Yin Y, Liu K, Li G. Protective effect of prim-O-Glucosylcimifugin on ulcerative colitis and its mechanism. Front Pharmacol. 2022;18(13):882924. https://doi.org/10.3389/fphar.2022.882924.PMID:35662727;PMCID:PMC9158503.
Yang J, Miao L, Xue Y, Wang X. Yiyi Fuzi Baijiang powder alleviates dextran sulfate sodium-induced ulcerative colitis in rats via inhibiting the TLR4/NF-κB/NLRP3 inflammasome signaling pathway to repair the intestinal epithelial barrier, and modulating intestinal microbiota. Oxid Med Cell Longev. 2023;14(2023):3071610. https://doi.org/10.1155/2023/3071610.PMID:36691639;PMCID:PMC9867587.
Chen S, Liu H, Li Z, Tang J, Huang B, Zhi F, Zhao X. Epithelial PBLD attenuates intestinal inflammatory response and improves intestinal barrier function by inhibiting NF-κB signaling. Cell Death Dis. 2021;12(6):563. https://doi.org/10.1038/s41419-021-03843-0.PMID:34059646;PMCID:PMC8166876.
Article CAS PubMed PubMed Central Google Scholar
Peng S, Shen L, Tian MX, Li HM, Wang SS. Poly(ADP-ribose) polymerase-1 inhibitor ameliorates dextran sulfate sodium-induced colitis in mice by regulating the balance of Th17/Treg cells and inhibiting the NF-κB signaling pathway. Exp Ther Med. 2021;21(2):134. https://doi.org/10.3892/etm.2020.9566. Epub 2020 Dec 10. PMID: 33376516; PMCID: PMC7751469.
Article CAS PubMed Google Scholar
Yamamoto Y, Masuda G, Kushiyama S, Maruo K, Tsujio G, Sera T, Sugimoto A, Nishimura S, Kuroda K, Togano S, Okuno T, Ohira M, Yashiro M. Establishment of a gastric cancer cell line with high microsatellite instability, OCUM-13, derived from Borrmann type-2 primary tumor. Cancer Med. 2022;12:6016. https://doi.org/10.1002/cam4.5403. PubMed PMID: 36324252.
Article CAS PubMed PubMed Central Google Scholar
Li X, Sun L, Chen L, Xu Y, Kong X. Upregulation of microRNA-219–5p relieves ulcerative colitis through balancing the differentiation of Treg/Th17 cells. Eur J Gastroenterol Hepatol. 2020;32(7):813–20. https://doi.org/10.1097/MEG.0000000000001712. pii: 00042737-202007000-00006 PubMed PMID: 32175983.
Article CAS PubMed PubMed Central Google Scholar
Stevanin M, Busso N, Chobaz V, Pigni M, Ghassem-Zadeh S, Zhang L, et al. CD11b Regulates the Treg/Th17 balance in murine arthritis via IL-6. Eur J Immunol. 2017;47(4):637–45. https://doi.org/10.1002/eji.201646565.
Article CAS PubMed Google Scholar
Wei C, Wang JY, Xiong F, Wu BH, Luo MH, Yu ZC, Liu TT, Li DF, Tang Q, Li YX, Zhang DG, Xu ZL, Jin HT, Wang LS, Yao J. Curcumin ameliorates DSS-induced colitis in mice by regulating the Treg/Th17 signaling pathway. Mol Med Rep. 2021;23(1):pii:34. https://doi.org/10.3892/mmr.2020.11672. PubMed PMID: 33179078.
Yan S, Wang P, Wei H, Jia R, Zhen M, Li Q, Xue C, Li J. Treatment of ulcerative colitis with Wu-Mei-Wan by inhibiting intestinal inflammatory response and repairing damaged intestinal mucosa. Phytomedicine. 2022;105:154362. https://doi.org/10.1016/j.phymed.2022.154362. pii: S0944-7113(22)00441-X PubMed PMID: 35947900.
Article CAS PubMed Google Scholar
Gupta M, Mishra V, Gulati M, Kapoor B, Kaur A, Gupta R, Tambuwala MM. Natural compounds as safe therapeutic options for ulcerative colitis. Inflammopharmacology. 2022;30(2):397–434. https://doi.org/10.1007/s10787-022-00931-1.10.1007/s10787-022-00931-1. PubMed PMID: 35212849.
