Arbutin attenuates CFA-induced arthritis by modulating expression levels of 5-LOX, NF‑κB, IL-17, PGE-2 and TNF-α

Ahmadian SR, Ghasemi-Kasman M, Pouramir M, Sadeghi F (2019) Arbutin attenuates cognitive impairment and inflammatory response in pentylenetetrazol-induced kindling model of epilepsy. Neuropharmacology 146:117–127

Article  CAS  PubMed  Google Scholar 

Ahsan H, Irfan HM, Alamgeer, Shahzad M, Asim MH, Akram M et al (2021) Anti-rheumatic activity of pseudoephedrine (a substituted phenethylamine) in complete Freund’s adjuvant-induced arthritic rats by down regulating IL-1β, IL-6 and TNF-α as well as upregulating IL-4 and IL-10. Inflammopharmacology 29:673–682

Article  CAS  PubMed  Google Scholar 

Akhter S, Irfan HM, Alamgeer, Jahan S, Shahzad M, Latif MB (2022) Nerolidol: a potential approach in rheumatoid arthritis through reduction of TNF-α, IL-1β, IL-6, NF-kB, COX-2 and antioxidant effect in CFA-induced arthritic model. Inflammopharmacology 30(2):537–548

Article  CAS  PubMed  Google Scholar 

Alamgeer, Niazi SG, Uttra AM, Qaiser MN, Ahsan H (2017) Appraisal of anti-arthritic and nephroprotective potential of Cuscuta reflexa. Pharm Biol 55(1):792–798

Article  PubMed Central  Google Scholar 

Alunno A, Carubbi F, Giacomelli R, Gerli R (2017) Cytokines in the pathogenesis of rheumatoid arthritis: new players and therapeutic targets. BMC Rheumatology 1(1):1–13

Article  PubMed  PubMed Central  Google Scholar 

Arya V, Gupta VK, Kaur R (2011) A review on plants having anti-arthritic potential. Int J Pharm Sci Rev Res 7(2):131–136

Google Scholar 

Azam SS, Abbasi SW (2013) Molecular docking studies for the identification of novel melatoninergic inhibitors for acetylserotonin-O-methyltransferase using different docking routines. Theor Biol Med Model 10(1):1–16

Article  Google Scholar 

Baliyan S, Mukherjee R, Priyadarshini A, Vibhuti A, Gupta A, Pandey RP et al (2022) Determination of antioxidants by DPPH radical scavenging activity and quantitative phytochemical analysis of ficus religiosa. Molecules 27(4):1326

Article  CAS  PubMed  PubMed Central  Google Scholar 

Barksby H, Lea S, Preshaw P, Taylor J (2007) The expanding family of interleukin-1 cytokines and their role in destructive inflammatory disorders. Clin Exp Immunol 149(2):217–225

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bozkurt FY, Ay ZY, Berker E, Tepe E, Akkuş S (2006) Anti-inflammatory cytokines in gingival crevicular fluid in patients with periodontitis and rheumatoid arthritis: a preliminary report. Cytokine 35(3–4):180–185

Article  CAS  PubMed  Google Scholar 

Chakraborty M, Bhattacharya S, Bhattacharjee P, Das R, Mishra R (2010) Prevention of the progression of adjuvant induced arthritis by oral supplementation of Indian fresh water mussel (Lamellidens marginalis) aqueous extract in experimental rats. J Ethnopharmacol 132(1):316–320

Article  PubMed  Google Scholar 

El-Ashmawy NE, Khedr EG, Shamloula MM, Kamel MMJEB, & Medicine (2019) Evaluation of the antirheumatic effects of isoflavone-free soy protein isolate and etanercept in rats with adjuvant-induced arthritis. Exp Biol Med (Maywood) 244(7), 545–553

Fu Q, Wang L, Li L, Li Y, Liu R, Zheng YJCr (2019) Risk factors for progression and prognosis of rheumatoid arthritis–associated interstitial lung disease: single center study with a large sample of Chinese population. Clin Rheumatol 38:1109–1116

