Hartnett ME, Penn JS (2012) Mechanisms and management of retinopathy of prematurity. N Engl J Med 367(26):2515–2526

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hartnett ME (2015) Pathophysiology and mechanisms of severe retinopathy of prematurity. Ophthalmology 122(1):200–210

Article  PubMed  Google Scholar 

Solebo AL, Teoh L, Rahi J (2017) Epidemiology of blindness in children. Arch Dis Child 102(9):853–857

Article  PubMed  Google Scholar 

Bourne RR, Stevens GA, White RA, Smith JL, Flaxman SR, Price H et al (2013) Causes of vision loss worldwide, 1990–2010: a systematic analysis. Lancet Glob Health 1(6):e339–e349

Article  PubMed  Google Scholar 

Chawanpaiboon S, Vogel JP, Moller AB, Lumbiganon P, Petzold M, Hogan D et al (2019) Global, regional, and national estimates of levels of preterm birth in 2014: a systematic review and modelling analysis. Lancet Glob Health 7(1):e37–e46

Article  PubMed  Google Scholar 

Tsiropoulos GN, Seliniotaki AK, Haidich AB, Ziakas N, Mataftsi A (2023) Comparison of adverse events between intravitreal anti-VEGF and laser photocoagulation for treatment-requiring retinopathy of prematurity: a systematic review. Int Ophthalmol 43(3):1027–1062

Article  PubMed  Google Scholar 

Hartnett ME, Stahl A (2023) Laser versus Anti-VEGF: A Paradigm shift for treatment-warranted retinopathy of prematurity. Ophthalmol Ther 12(5):2241–2252

Article  PubMed  PubMed Central  Google Scholar 

Lepore D, Quinn GE, Molle F, Orazi L, Baldascino A, Ji MH et al (2018) Follow-up to age 4 years of treatment of type 1 retinopathy of prematurity intravitreal bevacizumab injection versus laser: fluorescein angiographic findings. Ophthalmology 125(2):218–226

Article  PubMed  Google Scholar 

McCloskey M, Wang H, Jiang Y, Smith GW, Strange J, Hartnett ME (2013) Anti-VEGF antibody leads to later atypical intravitreous neovascularization and activation of angiogenic pathways in a rat model of retinopathy of prematurity. Invest Ophthalmol Vis Sci 54(3):2020–2026

Article  PubMed  PubMed Central  Google Scholar 

Sabri K, Ells AL, Lee EY, Dutta S, Vinekar A (2022) Retinopathy of prematurity: a global perspective and recent developments. Pediatrics. https://doi.org/10.1542/peds.2021-053924

Article  PubMed  Google Scholar 

Chen HX, Cleck JN (2009) Adverse effects of anticancer agents that target the VEGF pathway. Nat Rev Clin Oncol 6(8):465–477

Article  CAS  PubMed  Google Scholar 

Hartnett ME, Penn JS (2013) Mechanisms and management of retinopathy of prematurity. N Engl J Med 368(12):1162–1163

CAS  PubMed  Google Scholar 

Fu X, Feng S, Qin H, Yan L, Zheng C, Yao K (2023) Microglia: The breakthrough to treat neovascularization and repair blood-retinal barrier in retinopathy. Front Mol Neurosci 16:1100254

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wang S, Ji LY, Li L, Li JM (2019) Oxidative stress, autophagy and pyroptosis in the neovascularization of oxygen-induced retinopathy in mice. Mol Med Rep 19(2):927–934

CAS  PubMed  Google Scholar 

Dai C, Xiao J, Wang C, Li W, Su G (2022) Neurovascular abnormalities in retinopathy of prematurity and emerging therapies. J Mol Med (Berl) 100(6):817–828

Article  CAS  PubMed  Google Scholar 

Liu J, Tsang JKW, Fung FKC, Chung SK, Fu Z, Lo ACY (2022) Retinal microglia protect against vascular damage in a mouse model of retinopathy of prematurity. Front Pharmacol 13:945130

Article  CAS  PubMed  PubMed Central  Google Scholar 

Okin D, Kagan JC (2023) Inflammasomes as regulators of non-infectious disease. Semin Immunol 69:101815

Article  CAS  PubMed  Google Scholar 

Hotamisligil GS (2017) Inflammation, metaflammation and immunometabolic disorders. Nature 542(7640):177–185

Article  CAS  PubMed  Google Scholar 

Chen M, Rong R, Xia X (2022) Spotlight on pyroptosis: role in pathogenesis and therapeutic potential of ocular diseases. J Neuroinflammation 19(1):183

