Effects of Endoscopic Sinus Surgery on Olfactory Function

Croy I, Nordin S, Hummel T. Olfactory disorders and quality of life–an updated review. Chem Senses. 2014;39:185–94.

Article  PubMed  Google Scholar 

Youssef AS, Sampath R, Freeman JL, Mattingly JK, Ramakrishnan VR. Unilateral endonasal transcribriform approach with septal transposition for olfactory groove meningioma: can olfaction be preserved? Acta Neurochir (Wien). 2016;158:1965–72.

Article  PubMed  Google Scholar 

Siegel JK, Kung SY, Wroblewski KE, Kern DW, McClintock MK, Pinto JM. Olfaction is associated with sexual motivation and satisfaction in older men and women. J Sex Med. 2021;18:295–302.

Article  PubMed  PubMed Central  Google Scholar 

Boesveldt S, Parma V. The importance of the olfactory system in human well-being, through nutrition and social behavior. Cell Tissue Res. 2021;383:559–67.

Article  PubMed  PubMed Central  Google Scholar 

Miwa T, Furukawa M, Tsukatani T, Costanzo RM, DiNardo LJ, Reiter ER. Impact of olfactory impairment on quality of life and disability. Arch Otolaryngol Neck Surg. 2001;127:497–503.

Article  CAS  Google Scholar 

AlRasheed MM, Al-Aqeel S, Aboheimed GI, AlRasheed NM, Abanmy NO, Alhamid GA, et al. Quality of life, fatigue, and physical symptoms post-COVID-19 condition: a cross-sectional comparative study. Healthcare. 2023;11:1660.

Article  PubMed  PubMed Central  Google Scholar 

Burges Watson DL, Campbell M, Hopkins C, Smith B, Kelly C, Deary V. Altered smell and taste: anosmia, parosmia and the impact of long Covid-19. PLoS ONE. 2021;16:e0256998.

Article  CAS  PubMed  PubMed Central  Google Scholar 

•• Fokkens WJ, Lund VJ, Hopkins C, Hellings PW, Kern R, Reitsma S, et al. European Position Paper on Rhinosinusitis and Nasal Polyps 2020. Rhinology. 2020;58:1–464. European guideline on rhinosinusitis and nasal polyps.

Article  PubMed  Google Scholar 

•• Orlandi RR, Kingdom TT, Smith TL, Bleier B, DeConde A, Luong AU, et al. International consensus statement on allergy and rhinology: rhinosinusitis 2021. Int Forum Allergy Rhinol. 2021;11:213–739. Current American guidelines on the CRS management.

Article  PubMed  Google Scholar 

Wang W, Shokri T, Manolidis S, Ducic Y. Complications in skull base surgery and subsequent repair. Semin Plast Surg. 2020;34:286–92.

Article  PubMed  PubMed Central  Google Scholar 

Puccinelli CL, Yin LX, O’Brien EK, Gompel JJ, Choby GW, Abel KM, et al. Long-term olfaction outcomes in transnasal endoscopic skull-base surgery: a prospective cohort study comparing electrocautery and cold knife upper septal limb incision techniques. Int Forum Allergy Rhinol. 2019;9:493–500.

Article  PubMed  Google Scholar 

Upadhyay S, Buohliqah L, Dolci RLL, Otto BA, Prevedello DM, Carrau RL. Periodic olfactory assessment in patients undergoing skull base surgery with preservation of the olfactory strip. Laryngoscope. 2017;127:1970–5.

Article  PubMed  Google Scholar 

Choi R, Goldstein BJ. Olfactory epithelium: cells, clinical disorders, and insights from an adult stem cell niche. Laryngoscope Investig Otolaryngol. 2018;3:35–42.

Article  PubMed  PubMed Central  Google Scholar 

Pinto JM. Olfaction. Proc Am Thorac Soc. 2011;8:46–52.

