Effects of perioperative vitamin E and zinc co-supplementation on systemic inflammation and length of stay following coronary artery bypass graft surgery: a randomized controlled trial

Jongman RM, Zijlstra JG, Kok WF, van Harten AE, Mariani MA, Moser J, et al. Off-pump CABG surgery reduces systemic inflammation compared with on-pump surgery but does not change systemic endothelial responses: a prospective randomized study. Shock. 2014;42:121–8. https://doi.org/10.1097/shk.0000000000000190

Article  CAS  PubMed  Google Scholar 

Murphy GJ, Angelini GD. Side effects of cardiopulmonary bypass: what is the reality? J Card Surg. 2004;19:481–8. https://doi.org/10.1111/j.0886-0440.2004.04101.x

Article  CAS  PubMed  Google Scholar 

Milei J, Forcada P, Fraga CG, Grana DR, Iannelli G, Chiariello M, et al. Relationship between oxidative stress, lipid peroxidation, and ultrastructural damage in patients with coronary artery disease undergoing cardioplegic arrest/reperfusion. Cardiovasc Res. 2007;73:710–9. https://doi.org/10.1016/j.cardiores.2006.12.007

Article  CAS  PubMed  Google Scholar 

Christen S, Finckh B, Lykkesfeldt J, Gessler P, Frese-Schaper M, Nielsen P, et al. Oxidative stress precedes peak systemic inflammatory response in pediatric patients undergoing cardiopulmonary bypass operation. Free Radic Biol Med. 2005;38:1323–32. https://doi.org/10.1016/j.freeradbiomed.2005.01.016

Article  CAS  PubMed  Google Scholar 

Pang Y, Li Y, Zhang Y, Wang H, Lang J, Han L, et al. Effects of inflammation and oxidative stress on postoperative delirium in cardiac surgery. Front Cardiovasc Med. 2022;9:1049600. https://doi.org/10.3389/fcvm.2022.1049600

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zakkar M, Guida G, Suleiman MS, Angelini GD. Cardiopulmonary bypass and oxidative stress. Oxid Med Cell Longev. 2015;2015:189863. https://doi.org/10.1155/2015/189863

Article  PubMed  PubMed Central  Google Scholar 

Jouybar R, Kabgani H, Kamalipour H, Shahbazi S, Allahyary E, Rasouli M, et al. The perioperative effect of ascorbic acid on inflammatory response in coronary artery bypass graft surgery; a randomized controlled trial coronary artery bypass graft surgery. Int Cardiovasc Res J. 2017;6:1.

Google Scholar 

Ali- Hasan- Al- Saegh S, Mirhosseini SJ, Tahernejad M, Mahdavi P, Shahidzadeh A, Karimi-Bondarabadi AA, et al. Impact of antioxidant supplementations on cardio-renal protection in cardiac surgery: an updated and comprehensive meta-analysis and systematic review. Cardiovasc Ther. 2016;34:360–70. https://doi.org/10.1111/1755-5922.12207

Article  CAS  PubMed  Google Scholar 

Lassnigg A, Punz A, Barker R, Keznickl P, Manhart N, Roth E, et al. Influence of intravenous vitamin E supplementation in cardiac surgery on oxidative stress: a double-blinded, randomized, controlled study. Br J Anaesth. 2003;90:148–54. https://doi.org/10.1093/bja/aeg042

Article  CAS  PubMed  Google Scholar 

Axford-Gately RA, Wilson GJ. Myocardial infarct size reduction by single high dose or repeated low dose vitamin E supplementation in rabbits. Can J Cardiol. 1993;9:94–8.

CAS  PubMed  Google Scholar 

Jaxa-Chamiec T, Bednarz B, Drozdowska D, Gessek J, Gniot J, Janik K, et al. Antioxidant effects of combined vitamins C and E in acute myocardial infarction. The randomized, double-blind, placebo controlled, multicenter pilot Myocardial Infarction and VITamins (MIVIT) trial. Kardiol Pol. 2005;62:344–50.

PubMed  Google Scholar 

Hou HT, Xue LG, Zhou JY, Wang SF, Yang Q, He GW. Alteration of plasma trace elements magnesium, copper, zinc, iron and calcium during and after coronary artery bypass grafting surgery. J Trace Elem Med Biol. 2020;62:126612 https://doi.org/10.1016/j.jtemb.2020.126612

Article  CAS  PubMed  Google Scholar 

Shenkin A, Berger MM. Micronutrients: a low blood concentration is not equivalent to deficiency. Clin Nutr. 2022;41:2562–4. https://doi.org/10.1016/j.clnu.2022.09.015

Article  PubMed  Google Scholar 

Powell SR. The antioxidant properties of zinc. J Nutr. 2000;130:1447s–54s. https://doi.org/10.1093/jn/130.5.1447S

Article  CAS  PubMed  Google Scholar 

Karagulova G, Yue Y, Moreyra A, Boutjdir M, Korichneva I. Protective role of intracellular zinc in myocardial ischemia/reperfusion is associated with preservation of protein kinase C isoforms. J Pharmacol Exp Ther. 2007;321:517–25.

