Clinico-pathological characteristics of IGFR1 and VEGF-A co-expression in early and locally advanced-stage lung adenocarcinoma

Ahlen J, Wejde J, Brosjo O et al (2005) Insulin-like growth factor type 1 receptor expression correlates to good prognosis in highly malignant soft tissue sarcoma. Clin Cancer Res 11:206–216

Article  CAS  PubMed  Google Scholar 

Alyoussef A (2021) The therapeutic effects of blocking IGF-R1 on mice model of skin cancer. J Dermatolog Treat 32:803–811. https://doi.org/10.1080/09546634.2019.1708243

Article  CAS  PubMed  Google Scholar 

Cappuzzo F, Toschi L, Tallini G et al (2006) Insulin-like growth factor receptor 1 (IGFR-1) is significantly associated with longer survival in non-small-cell lung cancer patients treated with gefitinib. Ann Oncol 17:1120–1127. https://doi.org/10.1093/annonc/mdl077

Article  CAS  PubMed  Google Scholar 

Chen J, Liu BX, Shen Q et al (2020) Limonin inhibits angiogenesis and metastasis of human breast cancer cells by suppressing the VEGFR2/IGFR1-mediated STAT3 signaling pathway. Transl Cancer Res. https://doi.org/10.21037/tcr-20-1992

Article  PubMed  PubMed Central  Google Scholar 

Claesson-Welsh L, Welsh M (2013) VEGFA and tumour angiogenesis. J Intern Med. https://doi.org/10.1111/joim.12019

Article  PubMed  Google Scholar 

Dufourny B, Alblas J, Van Teeffelen HA et al (1997) Mitogenic signaling of insulin-like growth factor I in MCF-7 human breast cancer cells requires phosphatidylinositol 3-kinase and is independent of mitogen-activated protein kinase. J Biol Chem 272:31163–31171. https://doi.org/10.1074/jbc.272.49.31163

Article  CAS  PubMed  Google Scholar 

Gariboldi MB, Ravizza R, Monti E (2010) The IGFR1 inhibitor NVP-AEW541 disrupts a pro-survival and pro-angiogenic IGF-STAT3-HIF1 pathway in human glioblastoma cells. Biochem Pharmacol 80:455–462. https://doi.org/10.1016/j.bcp.2010.05.011

Article  CAS  PubMed  Google Scholar 

Golestan S, Soltani BM, Jafarzadeh M et al (2023) LINC02381 suppresses cell proliferation and promotes apoptosis via attenuating IGF1R/PI3K/AKT signaling pathway in breast cancer. Funct Integr Genomics 23:40. https://doi.org/10.1007/s10142-023-00965-w

Article  CAS  PubMed  Google Scholar 

Jenkins R, Walker J, Roy UB (2023) 2022 cancer statistics: Focus on lung cancer. Future Oncol. https://doi.org/10.2217/fon-2022-1214

Article  PubMed  Google Scholar 

Joehlin-Price AS, Stephens JA, Zhang J et al (2016) Endometrial cancer insulin-like growth factor 1 receptor (IGF1R) expression increases with body mass index and is associated with pathologic extent and prognosis. Cancer Epidemiol Biomarkers Prev 25:438–445. https://doi.org/10.1158/1055-9965.EPI-15-1145

Article  CAS  PubMed  Google Scholar 

Khandwala HM, Mccutcheon IE, Flyvbjerg A et al (2000) The effects of insulin-like growth factors on tumorigenesis and neoplastic growth. Endocr Rev 21:215–244. https://doi.org/10.1210/edrv.21.3.0399

Article  CAS  PubMed  Google Scholar 

Liu S, Qin T, Jia Y et al (2019) PD-L1 expression Is associated With VEGFA and LADC patients’ survival. Front Oncol 9:189. https://doi.org/10.3389/fonc.2019.00189

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ludovini V, Bellezza G, Pistola L et al (2009) High coexpression of both insulin-like growth factor receptor-1 (IGFR-1) and epidermal growth factor receptor (EGFR) is associated with shorter disease-free survival in resected non-small-cell lung cancer patients. Ann Oncol 20:842–849. https://doi.org/10.1093/annonc/mdn727

Article  CAS  PubMed  Google Scholar 

Mathur RS, Mathur SP (2005) Vascular endothelial growth factor (VEGF) up-regulates epidermal growth factor receptor (EGF-R) in cervical cancer in vitro: this action is mediated through HPV-E6 in HPV-positive cancers. Gynecol Oncol 97:206–213. https://doi.org/10.1016/j.ygyno.2004.12.011

Article  CAS  PubMed  Google Scholar 

Mehta S, Fiorelli R, Bao X et al (2022) A phase 0 trial of Ceritinib in patients with brain metastases and recurrent glioblastoma. Clin Cancer Res 28:289–297. https://doi.org/10.1158/1078-0432.CCR-21-1096

Article  CAS  PubMed  PubMed Central  Google Scholar 

Micke P, JS Mattsson, D Djureinovic, et al (2016) The Impact of the Fourth Edition of the WHO Classification of Lung Tumours on Histological Classification of Resected Pulmonary NSCCs. J Thorac Oncol https://doi.org/10.1016/j.jtho.2016.01.020.

