Identifying a target group for selenium supplementation in high-risk cardiac surgery: a secondary analysis of the SUSTAIN CSX trial

Laffey JG, Boylan JF, Cheng DC (2002) The systemic inflammatory response to cardiac surgery: implications for the anesthesiologist. Anesthesiology 97:215–252

Article  CAS  PubMed  Google Scholar 

Squiccimarro E, Stasi A, Lorusso R, Paparella D (2022) Narrative review of the systemic inflammatory reaction to cardiac surgery and cardiopulmonary bypass. Artif Organs 46:568–577

Article  PubMed  PubMed Central  Google Scholar 

Corral-Velez V, Lopez-Delgado JC, Betancur-Zambrano NL, Lopez-Suñe N, Rojas-Lora M, Torrado H, Ballus J (2015) The inflammatory response in cardiac surgery: an overview of the pathophysiology and clinical implications. Inflamm Allergy Drug Targets 13:367–370

Article  PubMed  Google Scholar 

Motoyama T, Okamoto K, Kukita I, Hamaguchi M, Kinoshita Y, Ogawa H (2003) Possible role of increased oxidant stress in multiple organ failure after systemic inflammatory response syndrome. Crit Care Med 31:1048–1052

Article  CAS  PubMed  Google Scholar 

Avery JC, Hoffmann PR (2018) Selenium, selenoproteins, and immunity. Nutrients 10:1203

Article  PubMed  PubMed Central  Google Scholar 

Hariharan S, Dharmaraj S (2020) Selenium and selenoproteins: it’s role in regulation of inflammation. Inflammopharmacology 28:667–695

Article  CAS  PubMed  PubMed Central  Google Scholar 

Rayman MP (2012) Selenium and human health. Lancet (London, England) 379:1256–1268

Article  CAS  PubMed  Google Scholar 

Stoppe C, Schälte G, Rossaint R, Coburn M, Graf B, Spillner J, Marx G, Rex S (2011) The intraoperative decrease of selenium is associated with the postoperative development of multiorgan dysfunction in cardiac surgical patients. Crit Care Med 39:1879–1885

Article  CAS  PubMed  Google Scholar 

Stoppe C, Spillner J, Rossaint R, Coburn M, Schälte G, Wildenhues A, Marx G, Rex S (2013) Selenium blood concentrations in patients undergoing elective cardiac surgery and receiving perioperative sodium selenite. Nutrition 29:158–165

Article  CAS  PubMed  Google Scholar 

Stoppe C, McDonald B, Meybohm P, Christopher KB, Fremes S, Whitlock R, Mohammadi S, Kalavrouziotis D, Elke G, Rossaint R, Helmer P, Zacharowski K, Günther U, Parotto M, Niemann B, Böning A, Mazer CD, Jones PM, Ferner M, Lamarche Y, Lamontagne F, Liakopoulos OJ, Cameron M, Müller M, Zarbock A, Wittmann M, Goetzenich A, Kilger E, Schomburg L, Day AG, Heyland DK (2023) Effect of high-dose selenium on postoperative organ dysfunction and mortality in cardiac surgery patients: the SUSTAIN CSX randomized clinical trial. JAMA Surg 158:235

Article  PubMed  PubMed Central  Google Scholar 

Manzanares W, Langlois PL, Heyland DK (2015) Pharmaconutrition with selenium in critically ill patients: what do we know? Nutr Clin Pract 30:34–43

Article  PubMed  Google Scholar 

Stevanovic A, Coburn M, Menon A, Rossaint R, Heyland D, Schälte G, Werker T, Wonisch W, Kiehntopf M, Goetzenich A, Rex S, Stoppe C (2014) The importance of intraoperative selenium blood levels on organ dysfunction in patients undergoing off-pump cardiac surgery: a randomised controlled trial. PLoS ONE 9:e104222

Article  PubMed  PubMed Central  Google Scholar 

Pei J, Pan X, Wei G, Hua Y (2023) Research progress of glutathione peroxidase family (GPX) in redoxidation. Front Pharmacol 14:1147414

Article  CAS  PubMed  PubMed Central  Google Scholar 

Stoppe C, McDonald B, Rex S, Manzanares W, Whitlock R, Fremes S, Fowler R, Lamarche Y, Meybohm P, Haberthür C, Rossaint R, Goetzenich A, Elke G, Day A, Heyland DK (2014) SodiUm SeleniTe Administration IN Cardiac Surgery (SUSTAIN CSX-trial): study design of an international multicenter randomized double-blinded controlled trial of high dose sodium-selenite administration in high-risk cardiac surgical patients. Trials 15:339

Article  PubMed  PubMed Central  Google Scholar 

Bierl C, Voetsch B, Jin RC, Handy DE, Loscalzo J (2004) Determinants of human plasma glutathione peroxidase (GPx-3) expression. J Biol Chem 279:26839–26845

Article  CAS  PubMed  Google Scholar 

Artunc F, Schleicher E, Weigert C, Fritsche A, Stefan N, Häring HU (2016) The impact of insulin resistance on the kidney and vasculature. Nat Rev Nephrol 12:721–737

Article  CAS  PubMed  Google Scholar 

Demircan K, Bengtsson Y, Sun Q, Brange A, Vallon-Christersson J, Rijntjes E, Malmberg M, Saal LH, Rydén L, Borg Å, Manjer J, Schomburg L (2021) Serum selenium, selenoprotein P and glutathione peroxidase 3 as predictors of mortality and recurrence following breast cancer diagnosis: a multicentre cohort study. Redox Biol 47:102145

