CREB1 Silencing Protects Against Inflammatory Response in Rats with Deep Vein Thrombosis Through Reducing RPL9 Expression and Blocking NF-κB Signaling

Wang TY, Sakamoto JT, Nayar G, Suresh V, Loriaux DB, Desai R, et al. Independent Predictors of 30-Day Perioperative Deep Vein Thrombosis in 1346 Consecutive Patients After Spine Surgery. World Neurosurg. 2015;84(6):1605–12.

Article  PubMed  Google Scholar 

Sforza M, Husein R, Saghir R, Saghir N, Okhiria R, Okhiria T, et al. Deep Vein Thrombosis (DVT) and Abdominoplasty: A Holistic 8-Point Protocol-Based Approach to Prevent DVT. Aesthet Surg J. 2021;41(10):Np1310-np20.

Article  PubMed  Google Scholar 

Sevuk U, Altindag R, Bahadir MV, Ay N, Demirtas E, Ayaz F. Value of platelet indices in identifying complete resolution of thrombus in deep venous thrombosis patients. Indian J Hematol Blood Trans : an official journal of Indian Society of Hematology and Blood Transfusion. 2015;31(1):71–6.

Article  Google Scholar 

Santin BJ, Lohr JM, Panke TW, Neville PM, Felinski MM, Kuhn BA, et al. Venous duplex and pathologic differences in thrombus characteristics between de novo deep vein thrombi and endovenous heat-induced thrombi. J Vasc Surg Venous Lymphat Disord. 2015;3(2):184–9.

Article  PubMed  Google Scholar 

Cheng Z, Jia W, Tian X, Jiang P, Zhang Y, Li J, et al. Cotinine inhibits TLR4/NF-κB signaling pathway and improves deep vein thrombosis in rats. Biosci Rep 2020;40(6)

Harter K, Levine M, Henderson SO. Anticoagulation drug therapy: a review. West J Emerg Med. 2015;16(1):11–7.

Article  PubMed  PubMed Central  Google Scholar 

Bagot CN, Arya R. Virchow and his triad: a question of attribution. Br J Haematol. 2008;143(2):180–90.

Article  PubMed  Google Scholar 

Stark K, Philippi V, Stockhausen S, Busse J, Antonelli A, Miller M, et al. Disulfide HMGB1 derived from platelets coordinates venous thrombosis in mice. Blood. 2016;128(20):2435–49.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Luther N, Shahneh F, Brähler M, Krebs F, Jäckel S, Subramaniam S, et al. Innate Effector-Memory T-Cell Activation Regulates Post-Thrombotic Vein Wall Inflammation and Thrombus Resolution. Circ Res. 2016;119(12):1286–95.

Article  CAS  PubMed  Google Scholar 

Swystun LL, Liaw PC. The role of leukocytes in thrombosis. Blood. 2016;128(6):753–62.

Article  CAS  PubMed  Google Scholar 

Martinod K, Wagner DD. Thrombosis: tangled up in NETs. Blood. 2014;123(18):2768–76.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Budnik I, Brill A. Immune Factors in Deep Vein Thrombosis Initiation. Trends Immunol. 2018;39(8):610–23.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Malaponte G, Signorelli SS, Bevelacqua V, Polesel J, Taborelli M, Guarneri C, et al. Increased Levels of NF-kB-Dependent Markers in Cancer-Associated Deep Venous Thrombosis. PLoS One. 2015;10(7):e0132496.

Article  PubMed  PubMed Central  Google Scholar 

Du T, Tan Z. Relationship between deep venous thrombosis and inflammatory cytokines in postoperative patients with malignant abdominal tumors. Brazilian J Med Biol Res Revista brasileira de pesquisas medicas e biologicas. 2014;47(11):1003–7.

Article  CAS  Google Scholar 

Liu H, Li P, Lin J, Chen W, Guo H, Lin J, et al. Danhong Huayu Koufuye prevents venous thrombosis through antiinflammation via Sirtuin 1/NF-κB signaling pathway. J Ethnopharmacol. 2019;241:111975.

Article  PubMed  Google Scholar 

Zhou H, Li N, Yuan Y, Jin YG, Guo H, Deng W, et al. Activating transcription factor 3 in cardiovascular diseases: a potential therapeutic target. Basic Res Cardiol. 2018;113(5):37.

Article  PubMed  Google Scholar 

Zhang Z, Yin D, Wang Z. Contribution of hypoxia-inducible factor-1α to transcriptional regulation of vascular endothelial growth factor in bovine developing luteal cells. Animal Sci J Nihon chikusan Gakkaiho. 2011;82(2):244–50.

CAS  PubMed  Google Scholar 

Evans CE, Humphries J, Waltham M, Saha P, Mattock K, Patel A, et al. Upregulation of hypoxia-inducible factor 1 alpha in local vein wall is associated with enhanced venous thrombus resolution. Thromb Res. 2011;128(4):346–51.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wang Y, Xu J, Chen J, Fan X, Zhang Y, Yu W, et al. Promoter variants of VTN are associated with vascular disease. Int J Cardiol. 2013;168(1):163–8.

