Disease activity and widespread pain are main contributors to patient-reported global health in axial spondyloarthritis: an analysis of 6064 patients

Kiltz U, Essers I, Hiligsmann M, Braun J, Maksymowych WP, Taylor WJ, van der Heijde D, Boonen A (2016) Which aspects of health are most important for patients with spondyloarthritis? A Best Worst Scaling based on the ASAS Health Index. Rheumatology (Oxford) 55(10):1771–1776. https://doi.org/10.1093/rheumatology/kew238

Article  PubMed  Google Scholar 

Navarro-Compán V, Sepriano A, El-Zorkany B, van der Heijde D (2021) Axial spondyloarthritis. Ann Rheum Dis 80(12):1511–1521. https://doi.org/10.1136/annrheumdis-2021-221035

Article  CAS  PubMed  Google Scholar 

Puyraimond-Zemmour D, Granger B, Molto A, Gaujoux-Viala C, Guillemin F, Ruyssen-Witrand A, Dougados M, Fautrel B, Gossec L (2019) Similar alteration for mental and physical aspects in health-related quality of life over 5 to 8 years in 1347 patients with early arthritis and early inflammatory back pain. Arthritis Res Ther 21(1):63. https://doi.org/10.1186/s13075-019-1841-y

Article  PubMed  PubMed Central  Google Scholar 

Dean LE, Macfarlane GJ, Jones GT (2018) Five potentially modifiable factors predict poor quality of life in ankylosing spondylitis: results from the Scotland registry for ankylosing spondylitis. J Rheumatol 45(1):62–69. https://doi.org/10.3899/jrheum.160411

Article  PubMed  Google Scholar 

Elolemy G, Aboughanima A, Ganeb S, Elziat H (2020) Health-related quality of life in patients with ankylosing spondylitis: relationship with disease-related variables. Curr Rheumatol Rev 16(4):311–318. https://doi.org/10.2174/1573397115666191018162606

Article  CAS  PubMed  Google Scholar 

Kotsis K, Voulgari PV, Drosos AA, Carvalho AF, Hyphantis T (2014) Health-related quality of life in patients with ankylosing spondylitis: a comprehensive review. Expert Rev Pharmacoecon Outcomes Res 14(6):857–872. https://doi.org/10.1586/14737167.2014.957679

Article  PubMed  Google Scholar 

Carvalho PD, Ruyssen-Witrand A, Marreiros A, Machado PM (2022) Long-term association between disease activity and disability in early axial spondyloarthritis: results from a prospective observational study of inflammatory back pain. Arthritis Care Res 74(5):768–775. https://doi.org/10.1002/acr.24515

Article  Google Scholar 

Fernández-Carballido C, Navarro-Compán V, Castillo-Gallego C, Castro-Villegas MC, Collantes-Estévez E, de Miguel E (2017) Disease activity as a major determinant of quality of life and physical function in patients with early axial spondyloarthritis. Arthritis Care Res 69(1):150–155. https://doi.org/10.1002/acr.22908

Article  CAS  Google Scholar 

Kwan YH, Fong W, Leung YY, Lui NL, Tan CS, Malhotra R, Østbye T, Thumboo J (2019) Are extra-spinal symptoms associated with quality of life in patients with axial spondyloarthritis? A 1-year follow-up study. Clin Rheumatol 38(7):1881–1887. https://doi.org/10.1007/s10067-019-04514-4

Article  PubMed  Google Scholar 

Marzo-Ortega H, Navarro-Compán V, Akar S, Kiltz U, Clark Z, Nikiphorou E (2022) The impact of gender and sex on diagnosis, treatment outcomes and health-related quality of life in patients with axial spondyloarthritis. Clin Rheumatol 41(11):3573–3581. https://doi.org/10.1007/s10067-022-06228-6

