Zhu N, Zhang D, Wang W, Li X, Yang B, Song J, et al. China novel coronavirus investigating and research team, a novel coronavirus from patients with pneumonia in China, 2019. N Engl J Med. 2020;382:727–33.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lu R, Zhao X, Li J, Niu P, Yang B, Wu H, et al. Genomic characterization and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding. Lancet. 2020;395:565–74.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Abobaker A, Raba A, Alzwi A. Extrapulmonary and atypical clinical presentations of COVID-19. J Med Virol. 2020;92:2458–64.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Xia J, Tong J, Liu M, Shen Y, Guo D. Evaluation of coronavirus in tears and conjunctival secretions of patients with SARS-CoV-2 infection. J Med Virol. 2020;92:589–94.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Güemes N, Burgos B, García J, Saenz F, Arriola P, Martinez M, et al. Conjunctivitis in COVID-19 patients: frequency and clinical presentation. Graefes Arch Clin Exp Ophthalmol. 2020;11:2501–7.

Article  Google Scholar 

Aggarwal K, Agarwal A, Jaiswal N, Dahiya N, Ahuja A, Mahajan S, et al. Ocular surface manifestations of coronavirus disease 2019 (COVID-19): a systematic review and meta-analysis. Graefes Arch Clin Exo Ophthalmol. 2020;258:2501–7.

Google Scholar 

Nasiri N, Sharifi H, Bazrafshan A, Noori A, Karamouzian M, Sharifi A. Ocular manifestations of COVID-19: a systematic review and meta-analysis. J Ophthalmic Vis Res. 2021;16:103–12.

PubMed  PubMed Central  Google Scholar 

Loffredo L, Pacella F, Pacella E, Tiscione G, Oliva A, Violi F. Conjunctivitis and COVID-19: a meta-analysis. L Med Virol. 2020;92:1413–4.

Article  CAS  Google Scholar 

Sen M, Honavar SG, Sharma N, Sachdev M. COVID-19 and eye: a review of ophthalmic manifestations of COVID-19. Indian J Ophthalmol. 2021;69:488–509.

Article  PubMed  PubMed Central  Google Scholar 

National Institute of Infectious Diseases. Annual report of the sentinel surveillance from the National Epidemiological Surveillance of Infectious Diseases in Japan. 2019. https://www.niid.go.jp/niid/ja/annual-r1.html (in Japanese)

Cheema M, Aghazadeh H, Nazarali S, Ting A, Hodges J, McFarlane A, et al. Keratoconjunctivitis as the initial medical presentation of the novel coronavirus disease 2019 (COVID-19). Can J Ophthalmol. 2020;55:e125–9.

Article  PubMed  PubMed Central  Google Scholar 

Wu P, Duan F, Luo C, Liu Q, Qu X, Liang L, et al. Characteristics of ocular findings of patients with coronavirus disease 2019 (COVID-19) in Hubei province China. JAMA Ophthalmol. 2020;138:575–8.

Article  PubMed  PubMed Central  Google Scholar 

Patel S, Tohme N, Gorrin E, Kumar N, Goldhagen B, Galor A. Prevalence and risk factors for chalazion in an older veteran population. Br J Ophthalmol. 2022;106:1200–5.

Article  PubMed  Google Scholar 

Hoffmann M, Kleine-Weber H, Schroeder S, Kruger N, Herrler T, Erichsen S, et al. SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2 and is blocked by a clinically proven protease inhibitor. Cell. 2020;181:271–80.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Leung J, Yang C, Tam A, Shaipanich T, Hackett T, Singhera G, et al. ACE-2 expression in the small airway epithelia of smokers and COPD patients: implications for COVID-19. Eur Resp J. 2020;55:2000688.

Article  CAS  Google Scholar 

Singh S, Garcia G Jr, Shah R, Kramerov AA, Wright RE, Spektor TM, et al. SARS-CoV-2 and its beta variant of concern infect human conjunctival epithelial cells and induce differential antiviral innate immune response. Ocul Surf. 2022;23:184–94.

Article  PubMed  Google Scholar 

Guan WJ, Ni ZY, Hu Y, Ou CQ, He JX, Liu L, et al. Clinical characteristics of coronavirus disease 2019 in China. N Engl J Med. 2020;382:1708–20.

Article  CAS  PubMed  Google Scholar 

Guan WJ, Liang WH, Zhao Y, Liang HR, Chen ZS, Li YM, et al. Comorbidity and its impact on 1590 patients with COVID-19 in China: a nationwide analysis. Eur Respir J. 2020;14(55):2000547.

Article  Google Scholar 

Emami A, Javanmardi F, Pirbonyeh N, Akbari A. Prevalence of underlying diseases in hospitalized patients with COVID-19: a systematic review and meta-analysis. Arch Acad Emerg Med. 2020;24(8):e35.

Google Scholar 

Lippi G, Henry BM. Active smoking is not associated with severity of coronavirus disease 2019 (COVID-19). Eur J Intern Med. 2020;75:107–8.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhou Y, Duan C, Zeng Y, Tong Y, Nie Y, Yang Y, et al. Ocular findings and proportion with conjunctival SARS-COV-2 in COVID-19 patients. Ophthalmology. 2020;127:982–3.

Article  PubMed  Google Scholar