H. Sung, J. Ferlay, R.L. Siegel, M. Laversanne, I. Soerjomataram, A. Jemal, F. Bray, Global cancer statistics 2020: globocan estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA A Cancer J. Clin. 71(3), 209–249 (2021)

Article  Google Scholar 

M. Rugge, Gastric cancer risk: between genetics and lifestyle. Lancet Oncol. 21(10), 1258–1260 (2020)

Article  PubMed  Google Scholar 

E.C. Smyth, M. Nilsson, H.I. Grabsch, N.C. van Grieken, F. Lordick, Gastric cancer. Lancet 396(10251), 635–648 (2020)

Article  CAS  PubMed  Google Scholar 

J. Ferlay, H.R. Shin, F. Bray, D. Forman, C. Mathers, D.M. Parkin, Estimates of worldwide burden of cancer in 2008: globocan 2008. Int. J. Cancer 127(12), 2893–2917 (2010)

Article  CAS  PubMed  Google Scholar 

M. Venerito, A. Link, T. Rokkas, P. Malfertheiner, Gastric cancer - clinical and epidemiological aspects. Helicobacter 21(Suppl 1), 39–44 (2016)

Article  PubMed  Google Scholar 

M.J. Lopez, J. Carbajal, A.L. Alfaro, L.G. Saravia, D. Zanabria, J.M. Araujo, L. Quispe, A. Zevallos, J.L. Buleje, C.E. Cho, M. Sarmiento, J.A. Pinto, W. Fajardo, Characteristics of gastric cancer around the world. Crit. Rev. Oncol. Hematol. 181, 103841 (2023)

Article  PubMed  Google Scholar 

V. Pasechnikov, S. Chukov, E. Fedorov, I. Kikuste, M. Leja, Gastric cancer: prevention, screening and early diagnosis. World J. Gastroenterol. 20(38), 13842–13862 (2014)

Article  PubMed  PubMed Central  Google Scholar 

M. Ito, S. Tanaka, K. Chayama, Characteristics and early diagnosis of gastric cancer discovered after helicobacter pylori eradication. Gut. Liver 15(3), 338–345 (2021)

Article  PubMed  Google Scholar 

L. Necula, L. Matei, D. Dragu, A.I. Neagu, C. Mambet, S. Nedeianu, C. Bleotu, C.C. Diaconu, M. Chivu-Economescu, Recent advances in gastric cancer early diagnosis. World J. Gastroenterol. 25(17), 2029–2044 (2019)

Article  CAS  PubMed  PubMed Central  Google Scholar 

P. Karimi, F. Islami, S. Anandasabapathy, N.D. Freedman, F. Kamangar, Gastric cancer: descriptive epidemiology, risk factors, screening, and prevention. Cancer Epidemiol. Biomarkers Prev. 23(5), 700–713 (2014)

Article  PubMed  PubMed Central  Google Scholar 

J. Machlowska, J. Baj, M. Sitarz, R. Maciejewski, R. Sitarz, Gastric cancer: epidemiology, risk factors, classification, genomic characteristics and treatment strategies. Int. J. Mol. Sci. 21(11) (2020)

M. Cavaleiro-Pinto, B. Peleteiro, N. Lunet, H. Barros, Helicobacter pylori infection and gastric cardia cancer: systematic review and meta-analysis. Cancer Causes Control. 22(3), 375–387 (2011)

Article  PubMed  Google Scholar 

E. Yakirevich, M.B. Resnick, Pathology of gastric cancer and its precursor lesions. Gastroenterol. Clin. North Am. 42(2), 261–284 (2013)

Article  PubMed  Google Scholar 

L. Yang, C. Kartsonaki, P. Yao, C. de Martel, M. Plummer, D. Chapman, Y. Guo, S. Clark, R.G. Walters, Y. Chen, P. Pei, J. Lv, C. Yu, R. Jeske, T. Waterboer, G.M. Clifford, S. Franceschi, R. Peto, M. Hill, L. Li, I.Y. Millwood, Z. Chen, G. China Kadoorie Biobank Collaborative, The relative and attributable risks of cardia and non-cardia gastric cancer associated with helicobacter pylori infection in china: a case-cohort study. Lancet Public Health 6(12), 888–896 (2021)

Article  Google Scholar 

P. Lauren, The two histological main types of gastric carcinoma: diffuse and so-called intestinal-type carcinoma. an attempt at a histo-clinical classification. Acta Pathol. Microbiol. Scand. 64, 31–49 (1965)

Article  CAS  PubMed  Google Scholar 

B. Hu, N. El Hajj, S. Sittler, N. Lammert, R. Barnes, A. Meloni-Ehrig, Gastric cancer: classification, histology and application of molecular pathology. J. Gastrointest. Oncol. 3(3), 251–261 (2012)

PubMed  PubMed Central  Google Scholar 

K.M. Kim, M.S. Kwon, S.J. Hong, K.O. Min, E.J. Seo, K.Y. Lee, S.W. Choi, M.G.J.V.A. Rhyu, Genetic classification of intestinal-type and diffuse-type gastric cancers based on chromosomal loss and microsatellite instability. Virchows Arch. 443(4), 491–500 (2003)

Article  PubMed  Google Scholar 

S.T. Tay, S.H. Leong, K. Yu, A. Aggarwal, S.Y. Tan, C.H. Lee, K. Wong, J. Visvanathan, D. Lim, W.K. Wong, K.C. Soo, O.L. Kon, P. Tan, A combined comparative genomic hybridization and expression microarray analysis of gastric cancer reveals novel molecular subtypes. Cancer Res. 63(12), 3309–3316 (2003)