Osmani L, Askin F, Gabrielson E et al (2018) Current WHO guidelines and the critical role of immunohistochemical markers in the subclassification of non-small cell lung carcinoma (NSCLC): Moving from targeted therapy to immunotherapy. Semin Cancer Biol 52:103–109. https://doi.org/10.1016/j.semcancer.2017.11.019

Article  CAS  PubMed  Google Scholar 

Park E, Park SY, Kim H et al (2015) Membranous Insulin-like growth factor-1 receptor (IGF1R) expression Is predictive of poor prognosis in patients with epidermal growth factor receptor (EGFR)-mutant lung adenocarcinoma. J Pathol Transl Med. https://doi.org/10.4132/jptm.2015.07.10

Article  PubMed  PubMed Central  Google Scholar 

Qin T, Xia J, Liu S et al (2020) Clinical importance of VEGFC and PD-L1 co-expression in lung adenocarcinoma patients. Thorac Cancer 11:1139–1148. https://doi.org/10.1111/1759-7714.13354

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ramanathan R, Olex AL, Dozmorov M et al (2017) Angiopoietin pathway gene expression associated with poor breast cancer survival. Breast Cancer Res Treat 162:191–198. https://doi.org/10.1007/s10549-017-4102-2

Article  CAS  PubMed  PubMed Central  Google Scholar 

Reinmuth N, Jauch A, Xu EC et al (2008) Correlation of EGFR mutations with chromosomal alterations and expression of EGFR, ErbB3 and VEGF in tumor samples of lung adenocarcinoma patients. Lung Cancer. https://doi.org/10.1016/j.lungcan.2008.03.011

Article  PubMed  Google Scholar 

Rocha RL, Hilsenbeck SG, Jackson JG et al (1997) Insulin-like growth factor binding protein-3 and insulin receptor substrate-1 in breast cancer: correlation with clinical parameters and disease-free survival. Clin Cancer Res 3:103–109

CAS  PubMed  Google Scholar 

Da Cunha Santos G, Shepherd FA, Tsao MS (2011) EGFR mutations and lung cancer. Annu Rev Pathol 6:49–69. https://doi.org/10.1146/annurev-pathol-011110-130206

Article  CAS  Google Scholar 

Sharma R (2022) Mapping of global, regional and national incidence, mortality and mortality-to-incidence ratio of lung cancer in 2020 and 2050. Int J Clin Oncol. https://doi.org/10.1007/s10147-021-02108-2

Article  PubMed  PubMed Central  Google Scholar 

Siegel RL, Miller KD, Wagle NS et al (2023) Cancer statistics, 2023. CA Cancer J Clin. https://doi.org/10.3322/caac.21763

Article  PubMed  Google Scholar 

Takahashi N, Iwasa S, Taniguchi H et al (2016) Prognostic role of ERBB2, MET and VEGFA expression in metastatic colorectal cancer patients treated with anti-EGFR antibodies. Br J Cancer 114:1003–1011. https://doi.org/10.1038/bjc.2016.74

Article  CAS  PubMed  PubMed Central  Google Scholar 

Turner BC, Haffty BG, Narayanan L et al (1997) Insulin-like growth factor-I receptor overexpression mediates cellular radioresistance and local breast cancer recurrence after lumpectomy and radiation. Cancer Res 57:3079–3083

CAS  PubMed  Google Scholar 

Wang X, Chen L, Zhao X et al (2020) A cathelicidin-related antimicrobial peptide suppresses cardiac hypertrophy induced by pressure overload by regulating IGFR1/PI3K/AKT and TLR9/AMPKalpha. Cell Death Dis 11:96. https://doi.org/10.1038/s41419-020-2296-4

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wang P, Mak VC, Cheung LW (2023) Drugging IGF-1R in cancer: new insights and emerging opportunities. Genes Dis 10:199–211. https://doi.org/10.1016/j.gendis.2022.03.002

Article  CAS  PubMed  Google Scholar 

留言 (0)

沒有登入
gif