Single-cell transcriptomic analysis reveals transcriptional and cell subpopulation differences between human and pig immune cells

Arnon TI, Cyster JG (2014) Blood, sphingosine-1-phosphate and lymphocyte migration dynamics in the spleen. Curr Top Microbiol Immunol 378:107–128. https://doi.org/10.1007/978-3-319-05879-5_5

Article  CAS  PubMed  Google Scholar 

Auray G et al (2016) Characterization and transcriptomic analysis of porcine blood conventional and plasmacytoid dendritic cells reveals striking species-specific differences. J Immunol 197:4791–4806. https://doi.org/10.4049/jimmunol.1600672

Article  CAS  PubMed  Google Scholar 

Barnett BE et al (2016) Cutting edge: B cell-intrinsic T-bet expression is required to control chronic viral infection. J Immunol 197:1017–1022. https://doi.org/10.4049/jimmunol.1500368

Article  CAS  PubMed  Google Scholar 

Bianchi AT, van der Heijden PJ (1994) Antigen presenting cells and B-cells in the pig. Vet Immunol Immunopathol 43:63–68. https://doi.org/10.1016/0165-2427(94)90121-x

Article  CAS  PubMed  Google Scholar 

Binns RM, Duncan IA, Powis SJ, Hutchings A, Butcher GW (1992) Subsets of null and gamma delta T-cell receptor+ T lymphocytes in the blood of young pigs identified by specific monoclonal antibodies. Immunology 77:219–227

CAS  PubMed  PubMed Central  Google Scholar 

Boettcher AN, Loving CL, Cunnick JE, Tuggle CK (2018) Development of severe combined immunodeficient (SCID) pig models for translational cancer modeling: future insights on how humanized SCID pigs can improve preclinical cancer research. Front Oncol 8:559. https://doi.org/10.3389/fonc.2018.00559

Article  PubMed  PubMed Central  Google Scholar 

Bu D et al (2021) KOBAS-i: intelligent prioritization and exploratory visualization of biological functions for gene enrichment analysis. Nucleic Acids Res 49:W317–W325. https://doi.org/10.1093/nar/gkab447

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cencioni MT, Ali R, Nicholas R, Muraro PA (2021) Defective CD19+CD24(hi)CD38(hi) transitional B-cell function in patients with relapsing-remitting MS. Mult Scler 27:1187–1197. https://doi.org/10.1177/1352458520951536

Article  CAS  PubMed  Google Scholar 

Charerntantanakul W, Roth JA (2006) Biology of porcine T lymphocytes. Anim Health Res Rev 7:81–96. https://doi.org/10.1017/S1466252307001235

Article  PubMed  Google Scholar 

Chen Q et al (2020) CD19(+)CD24(hi)CD38(hi) B cell dysfunction in primary biliary cholangitis. Mediat Inflamm 2020:3019378. https://doi.org/10.1155/2020/3019378

Article  CAS  Google Scholar 

Cizkova J et al (2019) The role of αβ T-cells in spontaneous regression of melanoma tumors in swine. Dev Comp Immunol 92:60–68. https://doi.org/10.1016/j.dci.2018.10.001

Article  CAS  PubMed  Google Scholar 

Cooper DKC (2021) Genetically engineered pig kidney transplantation in a brain-dead human subject. Xenotransplantation 28:e12718. https://doi.org/10.1111/xen.12718

Article  PubMed  PubMed Central  Google Scholar 

Cooper DKC, Hara H (2021) “You cannot stay in the laboratory forever”*: taking pig kidney xenotransplantation from the laboratory to the clinic. EBioMedicine 71:103562. https://doi.org/10.1016/j.ebiom.2021.103562

Article  PubMed  PubMed Central  Google Scholar 

Cooper DK, Gollackner B, Sachs DH (2002) Will the pig solve the transplantation backlog? Annu Rev Med 53:133–147. https://doi.org/10.1146/annurev.med.53.082901.103900

Article  CAS  PubMed  Google Scholar 

Cooper DKC, Ekser B, Tector AJ (2015) A brief history of clinical xenotransplantation. Int J Surg 23:205–210. https://doi.org/10.1016/j.ijsu.2015.06.060

Article  PubMed  PubMed Central  Google Scholar 

Cooper DKC et al (2018) Xenotransplantation-the current status and prospects. Br Med Bull 125:5–14. https://doi.org/10.1093/bmb/ldx043

Article  CAS  PubMed  Google Scholar 

Cooper DKC et al (2021) Pig kidney xenotransplantation: progress toward clinical trials. Clin Transplant 35:e14139. https://doi.org/10.1111/ctr.14139