Article  PubMed  PubMed Central  Google Scholar 

Huang J-C, Qian B-P, Qiu Y, Wang B, Yu Y, Zhu Z-Z, Hu J, Qu Z (2017) Quality of life and correlation with clinical and radiographic variables in patients with ankylosing spondylitis: a retrospective case series study. BMC Musculoskelet Disord 18(1):352. https://doi.org/10.1186/s12891-017-1711-1

Article  PubMed  PubMed Central  Google Scholar 

van der Meer R, Arends S, Kruidhof S, Bos R, Bootsma H, Wink F, Spoorenberg A (2022) Extraskeletal manifestations in axial spondyloarthritis are associated with worse clinical outcomes despite the use of tumor necrosis factor inhibitor therapy. J Rheumatol 49(2):157–164. https://doi.org/10.3899/jrheum.210308

Article  PubMed  Google Scholar 

Macfarlane GJ, Rotariu O, Jones GT, Pathan E, Dean LE (2020) Determining factors related to poor quality of life in patients with axial spondyloarthritis: results from the British Society for Rheumatology Biologics Register (BSRBR-AS). Ann Rheum Dis 79(2):202–208. https://doi.org/10.1136/annrheumdis-2019-216143

Article  CAS  PubMed  Google Scholar 

Moltó A, Etcheto A, van der Heijde D, Landewé R, van den Bosch F, Bautista Molano W, Burgos-Vargas R, Cheung PP, Collantes-Estevez E, Deodhar A, El-Zorkany B, Erdes S, Gu J, Hajjaj-Hassouni N, Kiltz U, Kim T-H, Kishimoto M, Luo S-F, Machado PM et al (2016) Prevalence of comorbidities and evaluation of their screening in spondyloarthritis: results of the international cross-sectional ASAS-COMOSPA study. Ann Rheumatic Dis 75(6):1016–1023. https://doi.org/10.1136/annrheumdis-2015-208174

Article  CAS  Google Scholar 

Redeker I, Hoffmann F, Callhoff J, Haibel H, Sieper J, Zink A, Poddubnyy D (2018) Determinants of psychological well-being in axial spondyloarthritis: an analysis based on linked claims and patient-reported survey data. Ann Rheum Dis 77(7):1017–1024. https://doi.org/10.1136/annrheumdis-2017-212629

Article  CAS  PubMed  Google Scholar 

Macfarlane GJ, Barnish MS, Pathan E, Martin KR, Haywood KL, Siebert S, Packham J, Atzeni F, Jones GT (2017) Co-occurrence and characteristics of patients with axial spondyloarthritis who meet criteria for fibromyalgia: results from a UK National Register. Arthritis Rheumatol (Hoboken, NJ) 69(11):2144–2150. https://doi.org/10.1002/art.40185

Article  Google Scholar 

Duffield SJ, Miller N, Zhao S, Goodson NJ (2018) Concomitant fibromyalgia complicating chronic inflammatory arthritis: a systematic review and meta-analysis. Rheumatology (Oxford) 57(8):1453–1460. https://doi.org/10.1093/rheumatology/key112

Article  PubMed  Google Scholar 

Tournadre A, Pereira B, Lhoste A, Dubost JJ, Ristori JM, Claudepierre P, Dougados M, Soubrier M (2013) Differences between women and men with recent-onset axial spondyloarthritis: results from a prospective multicenter French cohort. Arthritis Care Res 65(9):1482–1489. https://doi.org/10.1002/acr.22001

Article  CAS  Google Scholar 

Hollick RJ, Stelfox K, Dean LE, Shim J, Walker-Bone K, Macfarlane GJ (2020) Outcomes and treatment responses, including work productivity, among people with axial spondyloarthritis living in urban and rural areas: a mixed-methods study within a national register. Ann Rheum Dis 79(8):1055–1062. https://doi.org/10.1136/annrheumdis-2020-216988

Article  PubMed  Google Scholar 

Machado P, Landewé R, Braun J, Hermann K-GA, Baraliakos X, Baker D, Hsu B, van der Heijde D (2011) A stratified model for health outcomes in ankylosing spondylitis. Ann Rheum Dis 70(10):1758–1764. https://doi.org/10.1136/ard.2011.150037

