler SA, LeFevre A, Wang Z, Lerner AJ, et al. Streamlined alpha-synuclein RT-QuIC assay for various biospecimens in Parkinson’s disease and dementia with Lewy bodies. Acta Neuropathol Commun. 2021;9(1):62.
Article CAS PubMed PubMed Central Google Scholar
Groveman BR, Orrù CD, Hughson AG, Raymond LD, Zanusso G, Ghetti B, et al. Rapid and ultra-sensitive quantitation of disease-associated α-synuclein seeds in brain and cerebrospinal fluid by αSyn RT-QuIC. Acta Neuropathol Commun. 2018;6(1):7.
Article PubMed PubMed Central Google Scholar
Roquet D, Sourty M, Botzung A, Armspach JP, Blanc F. Brain perfusion in dementia with Lewy bodies and Alzheimer’s disease: an arterial spin labeling MRI study on prodromal and mild dementia stages. Alz Res Therapy. 2016;8(1):29.
Zhong J, Pan P, Dai Z, Shi H. Voxelwise meta-analysis of gray matter abnormalities in dementia with Lewy bodies. Eur J Radiol. 2014;83(10):1870–4.
Firbank MJ, Durcan R, O’Brien JT, Allan LM, Barker S, Ciafone J, et al. Hippocampal and insula volume in mild cognitive impairment with Lewy bodies. Parkinsonism Relat Disord. 2021;86:27–33.
Article CAS PubMed Google Scholar
Goto H, Ishii K, Uemura T, Miyamoto N, Yoshikawa T, Shimada K, et al. Differential diagnosis of dementia with Lewy bodies and Alzheimer disease using combined MR imaging and brain perfusion single-photon emission tomography. AJNR Am J Neuroradiol. 2010;31(4):720–5.
Article CAS PubMed PubMed Central Google Scholar
Nedelska Z, Senjem ML, Przybelski SA, Lesnick TG, Lowe VJ, Boeve BF, et al. Regional cortical perfusion on arterial spin labeling MRI in dementia with Lewy bodies: Associations with clini
Comments (0)