Article  PubMed  Google Scholar 

Cowan PJ, Hawthorne WJ, Nottle MB (2019) Xenogeneic transplantation and tolerance in the era of CRISPR-Cas9. Curr Opin Organ Transplant 24:5–11. https://doi.org/10.1097/MOT.0000000000000589

Article  CAS  PubMed  Google Scholar 

Cukrowska B et al (1996) Isotype and antibody specificity of spontaneously formed immunoglobulins in pig fetuses and germ-free piglets: production by CD5-B cells. Immunology 88:611–617. https://doi.org/10.1046/j.1365-2567.1996.d01-699.x

Article  CAS  PubMed  PubMed Central  Google Scholar 

Dasgupta S, Dasgupta S, Bandyopadhyay M (2020) Regulatory B cells in infection, inflammation, and autoimmunity. Cell Immunol 352:104076. https://doi.org/10.1016/j.cellimm.2020.104076

Article  CAS  PubMed  Google Scholar 

Deng A et al (2005) Granulysin, a cytolytic molecule, is also a chemoattractant and proinflammatory activator. J Immunol 174:5243–5248. https://doi.org/10.4049/jimmunol.174.9.5243

Article  CAS  PubMed  Google Scholar 

Dutt S et al (2007) Naive and memory T cells induce different types of graft-versus-host disease. J Immunol 179:6547–6554. https://doi.org/10.4049/jimmunol.179.10.6547

Article  CAS  PubMed  Google Scholar 

Fairbairn L et al (2013) Comparative analysis of monocyte subsets in the pig. J Immunol 190:6389–6396. https://doi.org/10.4049/jimmunol.1300365

Article  CAS  PubMed  Google Scholar 

Guerra-Maupome M, McGill JL (2019) Characterization of local and circulating bovine γδ T cell responses to respiratory BCG vaccination. Sci Rep 9:15996. https://doi.org/10.1038/s41598-019-52565-z

Article  CAS  PubMed  PubMed Central  Google Scholar 

Herrera-Uribe J et al (2021) Reference transcriptomes of porcine peripheral immune cells created through bulk and single-cell RNA sequencing. Front Genet 12:689406. https://doi.org/10.3389/fgene.2021.689406

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hryhorowicz M, Zeyland J, Słomski R, Lipiński D (2017) Genetically modified pigs as organ donors for xenotransplantation. Mol Biotechnol 59:435–444. https://doi.org/10.1007/s12033-017-0024-9

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kanawa M et al (2021) The identification of marker genes for predicting the osteogenic differentiation potential of mesenchymal stromal cells. Curr Issues Mol Biol 43:2157–2166. https://doi.org/10.3390/cimb43030150

Article  CAS  PubMed  PubMed Central  Google Scholar 

Knox JJ, Myles A, Cancro MP (2019) T-bet(+) memory B cells: generation, function, and fate. Immunol Rev 288:149–160. https://doi.org/10.1111/imr.12736

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kop EN et al (2009) Differential expression of CD97 on human lymphocyte subsets and limited effect of CD97 antibodies on allogeneic T-cell stimulation. Immunol Lett 123:160–168. https://doi.org/10.1016/j.imlet.2009.03.009

Article  CAS  PubMed  Google Scholar 

Kuehn BM (2022) First pig-to-human heart transplant marks a milestone in xenotransplantation. Circulation 145:1870–1871. https://doi.org/10.1161/CIRCULATIONAHA.122.060418

Article  PubMed  Google Scholar 

Lagumdzic E et al (2022) Transcriptome profiling of porcine naïve, intermediate and terminally differentiated CD8(+) T cells. Front Immunol 13:849922. https://doi.org/10.3389/fimmu.2022.849922

Article  CAS  PubMed  PubMed Central  Google Scholar 

Le Page L, Baldwin CL, Telfer JC (2022) γδ T cells in artiodactyls: focus on swine. Dev Comp Immunol 128:104334. https://doi.org/10.1016/j.dci.2021.104334

Article  CAS  PubMed  Google Scholar 

Lexer G et al (1986) Hyperacute rejection in a discordant (pig to baboon) cardiac xenograft model. J Heart Transplant 5:411–418

CAS  PubMed  Google Scholar 

Li HW et al (2017) Impact of mixed xenogeneic porcine hematopoietic chimerism on human NK cell recognition in a humanized mouse model. Am J Transplant 17:353–364. https://doi.org/10.1111/ajt.13957

Article  CAS  PubMed  Google Scholar 

Liu S, Trapnell C (2016) Single-cell transcriptome sequencing: recent advances and remaining challenges. F1000Res. https://doi.org/10.12688/f1000research.7223.1

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