Article  PubMed  Google Scholar 

Branigan B, Tadi P. Physiology, olfactory. StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 [cited 2023 Jul 10]. Available from: http://www.ncbi.nlm.nih.gov/books/NBK542239/.

Kern RC. Chronic sinusitis and anosmia: pathologic changes in the olfactory mucosa. Laryngoscope. 2000;110:1071–7.

Article  CAS  PubMed  Google Scholar 

Yee KK, Pribitkin EA, Cowart BJ, Vainius AA, Klock CT, Rosen D, et al. Neuropathology of the olfactory mucosa in chronic rhinosinusitis. Am J Rhinol Allergy. 2010;24:110–20.

Article  PubMed  Google Scholar 

Sultan B, May LA, Lane AP. The role of TNF-α in inflammatory olfactory loss. Laryngoscope. 2011;121:2481–6.

Article  CAS  PubMed  PubMed Central  Google Scholar 

• Zhao R, Chen K, Tang Y. Olfactory changes after endoscopic sinus surgery for chronic rhinosinusitis: a meta-analysis. Clin Otolaryngol. 2021;46:41–51. Only meta-analysis about olfaction in CRSwNP and CRsNP after ESS.

Article  PubMed  Google Scholar 

Hintschich CA, Pade J, Petridis P, Hummel T. Presurgical olfactory function as an indicator of the outcome of functional endoscopic sinus surgery in chronic rhinosinusitis with nasal polyps. Eur Arch Otorhinolaryngol. 2022;279:5727–33.

Article  PubMed  PubMed Central  Google Scholar 

Hernandez AK, Wendler O, Mayr S, Iro H, Hummel T, Mueller SK. Predictors of olfactory improvement after endoscopic sinus surgery in chronic rhinosinusitis with nasal polyps. J Laryngol Otol. 2023;137:524–31.

Article  CAS  PubMed  Google Scholar 

Ye P, He S, Tang S, Xie X, Duan C, Zhang L, et al. Improvement of subjective olfactory dysfunction in chronic rhinosinusitis with nasal polyps after endoscopic sinus surgery. Front Surg. 2022;9:870682.

Article  PubMed  PubMed Central  Google Scholar 

Dadgarnia M, Rahmani A, Baradaranfar M, Atighechi S, Zand V, Meybodian M, et al. The relationship between endoscopic and radiologic findings and olfactory status of patients with chronic rhinosinusitis with nasal polyps before and after the endoscopic sinus surgery. Eur Arch Otorhinolaryngol. 2019;276:397–400.

Article  PubMed  Google Scholar 

Gomes SC, Cavaliere C, Masieri S, Van Zele T, Gevaert P, Holtappels G, et al. Reboot surgery for chronic rhinosinusitis with nasal polyposis: recurrence and smell kinetics. Eur Arch Otorhinolaryngol. 2022;279:5691–9.

Article  PubMed  Google Scholar 

Kashiwagi T, Tsunemi Y, Akutsu M, Nakajima I, Haruna S. Postoperative evaluation of olfactory dysfunction in eosinophilic chronic rhinosinusitis - comparison of histopathological and clinical findings. Acta Otolaryngol (Stockh). 2019;139:881–9.

Article  PubMed  Google Scholar 

Smith TL, Schlosser RJ, Mace JC, Alt JA, Beswick DM, DeConde AS, et al. Long-term outcomes of endoscopic sinus surgery in the management of adult chronic rhinosinusitis. Int Forum Allergy Rhinol. 2019;9:831–41.

Article  PubMed  PubMed Central  Google Scholar 

• Wu D, Li Y, Bleier BS, Wei Y. Superior turbinate eosinophilia predicts olfactory decline in patients with chronic rhinosinusitis. Ann Allergy Asthma Immunol. 2020;125:304-310.e1. Prospective study that showed how the percentage of eosinophils relates to the recurrence of a decline in olfaction after ESS in CRS.