Article  PubMed  Google Scholar 

López-Medina C, Garrido-Castro JL, Castro-Jiménez J, González-Navas C, Calvo-Gutiérrez J, Castro-Villegas MC, Ortega-Castro R, Escudero-Contreras A, Font-Ugalde P, Collantes-Estévez E (2018) Evaluation of quality of life in patients with axial spondyloarthritis and its association with disease activity, functionality, mobility, and structural damage. Clin Rheumatol 37(6):1581–1588. https://doi.org/10.1007/s10067-018-4112-4

Article  PubMed  Google Scholar 

Dougados M, Etcheto A, Molto A, Alonso S, Bouvet S, Daurès J-P, Landais P, d’Agostino M-A, Berenbaum F, Breban M, Claudepierre P, Combe B, Fautrel B, Feydy A, Goupille P, Richette P, Pham T, Roux C, Treluyer J-M et al (2015) Clinical presentation of patients suffering from recent onset chronic inflammatory back pain suggestive of spondyloarthritis: the DESIR cohort. Joint Bone Spine 82(5):345–351. https://doi.org/10.1016/j.jbspin.2015.02.006

Article  PubMed  Google Scholar 

Molto A, Gossec L, Poiraudeau S, Claudepierre P, Soubrier M, Fayet F, Wendling D, Gaudin P, Dernis E, Guis S, Pouplin S, Ruyssen-Witrand A, Chales G, Mariette X, Beauvais C, Combe B, Flipo R-M, Richette P, Chary-Valckenaere I et al (2021) Evaluation of the impact of a nurse-led program of patient self-assessment and self-management in axial spondyloarthritis: results of a prospective, multicentre, randomized, controlled trial (COMEDSPA). Rheumatology (Oxford) 60(2):888–895. https://doi.org/10.1093/rheumatology/keaa480

Article  PubMed  Google Scholar 

López-Medina C, Molto A, Sieper J, Duruöz T, Kiltz U, Elzorkany B, Hajjaj-Hassouni N, Burgos-Vargas R, Maldonado-Cocco J, Ziade N, Gavali M, Navarro-Compan V, Luo S-F, Monti S, Tae-Jong K, Kishimoto M, Pimentel-Santos FM, Gu J, Schiotis R et al (2021) Prevalence and distribution of peripheral musculoskeletal manifestations in spondyloarthritis including psoriatic arthritis: results of the worldwide, cross-sectional ASAS-PerSpA study. RMD Open 7(1):e001450. https://doi.org/10.1136/rmdopen-2020-001450

Article  PubMed  PubMed Central  Google Scholar 

Kiltz U, van der Heijde D, Boonen A, Akkoc N, Bautista-Molano W, Burgos-Vargas R, Wei JC-C, Chiowchanwisawakit P, Dougados M, Duruoz MT, Elzorkany BK, Gaydukova I, Gensler LS, Gilio M, Grazio S, Gu J, Inman RD, Kim T-J, Navarro-Compan V et al (2018) Measurement properties of the ASAS Health Index: results of a global study in patients with axial and peripheral spondyloarthritis. Ann Rheum Dis 77(9):1311–1317. https://doi.org/10.1136/annrheumdis-2017-212076

Article  PubMed  Google Scholar 

Euroqol User Guide https://www.euroqol.org/publications/user-guides

Kiltz U, van der Heijde D, Boonen A, Cieza A, Stucki G, Khan MA, Maksymowych WP, Marzo-Ortega H, Reveille J, Stebbings S, Bostan C, Braun J (2015) Development of a health index in patients with ankylosing spondylitis (ASAS HI): final result of a global initiative based on the ICF guided by ASAS. Ann Rheum Dis 74(5):830–835. https://doi.org/10.1136/annrheumdis-2013-203967

Article  CAS  PubMed 

Comments (0)

No login
gif