Value-Added Nanocellulose Valorized from Fruit Peel Waste for Potential Dermal Wound Healing and Tissue Regenerative Applications

Singh S, Chunglok W, Nwabor OF, Chulrik W, Jansakun C, Bhoopong P. Porous biodegradable sodium alginate composite fortified with Hibiscus sabdariffa L. calyx extract for the multifarious biological applications and extension of climacteric fruit shelf-life. J Polym Environ. 2023;31(3):922–38. https://doi.org/10.1007/s10924-022-02596-x.

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Nwabor OF, Singh S, Marlina D, Voravuthikunchai SP. Chemical characterization, release, and bioactivity of Eucalyptus camaldulensis polyphenols from freeze-dried sodium alginate and sodium carboxymethyl cellulose matrix. Food Qual Saf. 2020;4(4):203–12. https://doi.org/10.1093/fqsafe/fyaa016.

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Sharma R, Malviya R, Singh S, Prajapati B. A critical review on classified excipient sodium-alginate-based hydrogels: modification, characterization, and application in soft tissue engineering. Gels. 2023;9(5):430.

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Ontong JC, Singh S, Nwabor OF, Chusri S, Voravuthikunchai SP. Potential of antimicrobial topical gel with synthesized biogenic silver nanoparticle using Rhodomyrtus tomentosa leaf extract and silk sericin. Biotech Lett. 2020;42(12):2653–64. https://doi.org/10.1007/s10529-020-02971-5.

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Chorachoo Ontong J, Singh S, Nwabor OF, Chusri S, Kaewnam W, Kanokwiroon K, Septama AW, Panichayupakaranant P, Voravuthikunchai SP. Microwave-assisted extract of rhodomyrtone from rhodomyrtus tomentosa leaf: anti-inflammatory, antibacterial, antioxidant, and safety assessment of topical rhodomyrtone formulation. Sep Sci Technol. 2023;58(5):929–943. https://doi.org/10.1080/01496395.2023.2169162.

Chittasupho C, Chaobankrang K, Sarawungkad A, Samee W, Singh S, Hemsuwimon K, Okonogi S, Kheawfu K, Kiattisin K, Chaiyana W. Antioxidant, anti-inflammatory and attenuating intracellular reactive oxygen species activities of Nicotiana tabacum var. virginia leaf extract phytosomes and shape memory gel formulation. Gels. 2023;9(2):78.

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Karati D, Mukherjee S, Singh S, Prajapati BG, Basu B. Biopolymer-based nano-formulations for mitigation of ocular infections: a review. Polym Bull. 2023. https://doi.org/10.1007/s00289-023-05095-8.

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Alotaibi G, Alharthi S, Basu B, Ash D, Dutta S, Singh S, Prajapati BG, Bhattacharya S, Chidrawar VR, Chitme H. Nano-gels: recent advancement in fabrication methods for mitigation of skin cancer. Gels. 2023;9(4):331.

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Begum RF, Singh S, Prajapati B, Sumithra M, Patel RJ. Advanced targeted drug delivery of bioactive agents fortified with graft chitosan in management of cancer: a review. Curr Med Chem. 2024;38415441. https://doi.org/10.2174/0109298673285334240112104709.

Mukherjee S, Karati D, Singh S, Prajapati BG. Chitosan-based nanomedicine in the management of age-related macular degeneration: a review. Curr Nanomed. 2024;14(1):13–27. https://doi.org/10.2174/0124681873261772230927074628.

Nwabor OF, Singh S, Paosen S, Vongkamjan K, Voravuthikunchai SP. Enhancement of food shelf life with polyvinyl alcohol-chitosan nanocomposite films from bioactive Eucalyptus leaf extracts. Food Biosci. 2020;36:100609. https://doi.org/10.1016/j.fbio.2020.100609.

