Rowe RG, Daley GQ. Induced pluripotent stem cells in disease modelling and drug discovery. Nat Rev Genet. 2019;20:377–88.
Article CAS PubMed PubMed Central Google Scholar
Li L, Papadopoulos V. Advances in stem cell research for the treatment of primary hypogonadism. Nat Rev Urol. 2021;18:487–507.
Article CAS PubMed Google Scholar
Lawrence M, Evans A, Moreau T, Bagnati M, Smart M, Hassan E, et al. Process analysis of pluripotent stem cell differentiation to megakaryocytes to make platelets applying European GMP. NPJ Regen Med. 2021;6:27.
Article PubMed PubMed Central Google Scholar
Chandrasekaran V, Carta G, da Costa PD, Gupta R, Murphy C, Feifel E, et al. Generation and characterization of iPSC-derived renal proximal tubule-like cells with extended stability. Sci Rep. 2021;11:11575.
Article CAS PubMed PubMed Central Google Scholar
Shi Y, Inoue H, Wu JC, Yamanaka S. Induced pluripotent stem cell technology: a decade of progress. Nat Rev Drug Discov. 2017;16:115–30.
Article CAS PubMed Google Scholar
Duff C, Baruteau J. Modelling urea cycle disorders using iPSCs. NPJ Regen Med. 2022;7:56.
Article CAS PubMed PubMed Central Google Scholar
de Rus JA, Denis HL, Cicchetti F, Alpaugh M. Current and future applications of induced pluripotent stem cell-based models to study pathological proteins in neurodegenerative disorders. Mol Psychiatry. 2021;26:2685–706.
Hiratsuka K, Monkawa T, Akiyama T, Nakatake Y, Oda M, Goparaju SK, et al. Induction of human pluripotent stem cells into kidney tissues by synthetic mRNAs encoding transcription factors. Sci Rep. 2019;9:913.
Article PubMed PubMed Central Google Scholar
Zhang W, Ross PJ, Ellis J, Salter MW. Targeting NMDA receptors in neuropsychiatric disorders by drug screening on human neurons derived from pluripotent stem cells. Transl Psychiatry. 2022;12:243.
Article CAS PubMed PubMed Central Google Scholar
Ji S, Xiong M, Chen H, Liu Y, Zhou L, Hong Y, et al. Cellular rejuvenation: molecular mechanisms and potential therapeutic interventions for diseases. Signal Transduct Target Ther. 2023;8:116.
Article PubMed PubMed Central Google Scholar
Araki R, Hoki Y, Suga T, Obara C, Sunayama M, Imadome K, et al. Genetic aberrations in iPSCs are introduced by a transient G1/S cell cycle checkpoint deficiency. Nat Commun. 2020;11:197.
Article CAS PubMed PubMed Central Google Scholar
Taguchi J, Shibata H, Kabata M, Kato M, Fukuda K, Tanaka A, et al. DMRT1-mediated reprogramming drives development of cancer resembling human germ cell tumors with features of totipotency. Nat Commun. 2021;12:5041.
Article CAS PubMed PubMed Central Google Scholar
Supharattanasitthi W, Carlsson E, Sharif U, Paraoan L. CRISPR/Cas9-mediated one step bi-allelic change of genomic DNA in iPSCs and human RPE cells in vitro with dual antibiotic selection. Sci Rep. 2019;9:174.
Article PubMed PubMed Central Google Scholar
Maruoka S, Ojima T, Iwamoto H, Kitadani J, Tabata H, Tominaga S, et al. Tumor RNA transfected DCs derived from iPS cells elicit cytotoxicity against cancer cells induced from colorectal cancer patients in vitro. Sci Rep. 2022;12:3295.
Article CAS PubMed PubMed Central Google Scholar
Marin Navarro A, Susanto E, Falk A, Wilhelm M. Modeling cancer using patient-derived induced pluripotent stem cells to understand development of childhood malignancies. Cell death Discov. 2018;4:7.
Article PubMed PubMed Central Google Scholar
Ueda T, Shiina S, Iriguchi S, Terakura S, Kawai Y, Kabai R, et al. Optimization of the proliferation and persistency of CAR T cells derived from human induced pluripotent stem cells. Nat Biomed Eng. 2023;7:24–37.
Article CAS PubMed Google Scholar
Ghosh S, Nehme R, Barrett LE. Greater genetic diversity is needed in human pluripotent stem cell models. Nat Commun. 2022;13(1):7301.
Article CAS PubMed PubMed Central Google Scholar
Wiegand C, Banerjee I. Recent advances in the applications of iPSC technology. Curr Opin Biotechnol. 2019;60:250–8.
Article CAS PubMed Google Scholar
Aboul-Soud MAM, Alzahrani AJ, Mahmoud A. Induced pluripotent stem cells (iPSCs)—roles in regenerative therapies, disease modelling and drug screening. Cells. 2021;10(9):2319.
