de Visser KE, Joyce JA. The evolving Tumor microenvironment: from cancer initiation to metastatic outgrowth. Cancer Cell. 2023;41:374–403.
Eelen G, Treps L, Li X, Carmeliet P. Basic and Therapeutic aspects of Angiogenesis updated. Circ Res. 2020;127:310–29.
Article CAS PubMed Google Scholar
Rizov M, Andreeva P, Dimova I. Molecular regulation and role of angiogenesis in reproduction. Taiwan J Obstet Gynecol. 2017;56:127–32.
Augustine R, Prasad P, Khalaf IMN. Therapeutic angiogenesis: from conventional approaches to recent nanotechnology-based interventions. Mater Sci Eng C Mater Biol Appl. 2019;97:994–1008.
Article CAS PubMed Google Scholar
Guerra A, Belinha J, Jorge RN. Modelling skin wound healing angiogenesis: a review. J Theor Biol. 2018;459:1–17.
Article CAS PubMed Google Scholar
Weidner N, Semple JP, Welch WR, Folkman J. Tumor angiogenesis and Metastasis–correlation in invasive breast carcinoma. N Engl J Med. 1991;324:1–8.
Article CAS PubMed Google Scholar
Cao Y. Tumor angiogenesis and molecular targets for therapy. Front Biosci (Landmark Ed). 2009;14:3962–73.
Article CAS PubMed Google Scholar
Sluimer JC, Daemen MJ. Novel concepts in atherogenesis: angiogenesis and hypoxia in Atherosclerosis. J Pathol. 2009;218:7–29.
Lee HJ, Hong YJ, Kim M. Angiogenesis in chronic inflammatory skin disorders. Int J Mol Sci 2021, 22.
Lawler J. Counter regulation of Tumor angiogenesis by vascular endothelial growth factor and thrombospondin-1. Semin Cancer Biol. 2022;86:126–35.
Article CAS PubMed Google Scholar
Jia G, Fu Y, Zhao X, Dai Q, Zheng G, Yang Y, Yi C, Lindahl T, Pan T, Yang YG, He C. N6-methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO. Nat Chem Biol. 2011;7:885–7.
Article CAS PubMed PubMed Central Google Scholar
Han Z, Niu T, Chang J, Lei X, Zhao M, Wang Q, Cheng W, Wang J, Feng Y, Chai J. Crystal structure of the FTO protein reveals basis for its substrate specificity. Nature. 2010;464:1205–9.
Article CAS PubMed Google Scholar
Meyer KD, Saletore Y, Zumbo P, Elemento O, Mason CE, Jaffrey SR. Comprehensive analysis of mRNA methylation reveals enrichment in 3’ UTRs and near stop codons. Cell. 2012;149:1635–46.
Article CAS PubMed PubMed Central Google Scholar
Dominissini D, Moshitch-Moshkovitz S, Schwartz S, Salmon-Divon M, Ungar L, Osenberg S, Cesarkas K, Jacob-Hirsch J, Amariglio N, Kupiec M, et al. Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq. Nature. 2012;485:201–6.
Article CAS PubMed Google Scholar
Mendel M, Delaney K, Pandey RR, Chen KM, Wenda JM, Vågbø CB, Steiner FA, Homolka D, Pillai RS. Splice site m(6)a methylation prevents binding of U2AF35 to inhibit RNA splicing. Cell. 2021;184:3125–3142e3125.
Article CAS PubMed PubMed Central Google Scholar
Xiao W, Adhikari S, Dahal U, Chen YS, Hao YJ, Sun BF, Sun HY, Li A, Ping XL, Lai WY, et al. Nuclear m(6)a reader YTHDC1 regulates mRNA splicing. Mol Cell. 2016;61:507–19.
Article CAS PubMed Google Scholar
Achour C, Bhattarai DP, Groza P, Román ÁC, Aguilo F. METTL3 regulates breast cancer-associated alternative splicing switches. Oncogene. 2023;42:911–25.
Article CAS PubMed PubMed Central Google Scholar
Berulava T, Buchholz E, Elerdashvili V, Pena T, Islam MR, Lbik D, Mohamed BA, Renner A, von Lewinski D, Sacherer M, et al. Changes in m6A RNA methylation contribute to Heart Failure progression by modulating translation. Eur J Heart Fail. 2020;22:54–66.
Article CAS PubMed Google Scholar
Sendinc E, Valle-Garcia D, Dhall A, Chen H, Henriques T, Navarrete-Perea J, Sheng W, Gygi SP, Adelman K, Shi Y. PCIF1 catalyzes m6Am mRNA methylation to regulate Gene expression. Mol Cell. 2019;75:620–630e629.
Article CAS PubMed PubMed Central Google Scholar
Yang B, Wang JQ, Tan Y, Yuan R, Chen ZS, Zou C. RNA methylation and cancer treatment. Pharmacol Res. 2021;174:105937.
