Therapeutic HPV Vaccination: A Strategy for Cervical Cancer Elimination in India

Wang R, Pan W, Jin L, Huang W, Li Y, Wu D, et al. Human papillomavirus vaccine against cervical cancer: opportunity and challenge. Cancer Lett. 2020;471:88–102.

Article  CAS  PubMed  ADS  Google Scholar 

History does repeat: pandemic vaccine uproar is nothing new [Internet]. [cited 2022 Oct 25]. Available from: https://www.webmd.com/vaccines/covid-19-vaccine/news/20211014/vaccine-opposition-not-new

UICC. GLOBOCAN 2020: New global cancer data. UICC. 2018;6–11.

Cervical cancer [Internet]. [cited 2022 Sep 19]. Available from: https://www.who.int/news-room/fact-sheets/detail/cervical-cancer

Arbyn M, Weiderpass E, Bruni L, de Sanjosé S, Saraiya M, Ferlay J, et al. Estimates of incidence and mortality of cervical cancer in 2018: a worldwide analysis. Lancet Glob Health. 2020;8(2):e191-203.

Article  PubMed  Google Scholar 

Cervical cancer elimination initiative [Internet]. [cited 2022 Sep 15]. Available from: https://www.who.int/initiatives/cervical-cancer-elimination-initiative

Bruni L, Saura-Lázaro A, Montoliu A, Brotons M, Alemany L, Diallo MS, et al. HPV vaccination introduction worldwide and WHO and UNICEF estimates of national HPV immunization coverage 2010–2019. Prev Med (Baltim). 2021;144:106399.

Article  Google Scholar 

Bruni L, Saura-Lázaro A, Montoliu A, Brotons M, Alemany L, Diallo MS, et al. HPV vaccination introduction worldwide and WHO and UNICEF estimates of national HPV immunization coverage 2010–2019. Prev Med (Baltim). 2021;144.

Adolescent Health : National health mission [Internet]. [cited 2022 Dec 30]. Available from: https://nhm.gov.in/index1.php?lang=1&level=2&sublinkid=818&lid=221

Chabeda A, Yanez RJR, Lamprecht R, Meyers AE, Rybicki EP, Hitzeroth II. Therapeutic vaccines for high-risk HPV-associated diseases. Papillomavirus Res. 2018;5:46.

Article  PubMed  Google Scholar 

Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, et al. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2021;71(3):209–49.

Article  PubMed  Google Scholar 

Prudden HJ, Achilles SL, Schocken C, Broutet N, Canfell K, Akaba H, et al. Understanding the public health value and defining preferred product characteristics for therapeutic human papillomavirus (HPV) vaccines: World Health Organization consultations, October 2021–March 2022. Vaccine. 2022;40(41):5843–55.

Article  PubMed  Google Scholar 

Singh M, Jha RP, Shri N, Bhattacharyya K, Patel P, Dhamnetiya D. Secular trends in incidence and mortality of cervical cancer in India and its states, 1990–2019: data from the Global Burden of Disease 2019 Study. BMC Cancer. 2022;22(1):1–12.

Article  Google Scholar 

Sankaranarayanan R, Esmy PO, Rajkumar R, Muwonge R, Swaminathan R, Shanthakumari S, et al. Effect of visual screening on cervical cancer incidence and mortality in Tamil Nadu, India: a cluster-randomised trial. Lancet. 2007;370(9585):398–406.

Article  PubMed  Google Scholar 

Lin S, Gao K, Gu S, You L, Qian S, Tang M, et al. Worldwide trends in cervical cancer incidence and mortality, with predictions for the next 15 years. Cancer. 2021;127(21):4030–9.

Article  PubMed  Google Scholar 

Yang M, Du J, Lu H, Xiang F, Mei H, Xiao H, et al. Global trends and age-specific incidence and mortality of cervical cancer from 1990 to 2019: an international comparative study based on the Global Burden of Disease. BMJ Open. 2022;12:55470.

Article  Google Scholar 

Soerjomataram I, Bray F. Planning for tomorrow: global cancer incidence and the role of prevention 2020–2070. Nat Rev Clin Oncol 2021. 2021;18(10):663–72.

Article  Google Scholar 

Burden of cervical cancer and role of screening in India. 2016

Ratnasamy P, Chagpar AB. HPV vaccination and factors influencing vaccine uptake among people of Indian ancestry living in the United States. Epidemiol Infect. 2022;150:1–5.