Article  CAS  PubMed  PubMed Central  Google Scholar 

Demircan K, Chillon TS, Bracken T, Bulgarelli I, Campi I, Du Laing G, Fafi-Kremer S, Fugazzola L, Garcia AA, Heller R, Hughes DJ, Ide L, Klingenberg GJ, Komarnicki P, Krasinski Z, Lescure A, Mallon P, Moghaddam A, Persani L, Petrovic M, Ruchala M, Solis M, Vandekerckhove L, Schomburg L (2022) Association of COVID-19 mortality with serum selenium, zinc and copper: six observational studies across Europe. Front Immunol 13:1022673

Article  CAS  PubMed  PubMed Central  Google Scholar 

Moghaddam A, Heller RA, Sun Q, Seelig J, Cherkezov A, Seibert L, Hackler J, Seemann P, Diegmann J, Pilz M, Bachmann M, Minich WB, Schomburg L (2020) Selenium deficiency is associated with mortality risk from COVID-19. Nutrients 12:2098

Article  CAS  PubMed  PubMed Central  Google Scholar 

Heller RA, Sun Q, Hackler J, Seelig J, Seibert L, Cherkezov A, Minich WB, Seemann P, Diegmann J, Pilz M, Bachmann M, Ranjbar A, Moghaddam A, Schomburg L (2021) Prediction of survival odds in COVID-19 by zinc, age and selenoprotein P as composite biomarker. Redox Biol 38:101764

Article  CAS  PubMed  Google Scholar 

Flohé L, Günzler WA (1984) Assays of glutathione peroxidase. Methods Enzymol 105:114–121

Article  PubMed  Google Scholar 

Bomer N, Grote Beverborg N, Hoes MF, Streng KW, Vermeer M, Dokter MM, IJmker J, Anker SD, Cleland JGF, Hillege HL, Lang CC, Ng LL, Samani NJ, Tromp J, van Veldhuisen DJ, Touw DJ, Voors AA, van der Meer P (2020) Selenium and outcome in heart failure. Eur J Heart Fail 22:1415–1423

Article  CAS  PubMed  Google Scholar 

Du Laing G, Petrovic M, Lachat C, De Boevre M, Klingenberg GJ, Sun Q, De Saeger S, De Clercq J, Ide L, Vandekerckhove L, Schomburg L (2021) Course and survival of COVID-19 patients with comorbidities in relation to the trace element status at hospital admission. Nutrients 13:3304

Article  PubMed  PubMed Central  Google Scholar 

Olson GE, Winfrey VP, Hill KE, Burk RF (2008) Megalin mediates selenoprotein P uptake by kidney proximal tubule epithelial cells. J Biol Chem 283:6854–6860

Article  CAS  PubMed  Google Scholar 

Chiu-Ugalde J, Theilig F, Behrends T, Drebes J, Sieland C, Subbarayal P, Köhrle J, Hammes A, Schomburg L, Schweizer U (2010) Mutation of megalin leads to urinary loss of selenoprotein P and selenium deficiency in serum, liver, kidneys and brain. Biochem J 431:103–111

Article  CAS  PubMed  Google Scholar 

Frass OM, Bühling F, Täger M, Frass H, Ansorge S, Huth C, Welte T (2001) Antioxidant and antiprotease status in peripheral blood and BAL fluid after cardiopulmonary bypass. Chest 120:1599–1608

Article  CAS  PubMed  Google Scholar 

Zou Z, Ren T, Li Y, Zeng Q, Wang X, Teng J, Xu J, Jia P, Ding X (2023) The association between serum glutathione peroxidase-3 concentration and risk of acute kidney injury after cardiac surgery: a nested case–control study. Am J Cardiol 209:29–35

Article  CAS  PubMed  Google Scholar 

Hall JE, do Carmo JM, da Silva AA, Wang Z, Hall ME (2019) Obesity, kidney dysfunction and hypertension: mechanistic links. Nat Rev Nephrol 15:367–385

Article  PubMed  PubMed Central  Google Scholar 

Manzanares W, Biestro A, Galusso F, Torre MH, Mañay N, Pittini G, Facchin G, Hardy G (2009) Serum selenium and glutathione peroxidase-3 activity: biomarkers of systemic inflammation in the critically ill? Intensive Care Med 35:882–889

Article  CAS  PubMed  Google Scholar 

Allingstrup M, Afshari A (2015) Selenium supplementation for critically ill adults. Cochrane Database Syst Rev 2015:003703

Google Scholar 

Forceville X, Vitoux D, Gauzit R, Combes A, Lahilaire P, Chappuis P (1998) Selenium, systemic immune response syndrome, sepsis, and outcome in critically ill patients. Crit Care Med 26:1536–1544

Article  CAS  PubMed  Google Scholar 

Landucci F, Mancinelli P, De Gaudio AR, Virgili G (2014) Selenium supplementation in critically ill patients: a systematic review and meta-analysis. J Crit Care 29:150–156

Article  CAS  PubMed  Google Scholar 

Mahmoodpoor A, Hamishehkar H, Shadvar K, Ostadi Z, Sanaie S, Saghaleini SH, Nader ND (2019) The effect of intravenous selenium on oxidative stress in critically ill patients with acute respiratory distress syndrome. Immunol Invest 48:147–159

Article  PubMed  Google Scholar 

Manzanares W, Langlois PL, Hardy G (2013) Update on antioxidant micronutrients in the critically ill. Curr Opin Clin Nutr Metab Care 16:719–725

Article  CAS 

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