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Eze FN, Jayeoye TJ, Singh S. Fabrication of intelligent pH-sensing films with antioxidant potential for monitoring shrimp freshness via the fortification of chitosan matrix with broken Riceberry phenolic extract. Food Chem. 2022;366:130574. https://doi.org/10.1016/j.foodchem.2021.130574.

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Mohite P, Shah SR, Singh S, Rajput T, Munde S, Ade N, Prajapati BG, Paliwal H, Mori DD, Dudhrejiya AV. Chitosan and chito-oligosaccharide: a versatile biopolymer with endless grafting possibilities for multifarious applications. Front Bioeng Biotechnol. 2023;11:1190879. https://doi.org/10.3389/fbioe.2023.1190879.

Mohite P, Rahayu P, Munde S, Ade N, Chidrawar VR, Singh S, Jayeoye TJ, Prajapati BG, Bhattacharya S, Patel RJ. Chitosan-based hydrogel in the management of dermal infections: a review. Gels. 2023;9(7):594.

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Pawar A, Lohakane P, Pandhare R, Mohite P, Munde S, Singh S, Chidrawar V. Chitosan fortified repaglinide gastro-retentive mucoadhesive microsphere with improved anti-diabetic attribute. Intell Pharm. 2024. https://doi.org/10.1016/j.ipha.2024.01.012.

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Singh S, Nwabor OF, Ontong JC, Kaewnopparat N, Voravuthikunchai SP. Characterization of a novel, co-processed bio-based polymer, and its effect on mucoadhesive strength. Int J Biol Macromol. 2020;145:865–75. https://doi.org/10.1016/j.ijbiomac.2019.11.198.

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Singh S, Nwabor OF, Ontong JC, Voravuthikunchai SP. Characterization and assessment of compression and compactibility of novel spray-dried, co-processed bio-based polymer. J Drug Deliv Sci Technol. 2020;56:101526. https://doi.org/10.1016/j.jddst.2020.101526.

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Chidrawar VR, Singh S, Jayeoye TJ, Dodiya R, Samee W, Chittasupho C. Porous swellable hypromellose composite fortified with Eucalyptus camaldulensis leaf hydrophobic/hydrophilic phenolic-rich extract to mitigate dermal wound infections. J Polym Environ. 2023;31(9):3841–56. https://doi.org/10.1007/s10924-023-02860-8.

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Singh S, Chidrawar VR, Hermawan D, Dodiya R, Samee W, Ontong JC, Ushir YV, Prajapati BG, Chittasupho C. Hypromellose highly swellable composite fortified with Psidium guajava leaf phenolic-rich extract for antioxidative, antibacterial, anti-inflammatory, anti-melanogenesis, and hemostasis applications. J Polym Environ. 2023. https://doi.org/10.1007/s10924-023-02819-9.

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Singh S, Chunglok W, Nwabor OF, Ushir YV, Singh S, Panpipat W. Hydrophilic biopolymer matrix antibacterial peel-off facial mask functionalized with biogenic nanostructured material for cosmeceutical applications. J Polym Environ. 2022;30(3):938–53. https://doi.org/10.1007/s10924-021-02249-5.

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Singh S, Chittasupho C, Prajapati BG, Chandel AS. Editorial: biodegradable polymeric materials in tissue engineering and their application in drug delivery. Front Bioeng Biotechnol. 2023;11:1296119. https://doi.org/10.3389/fbioe.2023.1296119.

Vyas J, Shah I, Singh S, Prajapati BG. Biomaterials-based additive manufacturing for customized bioengineering in management of otolaryngology: a comprehensive review. Front Bioeng Biotechnol. 2023;11:1234340. https://doi.org/10.3389/fbioe.2023.1234340.

Ontong JC, Singh S, Siriyong T, Voravuthikunchai SP. Transferosomes stabilized hydrogel incorporated rhodomyrtone-rich extract from Rhodomyrtus tomentosa leaf fortified with phosphatidylcholine for the management of skin and soft-tissue infections. Biotech Lett. 2024;46(1):127–42. https://doi.org/10.1007/s10529-023-03452-1.