Article  PubMed  Google Scholar 

Han JK, Bachert C, Fokkens W, Desrosiers M, Wagenmann M, Lee SE, et al. Mepolizumab for chronic rhinosinusitis with nasal polyps (SYNAPSE): a randomised, double-blind, placebo-controlled, phase 3 trial. Lancet Respir Med. 2021;9:1141–53.

Article  CAS  PubMed  Google Scholar 

Seys SF, De Bont S, Fokkens WJ, Bachert C, Alobid I, Bernal-Sprekelsen M, et al. Real-life assessment of chronic rhinosinusitis patients using mobile technology: the mySinusitisCoach project by EUFOREA. Allergy. 2020;75:2867–78.

Article  PubMed  Google Scholar 

Calus L, Van Bruaene N, Bosteels C, Dejonckheere S, Van Zele T, Holtappels G, et al. Twelve-year follow-up study after endoscopic sinus surgery in patients with chronic rhinosinusitis with nasal polyposis. Clin Transl Allergy. 2019;9:30.

Article  PubMed  PubMed Central  Google Scholar 

Jiang R-S, Shih K-H, Liang K-L. Effect of functional endoscopic sinus surgery on gustatory function in patients with chronic rhinosinusitis. Ear Nose Throat J. 2021;1455613211015754.

Akiyama K, Samukawa Y, Hoshikawa H. Short-term outcomes of olfaction in patients with eosinophilic chronic rhinosinusitis after endoscopic sinus surgery and an assessment of prognostic factors. Int Forum Allergy Rhinol. 2020;10:208–16.

Article  PubMed  Google Scholar 

Zhang L, Zhang Y, Gao Y, Wang K, Lou H, Meng Y, et al. Long-term outcomes of different endoscopic sinus surgery in recurrent chronic rhinosinusitis with nasal polyps and asthma. Rhinology. 2020;58:126–35.

CAS  PubMed  Google Scholar 

Musleh A, Al-Zomia AS, Shahrani IM, Alshehri A, Alwadie A, Alqhtani F, et al. Olfactory change pattern after endoscopic sinus surgery in chronic rhinosinusitis patients. Cureus. 2022;14:e24597.

PubMed  PubMed Central  Google Scholar 

Yousefi J, Madarshahi H, Akhavan A, Taheri A, Saeedi M, Bagherihagh A, et al. Effect of ESS on olfactory threshold of patients with CRS without nasal polyps. Int Tinnitus J. 2018;22:89–92.

Article  PubMed  Google Scholar 

Özcan C, İsmi O, Meşe F, Gürses İ, Vayisoğlu Y, Görür K. Olfactory neuroepithelium in olfactory cleft polyps: do they have any effect on olfaction results after endoscopic sinus surgery? Turk Arch Otorhinolaryngol. 2022;60:65–71.

Article  PubMed  PubMed Central  Google Scholar 

Cingi C, Bayar Muluk N, Mitsias DI, Papadopoulos NG, Klimek L, Laulajainen-Hongisto A, et al. The nose as a route for therapy: part 1. Pharmacotherapy Front Allergy. 2021;22(2):638136.

Article  Google Scholar 

Jafari A, Holbrook EH. Therapies for olfactory dysfunction — an update. Curr Allergy Asthma Rep. 2022;22:21–8.

Article  CAS  PubMed  PubMed Central  Google Scholar 

• Dharmarajan H, Falade O, Lee SE, Wang EW. Outcomes of dupilumab treatment versus endoscopic sinus surgery for chronic rhinosinusitis with nasal polyps. Int Forum Allergy Rhinol. 2022;12:986–95. Recent study that showed Dupilumab superiority in olfaction and symptoms improvement in comparison to ESS.

Article  PubMed  Google Scholar 

Desrosiers M, Mannent LP, Amin N, Canonica GW, Hellings PW, Gevaert P, et al. Dupilumab reduces systemic corticosteroid use and sinonasal surgery rate in CRSwNP. Rhinology. 2021;59:301–11.

Comments (0)

No login
gif