Aebi H (1984) Catalase in vitro. Methods Enzymol 105:121–126. https://doi.org/10.1016/s0076-6879(84)05016-3

Article  CAS  PubMed  Google Scholar 

An JP, Ha TK, Kim J, Cho TO, Oh WK (2016) Protein tyrosine phosphatase 1B inhibitors from the stems of Akebia quinata. Molecules 21:1091. https://doi.org/10.3390/molecules21081091

Article  CAS  PubMed  PubMed Central  Google Scholar 

Arando A, Delgado JV, Fernández-Prior A, León JM, Bermúdez-Oria A, Nogales S, Pérez-Marin CC (2019) Effect of different olive oil-derived antioxidants (hydroxytyrosol and 3,4-dihydroxyphenylglycol) on the quality of frozen-thawed ram sperm. Cryobiology 86:33–39. https://doi.org/10.1016/j.cryobiol.2019.01.002

Article  CAS  PubMed  Google Scholar 

Arya VS, Kanthlal SK, Linda G (2020) The role of dietary polyphenols in inflammatory bowel Disease: a possible clue on the molecular mechanisms involved in the prevention of immune and inflammatory reactions. J Food Biochem 44:e13369. https://doi.org/10.1111/jfbc.13369

Article  CAS  PubMed  Google Scholar 

Chopra RN, Nayar SL, Chopra IC (1986) Glossary of Indian medicinal plants. Council of Scientific and Industrial Research, New Delhi

Google Scholar 

Chung J, Nguyen AK, Henstridge DC, Holmes AG, Chan MH, Mesa JL, Lancaster GI, Southgate RJ, Bruce CR, Duffy SJ, Horvath I, Mestril R, Watt MJ, Hooper PL, Kingwell BA, Vigh L, Hevener A, Febbraio MA (2008) HSP72 protects against obesity-induced insulin resistance. Proc Natl Acad Sci USA 105:1739–1744. https://doi.org/10.1073/pnas.0705799105

Article  PubMed  PubMed Central  Google Scholar 

Dani C, Bonatto D, Salvador M, Pereira MD, Henriques JA (2008) Eleutherio E. Antioxidant protection of resveratrol and catechin in Saccharomyces cerevisiae. J Agric Food Chem 56:4268–4272. https://doi.org/10.1021/jf800752s

Article  CAS  PubMed  Google Scholar 

Ellman GL (1959) Tissue sulfydryl groups. Arch Biochem Biophys 82:70–77. https://doi.org/10.1016/0003-9861(59)90090-6

Article  CAS  PubMed  Google Scholar 

Engin AB, Tsatsakis AM, Tsoukalas D, Engin A (2018) Do flavanols-rich natural products relieve obesity-related insulin resistance? Food Chem Toxicol 112:157–167. https://doi.org/10.1016/j.fct.2017.12.055

Article  CAS  PubMed  Google Scholar 

Ghosh C, Mallick C (2020) Protective effect of ethanolic extract of Hygrophila auriculata seeds in cyproterone acetate-induced sexual dysfunction in male albino rats. Andrologia 52:e13482. https://doi.org/10.1111/and.13482

Article  PubMed  Google Scholar 

Gupta DR, Bhushan R, Ahmad B (1983) Chemical examination of Asteracantha Longifolia. J Nat Prod 46:938. https://doi.org/10.1021/np50030a023

Article  CAS  Google Scholar 

Gupte AA, Bomhoff GL, Swerdlow RH, Geiger PC (2009) Heat treatment improves glucose tolerance and prevents skeletal muscle insulin resistance in rats fed a high-fat diet. Diabetes 58:567–578. https://doi.org/10.2337/db08-1070

Article  PubMed  PubMed Central  Google Scholar 

Hadrich F, Sayadi S (2018) Apigetrin inhibits adipogenesis in 3T3-L1 cells by downregulating PPARγ and CEBP-α. Lipids Health Dis 17:95. https://doi.org/10.1186/s12944-018-0738-0