Gheorghe KR, Korotkova M, Catrina AI, Backman L, Af Klint E, Claesson, H-E, et al (2009) Expression of 5-lipoxygenase and 15-lipoxygenase in rheumatoid arthritis synovium and effects of intraarticular glucocorticoids. Arthritis Res Ther 11:1–11

Gohil P, Patel V, Deshpande S, Chorawala M, Shah G (2018) Anti-arthritic activity of cell wall content of Lactobacillus plantarum in freund’s adjuvant-induced arthritic rats: involvement of cellular inflammatory mediators and other biomarkers. Inflammopharmacology 26:171–181

Article  CAS  PubMed  Google Scholar 

Gul B, Anwar R, Saleem M, Noor A, Ullah MI (2023) C assia absus-mediated upregulation of IL-4, IL-10 and downregulation of IL-1β, IL-6, TNF-α, NF-κB, IFN-γ in CFA-induced arthritis model. Inflammopharmacology 31(3):1241–1256

Article  CAS  PubMed  Google Scholar 

Herawati H, Oktanella Y, Anisa A (2021) Molecular docking analysis of curcuminoids from curcuma longa extract on inos as an immunomodulator candidate in broilers. Adv Anim Vet Sci 9(4):519–524

Article  Google Scholar 

Iqubal A, Sharma S, Ansari MA, Najmi AK, Syed MA, Ali J et al (2019) Nerolidol attenuates cyclophosphamide-induced cardiac inflammation, apoptosis and fibrosis in Swiss Albino mice. Eur J Pharmacol 863:172666

Article  CAS  PubMed  Google Scholar 

Isaacs JD, Iqbal KJCT (2019) Potential pharmacologic targets for the prevention of rheumatoid arthritis. Clin Ther 41(7):1312–1322

Article  CAS  PubMed  Google Scholar 

Jitta SR, Daram P, Gourishetti K, Misra CS, Polu PR, Shah A et al (2019) Terminalia tomentosa bark ameliorates inflammation and arthritis in carrageenan induced inflammatory model and Freund’s adjuvant-induced arthritis model in rats. J Toxicol 2019:7898914. https://doi.org/10.1155/2019/7898914

Article  CAS  PubMed  PubMed Central  Google Scholar 

Khan YH, Qasim S, Uttra AM, Alotaibi NH, Alanazi AS, Alzarea AI et al (2023) Enalapril attenuated CFA provoked arthritic manifestation by modulating proinflammatory and anti-inflammatory cytokine network. Life Sci 324:121742

Article  CAS  PubMed  Google Scholar 

Kim W, Park S, Choi C, Kim YR, Park I, Seo C, et al (2016) Evaluation of anti-inflammatory potential of the new ganghwaljetongyeum on adjuvant-induced inflammatory arthritis in rats. Evid Based Complem Alternat Med 2016

Krieger E, Vriend G (2014) YASARA View—molecular graphics for all devices—from smartphones to workstations. Bioinformatics 30(20):2981–2982

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lee H-J, Kim K-W (2012) Anti-inflammatory effects of Arbutin in lipopolysaccharide-stimulated BV2 microglial cells. Inflamm Res 61:817–825

Article  CAS  PubMed  Google Scholar 

Lin N-Y, Beyer C, Gießl A, Kireva T, Scholtysek C, Uderhardt S et al (2013) Autophagy regulates TNFα-mediated joint destruction in experimental arthritis. Ann Rheum Dis 72(5):761–768

Article  CAS  PubMed  Google Scholar 

Lin Y-J, Anzaghe M, Schülke S (2020) Update on the pathomechanism, diagnosis, and treatment options for rheumatoid arthritis. Cells 9(4):880

Article  CAS  PubMed  PubMed Central  Google Scholar 

Liu X, Zou Q, Zeng B, Fang Y, Wei H (2013) Analysis of fecal Lactobacillus community structure in patients with early rheumatoid arthritis. Curr Microbiol 67:170–176

Article  CAS  PubMed  Google Scholar 

McInnes IB, Schett G (2007) Cytokines in the pathogenesis of rheumatoid arthritis. Nat Rev Immunol 7(6):429–442