Article  PubMed  PubMed Central  Google Scholar 

Zhang X, Zeng Q, Cai W, Ruan W. Trends of cervical cancer at global, regional, and national level: data from the Global Burden of Disease study 2019. BMC Pub Health. 2021;21(1):1–10.

Google Scholar 

VizHub—GBD India Compare [Internet]. [cited 2023 Dec 1]. Available from: https://vizhub.healthdata.org/gbd-compare/india

McGraw SL, Ferrante JM. Update on prevention and screening of cervical cancer. World J Clin Oncol. 2014;5(4):744–52.

Article  PubMed  PubMed Central  Google Scholar 

Agustiansyah P, Rizal Sanif, Siti Nurmaini, Irfannuddin, Legiran. Epidemiology and risk factors for cervical cancer. Biosci Med J Biomed Transl Res. 2021;5(7):624–31.

Human Papilloma Virus ICMR: High power committee to evaluate performance of ICMR 2012–2013. Disease Specific Documents for XII Plan.

Eng -L Ing K, Allin W, Ord T, Ngström Å, Tendahl LS, Öran G, et al. Type-specific persistence of human papillomavirus DNA before the development of invasive cervical cancer a bstract Background Infection with the human papilloma. 1999;341:1633.

Gius D, Funk MC, Chuang EY, Feng S, Huettner PC, Nguyen L, et al. Profiling microdissected epithelium and stroma to model genomic signatures for cervical carcinogenesis accommodating for covariates. Cancer Res. 2007;67(15):7113–23.

Article  CAS  PubMed  Google Scholar 

Alrajjal A, Pansare V, Choudhury MSR, Khan MYA, Shidham VB. Squamous intraepithelial lesions (SIL: LSIL, HSIL, ASCUS, ASC-H, LSIL-H) of Uterine Cervix and Bethesda System. Cytojournal. 2021;18.

Zielinski GD, Snijders PJF, Rozendaal L, Voorhorst FJ, Van Der Linden HC, Runsink AP, et al. HPV presence precedes abnormal cytology in women developing cervical cancer and signals false negative smears. Br J Cancer. 2001;85(3):398–404.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Holowaty P, Miller AB, Rohan T, To T. Natural history of dysplasia of the uterine cervix. J Natl Cancer Inst. 1999;91(3):252–8.

Article  CAS  PubMed  Google Scholar 

Siddharthar J, Rajkumar B, Deivasigamani K. Knowledge awareness and prevention of cervical cancer among women attending a tertiary care hospital in Puducherry, India. J Clin Diagn Res. 2014;8(6):8–10.

Google Scholar 

Lam JUH, Rebolj M, Dugué PA, Bonde J, von Euler-Chelpin M, Lynge E. Condom use in prevention of Human Papillomavirus infections and cervical neoplasia: systematic review of longitudinal studies. J Med Screen. 2014;21(1):38–50.

Article  PubMed  Google Scholar 

National Family Health Survey (NFHS-5) [Internet]. [cited 2022 Oct 27]. Available from: http://rchiips.org/nfhs/factsheet_NFHS-5.shtml

Asian Pacific Journal of Cancer Prevention [Internet]. [cited 2022 Nov 8]. Available from: http://journal.waocp.org/?sid=Entrez:PubMed&id=pmid:17250453&key=2006.7.4.683

Pimple S, Mishra G, Shastri S. Global strategies for cervical cancer prevention. Curr Opin Obstet Gynecol [Internet]. 2016 [cited 2022 Nov 8]:28(1):4–10. Available from: https://pubmed.ncbi.nlm.nih.gov/26642063/

Bruni L, Serrano B, Roura E, Alemany L, Cowan M, Herrero R, et al. Cervical cancer screening programmes and age-specific coverage estimates for 202 countries and territories worldwide: a review and synthetic analysis. Lancet Glob Health. 2022;10(8):e1115–27.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Dabash R, Vajpayee J, Jacob M, Dzuba I, Lal N, Bradley J, et al. A strategic assessment of cervical cancer prevention and treatment services in 3 districts of Uttar Pradesh, India. 2005.

Marlow LAV, Wardle J, Forster AS, Waller J. Ethnic differences in human papillomavirus awareness and vaccine acceptability. J Epidemiol Community Health(1978). 2009;63(12):1010.

Article  CAS  Google Scholar 

Nour NM. Cervical cancer: a preventable death. Rev Obstet Gynecol. 2009;2(4):240–4.