Hoehn KL, STTBon AB, Hohnen-Behrens C, Turner N, Hoy AJ, Maghzal GJ, Stocker R, Van Remmen H, Kraegen EW, Cooney GJ, Richardson AR, James DE (2009) Insulin resistance is a cellular antioxidant defense mechanism. PNAS 106:17787–11792. https://doi.org/10.1073/pnas.0902380106

Article  PubMed  PubMed Central  Google Scholar 

Hurrle S, Hsu WH (2017) The etiology of oxidative stress in insulin resistance. Biomed J 40:257–262. https://doi.org/10.1016/j.bj.2017.06.007

Article  PubMed  PubMed Central  Google Scholar 

Igarashi K, Ohmuma M (1995) Effects of isorhamnetin, rhamnetin, and quercetin on the concentrations of cholesterol and lipoperoxide in the serum and liver and on the blood and liver antioxidative enzyme activities of rats. Biosci Biotechnol Biochem 59:595–601. https://doi.org/10.1271/bbb.59.595

Article  CAS  PubMed  Google Scholar 

Ji SY, Choi KM, Lee YS, Yu JY, Shin DM, Lee S, Lee S, Yoo KS, Lee YM, Yun YP, Yoo HS (2012) Rhamnetin induced suppression of clonal expansion during early stage of adipogenesis. Arch Pharm Res 35:1083–1089. https://doi.org/10.1007/s12272-012-0616-7

Article  CAS  PubMed  Google Scholar 

Kim YJ (2013) Rhamnetin attenuates melanogenesis by suppressing oxidative stress and pro-inflammatory mediators. Biol Pharm Bull 36:1341–1347. https://doi.org/10.1248/bpb.b13-00276

Kumar S, Lakshmi PK, Sahi C, Pawar RS (2019) Sida cordifolia accelerates wound healing process delayed by dexamethasone in rats: effect on ROS and probable mechanism of action. J Ethnopharmacol 235:279–292. https://doi.org/10.1016/j.jep.2018.07.003

Article  CAS  PubMed  Google Scholar 

Lakshmi PK, Kumar S, Pawar S, Kuriakose BB, Sudheesh MS, Pawar RS (2020) Targeting metabolic syndrome with phytochemicals: focus on the role of molecular chaperones and hormesis in drug discovery. Pharmacol Res 159:104925. https://doi.org/10.1016/j.phrs.2020.104925

Article  CAS  PubMed  Google Scholar 

Lee YJ, Lee JH, Kim YH, Kim JH, Yu SY, Kim DB, Lee JS, Cho ML, Cho J-H, Kim BK, Lee B-Y, Lee O-H (2015) Assessment of the pectolinarin content and the radical scavenging-linked antiobesity activity of Cirsium setidens Nakai extracts. Food Sci Biotechnol 24:2235–2243. https://doi.org/10.1007/s10068-015-0298-2

Article  CAS  Google Scholar 

Liao Z, Chen X, Wu M (2010) Antidiabetic effect of flavones from Cirsium japonicum DC in diabetic rats. Arch Pharm Res 33:353–362, 353. https://doi.org/10.1007/s12272-010-0302-6

Lim HS, Kim OS, Kim BY, Jeong SJ (2016) Apigetrin from Scutellaria baicalensis Georgi inhibits neuroinflammation in BV-2 microglia and exerts neuroprotective effect in HT22 hippocampal cells. J Med Food 19:1032–1040. https://doi.org/10.1089/jmf.2016.0074

Article  CAS  PubMed  Google Scholar 

Literáti-Nagy B, Tory K, Peitl B, Bajza Á, Korányi L, Literáti-Nagy Z, Hooper PL, Vígh L, Szilvássy Z (2014) Improvement of insulin sensitivity by a novel drug candidate, BGP-15, in different animal studies. Metab Syndr Relat Disord 12:125–131. https://doi.org/10.1089/met.2013.0098