Article  PubMed  Google Scholar 

Wang B, Wang M, Jia S, Li T, Yang M, Ge F. Systematic Survey of the Regulatory Networks of the Long Noncoding RNA BANCR in Cervical Cancer Cells. J Proteome Res. 2022;21(4):1137–52.

Article  CAS  PubMed  Google Scholar 

Kuijpers MJ, de Witt S, Nergiz-Unal R, van Kruchten R, Korporaal SJ, Verhamme P, et al. Supporting roles of platelet thrombospondin-1 and CD36 in thrombus formation on collagen. Arterioscler Thromb Vasc Biol. 2014;34(6):1187–92.

Article  CAS  PubMed  Google Scholar 

Prakash P, Kulkarni PP, Chauhan AK. Thrombospondin 1 requires von Willebrand factor to modulate arterial thrombosis in mice. Blood. 2015;125(2):399–406.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Su Y, Li Q, Zheng Z, Wei X, Hou P. Identification of genes, pathways and transcription factor-miRNA-target gene networks and experimental verification in venous thromboembolism. Sci Rep. 2021;11(1):16352.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gao LN, Li Q, Xie JQ, Yang WX, You CG. Immunological analysis and differential genes screening of venous thromboembolism. Hereditas. 2021;158(1):2.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Pan L, Niu Z, Gao Y, Wang L, Liu Z, Liu J, et al. Silencing of CREB Inhibits HDAC2/TLR4/NF-κB Cascade to Relieve Severe Acute Pancreatitis-Induced Myocardial Injury. Inflammation. 2021;44(4):1565–80.

Article  CAS  PubMed  Google Scholar 

Hu Z, Zhou G. CREB1 Transcriptionally Activates LTBR to Promote the NF-κB Pathway and Apoptosis in Lung Epithelial Cells. Comput Math Methods Med. 2022;2022:9588740.

Article  PubMed  PubMed Central  Google Scholar 

Baik IH, Jo GH, Seo D, Ko MJ, Cho CH, Lee MG, et al. Knockdown of RPL9 expression inhibits colorectal carcinoma growth via the inactivation of Id-1/NF-κB signaling axis. Int J Oncol. 2016;49(5):1953–62.

Article  CAS  PubMed  Google Scholar 

Zhou Z, Zhou H, Zou X, Wang X, Yan M. Formononetin regulates endothelial nitric oxide synthase to protect vascular endothelium in deep vein thrombosis rats. Int J Immunopathol Pharmacol. 2022;36:3946320221111117.

Article  CAS  PubMed  Google Scholar 

Ou M, Zhang Y, Cui S, Zhao S, Tu J. Upregulated MiR-9-5p Protects Against Inflammatory Response in Rats with Deep Vein Thrombosis via Inhibition of NF-κB p50. Inflammation. 2019;42(6):1925–38.

Article  CAS  PubMed  Google Scholar 

Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods (San Diego, Calif). 2001;25(4):402–8.

Article  CAS  PubMed  Google Scholar 

Zhang Z, Hu L, Chen W, Zhou C, Gui G, Lin B. Danhong huayu koufuye prevents deep vein thrombosis through anti-inflammation in rats. J Surg Res. 2016;201(2):340–7.

Article  PubMed  Google Scholar 

Wang Z, Ni S, Zhang H, Fan Y, Xia L, Li N. Silencing SGK1 alleviates osteoarthritis through epigenetic regulation of CREB1 and ABCA1 expression. Life Sci. 2021;268:118733.

Article  CAS  PubMed  Google Scholar 

Liu J, He Q. Ca(2+)/calmodulin-dependent protein kinase IV attenuates inflammation and mitochondrial dysfunction under insulin resistance in C2C12 cells. Arch Physiol Biochem 2020;1–10

Li K, Yang J, Lei XF, Li SL, Yang HL, Xu CQ, et al. EZH2 inhibition promotes ANGPTL4/CREB1 to suppress the progression of ulcerative colitis. Life Sci. 2020;250:117553.

Article  CAS  PubMed  Google Scholar 

Chen J, Ding Q, Jiao X, Wang B, Sun Z, Zhang Y, et al. Dexmedetomidine attenuates hippocampal neuroinflammation in postoperative neurocognitive disorders by inhibiting microRNA-329-3p and activating the CREB1/IL1RA axis. Psychopharmacology. 2022;239(7):2171–86.

Article  CAS  PubMed  Google Scholar 

Bombeli T, Karsan A, Tait JF, Harlan JM. Apoptotic vascular endothelial cells become procoagulant. Blood. 1997;89(7):2429–42.

Article  CAS  PubMed  Google Scholar 

Matsuzaki S, Pouly JL, Canis M. Effects of U0126 and MK2206 on cell growth and re-growth of endometriotic stromal cells grown on substrates of varying stiffness. Sci Rep. 2017;7:42939.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Santulli P, Marcellin L, Chouzenoux S, Boulard V, Just PA, Nicco C, et al. Role of the protein kinase BRAF in the pathogenesis of endometriosis. Expert Opin Ther Targets. 2016;20(8):1017–29.

Article  CAS  PubMed 

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