Photoactivated chromophore-corneal cross-linking accelerates corneal healing in fungal keratitis: an updated meta-analysis

Maria C-A, Pauline K. Watson Stephanie L, Infectious keratitis: a review. Clin Exp Ophthalmol. 2022;50:543–62.

Article  Google Scholar 

Ting DSJ, Ho CS, Deshmukh R, et al. Infectious keratitis: an update on epidemiology, causative microorganisms, risk factors, and antimicrobial resistance. Eye (Lond). 2021;35:1084–101.

Article  PubMed  Google Scholar 

Fiona S. The epidemiology of infectious keratitis. Ocul Surf. 2023;28:351–63.

Article  Google Scholar 

Collier Sarah A, Gronostaj Michael P, MacGurn Amanda K, et al. Estimated burden of keratitis–United States, 2010. MMWR Morb Mortal Wkly Rep. 2014;63:1027–30.

CAS  PubMed  PubMed Central  Google Scholar 

Hoffman JJ, Burton MJ, Leck A. Mycotic keratitis- a global threat from the filamentous fungi. J Fungi. 2021;7:273.

Article  Google Scholar 

Hafezi F, Randleman JB. PACK-CXL: defining CXL for infectious keratitis. J Refract Surg. 2014;30:438–9.

Article  PubMed  Google Scholar 

Ting DSJ, Henein C, Said DG, Dua HS. Photoactivated chromophore for infectious keratitis–corneal cross-linking (PACK-CXL): a systematic review and meta-analysis. Ocul Surf. 2019;17:624–34.

Article  PubMed  Google Scholar 

Papaioannou L, Miligkos M, Papathanassiou M. Corneal collagen cross-linking for infectious keratitis: a systematic review and meta-analysis. Cornea. 2016;35:62–71.

Article  PubMed  Google Scholar 

Davis S, Bovelle R, Han G, Kwagyan J. Corneal collagen cross-linking for bacterial infectious keratitis. The Cochrane Database of Systematic Reviews. 2020;6:CD013001–CD013001.

PubMed  Google Scholar 

Raj N, Vanathi M, Ahmed NH. et al. Recent perspectives in the management of fungal keratitis. J Fungi Basel. 2021;7:undefined.

Wei A, Wang K, Wang Y, Gong L, Xu J, Shao T. Evaluation of corneal cross-linking as adjuvant therapy for the management of fungal keratitis. Graefes Arch Clin Exp Ophthalmol. 2019;257:1443–52.

Article  PubMed  Google Scholar 

Prajna NV, Radhakrishnan N, Lalitha P, Austin A, Ray KJ, Keenan JD, et al. Cross-linking–assisted infection reduction: a randomized clinical trial evaluating the effect of adjuvant cross-linking on outcomes in fungal keratitis. Ophthalmology. 2020;127:159–66.

Article  PubMed  Google Scholar 

Jeyalatha Mani V, Parthasarathy D, Padmanabhan P, Narayanan N, Lakshmipathy M, Pachayappan SK, et al. Therapeutic effect of corneal crosslinking on fungal keratitis: efficacy of corneal collagen crosslinking as an adjuvant therapy for fungal keratitis in a tertiary eye hospital in South India. Ocul Immunol Inflamm. 2021;29:1648–55.

Article  CAS  PubMed  Google Scholar 

Prajna NV, Radhakrishnan N, Lalitha P, et al. Cross-linking assisted infection reduction (CLAIR): a randomized clinical trial evaluating the effect of adjuvant cross-linking on bacterial keratitis. Cornea. 2021;40:837–41.

Article  PubMed  Google Scholar 

Cumpston M, Li T, Page MJ, et al. Updated guidance for trusted systematic reviews: a new edition of the Cochrane Handbook for Systematic Reviews of Interventions. Cochrane Database Syst Rev. 2019;10:ED000142.

PubMed  Google Scholar 

Moher D, Liberati A, Tetzlaff J, Altman DG, Group* P. Preferred Reporting Items for Systematic Reviews and Meta-Analyses: the PRISMA statement. Ann Intern Med. 2009;151:264–9.

Article  PubMed  Google Scholar 

Higgins J, Altman DG, Gøtzsche PC, Jüni P, Moher D, Oxman AD, et al. The Cochrane Collaboration’s tool for assessing risk of bias in randomised trials. BMJ. 2011;343:d5928.

Article  PubMed  PubMed Central  Google Scholar 

Gu W-J, Wei C-Y, Yin R-X. Lack of efficacy of probiotics in preventing ventilator-associated pneumonia. Chest. 2012;142:859–68.

Article  PubMed  Google Scholar 

Higgins JP, Thompson SG, Deeks JJ, Altman DG. Measuring inconsistency in meta-analyses. BMJ. 2003;327:557–60.

Article  PubMed  PubMed Central  Google Scholar 

Guyatt GH, Oxman AD, Vist GE, Kunz R, Falck-Ytter Y, Alonso-Coello P, et al. GRADE: an emerging consensus on rating quality of evidence and strength of recommendations. BMJ. 2008;336:924–6.

Article  PubMed  PubMed Central  Google Scholar 

Rose-Nussbaumer J, Austin A, Porco TC, Prajna V, Naveen R. Cross-linking assisted infection reduction: a randomized clinical trial (CLAIR). Invest Ophthalmol Visual Sci. 2019;60:2222.

Google Scholar 

Aguilar LP, Jimenez-Corona A, Sanchez-Huerta V, Lichtinger A, Hernandez-Quintela E, Graue-Hernandez EO. The efficacy and safety of accelerated collagen crosslinking (CXL) for infectious keratitis: a randomized clinical trial. Invest Ophthalmol Visual Sci. 2018;59:1570.