Article  CAS  PubMed  Google Scholar 

Lowry OH, Rosebrough NJ, Farr AL, Randall RI (1951) Protein measurement with the Folin phenol reagent. J Biol Chem 193:438–448

Article  Google Scholar 

Luo J, Liu J, Kong L (2008) New pentacyclic triterpenes from Gypsophila oldhamiana and their biological evaluation as glycogen phosphorylase inhibitors. Chem Biodivers 5:751–757. https://doi.org/10.1002/cbdv.200890071

Article  CAS  PubMed  Google Scholar 

Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC (1985) Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28:412–419. https://doi.org/10.1007/BF00280883

Article  CAS  PubMed  Google Scholar 

Mendes V, Vilaça R, de Freitas V, Ferreira PM, Mateus N, Costa V (2015) Effect of myricetin, pyrogallol, and phloroglucinol on yeast resistance to oxidative stress. Oxid Med Cell Longev 2015:782504. https://doi.org/10.1155/2015/782504

Article  PubMed  PubMed Central  Google Scholar 

Misra TN, Singh RS, Pandey HS, Singh BK, Pandey RP (2001) Constituents of Asteracantha Longifolia. Fitoterapia 72:194–196. https://doi.org/10.1016/S0367-326X(00)00269-0

Article  CAS  PubMed  Google Scholar 

Mukherjee A, Morales-scheihing D, Butler PC, Soto C (2015) Type 2 Diabetes as a protein misfolding Disease. Trends Mol Med 21:439–449. https://doi.org/10.1016/j.molmed.2015.04.005

Article  CAS  PubMed  PubMed Central  Google Scholar 

Nadkarni AK (1978) Indian material medica. Popular Prakashan Pvt Ltd. Mumbai

Narayanan M, Gopi A, Natarajan D, Kandasamy S, Saravanan M, El Askary A, Elfasakhany A, Pugazhendhi A (2021) Hepato and nephroprotective activity of methanol extract of Hygrophila Spinosa and its antibacterial potential against multidrug resistant Pandoraea sputorum. Environ Res 201:111594. https://doi.org/10.1016/j.envres.2021.111594

Article  CAS  PubMed  Google Scholar 

Ohkawa H, Ohishi N, Yagi K (1979) Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 95:351–358. https://doi.org/10.1016/0003-2697(79)90738-3

Article  CAS  PubMed  Google Scholar 

Paoletti F, Aldinucci D, Mocali A, Caparrini A (1986) A sensitive spectrophotometric method for the determination of superoxide dismutase activity in tissue extracts. Anal Biochem 154:536–541. https://doi.org/10.1016/0003-2697(86)90026-6

Article  CAS  PubMed  Google Scholar 

Patra A, Jha S, Murthy PN, Aher VD, Chattopadhyay P, Panigrahi G, Roy D (2009) Antiinflammatory and antipyretic activities of Hygrophila Spinosa T. Anders leaves (Acanthaceae). Trop J Pharm Res 8:133–137. https://doi.org/10.4314/tjpr.v8i2.44521

Article  Google Scholar 

Pawar RS, Jain AP, Kashaw S, Singhai A (2006) Effect of Asteracantha longifolia on haematological parameters in rats. Indian J Pharmacol 38:285–286. https://doi.org/10.4103/0253-7613.27028

Article  Google Scholar 

Peto Á, Kósa D, Fehér P, Ujhelyi Z, Sinka D, Vecsernyés M, Szilvássy Z, Juhász B, Csanádi Z, Vígh L, Bácskay I (2020) Pharmacological overview of the BGP-15 chemical agent as a new drug candidate for the treatment of symptoms of metabolic syndrome. Molecules 25:429. https://doi.org/10.3390/molecules25020429

Article  CAS  PubMed  PubMed Central