Article CAS PubMed Google Scholar
Ma S, Chen C, Ji X, Liu J, Zhou Q, Wang G, Yuan W, Kan Q, Sun Z. The interplay between m6A RNA methylation and noncoding RNA in cancer. J Hematol Oncol. 2019;12:121.
Article PubMed PubMed Central Google Scholar
Shen W, Pu J, Zuo Z, Gu S, Sun J, Tan B, Wang L, Cheng J, Zuo Y. The RNA demethylase ALKBH5 promotes the progression and angiogenesis of Lung cancer by regulating the stability of the LncRNA PVT1. Cancer Cell Int. 2022;22:353.
Article CAS PubMed PubMed Central Google Scholar
Fang H, Sun Q, Zhou J, Zhang H, Song Q, Zhang H, Yu G, Guo Y, Huang C, Mou Y, et al. M(6)a methylation reader IGF2BP2 activates endothelial cells to promote angiogenesis and Metastasis of lung adenocarcinoma. Mol Cancer. 2023;22:99.
Article CAS PubMed PubMed Central Google Scholar
Zhang H, Zhou J, Li J, Wang Z, Chen Z, Lv Z, Ge L, Xie G, Deng G, Rui Y, et al. N6-Methyladenosine promotes translation of VEGFA to accelerate angiogenesis in Lung Cancer. Cancer Res. 2023;83:2208–25.
Article CAS PubMed Google Scholar
Folkman J. Tumor angiogenesis: therapeutic implications. N Engl J Med. 1971;285:1182–6.
Article CAS PubMed Google Scholar
Edlund S, Landström M, Heldin CH, Aspenström P. Transforming growth factor-beta-induced mobilization of actin cytoskeleton requires signaling by small GTPases Cdc42 and RhoA. Mol Biol Cell. 2002;13:902–14.
Article CAS PubMed PubMed Central Google Scholar
Panneerdoss S, Eedunuri VK, Yadav P, Timilsina S, Rajamanickam S, Viswanadhapalli S, Abdelfattah N, Onyeagucha BC, Cui X, Lai Z, et al. Cross-talk among writers, readers, and erasers of m(6)a regulates cancer growth and progression. Sci Adv. 2018;4:eaar8263.
Article CAS PubMed PubMed Central Google Scholar
Kumar A, Cherukumilli M, Mahmoudpour SH, Brand K, Bandapalli OR. ShRNA-mediated knock-down of CXCL8 inhibits Tumor growth in colorectal liver Metastasis. Biochem Biophys Res Commun. 2018;500:731–7.
Article CAS PubMed Google Scholar
Kumaradevan S, Lee SY, Richards S, Lyle C, Zhao Q, Tapan U, Jiangliu Y, Ghumman S, Walker J, Belghasem M, et al. c-Cbl expression correlates with human Colorectal Cancer survival and its Wnt/β-Catenin suppressor function is regulated by Tyr371 phosphorylation. Am J Pathol. 2018;188:1921–33.
Article CAS PubMed PubMed Central Google Scholar
Yang P, Yu D, Zhou J, Zhuang S, Jiang T. TGM2 interference regulates the angiogenesis and apoptosis of Colorectal cancer via Wnt/β-catenin pathway. Cell Cycle. 2019;18:1122–34.
Article CAS PubMed PubMed Central Google Scholar
Mosimann C, Hausmann G, Basler K. Beta-catenin hits chromatin: regulation of wnt target gene activation. Nat Rev Mol Cell Biol. 2009;10:276–86.
Article CAS PubMed Google Scholar
Pi J, Wang W, Ji M, Wang X, Wei X, Jin J, Liu T, Qiang J, Qi Z, Li F, et al. YTHDF1 promotes gastric carcinogenesis by Controlling translation of FZD7. Cancer Res. 2021;81:2651–65.
Article CAS PubMed Google Scholar
Zhang PC, Liu X, Li MM, Ma YY, Sun HT, Tian XY, Wang Y, Liu M, Fu LS, Wang YF, et al. AT-533, a novel Hsp90 inhibitor, inhibits Breast cancer growth and HIF-1α/VEGF/VEGFR-2-mediated angiogenesis in vitro and in vivo. Biochem Pharmacol. 2020;172:113771.
Article CAS PubMed Google Scholar
Dewangan J, Srivastava S, Mishra S, Divakar A, Kumar S, Rath SK. Salinomycin inhibits Breast cancer progression via targeting HIF-1α/VEGF mediated Tumor angiogenesis in vitro and in vivo. Biochem Pharmacol. 2019;164:326–35.
Article CAS PubMed Google Scholar
Jiang S, Gao Y, Yu QH, Li M, Cheng X, Hu SB, Song ZF, Zheng QC. P-21-activated kinase 1 contributes to Tumor angiogenesis upon photodynamic therapy via the HIF-1α/VEGF pathway. Biochem Biophys Res Commun. 2020;526:98–104.
Comments (0)