Genetic hypogonadal mouse model reveals niche-specific influence of reproductive axis and sex on intestinal microbial communities

Shepherd R, Cheung AS, Pang K, Saffery R, Novakovic B. Sexual dimorphism in innate immunity: the role of sex hormones and epigenetics. Front Immunol. 2021. https://doi.org/10.3389/fimmu.2020.604000.

Article  PubMed  PubMed Central  Google Scholar 

Spaziani M, Tarantino C, Tahani N, Gianfrilli D, Sbardella E, Lenzi A, et al. Hypothalamo-Pituitary axis and puberty. Mol Cell Endocrinol. 2021;520: 111094.

Article  CAS  PubMed  Google Scholar 

Vegeto E, Villa A, Della Torre S, Crippa V, Rusmini P, Cristofani R, et al. The role of sex and sex hormones in neurodegenerative diseases. Endocr Rev. 2020;41(2):273–319.

Article  PubMed  Google Scholar 

Xu L, Yuan Y, Che Z, Tan X, Wu B, Wang C, et al. The hepatoprotective and hepatotoxic roles of sex and sex-related hormones. Front Immunol. 2022;13: 939631.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Connelly PJ, Casey H, Montezano AC, Touyz RM, Delles C. Sex steroids receptors, hypertension, and vascular ageing. J Hum Hypertens. 2022;36(2):120–5.

Article  PubMed  Google Scholar 

Khosla S, Monroe DG. Regulation of bone metabolism by sex steroids. Cold Spring Harb Perspect Med. 2018. https://doi.org/10.1101/cshperspect.a031211.

Article  PubMed  PubMed Central  Google Scholar 

Dean AE, Reichardt F, Anakk S. Sex differences feed into nuclear receptor signaling along the digestive tract. Biochim Biophys Acta Mol Basis Dis. 2021;1867(11): 166211.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hayter SM, Cook MC. Updated assessment of the prevalence, spectrum and case definition of autoimmune disease. Autoimmun Rev. 2012;11(10):754–65.

Article  PubMed  Google Scholar 

Herzog D, Buehr P, Koller R, Rueger V, Heyland K, Nydegger A, et al. Gender differences in paediatric patients of the Swiss inflammatory bowel disease cohort study. Pediatr Gastroenterol Hepatol Nutr. 2014;17(3):147–54.

Article  PubMed  PubMed Central  Google Scholar 

van Hooff MH, Voorhorst FJ, Kaptein MB, Hirasing RA, Koppenaal C, Schoemaker J. Endocrine features of polycystic ovary syndrome in a random population sample of 14–16 year old adolescents. Hum Reprod. 1999;14(9):2223–9.

Article  PubMed  Google Scholar 

Yatsunenko T, Rey FE, Manary MJ, Trehan I, Dominguez-Bello MG, Contreras M, et al. Human gut microbiome viewed across age and geography. Nature. 2012;486(7402):222–7.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Yuan X, Chen R, Zhang Y, Lin X, Yang X. Sexual dimorphism of gut microbiota at different pubertal status. Microb Cell Fact. 2020;19(1):152.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Yuan X, Chen R, Zhang Y, Lin X, Yang X. Gut microbiota: effect of pubertal status. BMC Microbiol. 2020;20(1):334.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Korpela K, Kallio S, Salonen A, Hero M, Kukkonen AK, Miettinen PJ, et al. Gut microbiota develop towards an adult profile in a sex-specific manner during puberty. Sci Rep. 2021;11(1):23297.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Mueller S, Saunier K, Hanisch C, Norin E, Alm L, Midtvedt T, et al. Differences in fecal microbiota in different European study populations in relation to age, gender, and country: a cross-sectional study. Appl Environ Microbiol. 2006;72(2):1027–33.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Li M, Wang B, Zhang M, Rantalainen M, Wang S, Zhou H, et al. Symbiotic gut microbes modulate human metabolic phenotypes. Proc Natl Acad Sci. 2008;105(6):2117–22.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ding T, Schloss PD. Dynamics and associations of microbial community types across the human body. Nature. 2014;509(7500):357–60.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Dominianni C, Sinha R, Goedert JJ, Pei Z, Yang L, Hayes RB, et al. Sex, body mass index, and dietary fiber intake influence the human gut microbiome. PLoS ONE. 2015;10(4): e0124599-e.

Article  Google Scholar 

Gao X, Zhang M, Xue J, Huang J, Zhuang R, Zhou X, et al. Body mass index differences in the gut microbiota are gender specific. Front Microbiol. 2018;9:1250.