Google Scholar 

Dua HS, Said DG. Corneal collagen cross linking: crossing out the microbes. J EuCornea. 2019;3:22–3.

Article  Google Scholar 

Copeland RA Jr, Davis SA, Lee YJ, Kwagyan J, Bovelle R. Corneal collagen cross-linking for infectious keratitis. Cochrane Database Syst Rev. 2018;2018:CD03001.

Google Scholar 

Makdoumi K, Mortensen J, Sorkhabi O, Malmvall B-E, Crafoord S. UVA-riboflavin photochemical therapy of bacterial keratitis: a pilot study. Graefes Arch Clin Exp Ophthalmol. 2012;250:95–102.

Article  CAS  PubMed  Google Scholar 

Price MO, Tenkman LR, Schrier A, Fairchild KM, Trokel SL, Price FW Jr. Photoactivated riboflavin treatment of infectious keratitis using collagen cross-linking technology. J Refract Surg. 2012;28:706–13.

Article  PubMed  Google Scholar 

Erdem E, Harbiyeli II, Boral H, Ilkit M, Yagmur M, Ersoz R. Corneal collagen cross-linking for the management of mycotic keratitis. Mycopathologia. 2018;183:521–7.

Article  CAS  PubMed  Google Scholar 

Said DG, Elalfy MS, Gatzioufas Z, El-Zakzouk ES, Hassan MA, Saif MY, et al. Collagen cross-linking with photoactivated riboflavin (PACK-CXL) for the treatment of advanced infectious keratitis with corneal melting. Ophthalmology. 2014;121:1377–82.

Article  PubMed  Google Scholar 

Olivier R, Johnny M, Farhad H, et al. Corneal cross-linking as an adjuvant therapy in the management of recalcitrant deep stromal fungal keratitis: a randomized trial. Am J Ophthalmol. 2015;160:616–7.

Article  Google Scholar 

Farhad H, Sabine K. Photoactivated chromophore for moderate to severe infectious keratitis as an adjunct therapy: a randomized controlled trial. Am J Ophthalmol. 2016;168:293–4.

Article  Google Scholar 

Prajna NV, Radhakrishnan N, Lalitha P, Austin A, Liu Z, Keenan JD, et al. Cross-linking assisted infection reduction: one-year follow-up of a randomized clinical trial evaluating cross-linking for fungal keratitis. Ophthalmology. 2021;128:950–2.

Article  PubMed  Google Scholar 

Prajna NV, Radhakrishnan N, Lalitha P, Liu Z, Keenan JD, Arnold BF, Rose-Nussbaumer J. Mediators of the effect of corneal cross-linking on visual acuity for fungal ulcers: a prespecified secondary analysis from the cross-linking-assisted infection reduction trial. Cornea. 2022;41(10):1217–21.

Article  PubMed  Google Scholar 

Hafezi F, Hosny M, Shetty R, et al. PACK-CXL vs antimicrobial therapy for bacterial, fungal, and mixed infectious keratitis: a prospective randomized phase 3 trial. Eye Vis (Lond). 2022;9:2.

Article  PubMed  Google Scholar 

Bamdad S, Malekhosseini H, Khosravi A. Ultraviolet A/riboflavin collagen cross-linking for treatment of moderate bacterial corneal ulcers. Cornea. 2015;34:402–6.

Article  PubMed  Google Scholar 

Uddaraju M, Mascarenhas J, Das MR, Radhakrishnan N, Keenan JD, Prajna L, et al. Corneal cross-linking as an adjuvant therapy in the management of recalcitrant deep stromal fungal keratitis: a randomized trial. Am J Ophthalmol. 2015;160(131–134):e135.

Google Scholar 

Kasetsuwan N, Reinprayoon U, Satitpitakul V. Photoactivated chromophore for moderate to severe infectious keratitis as an adjunct therapy: a randomized controlled trial. Am J Ophthalmol. 2016;165:94–9.

Article  CAS  PubMed  Google Scholar 

Vazirani J, Vaddavalli PK. Cross-linking for microbial keratitis. Indian J Ophthalmol. 2013;61:441.

Article  PubMed  PubMed Central  Google Scholar 

Vajpayee RB, Shafi SN, Maharana PK, Sharma N, Jhanji V. Evaluation of corneal collagen cross-linking as an additional therapy in mycotic keratitis. Clin Experiment Ophthalmol. 2015;43:103–7.

Article  PubMed  Google Scholar 

Bonzano C, Di Zazzo A, Barabino S, Coco G, Traverso CE. Collagen cross-linking in the management of microbial keratitis. Ocul Immunol Inflamm. 2019;27:507–12.

Article  CAS  PubMed  Google Scholar 

Bamdad S, Khalili MR, Khosravi A, Attarzade A, Movahedan H, Nejabat M. Corneal cross-linking as an adjunct for the management of refractory fungal keratitis. Middle East Afr J Ophthalmol. 2020;27:204.

Article  PubMed  Google Scholar 

Basaiawmoit P, Selvin SST, Korah S. PACK-CXL in reducing the time to heal in suppurative corneal ulcers: observations of a pilot study from South India. Cornea. 2018;37:1376–80.

Article  PubMed  Google Scholar 

Thakur A, Gupta A, Handa S. Application of photoactivated chromophore for infectious keratitis-corneal collagen crosslinking for fungal phaco-tunnel infection. Indian J Ophthalmol. 2019;67:1700.

Article  PubMed  PubMed Central  Google Scholar 

Richoz O, Kling S, Hoogewoud F, Hammer A, Tabibian D, Francois P, et al. Antibacterial efficacy of accelerated photoactivated chromophore for keratitis–corneal collagen cross-linking (PACK-CXL). J Refract Surg. 2014;30:850–4.

Article  PubMed  Google Scholar 

留言 (0)

沒有登入
gif