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Singh S, Dodiya TR, Dodiya R, Ushir YV, Widodo S. Lipid nanoparticulate drug delivery systems: approaches toward improvement in therapeutic efficacy of bioactive molecules. In: Luis Jesús V-G, editor. Drug carriers. Rijeka: IntechOpen; 2022. p. 10. https://doi.org/10.5772/intechopen.104510.

Kapoor DU, Gaur M, Parihar A, Prajapati BG, Singh S, Patel RJ. Phosphatidylcholine (PCL) fortified nano-phytopharmaceuticals for improvement of therapeutic efficacy. EXCLI J. 2023;22:880–903.

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Mohite P, Singh S, Pawar A, Sangale A, Prajapati BG. Lipid-based oral formulation in capsules to improve the delivery of poorly water-soluble drugs. Front Drug Deliv. 2023;3:1232012. https://doi.org/10.3389/fddev.2023.1232012.

Singh S, Supaweera N, Nwabor OF, Chaichompoo W, Suksamrarn A, Chittasupho C, Chunglok W. Poly (vinyl alcohol)-gelatin-sericin copolymerized film fortified with vesicle-entrapped demethoxycurcumin/bisdemethoxycurcumin for improved stability, antibacterial, anti-inflammatory, and skin tissue regeneration. Int J Biol Macromol. 2024;258:129071. https://doi.org/10.1016/j.ijbiomac.2023.129071.

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Singh S, Ushir YV, Prajapati BG. Phytosomes and herbosomes: a vesicular drug delivery system for improving the bioavailability of natural products. In: Prajapati B aPJ, editor. Lipid-based drug delivery systems: principles and applications. London: Jenny Stanford Publishing; 2023. pp. 1–38. https://doi.org/10.1201/9781003459811.

Shah S, Chauhan H, Madhu H, Mori D, Soniwala M, Singh S, Prajapati B. Lipids fortified nano phytopharmaceuticals: a breakthrough approach in delivering bio-actives for improved therapeutic efficacy. Pharm Nanotechnol. 2024;12:38279712. https://doi.org/10.2174/0122117385277686231127050723.

Patel P, Garala K, Singh S, Prajapati BG, Chittasupho C. Lipid-based nanoparticles in delivering bioactive compounds for improving therapeutic efficacy. Pharmaceuticals. 2024;17(3):329.

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Kapoor D, Chilkapalli SC, Prajapati BG, Rodriques P, Patel R, Singh S, Bhattacharya S. The astonishing accomplishment of biological drug delivery using lipid nanoparticles: an ubiquitous review. Curr Pharm Biotechnol. 2024;25:38265380. https://doi.org/10.2174/0113892010268824231122041237.

Singh SA, Vellapandian C, Shah DD, Jayeoye TJ, Chorawala MR, Singh S, Prajapati BG. Valorised calcium-rich biomass from fish waste and eggshells in the fabrication of antibacterial scaffold for wound healing applications: a review. Waste Biomass Valorization. 2023. https://doi.org/10.1007/s12649-023-02302-5.

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Solway DR, Clark WA, Levinson DJ. A parallel open-label trial to evaluate microbial cellulose wound dressing in the treatment of diabetic foot ulcers. Int Wound J. 2011;8(1):69–73.

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Singh S, Nwabor OF, Sukri DM, Wunnoo S, Dumjun K, Lethongkam S, Kusolphat P, Hemtanon N, Klinprathum K, Sunghan J, Dejyong K, Lertwittayanon K, Pisuchpen S, Voravuthikunchai SP. Poly (vinyl alcohol) copolymerized with xanthan gum/hypromellose/sodium carboxymethyl cellulose dermal dressings functionalized with biogenic nanostructured materials for antibacterial and wound healing application. Int J Biol Macromol. 2022;216:235–50. https://doi.org/10.1016/j.ijbiomac.2022.06.172.

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