Article  PubMed  PubMed Central  Google Scholar 

Falony G, Joossens M, Vieira-Silva S, Wang J, Darzi Y, Faust K, et al. Population-level analysis of gut microbiome variation. Science. 2016;352(6285):560–4.

Article  CAS  PubMed  Google Scholar 

Santos-Marcos JA, Rangel-Zuñiga OA, Jimenez-Lucena R, Quintana-Navarro GM, Garcia-Carpintero S, Malagon MM, et al. Influence of gender and menopausal status on gut microbiota. Maturitas. 2018;116:43–53.

Article  PubMed  Google Scholar 

Borgo F, Garbossa S, Riva A, Severgnini M, Luigiano C, Benetti A, et al. Body mass index and sex affect diverse microbial niches within the gut. Front Microbiol. 2018. https://doi.org/10.3389/fmicb.2018.00213.

Article  PubMed  PubMed Central  Google Scholar 

Takagi T, Naito Y, Inoue R, Kashiwagi S, Uchiyama K, Mizushima K, et al. Differences in gut microbiota associated with age, sex, and stool consistency in healthy Japanese subjects. J Gastroenterol. 2019;54(1):53–63.

Article  PubMed  Google Scholar 

Cui M, Trimigno A, Aru V, Rasmussen MA, Khakimov B, Engelsen SB. Influence of age, sex, and diet on the human fecal metabolome investigated by (1)H NMR spectroscopy. J Proteome Res. 2021. https://doi.org/10.1021/acs.jproteome.1c00220.

Article  PubMed  Google Scholar 

Sinha T, Vich Vila A, Garmaeva S, Jankipersadsing SA, Imhann F, Collij V, et al. Analysis of 1135 gut metagenomes identifies sex-specific resistome profiles. Gut Microbes. 2019;10(3):358–66.

Article  CAS  PubMed  Google Scholar 

Mayneris-Perxachs J, Arnoriaga-Rodríguez M, Luque-Córdoba D, Priego-Capote F, Pérez-Brocal V, Moya A, et al. Gut microbiota steroid sexual dimorphism and its impact on gonadal steroids: influences of obesity and menopausal status. Microbiome. 2020;8(1):136.

Article  CAS  PubMed  PubMed Central  Google Scholar 

de la Cuesta-Zuluaga J, Kelley ST, Chen Y, Escobar JS, Mueller NT, Ley RE, et al. Age- and sex-dependent patterns of gut microbial diversity in human adults. mSystems. 2019;4(4): e00261-19.

Article  PubMed  PubMed Central  Google Scholar 

Peters BA, Lin J, Qi Q, Usyk M, Isasi CR, Mossavar-Rahmani Y, et al. Menopause is associated with an altered gut microbiome and estrobolome, with implications for adverse cardiometabolic risk in the Hispanic Community Health Study/Study of Latinos. mSystems. 2022;7(3):e00273-22.

Article  PubMed  PubMed Central  Google Scholar 

Markle JGM, Frank DN, Adeli K, von Bergen M, Danska JS. Microbiome manipulation modifies sex-specific risk for autoimmunity. Gut Microbes. 2014;5(4):485–93.

Article  PubMed  Google Scholar 

Yurkovetskiy L, Burrows M, Khan Aly A, Graham L, Volchkov P, Becker L, et al. Gender bias in autoimmunity is influenced by microbiota. Immunity. 2013;39(2):400–12.

Article  CAS  PubMed  Google Scholar 

Org E, Mehrabian M, Parks BW, Shipkova P, Liu X, Drake TA, et al. Sex differences and hormonal effects on gut microbiota composition in mice. Gut Microbes. 2016;7(4):313–22.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bridgewater LC, Zhang C, Wu Y, Hu W, Zhang Q, Wang J, et al. Gender-based differences in host behavior and gut microbiota composition in response to high fat diet and stress in a mouse model. Sci Rep. 2017;7(1):10776.

Article  PubMed  PubMed Central  Google Scholar 

Donaldson GP, Lee SM, Mazmanian SK. Gut biogeography of the bacterial microbiota. Nat Rev Microbiol. 2016;14(1):20–32.

Article  CAS  PubMed  Google Scholar 

Barlow JT, Bogatyrev SR, Ismagilov RF. A quantitative sequencing framework for absolute abundance measurements of mucosal and lumenal microbial communities. Nat Commun. 2020;11(1):2590.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Tropini C, Earle KA, Huang KC, Sonnenburg JL. The gut microbiome: connecting spatial organization to function. Cell Host Microbe. 2017;21(4):433–42.

Article  CAS  PubMed  PubMed Central  Google Scholar 

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