1 Department of Critical Care and Postgraduate Program in Translational Medicine, D’Or Institute for Research and Education, Rio de Janeiro, Brazil.

2 Department of Critical Care Medicine, Athena Health Network, São Paulo, Brazil.

3 Department of Critical and Intensive Care Medicine, Academic Hospital Fundación Santa Fe de Bogota, Bogota, Colombia.

4 Department of Research and Development, Epimed Solutions, Rio de Janeiro, Brazil.

Dr. Salluh is supported, in part, by individual research grants from Conselho Nacional de Desenvolvimento Científico e Tecnológico and Fundação Carlos Chagas Filho de Amparo à Pesquisa do Rio de Janeiro. The remaining authors have disclosed that they do not have any potential conflicts of interest.

Dr. Salluh is the founder of Epimed Monitor, an electronic healthcare system used to track ICU quality metrics.