Ruggiero, S. L. et al. American Association of Oral and Maxillofacial Surgeons position paper on medication-related osteonecrosis of the jaw-2014 update. J. Oral Maxillofac Surg. 72, 1938–1956 (2014).
Mucke, T. et al. Outcome of treatment and parameters influencing recurrence in patients with bisphosphonate-related osteonecrosis of the jaws. J. Cancer Res. Clin. Oncol. 137, 907–913 (2011).
Fliefel, R., Troltzsch, M., Kuhnisch, J., Ehrenfeld, M. & Otto, S. Treatment strategies and outcomes of bisphosphonate-related osteonecrosis of the jaw (BRONJ) with characterization of patients: a systematic review. Int. J. Oral Maxillofac Surg. 44, 568–585 (2015).
Article CAS PubMed Google Scholar
Crane, J. L. & Cao, X. Bone marrow mesenchymal stem cells and TGF-beta signaling in bone remodeling. J. Clin. Invest. 124, 466–472 (2014).
Article CAS PubMed PubMed Central Google Scholar
Gallagher, J. C. & Sai, A. J. Molecular biology of bone remodeling: implications for new therapeutic targets for osteoporosis. Maturitas 65, 301–307 (2010).
Article CAS PubMed PubMed Central Google Scholar
Marx, R. E., Sawatari, Y., Fortin, M. & Broumand, V. Bisphosphonate-induced exposed bone (osteonecrosis/osteopetrosis) of the jaws: risk factors, recognition, prevention, and treatment. J. Oral Maxillofac Surg. 63, 1567–1575 (2005).
He, L. H. et al. Role of bone marrow stromal cells in impaired bone repair from BRONJ Osseous Lesions. J. Dental Res. 96, 539–546 (2017).
Hu, L. et al. Apoptosis repressor with caspase recruitment domain enhances survival and promotes osteogenic differentiation of human osteoblast cells under Zoledronate treatment. Mol. Med. Rep. 14, 3535–3542 (2016).
Article CAS PubMed PubMed Central Google Scholar
Yan, W., Sheng, N., Seto, M., Morser, J. & Wu, Q. Corin, a mosaic transmembrane serine protease encoded by a novel cDNA from human heart. J. Biol. Chem. 274, 14926–14935 (1999).
Article CAS PubMed Google Scholar
Yan, W., Wu, F., Morser, J. & Wu, Q. Corin, a transmembrane cardiac serine protease, acts as a pro-atrial natriuretic peptide-converting enzyme. Proc. Natl Acad. Sci. USA 97, 8525–8529 (2000).
Article CAS PubMed PubMed Central Google Scholar
Nordberg, R. C., Wang, H., Wu, Q. & Loboa, E. G. Corin is a key regulator of endochondral ossification and bone development via modulation of vascular endothelial growth factor A expression. J. Tissue Eng. Regen Med. 12, 2277–2286 (2018).
Article CAS PubMed Google Scholar
Charoenpanich, A. et al. Microarray analysis of human adipose-derived stem cells in three-dimensional collagen culture: osteogenesis inhibits bone morphogenic protein and Wnt signaling pathways, and cyclic tensile strain causes upregulation of proinflammatory cytokine regulators and angiogenic factors. Tissue Eng Part A 17, 2615–2627 (2011).
Article CAS PubMed PubMed Central Google Scholar
Zhou, H., Zhu, J., Liu, M., Wu, Q. & Dong, N. Role of the protease corin in chondrogenic differentiation of human bone marrow-derived mesenchymal stem cells. J. Tissue Eng. Regen Med. 12, 973–982 (2018).
Article CAS PubMed Google Scholar
Jiang, J. et al. Ectodomain shedding and autocleavage of the cardiac membrane protease corin. J. Biol. Chem. 286, 10066–10072 (2011).
Article CAS PubMed PubMed Central Google Scholar
Dong, N. et al. Plasma soluble corin in patients with heart failure. Circ. Heart Fail 3, 207–211 (2010).
Article PubMed PubMed Central Google Scholar
Zhou, H. et al. Reduced serum corin levels in patients with osteoporosis. Clin. Chim. Acta 426, 152–156 (2013).
Article CAS PubMed Google Scholar
Alderman, M. H. 3rd & Xiao, A. Z. N(6)-Methyladenine in eukaryotes. Cell Mol. Life Sci. 76, 2957–2966 (2019).
Article CAS PubMed PubMed Central Google Scholar
Xie, L. et al. Emerging roles for DNA 6mA and RNA m6A methylation in mammalian genome. Int. J. Mol. Sci. 24, 13897 (2023).
Article CAS PubMed PubMed Central Google Scholar
Chen, L. S. et al. The m(6)A demethylase FTO promotes the osteogenesis of mesenchymal stem cells by downregulating PPARG. Acta Pharmacol. Sin. 43, 1311–1323 (2022).
Article CAS PubMed Google Scholar
Han, X. et al. METTL3 promotes osteo/odontogenic differentiation of stem cells by inhibiting miR-196b-5p maturation. Stem Cells Int. 2023, 8992284 (2023).
Article PubMed PubMed Central Google Scholar
Cheng, C. et al. METTL14 benefits the mesenchymal stem cells in patients with steroid-associated osteonecrosis of the femoral head by regulating the m6A level of PTPN6. Aging 13, 23903–25919 (2021).
Vera-Montecinos, A. et al. A novel localization of METTL7A in Bergmann Glial cells in human cerebellum. Int. J. Mol. Sci. 24, 8405 (2023).
Article CAS PubMed PubMed Central Google Scholar
Lee, E., Kim, J. Y., Kim, T. K., Park, S. Y. & Im, G. I. Methyltransferase-like protein 7A (METTL7A) promotes cell survival and osteogenic differentiation under metabolic stress. Cell Death Discov. 7, 154 (2021).
Article CAS PubMed PubMed Central Google Scholar
Wang, N., Han, X., Yang, H., Xia, D. & Fan, Z. miR-6807-5p inhibited the odontogenic differentiation of human dental pulp stem cells through directly targeting METTL7A. Front. Cell Dev. Biol. 9, 759192 (2021).
Article PubMed PubMed Central Google Scholar
Yi, X. et al. Candidate genes responsible for lipid droplets formation during adipogenesis simultaneously affect osteoblastogenesis. Histochem. Cytochem. 60, 89–100 (2022).
Wu, Y. et al. Mettl3-mediated m(6)A RNA methylation regulates the fate of bone marrow mesenchymal stem cells and osteoporosis. Nat. Commun. 9, 4772 (2018).
Article PubMed PubMed Central Google Scholar
Yang, H., Liang, Y., Cao, Y., Cao, Y. & Fan, Z. Homeobox C8 inhibited the osteo-/dentinogenic differentiation and migration ability of stem cells of the apical papilla via activating KDM1A. J. Cell. Physiol. 235, 8432–8445 (2020).
Article CAS PubMed Google Scholar
Baron, R., Ferrari, S. & Russell, R. G. Denosumab and bisphosphonates: different mechanisms of action and effects. Bone 48, 677–692 (2011).
Article CAS PubMed Google Scholar
Miano, J. M. Myocardin in biology and disease. J. Biomed. Res. 29, 3–19 (2015).
Tuan, N. M. & Lee, C. H. Role of Anillin in tumour: from a prognostic biomarker to a novel target. Cancers (Basel) 12, 1600 (2020).
Article CAS PubMed Google Scholar
Black, D. M. et al. Once-yearly zoledronic acid for treatment of postmenopausal osteoporosis. N. Engl. J. Med. 356, 1809–1821 (2007).
Comments (0)