In vitro anticancer activity of Hirudinaria manillensis methanolic extract and its validation using in silico molecular docking approach

Barhoi D, Upadhaya P, Barbhuiya SN, Giri A, Giri S. Aqueous extract of Moringa oleifera exhibit potential anticancer activity and can be used as a possible cancer therapeutic agent: a study involving in vitro and in vivo approach. J Am Coll Nutr. 2021;40:70–85. https://doi.org/10.1080/07315724.2020.1735572.

Article  CAS  PubMed  Google Scholar 

Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, et al. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2021;71:209–49.

Article  PubMed  Google Scholar 

Baskar R, Lee KA, Yeo R, Yeoh KW. Cancer and radiation therapy: current advances and future directions. Int J Med Sci. 2012;9:193–9.

Article  PubMed  PubMed Central  Google Scholar 

Alaama M, Abdualkader AM, Ghawi AM, Merzouk A, Khalid RS, Helaluddin ABM. Assessment of trace heavy metals contamination in the tissues and saliva of the medicinal leech Hirudinaria manillensis. Turk J Fish Aquat Sci. 2021;21:225–31.

Article  Google Scholar 

Kvist S, Sarkar IN, Siddall ME. Genome-wide search for leech antiplatelet proteins in the non-blood-feeding leech Helobdella robusta (Rhyncobdellida: Glossiphoniidae) reveals evidence of secreted anticoagulants. Invertebr Biol. 2011;130:344–50.

Article  Google Scholar 

Merzouk A. Anticancer effects of medical Malaysian leech saliva extract (LSE). Pharm Anal Acta. 2012;s15:1–5.

Article  Google Scholar 

Jordan MA, Wilson L. Microtubules as a target for anticancer drugs. Nat Rev Cancer. 2004;4:253–65.

Article  CAS  PubMed  Google Scholar 

Rieder CL, Palazzo RE. Colcemid and the mitotic cycle. J Cell Sci. 1992;102:387–92.

Article  CAS  PubMed  Google Scholar 

Xu H, Yu Y, Marciniak D, Rishi AK, Sarkar FH, Kucuk O, et al. Epidermal growth factor receptor (EGFR)-related protein inhibits multiple members of the EGFR family in colon and breast cancer cells. Mol Cancer Ther. 2005;4:435–42.

Article  CAS  PubMed  Google Scholar 

Tessema Desta G, Andargie Ferede Y, Sisay Zewdu W, Adela Alemu M. Evaluation of antidiarrheal activity of 80% methanol extract and solvent fractions of the leaves of Withania somnifera (L.) Dunal in Swiss Albino mice. Evid Based Complement Altern Med. 2022;2022:7968973.

Article  Google Scholar 

Khalil EA, Swelim H, El-Tantawi H, Bakr AF, Abdellatif A. Characterization, cytotoxicity and antioxidant activity of sea urchins (Diadema savignyi) and jellyfish (Aurelia aurita) extracts. Egypt J Aquat Res. 2022;48:343–8. https://doi.org/10.1016/j.ejar.2022.05.005.

Article  Google Scholar 

Mitra I, Mukherjee S, Reddy Venkata PB, Dasgupta S, Jagadeesh Bose CK, Mukherjee S, et al. Benzimidazole based Pt(II) complexes with better normal cell viability than cisplatin: synthesis, substitution behavior, cytotoxicity, DNA binding and DFT study. RSC Adv. 2016;6:76600–13.

Article  ADS  CAS  Google Scholar 

Sahu N, Mishra S, Kesheri M, Kanchan S, Sinha RP. Identification of cyanobacteria-based natural inhibitors against SARS-CoV-2 druggable target ACE2 using molecular docking study, ADME and toxicity analysis. Indian J Clin Biochem. 2023;38:361–73. https://doi.org/10.1007/s12291-022-01056-6.

Article  CAS  PubMed  Google Scholar 

Nair DG, Weiskirchen R, Al-Musharafi SK. The use of marine-derived bioactive compounds as potential hepatoprotective agents. Acta Pharmacol Sin. 2015;36:158–70.

Article  CAS  PubMed  Google Scholar 

Amin HB, Amer A, Azzam M, Abd El-Sattar NEA, Mahmoud D, Al-Ashaal S, et al. Antimicrobial and anticancer activities of Periplaneta americana tissue lysate: an in vitro study. J King Saud Univ Sci. 2022;34:102095. https://doi.org/10.1016/j.jksus.2022.102095.

Article  Google Scholar 

Kamran S, Sinniah A, Abdulghani MAM, Alshawsh MA. Therapeutic potential of certain terpenoids as anticancer agents: a scoping review. Cancers (Basel). 2022;14(5):1100.

Article  CAS  PubMed  Google Scholar 

Sutton M. Superior mediastinal obstruction treated with demecolcine followed by radiotherapy. Br Med J. 1965;1:495.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Shakouri A, Adljouy N, Abdolalizadeh J. Anti-cancer activity of liposomal medical leech saliva extract (LSE). In: World congress on recent advances in nanotechnology, 2018, pp. 18–21.

Omalu I, Egwim E, Mgbemena C, Eke S, Ubanwa D, Busari M, et al. Free radical scavenging activity of the Nigerian leech (Aliolimnatis michaelseni) saliva extract. Br J Pharm Res. 2015;8:1–6.

Article  Google Scholar 

Kumar BS, Prasad ARG, Reddy PR, Ravindranath LK. Synthesis, antimicrobial and in silico EGFR inhibitory activity evaluation of sulfonylamino pyrrolidine derivatives. Pharm Chem J. 2016;50:443–50.

Article  CAS  Google Scholar 

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