Article CAS PubMed PubMed Central Google Scholar
De Andrade SF, Da Silva LM, Golbabapour S, Harakeh S. Herbal medicines useful to treat inflammatory and ulcerative gastrointestinal disorders: preclinical and clinical studies. Evid Based Complement Alternat Med. 2018;2018:3605748. https://doi.org/10.1155/2018/3605748. PubMed PMID: 29785190.
Article PubMed PubMed Central Google Scholar
Lin Z, Wu H, Fu Y, Dai S. Application of Herbaceous medications for inflammatory bowel disease as a complementary and alternative therapy. Inflamm Bowel Dis. 2019;25(12):1886–95. https://doi.org/10.1093/ibd/izz190. pii: 5557802 PubMed PMID: 31504527.
Zhong Y, Zheng XB, Ye H, Guo M, Wu Q, Zou Y, Chi HG, Zhu YZ. Effect of Shaoyao Tang on ulcerative colitis in rats via regulation of TLR4/NF-κB signal pathway. Zhongguo Zhong Yao Za Zhi. 2019;44(7):1450–6. https://doi.org/10.19540/j.cnki.cjcmm.20181213.007. PubMed PMID: 31090304.
Wu J, Luo Y, Shen Y, Hu Y, Zhu F, Wu J, Liu Y. Integrated metabonomics and network pharmacology to reveal the action mechanism effect of Shaoyao decoction on ulcerative colitis. Drug Des Devel Ther. 2022;16:3739–76. https://doi.org/10.2147/DDDT.S375281. pii: 375281 PubMed PMID: 36324421.
Article CAS PubMed PubMed Central Google Scholar
Chi H, Wang D, Chen M, Lin J, Zhang S, Yu F, Zhou J, Zheng X, Zou Y. Shaoyao decoction inhibits inflammation and improves intestinal barrier function in mice with dextran sulfate sodium-induced colitis. Front Pharmacol. 2021;20(12):524287. https://doi.org/10.3389/fphar.2021.524287.PMID:33959000;PMCID:PMC8093868.
Szandruk-Bender M, Nowak B, Merwid-Ląd A, Kucharska AZ, Krzystek-Korpacka M, Bednarz-Misa I, Wiatrak B, Szeląg A, Piórecki N, Sozański T. Cornus mas L. Extract targets the specific molecules of the Th17/Treg developmental pathway in TNBS-induced experimental colitis in rats. Molecules. 2023;28(7):3034. https://doi.org/10.3390/molecules28073034. pii: molecules28073034 PubMed PMID: 37049797.
Article CAS PubMed PubMed Central Google Scholar
Xuan-Qing CHEN, Xiang-Yu LV, Shi-Jia LIU. Baitouweng decoction alleviates dextran sulfate sodium-induced ulcerative colitis by regulating intestinal microbiota and the IL-6/STAT3 signaling pathway. J Ethnopharmacol. 2021;265:113357. https://doi.org/10.1016/j.jep.2020.113357. pii: S0378-8741(20)33241-4 PubMed PMID: 32891820.
Article CAS PubMed Google Scholar
Wang Y, Gao J, Sun L, Li Q, Kang N, Gao C, Li T. Jia-Wei-Si-Miao-Yong-An Fang stimulates the healing of acute radiation-induced cutaneous wounds through MAPK/ERK pathway. J Ethnopharmacol. 2023;306:116180. https://doi.org/10.1016/j.jep.2023.116180. pii: S0378-8741(23)00048-X PubMed PMID: 36693549.
Article CAS PubMed Google Scholar
Zhang L, Cao N, Wang Y, Wang Y, Wu C, Cheng X, Wang C. Improvement of oxazolone-induced ulcerative colitis in rats using andrographolide. Molecules. 2019;25(1):76. https://doi.org/10.3390/molecules25010076.PMID:31878303;PMCID:PMC6982790.
Article PubMed PubMed Central Google Scholar
Jiang Y, Zhao L, Chen Q, Zhou L. Exploring the mechanism of berberine intervention in ulcerative colitis from the perspective of inflammation and immunity based on systemic pharmacology. Evid Based Complement Alternat Med. 2021;2021:9970240. https://doi.org/10.1155/2021/9970240. PubMed PMID: 34211579.