CAS  PubMed  Google Scholar 

I.B. Tan, T. Ivanova, K.H. Lim, C.W. Ong, N. Deng, J. Lee, S.H. Tan, J. Wu, M.H. Lee, C.H. Ooi, S.Y. Rha, W.K. Wong, A. Boussioutas, K.G. Yeoh, J. So, W.P. Yong, A. Tsuburaya, H. Grabsch, H.C. Toh, S. Rozen, J.H. Cheong, S.H. Noh, W.K. Wan, J.A. Ajani, J.S. Lee, M.S. Tellez, P. Tan, Intrinsic subtypes of gastric cancer, based on gene expression pattern, predict survival and respond differently to chemotherapy. Gastroenterology 141(2), 476–85485111 (2011)

Article  PubMed  Google Scholar 

Z. Lei, I.B. Tan, K. Das, N. Deng, H. Zouridis, S. Pattison, C. Chua, Z. Feng, Y.K. Guan, C.H. Ooi, T. Ivanova, S. Zhang, M. Lee, J. Wu, A. Ngo, S. Manesh, E. Tan, B.T. Teh, J.B. So, L.K. Goh, A. Boussioutas, T.K. Lim, H. Flotow, P. Tan, S.G. Rozen, Identification of molecular subtypes of gastric cancer with different responses to pi3-kinase inhibitors and 5-fluorouracil. Gastroenterology 145(3), 554–565 (2013)

Article  CAS  PubMed  Google Scholar 

N. Cancer Genome Atlas Research, Comprehensive molecular characterization of gastric adenocarcinoma. Nature 513(7517), 202–209 (2014)

Article  Google Scholar 

R. Cristescu, J. Lee, M. Nebozhyn, K.M. Kim, J.C. Ting, S.S. Wong, J. Liu, Y.G. Yue, J. Wang, K. Yu, X.S. Ye, I.G. Do, S. Liu, L. Gong, J. Fu, J.G. Jin, M.G. Choi, T.S. Sohn, J.H. Lee, J.M. Bae, S.T. Kim, S.H. Park, I. Sohn, S.H. Jung, P. Tan, R. Chen, J. Hardwick, W.K. Kang, M. Ayers, D. Hongyue, C. Reinhard, A. Loboda, S. Kim, A. Aggarwal, Molecular analysis of gastric cancer identifies subtypes associated with distinct clinical outcomes. Nat. Med. 21(5), 449–456 (2015)

Article  CAS  PubMed  Google Scholar 

E.O. Ignatova, E. Kozlov, M. Ivanov, V. Mileyko, S. Menshikova, H. Sun, M. Fedyanin, A. Tryakin, I. Stilidi, Clinical significance of molecular subtypes of gastrointestinal tract adenocarcinoma. World J. Gastrointest Oncol. 14(3), 628–645 (2022)

Article  PubMed  PubMed Central  Google Scholar 

P.J. Farrell, Epstein-barr virus and cancer. Annu. Rev. Pathol. 14, 29–53 (2019)

Article  CAS  PubMed  Google Scholar 

J.T. Schiller, D.R. Lowy, An introduction to virus infections and human cancer. Recent Results Cancer Res. 217, 1–11 (2021)

Article  CAS  PubMed  PubMed Central  Google Scholar 

M. Alsina, V. Arrazubi, M. Diez, J. Tabernero, Current developments in gastric cancer: from molecular profiling to treatment strategy. Nat. Rev. Gastroenterol. Hepatol. 20(3), 155–170 (2023)

Article  CAS  PubMed  Google Scholar 

A. Shinozaki-Ushiku, A. Kunita, M. Fukayama, Update on epstein-barr virus and gastric cancer (review). Int. J. Oncol. 46(4), 1421–1434 (2015)

Article  CAS  PubMed  Google Scholar 

Y. Du, J.Y. Zhang, L.P. Gong, Z.Y. Feng, D. Wang, Y.H. Pan, L.P. Sun, J.Y. Wen, G.F. Chen, J. Liang, J.N. Chen, C.K. Shao, Hypoxia-induced ebv- circlmp2a promotes angiogenesis in ebv-associated gastric carcinoma through the khsrp/vhl/hif1alpha/vegfa pathway. Cancer Lett. 526, 259–272 (2022)

Article  CAS  PubMed  Google Scholar 

J. Ribeiro, A. Oliveira, M. Malta, C. Oliveira, F. Silva, A. Galaghar, L.P. Afonso, M.C. Neves, R. Medeiros, P. Pimentel-Nunes, H. Sousa, Clinical and pathological characterization of epstein-barr virus-associated gastric carcinomas in portugal. World J. Gastroenterol. 23(40), 7292–7302 (2017)

Article  PubMed  PubMed Central  Google Scholar 

M. Naseem, A. Barzi, C. Brezden-Masley, A. Puccini, M.D. Berger, R. Tokunaga, F. Battaglin, S. Soni, M. McSkane, W. Zhang, H.J. Lenz, Outlooks on epstein-barr virus associated gastric cancer. Cancer Treat Rev. 66, 15–22 (2018)

Article  CAS  PubMed  PubMed Central  Google Scholar 

M.S. Chang, H. Uozaki, J.M. Chong, T. Ushiku, K. Sakuma, S. Ishikawa, R. Hino, R.R. Barua, Y. Iwasaki, K. Arai, H. Fujii, H. Nagai, M. Fukayama, Cpg island methylation status in gastric carcinoma with and without infection of epstein-barr virus. Clin. Cancer. Res. 12(10), 2995–3002 (2006)

Article  CAS  PubMed