Role of ZNF334 in cervical cancer: implications for EMT reversal and tumor suppression

Siegel RL, Miller KD, Wagle NS, et al. Cancer statistics, 2023. CA Cancer J Clin. 2023;73(1):17–48.

Article  PubMed  Google Scholar 

Perkins RB, Wentzensen N, Guido RS, et al. Cervical cancer screening: a review. JAMA. 2023;330(6):547–58.

Article  CAS  PubMed  Google Scholar 

Zhu B, Liu Q, Han Q, et al. Downregulation of Krüppel-like factor 1 inhibits the metastasis and invasion of cervical cancer cells. Mol Med Rep. 2018;18(4):3932–40.

CAS  PubMed  PubMed Central  Google Scholar 

Chan DW, Yu SY, Chiu PM, et al. Over-expression of FOXM1 transcription factor is associated with cervical cancer progression and pathogenesis. J Pathol. 2008;215(3):245–52.

Article  CAS  PubMed  Google Scholar 

Zhang Z, Peng J, Li B, et al. HOXA1 promotes aerobic glycolysis and cancer progression in cervical cancer. Cell Signal. 2023;109: 110747.

Article  CAS  PubMed  Google Scholar 

Huang H, Han Q, Zheng H, et al. MAP4K4 mediates the SOX6-induced autophagy and reduces the chemosensitivity of cervical cancer. Cell Death Dis. 2021;13(1):13.

Article  PubMed  PubMed Central  Google Scholar 

Li L, Gong Y, Xu K, et al. ZBTB28 induces autophagy by regulation of FIP200 and Bcl-XL facilitating cervical cancer cell apoptosis. J Exp Clin Cancer Res. 2021;40(1):150.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ni M, Li J, Zhao H, et al. BRD4 inhibition sensitizes cervical cancer to radiotherapy by attenuating DNA repair. Oncogene. 2021;40(15):2711–24.

Article  CAS  PubMed  Google Scholar 

Yang WT, Zheng PS. Krüppel-like factor 4 functions as a tumor suppressor in cervical carcinoma. Cancer. 2012;118(15):3691–702.

Article  CAS  PubMed  Google Scholar 

Cheng Z, Yu R, Li L, et al. Disruption of ZNF334 promotes triple-negative breast carcinoma malignancy through the SFRP1/ Wnt/β-catenin signaling axis. Cell Mol Life Sci. 2022;79(5):280.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Yang B, Tang H, Wang N, et al. Targeted DNA demethylation of the ZNF334 promoter inhibits colorectal cancer growth. Cell Death Dis. 2023;14(3):210.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gerstberger S, Jiang Q, Ganesh K. Metastasis. Cell. 2023;186(8):1564–79.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bakir B, Chiarella AM, Pitarresi JR, et al. EMT, MET, plasticity, and tumor metastasis. Trends Cell Biol. 2020;30(10):764–76.

Article  PubMed  PubMed Central  Google Scholar 

Aiello NM, Maddipati R, Norgard RJ, et al. EMT subtype influences epithelial plasticity and mode of cell migration. Dev Cell. 2018;45(6):681-95.e4.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Prakash V, Carson BB, Feenstra JM, et al. Ribosome biogenesis during cell cycle arrest fuels EMT in development and disease. Nat Commun. 2019;10(1):2110.

Article  PubMed  PubMed Central  Google Scholar 

Hudson DM, Weis M, Rai J, et al. P3h3-null and Sc65-null mice phenocopy the collagen lysine under-hydroxylation and cross-linking abnormality of ehlers-danlos syndrome type VIA. J Biol Chem. 2017;292(9):3877–87.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Pokidysheva E, Boudko S, Vranka J, et al. Biological role of prolyl 3-hydroxylation in type IV collagen. Proc Natl Acad Sci U S A. 2014;111(1):161–6.

Article  CAS  PubMed  Google Scholar 

Singh D, Vignat J, Lorenzoni V, et al. Global estimates of incidence and mortality of cervical cancer in 2020: a baseline analysis of the WHO Global cervical cancer elimination initiative. Lancet Glob Health. 2023;11(2):e197–206.

Article  CAS  PubMed  Google Scholar 

Cohen PA, Jhingran A, Oaknin A, et al. Cervical cancer. Lancet. 2019;393(10167):169–82.

Article  PubMed  Google Scholar 

Jeannot E, Latouche A, Bonneau C, et al. Circulating HPV DNA as a marker for early detection of relapse in patients with cervical cancer. Clin Cancer Res. 2021;27(21):5869–77.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Qiu J, Qu X, Wang Y, et al. Single-cell landscape highlights heterogenous microenvironment, novel immune reaction patterns, potential biomarkers and unique therapeutic strategies of cervical squamous carcinoma, human papillomavirus-associated (HPVA) and non-HPVA adenocarcinoma. Adv Sci (Weinh). 2023;10(10):e2204951.

Article  PubMed  Google Scholar 

van den Helder R, Steenbergen RDM, van Splunter AP, et al. HPV and DNA methylation testing in urine for cervical intraepithelial neoplasia and cervical cancer detection. Clin Cancer Res. 2022;28(10):2061–8.

Article  PubMed  Google Scholar 

Chaffer CL, Weinberg RA. A perspective on cancer cell metastasis. Science. 2011;331(6024):1559–64.

Article  CAS  PubMed  Google Scholar 

Fares J, Fares MY, Khachfe HH, et al. Molecular principles of metastasis: a hallmark of cancer revisited. Signal Transduct Target Ther. 2020;5(1):28.

Article  PubMed  PubMed Central  Google Scholar 

Yuan Z, Li Y, Zhang S, et al. Extracellular matrix remodeling in tumor progression and immune escape: from mechanisms to treatments. Mol Cancer. 2023;22(1):48.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Winkler J, Abisoye-Ogunniyan A, Metcalf KJ, et al. Concepts of extracellular matrix remodelling in tumour progression and metastasis. Nat Commun. 2020;11(1):5120.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Su H, Karin M. Multifaceted collagen-DDR1 signaling in cancer. Trends Cell Biol. 2023. https://doi.org/10.1016/j.tcb.2023.08.003.

Article  PubMed  Google Scholar 

Armstrong T, Packham G, Murphy LB, et al. Type I collagen promotes the malignant phenotype of pancreatic ductal adenocarcinoma. Clin Cancer Res. 2004;10(21):7427–37.

Article  CAS  PubMed  Google Scholar 

Chen Y, Yang S, Tavormina J, et al. Oncogenic collagen I homotrimers from cancer cells bind to α3β1 integrin and impact tumor microbiome and immunity to promote pancreatic cancer. Cancer Cell. 2022;40(8):818-34.e9.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cheon DJ, Tong Y, Sim MS, et al. A collagen-remodeling gene signature regulated by TGF-β signaling is associated with metastasis and poor survival in serous ovarian cancer. Clin Cancer Res. 2014;20(3):711–23.

Article  CAS  PubMed  Google Scholar 

Ishikawa Y, Taga Y, Zientek K, et al. Type I and type V procollagen triple helix uses different subsets of the molecular ensemble for lysine posttranslational modifications in the rER

Comments (0)

No login
gif