Article CAS PubMed PubMed Central Google Scholar
Peñalosa-Ruiz G, Bright AR, Mulder KW, Veenstra GJC. The interplay of chromatin and transcription factors during cell fate transitions in development and reprogramming. Biochim Biophys Acta - Gene Regul Mech. 2019;1862: 194407.
Lange L, Esteban MA, Schambach A. Back to pluripotency: fully chemically induced reboot of human somatic cells. Signal Transduct Target Ther. 2022;7:244.
Article PubMed PubMed Central Google Scholar
Fathi M, Riazi SS, Pourdamghan N. Triple-negative Breast Cancer Therapy Using RNA Nanoparticles Targeting Stem Cell Markers with Anti-miRNA: A Systematic Review and Meta-Analysis. Int J Sci Res Dent Med Sci. 2023;5(2):96–101.
Chakrabarty K, Shetty R, Argulwar S, Das D, Ghosh A. Induced pluripotent stem cell-based disease modeling and prospective immune therapy for coronavirus disease 2019. Cytotherapy. 2022;24:235–48.
Article CAS PubMed Google Scholar
Papapetrou EP. Patient-derived induced pluripotent stem cells in cancer research and precision oncology. Nat Med. 2016;22:1392–401.
Article CAS PubMed PubMed Central Google Scholar
Zhou Y, Li M, Zhou K, Brown J, Tsao T, Cen X, et al. Engineering induced pluripotent stem cells for cancer immunotherapy. Cancers (Basel). 2022;14(9):2266.
Article CAS PubMed Google Scholar
Sayed N, Liu C, Wu JC. Translation of Human-Induced Pluripotent Stem Cells: From Clinical Trial in a Dish to Precision Medicine. J Am Coll Cardiol. 2016;67:2161–76.
Article PubMed PubMed Central Google Scholar
Sharkis SJ, Jones RJ, Civin C, Jang Y-Y. Pluripotent stem cell-based cancer therapy: promise and challenges. Sci Transl Med. 2012;4:127ps9.
Article PubMed PubMed Central Google Scholar
Griscelli F, Féraud O, Oudrhiri N, Gobbo E, Casal I, Chomel J-C, et al. Malignant germ cell-like tumors, expressing Ki-1 antigen (CD30), are revealed during in vivo differentiation of partially reprogrammed human-induced pluripotent stem cells. Am J Pathol. 2012;180:2084–96.
Article CAS PubMed Google Scholar
Câmara DAD, Mambelli LI, Porcacchia AS, Kerkis I. Advances and challenges on cancer cells reprogramming using induced pluripotent stem cells technologies. J Cancer. 2016;7:2296–303.
Article PubMed PubMed Central Google Scholar
Moquin-Beaudry G, Benabdallah B, Maggiorani D, Le O, Li Y, Colas C, et al. Autologous humanized mouse models of iPSC-derived tumors enable characterization and modulation of cancer-immune cell interactions. Cell Rep Methods. 2022;2: 100153.
Article CAS PubMed PubMed Central Google Scholar
Steeg R, Mueller SC, Mah N, Holst B, Cabrera-Socorro A, Stacey GN, et al. EBiSC best practice: How to ensure optimal generation, qualification, and distribution of iPSC lines. Stem Cell Rep. 2021;16:1853–67.
Daley GQ, Hyun I, Apperley JF, Barker RA, Benvenisty N, Bredenoord AL, et al. Setting global standards for stem cell research and clinical translation: the 2016 ISSCR guidelines. Stem Cell Rep. 2016;6:787–97.
Watanabe N, Santostefano KE, Yachnis AT, Terada N. A pathologist’s perspective on induced pluripotent stem cells. Lab Investig. 2017;97:1126–32.
Biglari N, Mehdizadeh A, Mastanabad MV, Gharaeikhezri MH, Afrakoti LG, Pourbala H, et al. Application of mesenchymal stem cells (MSCs) in neurodegenerative disorders: history, findings, and prospective challenges. Pathol Res Pract. 2023:154541.
Wuputra K, Ku C-C, Wu D-C, Lin Y-C, Saito S, Yokoyama KK. Prevention of tumor risk associated with the reprogramming of human pluripotent stem cells. J Exp Clin Cancer Res. 2020;39:1–24.
Krog RT, de Miranda NFCC, Vahrmeijer AL, Kooreman NG. The potential of induced pluripotent stem cells to advance the treatment of pancreatic ductal adenocarcinoma. Cancers (Basel). 2021;13(22):5789.
Article CAS PubMed Google Scholar
Shamsian A, Sahebnasagh R, Norouzy A, Hussein SH, Ghahremani MH, Azizi Z. Cancer cells as a new source of induced pluripotent stem cells. Stem Cell Res Ther. 2022;13:459.
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