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bryan NB, Dorfleutner A, Kramer SJ, Yun C, Rojanasakul Y, Stehlik C (2010) Differential splicing of the apoptosis-associated speck like protein containing a caspase recruitment domain (ASC) regulates inflammasomes. J Inflamm (Lond) 7:23

Article  PubMed  Google Scholar 

Motani K, Kushiyama H, Imamura R, Kinoshita T, Nishiuchi T, Suda T (2011) Caspase-1 protein induces apoptosis-associated speck-like protein containing a caspase recruitment domain (ASC)-mediated necrosis independently of its catalytic activity. J Biol Chem 286(39):33963–33972

Article  CAS  PubMed  PubMed Central  Google Scholar 

Vasudevan SO, Behl B, Rathinam VA (2023) Pyroptosis-induced inflammation and tissue damage. Semin Immunol 69:101781

Article  CAS  PubMed  Google Scholar 

Dai Z, Liu WC, Chen XY, Wang X, Li JL, Zhang X (2023) Gasdermin D-mediated pyroptosis: mechanisms, diseases, and inhibitors. Front Immunol 14:1178662

Article  CAS  PubMed  PubMed Central  Google Scholar 

Broz P (2023) Unconventional protein secretion by gasdermin pores. Semin Immunol 69:101811

Article  CAS  PubMed  Google Scholar 

Sui A, Chen X, Shen J, Demetriades AM, Yao Y, Yao Y et al (2020) Inhibiting the NLRP3 inflammasome with MCC950 ameliorates retinal neovascularization and leakage by reversing the IL-1beta/IL-18 activation pattern in an oxygen-induced ischemic retinopathy mouse model. Cell Death Dis 11(10):901

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sonny S, Yuan H, Chen S, Duncan MR, Chen P, Benny M et al (2023) GSDMD deficiency ameliorates hyperoxia-induced BPD and ROP in neonatal mice. Sci Rep 13(1):143

Article  CAS  PubMed  PubMed Central  Google Scholar 

Desu HL, Plastini M, Illiano P, Bramlett HM, Dietrich WD, de Rivero Vaccari JP et al (2020) IC100: a novel anti-ASC monoclonal antibody improves functional outcomes in an animal model of multiple sclerosis. J Neuroinflammation 17(1):143

Article  CAS  PubMed  PubMed Central  Google Scholar 

Johnson NH, Kerr NA, de Rivero Vaccari JP, Bramlett HM, Keane RW, Dietrich WD (2023) Genetic predisposition to Alzheimer’s disease alters inflammasome activity after traumatic brain injury. Transl Res 257:66–77

Article  CAS  PubMed  Google Scholar 

Bae SP, Shin SH, Yoon YM, Kim EK, Kim HS (2021) Association of severe retinopathy of prematurity and bronchopulmonary dysplasia with adverse neurodevelopmental outcomes in preterm infants without severe brain injury. Brain Sci 11(6):699

Article  PubMed  PubMed Central  Google Scholar 

Dai C, Waduge P, Ji L, Huang C, He Y, Tian H et al (2022) Secretogranin III stringently regulates pathological but not physiological angiogenesis in oxygen-induced retinopathy. Cell Mol Life Sci 79(1):63

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chou TH, Toft-Nielsen J, Porciatti V (2019) Adaptation of retinal ganglion cell function during flickering light in the mouse. Sci Rep 9(1):18396

Article  CAS  PubMed  PubMed Central  Google Scholar 

Tzeng TC, Schattgen S, Monks B, Wang D, Cerny A, Latz E et al (2016) A fluorescent reporter mouse for inflammasome assembly demonstrates an important role for cell-bound and free ASC specks during in vivo infection. Cell Rep 16(2):571–582

Article  CAS  PubMed  PubMed Central  Google Scholar 

Franklin BS, Bossaller L, De Nardo D, Ratter JM, Stutz A, Engels G et al (2014) The adaptor ASC has extracellular and “prionoid” activities that propagate inflammation. Nat Immunol 15(8):727–737

Article  CAS  PubMed  PubMed Central  Google Scholar 

Smatlik N, Drexler SK, Burian M, Rocken M, Yazdi AS (2021) ASC speck formation after inflammasome activation in primary human keratinocytes. Oxid Med Cell Longev 2021:7914829

Article  PubMed  PubMed Central  Google Scholar 

Stutz A, Horvath GL, Monks BG, Latz E (2013) ASC speck formation as a readout for inflammasome activation. Methods Mol Biol 1040:91–101

Article  CAS  PubMed  Google Scholar 

Challa NVD, Chen S, Yuan H, Duncan MR, Moreno WJ, Bramlett H et al (2023) GSDMD gene knockout alleviates hyperoxia-induced hippocampal brain injury in neonatal mice. J Neuroinflammation 20(1):205

Article  CAS