Article PubMed PubMed Central Google Scholar
Xu J, Yu P, Wu L, Liu M, Lu Y. Effect of Trichinella spiralis intervention on TNBS-induced experimental colitis in mice. Immunobiology. 2019;224(1):147–53. https://doi.org/10.1016/j.imbio.2018.09.005. Epub 2018 Oct 25 PMID: 30413272.
Article CAS PubMed Google Scholar
Shen J, Cheng J, Zhu S, Zhao J, Ye Q, Xu Y, Dong H, Zheng X. Regulating effect of baicalin on IKK/IKB/NF-kB signaling pathway and apoptosis-related proteins in rats with ulcerative colitis. Int Immunopharmacol. 2019;73:193–200. https://doi.org/10.1016/j.intimp.2019.04.052. pii: S1567-5769(18)30778-1 PubMed PMID: 31103874.
Article CAS PubMed Google Scholar
Yan JB, Luo MM, Chen ZY, He BH. The function and role of the Th17/Treg cell balance in inflammatory bowel disease. J Immunol Res. 2020;2020:8813558. https://doi.org/10.1155/2020/8813558. PubMed PMID: 33381606.
Article CAS PubMed PubMed Central Google Scholar
Fan L, Qi Y, Qu S, Chen X, Li A, Hendi M, Xu C, Wang L, Hou T, Si J, Chen SB. adolescentis ameliorates chronic colitis by regulating Treg/Th2 response and gut microbiota remodeling. Gut Microbes. 2021;13(1):1–17. https://doi.org/10.1080/19490976.2020.1826746. PubMed PMID: 33557671.
Article CAS PubMed Google Scholar
Liu YJ, Tang B, Wang FC, Tang L, Lei YY, Luo Y, Huang SJ, Yang M, Wu LY, Wang W, Liu S, Yang SM, Zhao XY. Parthenolide ameliorates colon inflammation through regulating Treg/Th17 balance in a gut microbiota-dependent manner. Theranostics. 2020;10(12):5225–41. https://doi.org/10.7150/thno.43716. pii: thnov10p5225 PubMed PMID: 32373209.
Article CAS PubMed PubMed Central Google Scholar
Khan I, Ullah N, Zha L, Bai Y, Khan A, Zhao T, Che T, Zhang C. Alteration of gut microbiota in Inflammatory Bowel Disease (IBD) cause or consequence? IBD treatment targeting the gut microbiome. Pathogens. 2019;8(3):126. https://doi.org/10.3390/pathogens8030126. pii: pathogens8030126 PubMed PMID: 31412603.
Article CAS PubMed PubMed Central Google Scholar
Ahlawat S, Kumar P, Mohan H, Goyal S, Sharma KK. Inflammatory bowel disease: tri-directional relationship between microbiota, immune system and intestinal epithelium. Crit Rev Microbiol. 2021;47(2):254–73. https://doi.org/10.1080/1040841X.2021.1876631. PubMed PMID: 33576711.
Article CAS PubMed Google Scholar
Xu H, Wu L, Nguyen HH, Mesa KR, Raghavan V, Episkopou V, Littman DR. Arkadia-SKI/SnoN signaling differentially regulates TGF-β-induced iTreg and Th17 cell differentiation. J Exp Med. 2021;218(11):e20210777. https://doi.org/10.1084/jem.20210777. pii: 212614 PubMed PMID: 34473197.
Article CAS PubMed PubMed Central Google Scholar
Rapaport AS, Ouyang W. TRIMming TGF-β signals in Th17 cells. J Exp Med. 2018;215(7):1775–6. https://doi.org/10.1084/jem.20180986. pii: jem.20180986 PubMed PMID: 29945999.
Article CAS PubMed PubMed Central Google Scholar
Bayik D, Lathia JD. Cancer stem cell-immune cell crosstalk in tumour progression. Nat Rev Cancer. 2021;21(8):526–36. https://doi.org/10.1038/s41568-021-00366-w.10.1038/s41568-021-00366-w. PubMed PMID: 34103704.
Comments (0)