Illuminating Airway Nerve Structure and Function in Chronic Cough

Kupari J, Häring M, Agirre E, Castelo-Branco G, Ernfors P (2019) An atlas of vagal sensory neurons and their molecular specialization. Cell Rep 27:2508-2523.e2504

Article  PubMed  PubMed Central  CAS  Google Scholar 

Mazzone SB, Undem BJ (2016) Vagal afferent innervation of the airways in health and disease. Physiol Rev 96:975–1024

Article  PubMed  PubMed Central  CAS  Google Scholar 

Morice AH, Millqvist E, Bieksiene K, Birring SS, Dicpinigaitis P, Domingo RC, Hilton BM, Kantar A, Lai K, McGarvey L, Rigau D, Satia I, Smith J, Song WJ, Tonia T, van den Berg JWK, van Manen MJG, Zacharasiewicz A (2020) ERS guidelines on the diagnosis and treatment of chronic cough in adults and children. Eur Respir J 55:58

Article  Google Scholar 

Canning BJ (2009) Central regulation of the cough reflex: therapeutic implications. Pulm Pharmacol Ther 22:75–81

Article  PubMed  PubMed Central  CAS  Google Scholar 

Niimi A, Matsumoto H, Ueda T, Takemura M, Suzuki K, Tanaka E, Chin K, Mishima M, Amitani R (2003) Impaired cough reflex in patients with recurrent pneumonia. Thorax 58:152–153

Article  PubMed  PubMed Central  CAS  Google Scholar 

Chung KF, McGarvey L, Song WJ, Chang AB, Lai K, Canning BJ, Birring SS, Smith JA, Mazzone SB (2022) Cough hypersensitivity and chronic cough. Nat Rev Dis Primers 8:45

Article  PubMed  PubMed Central  Google Scholar 

Belvisi MG, Birrell MA, Khalid S, Wortley MA, Dockry R, Coote J, Holt K, Dubuis E, Kelsall A, Maher SA, Bonvini S, Woodcock A, Smith JA (2016) Neurophenotypes in airway diseases. insights from translational cough studies. Am J Respir Crit Care Med 193:1364–1372

Article  PubMed  PubMed Central  CAS  Google Scholar 

Coleridge JC, Coleridge HM (1984) Afferent vagal C fibre innervation of the lungs and airways and its functional significance. Rev Physiol Biochem Pharmacol 99:1–110

PubMed  CAS  Google Scholar 

Undem BJ, Chuaychoo B, Lee MG, Weinreich D, Myers AC, Kollarik M (2004) Subtypes of vagal afferent C-fibres in guinea-pig lungs. J Physiol 556:905–917

Article  PubMed  PubMed Central  CAS  Google Scholar 

Ricco MM, Kummer W, Biglari B, Myers AC, Undem BJ (1996) Interganglionic segregation of distinct vagal afferent fibre phenotypes in guinea-pig airways. J Physiol 496(Pt 2):521–530

Article  PubMed  PubMed Central  Google Scholar 

Baker CV, Schlosser G (2005) The evolutionary origin of neural crest and placodes. J Exp Zool B 304:269–273

Article  Google Scholar 

Wine JJ (2007) Parasympathetic control of airway submucosal glands: central reflexes and the airway intrinsic nervous system. Auton Neurosci 133:35–54

Article  PubMed  PubMed Central  Google Scholar 

Coleridge HM, Coleridge JC (1994) Neural regulation of bronchial blood flow. Respir Physiol 98:1–13

Article  PubMed  CAS  Google Scholar 

Canning BJ (1985) Reflex regulation of airway smooth muscle tone. J Appl Physiol 2006(101):971–985

Google Scholar 

Canning BJ, Mazzone SB, Meeker SN, Mori N, Reynolds SM, Undem BJ (2004) Identification of the tracheal and laryngeal afferent neurones mediating cough in anaesthetized guinea-pigs. J Physiol 557:543–558

Article  PubMed  PubMed Central  CAS  Google Scholar 

Canning BJ, Farmer DG, Mori N (2006) Mechanistic studies of acid-evoked coughing in anesthetized guinea pigs. Am J Physiol Regul Integr Comp Physiol 291:R454-463

Article  PubMed  CAS  Google Scholar 

Caterina MJ, Schumacher MA, Tominaga M, Rosen TA, Levine JD, Julius D (1997) The capsaicin receptor: a heat-activated ion channel in the pain pathway. Nature 389:816–824

Article  PubMed  CAS  Google Scholar 

Ho CY, Gu Q, Lin YS, Lee LY (2001) Sensitivity of vagal afferent endings to chemical irritants in the rat lung. Respir Physiol 127:113–124

Article  PubMed  CAS  Google Scholar 

Widdicombe J (2001) Airway receptors. Respir Physiol 125:3–15

Article  PubMed  CAS  Google Scholar 

Kajekar R, Proud D, Myers AC, Meeker SN, Undem BJ (1999) Characterization of vagal afferent subtypes stimulated by bradykinin in guinea pig trachea. J Pharmacol Exp Ther 289:682–687