Article  CAS  PubMed  Google Scholar 

Mima T, Nishimoto NJCoir (2009) Clinical value of blocking IL-6 receptor. 21(3):224–230

Naseem Z, Zahid M, Hanif MA, Shahid M (2020) Environmentally friendly extraction of bioactive compounds from Mentha arvensis using deep eutectic solvent as green extraction media. Pol J Environ Stud 29(5):3749–3757

Article  CAS  Google Scholar 

Nawaz S, Irfan HM, Akram M, Jahan S (2023) Linalool: Monoterpene alcohol effectiveness in chronic synovitis through lowering Interleukin-17, spleen and thymus indices. Int Immunopharmacol 121:110517

Article  CAS  PubMed  Google Scholar 

Nich C, Goodman SB (2014) Role of macrophages in the biological reaction to wear debris from joint replacements. J Long-term Effects Med Implants 24(4)

Prakash Babu N, Saravanan S, Pandikumar P, Bala Krishna K, Karunai Raj M, Ignacimuthu S (2014) Anti-inflammatory and anti-arthritic effects of 3-hydroxy, 2-methoxy sodium butanoate from the leaves of Clerodendrum phlomidis Lf. Inflamm Res 63:127–138

Article  CAS  PubMed  Google Scholar 

Qasim S, Alamgeer, Kalsoom S, Shahzad M, Bukhari IA, Vohra F et al (2021) Rosuvastatin attenuates rheumatoid arthritis-associated manifestations via modulation of the pro-and anti-inflammatory cytokine network: a combination of in vitro and in vivo studies. ACS Omega 6(3):2074–2084

Article  CAS  PubMed  PubMed Central  Google Scholar 

Qasim S, Khan YH, Uttra AM, Alotaibi NH, Alanazi AS, Alzarea AI, et al (2023) Appraisal of anti-inflammatory and immunomodulatory potential of ramipril against Freund’s adjuvant-provoked arthritic rat model. 1–11

Radu A-F, Bungau SG (2021) Management of rheumatoid arthritis: an overview. Cells 10(11):2857

Article  CAS  PubMed  PubMed Central  Google Scholar 

Razi E, Ehteram H, Akbari H, Chavoshi V, Razi A (2012) Evaluation of high-sensitivity C-reactive protein in acute asthma. Tanaffos 11(1):32

CAS  PubMed  PubMed Central  Google Scholar 

Ren X, Zhang M, Chen L, Zhang W, Huang Y, Luo H et al (2017) The anti-inflammatory effects of Yunnan Baiyao are involved in regulation of the phospholipase A2/arachidonic acid metabolites pathways in acute inflammation rat model. Mol Med Rep 16(4):4045–4053

Article  CAS  PubMed  PubMed Central  Google Scholar 

Saleem A, Saleem M, Akhtar MF, Shahzad M, Jahan S (2020) Polystichum braunii extracts inhibit complete Freund’s adjuvant-induced arthritis via upregulation of I-κB, IL-4, and IL-10, downregulation of COX-2, PGE2, IL-1β, IL-6, NF-κB, and TNF-α, and subsiding oxidative stress. Inflammopharmacology 28:1633–1648

Article  CAS  PubMed  Google Scholar 

Saleem M, Iftikhar A, Asif M, Hussain K, Alamgeer S, Shah PA et al (2021) Asphodelus tenuifolius extracts arrested inflammation and arthritis through modulation of TNF-α, NF-κB, ILs, and COX-2 activities in in vivo models. Inflammopharmacology 29:483–497

Article  CAS  PubMed  Google Scholar 

Schinocca C, Rizzo C, Fasano S, Grasso G, La Barbera L, Ciccia F, et al (2021) Role of the IL-23/IL-17 pathway in rheumatic diseases: an overview. 12, 637829

Sghaier MB, Skandrani I, Nasr N, Franca M-GD, Chekir-Ghedira L, Ghedira K (2011) Flavonoids and sesquiterpenes from Tecurium ramosissimum promote antiproliferation of human cancer cells and enhance antioxidant activity: a structure–activity relationship study. Environ Toxicol Pharmacol 32(3):336–348

Article  PubMed 

留言 (0)

沒有登入
gif