PubMed  PubMed Central  Google Scholar 

Sankaranarayanan R, Basu P, Kaur P, Bhaskar R, Singh GB, Denzongpa P, et al. Current status of human papillomavirus vaccination in India’s cervical cancer prevention efforts. Lancet Oncol. 2019;20(11):e637–44.

Article  PubMed  Google Scholar 

Explained: What India’s first HPV vaccine could mean for fight against cervical cancer | Explained news,The Indian Express [Internet]. [cited 2022 Sep 16]. Available from: https://indianexpress.com/article/explained/what-indias-first-hpv-vaccine-could-mean-for-fight-against-cervical-cancer-8027690/

Government of India Ministry of Health and Family Welfare Immunization Division N i r m a n B h a w a n.

WHO guidelines WHO guidelines for screening and treatment of precancerous lesions for cervical cancer prevention.

Roy S, Shankar A. HPV vaccination of girl child in India: intervention for primary prevention of cervical cancer. Asian Pac J Cancer Prev. 2018;19(9):2357.

PubMed  PubMed Central  Google Scholar 

Holroyd TA, Yan SD, Srivastava V, Srivastava A, Wahl B, Morgan C, et al. Designing a pro-equity HPV vaccine delivery program for girls who have dropped out of school: community perspectives from Uttar Pradesh. India: Health Promot Pract; 2021.

Google Scholar 

National and state vaccination coverage among adolescents aged 13–17 years—United States, 2011—PubMed [Internet]. [cited 2022 Dec 13]. Available from: https://pubmed.ncbi.nlm.nih.gov/22932301/

Opel DJ, Heritage J, Taylor JA, Mangione-Smith R, Salas HS, DeVere V, et al. The Architecture of provider-Parent vaccine discussions at health supervision visits. Pediatrics. 2013;132(6):1037–46.

Article  PubMed  PubMed Central  Google Scholar 

Kataria I, Siddiqui M, Treiman K, Foley S, Anand M, Biswas S, et al. Awareness, perceptions, and choices of physicians pertaining to human papillomavirus (HPV) vaccination in India: a formative research study. Vaccine X. 2022;12: 100228.

Article  PubMed  PubMed Central  Google Scholar 

Gilkey MB, Malo TL, Shah PD, Hall ME, Brewer NT. Quality of physician communication about human papillomavirus vaccine: findings from a national survey. Cancer Epidemiol Biomark Prev. 2015;24(11):1673.

Article  Google Scholar 

Karafillakis E, Dinca I, Apfel F, Cecconi S, Würz A, Takacs J, et al. Vaccine hesitancy among healthcare workers and their patients in Europe. 2016.

Thulaseedharan J, Frie K, Sankaranarayanan R. Challenges of health promotion and education strategies to prevent cervical cancer in India: a systematic review. J Educ Health Promot. 2019;8(1).

Shah P, Shetty V, Ganesh M, Shetty AK. Challenges to human papillomavirus vaccine acceptability among women in South India: an exploratory study. Am J Trop Med Hyg. 2021;105(4):966–73.

Article  PubMed  PubMed Central  Google Scholar 

Bingham A, Drake JK, LaMontagne DS. Sociocultural issues in the introduction of human papillomavirus vaccine in low-resource settings. Arch Pediatr Adolesc Med. 2009;163(5):455–61.

Article  PubMed  Google Scholar 

Hussain S, Bharadwaj M, Nasare V, Kumari M, Sharma S, Hedau S, et al. Human papillomavirus infection among young adolescents in India: impact of vaccination. J Med Virol. 2012;84(2):298–305.

Article  PubMed  Google Scholar 

Larson HJ, Brocard P, Garnett G. The India HPV-vaccine suspension. Lancet. 2010;376(9741):572–3.

Article  PubMed  Google Scholar 

Vorsters A, Arbyn M, Baay M, Bosch X, de Sanjosé S, Hanley S, et al. Overcoming barriers in HPV vaccination and screening programs. Papillomavirus Res. 2017;4:45.

Article  PubMed  PubMed Central  Google Scholar 

Wong LP, Wong PF, Megat Hashim MMAA, Han L, Lin Y, Hu Z, et al. Multidimensional social and cultural norms influencing HPV vaccine hesitancy in Asia. Hum Vaccin Immunother. 2020;16(7):1611.

Article  PubMed  PubMed Central 

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