PubMed  CAS  Google Scholar 

Taylor-Clark TE (2021) Molecular identity, anatomy, gene expression and function of neural crest vs placode-derived nociceptors in the lower airways. Neurosci Lett 742:135505

Article  PubMed  CAS  Google Scholar 

Kubin L, Alheid GF, Zuperku EJ, McCrimmon DR (1985) Central pathways of pulmonary and lower airway vagal afferents. J Appl Physiol 2006(101):618–627

Google Scholar 

Driessen AK, Farrell MJ, Mazzone SB, McGovern AE (2015) The role of the paratrigeminal nucleus in vagal afferent evoked respiratory reflexes: a neuroanatomical and functional study in guinea pigs. Front Physiol 6:378

Article  PubMed  PubMed Central  Google Scholar 

Fryer AD, Jacoby DB (1992) Function of pulmonary M2 muscarinic receptors in antigen-challenged guinea pigs is restored by heparin and poly-L-glutamate. J Clin Invest 90:2292–2298

Article  PubMed  PubMed Central  CAS  Google Scholar 

Kalia M, Mesulam MM (1980) Brain stem projections of sensory and motor components of the vagus complex in the cat: I. The cervical vagus and nodose ganglion. J Comp Neurol 193:435–465

Article  PubMed  CAS  Google Scholar 

Kalia M, Sullivan JM (1982) Brainstem projections of sensory and motor components of the vagus nerve in the rat. J Comp Neurol 211:248–265

Article  PubMed  CAS  Google Scholar 

Baker DG, McDonald DM, Basbaum CB, Mitchell RA (1986) The architecture of nerves and ganglia of the ferret trachea as revealed by acetylcholinesterase histochemistry. J Comp Neurol 246:513–526

Article  PubMed  CAS  Google Scholar 

Dey RD, Altemus JB, Rodd A, Mayer B, Said SI, Coburn RF (1996) Neurochemical characterization of intrinsic neurons in ferret tracheal plexus. Am J Respir Cell Mol Biol 14:207–216

Article  PubMed  CAS  Google Scholar 

Fung DC, Beacock DJ, Richardson PS (1992) Vagal control of mucus glycoconjugate secretion into the feline trachea. J Physiol 453:435–447

Article  PubMed  PubMed Central  CAS  Google Scholar 

Dey RD, Satterfield B, Altemus JB (1999) Innervation of tracheal epithelium and smooth muscle by neurons in airway ganglia. Anat Rec 254:166–172

Article  PubMed  CAS  Google Scholar 

Costello RW, Schofield BH, Kephart GM, Gleich GJ, Jacoby DB, Fryer AD (1997) Localization of eosinophils to airway nerves and effect on neuronal M2 muscarinic receptor function. Am J Physiol 273:L93-103

PubMed  CAS  Google Scholar 

Elbon CL, Jacoby DB, Fryer AD (1995) Pretreatment with an antibody to interleukin-5 prevents loss of pulmonary M2 muscarinic receptor function in antigen-challenged guinea pigs. Am J Respir Cell Mol Biol 12:320–328

Article  PubMed  CAS  Google Scholar 

Evans CM, Fryer AD, Jacoby DB, Gleich GJ, Costello RW (1997) Pretreatment with antibody to eosinophil major basic protein prevents hyperresponsiveness by protecting neuronal M2 muscarinic receptors in antigen-challenged guinea pigs. J Clin Invest 100:2254–2262

Article  PubMed  PubMed Central  CAS  Google Scholar 

Fryer AD, Jacoby DB (1991) Parainfluenza virus infection damages inhibitory M2 muscarinic receptors on pulmonary parasympathetic nerves in the guinea-pig. Br J Pharmacol 102:267–271

Article  PubMed  PubMed Central  CAS  Google Scholar 

Fryer AD, Yarkony KA, Jacoby DB (1994) The effect of leukocyte depletion on pulmonary M2 muscarinic receptor function in parainfluenza virus-infected guinea-pigs. Br J Pharmacol 112:588–594

Article  PubMed  PubMed Central  CAS  Google Scholar 

Schultheis AH, Bassett DJ, Fryer AD (1985) Ozone-induced airway hyperresponsiveness and loss of neuronal M2 muscarinic receptor function. J Appl Physiol 1994(76):1088–1097

Google Scholar 

Costello RW, Evans CM, Yost BL, Belmonte KE, Gleich GJ, Jacoby DB, Fryer AD (1999) Antigen-induced hyperreactivity to histamine: role of the vagus nerves and eosinophils. Am J Physiol 276:L709-714

PubMed  CAS  Google Scholar 

Wagner EM, Jacoby DB (1985) Methacholine causes reflex bronchoconstriction. J Appl Physiol 1999(86):294–297

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