Article  CAS  PubMed  Google Scholar 

Boehme AK, Hays AN, Kicielinski KP, Arora K, Kapoor N, Lyerly MJ, et al. Systemic inflammatory response syndrome and outcomes in intracerebral hemorrhage. Neurocrit Care. 2016;25:133–40. https://doi.org/10.1007/s12028-016-0255-9

Article  CAS  PubMed  PubMed Central  Google Scholar 

Aguilar Diaz De Leon J, Borges CR. Evaluation of oxidative stress in biological samples using the thiobarbituric acid reactive substances assay. J Vis Exp. 2020. https://doi.org/10.3791/61122

Nouri-Majalan N, Ardakani EF, Forouzannia K, Moshtaghian H. Effects of allopurinol and vitamin E on renal function in patients with cardiac coronary artery bypass grafts. Vasc Health Risk Manag. 2009;5:489.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Duncan A, Talwar D, McMillan DC, Stefanowicz F, O’Reilly DS. Quantitative data on the magnitude of the systemic inflammatory response and its effect on micronutrient status based on plasma measurements. Am J Clin Nutr. 2012;95:64–71. https://doi.org/10.3945/ajcn.111.023812

Article  CAS  PubMed  Google Scholar 

Berger MM, Soguel L, Shenkin A, Revelly JP, Pinget C, Baines M, et al. Influence of early antioxidant supplements on clinical evolution and organ function in critically ill cardiac surgery, major trauma, and subarachnoid hemorrhage patients. Crit Care. 2008;12:R101 https://doi.org/10.1186/cc6981

Article  PubMed  PubMed Central  Google Scholar 

Santos HO, Teixeira FJ, Schoenfeld BJ. Dietary vs. pharmacological doses of zinc: a clinical review. Clin Nutr. 2020;39:1345–53. https://doi.org/10.1016/j.clnu.2019.06.024

Article  CAS  PubMed  Google Scholar 

Ai AL, Hall D, Bolling SF. Interleukin-6 and hospital length of stay after open-heart surgery. Biol Psichiatr Psichofarmakol. 2012;14:79–82.

PubMed  PubMed Central  Google Scholar 

Nouri-Majalan N, Ardakani EF, Forouzannia K, Moshtaghian H. Effects of allopurinol and vitamin E on renal function in patients with cardiac coronary artery bypass grafts. Vasc Health Risk Manag. 2009;5:489–94.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Nathens AB, Neff MJ, Jurkovich GJ, Klotz P, Farver K, Ruzinski JT, et al. Randomized, prospective trial of antioxidant supplementation in critically ill surgical patients. Ann Surg. 2002;236:814.

Article  PubMed  PubMed Central  Google Scholar 

Dey S, Kashav R, Kohli JK, Magoon R, ItiShri, Walian A, et al. Systemic immune-inflammation index predicts poor outcome after elective off-pump CABG: a retrospective, single-center study. J Cardiothorac Vasc Anesth. 2021;35:2397–404. https://doi.org/10.1053/j.jvca.2020.09.092

Article  CAS  PubMed  Google Scholar 

Bastrup-Birk S, Skjoedt MO, Munthe-Fog L, Strom JJ, Ma YJ, Garred P. Pentraxin-3 serum levels are associated with disease severity and mortality in patients with systemic inflammatory response syndrome. PLoS One. 2013;8:e73119 https://doi.org/10.1371/journal.pone.0073119

Article  CAS  PubMed  PubMed Central  Google Scholar 

Holubcova Z, Kunes P, Mandak J, Kolackova M, Andrys C, Krejsek J, et al. Could pentraxin 3 be a new diagnostic marker for excessive inflammatory response in cardiac surgery? Thorac Cardiovasc Surg. 2014;62:670–6. https://doi.org/10.1055/s-0034-1384668

Article  PubMed  Google Scholar 

Gunes T, Bozok S, Kestelli M, Yurekli I, Ilhan G, Ozpak B, et al. α-tocopherol and ascorbic acid in early postoperative period of cardiopulmonary bypass. J Cardiovasc Med (Hagerstown). 2012;13:691–9. https://doi.org/10.2459/JCM.0b013e328356a2dc

Article  CAS  PubMed  Google Scholar 

Mertens K, Lowes D, Webster N, Talib J, Hall L, Davies MJ, et al. Low zinc and selenium concentrations in sepsis are associated with oxidative damage and inflammation. BJA: Br J Anaesth. 2015;114(6):990–9.

Article  CAS  PubMed  Google Scholar 

Schoenborn JR, Wilson CB. Regulation of interferon-gamma during innate and adaptive immune responses. Adv Immunol. 2007;96:41–101. https://doi.org/10.1016/s0065-2776(07)96002-2

Article  CAS  PubMed  Google Scholar 

Franke A, Lante W, Fackeldey V, Becker HP, Thode C, Kuhlmann WD, et al. Proinflammatory and antiinflammatory cytokines after cardiac operation: different cellular sources at different times. Ann Thorac Surg. 2002;74:363–70. https://doi.org/10.1016/s0003-4975(02)03658-5

Article  PubMed  Google Scholar 

Franke A, Lante W, Markewitz A, Weinhold C. In vitro restoration of post-operatively decreased IFN-gamma levels after cardiac surgery and its effect on pro- and anti-inflammatory mediators. J Surg Res. 2006;136:266–72. https://doi.org/10.1016/j.jss.2006.06.036

Article  CAS  PubMed  Google Scholar 

Busch CJ, Binder CJ. Malondialdehyde epitopes as mediators of sterile inflammation. Biochim Biophys Acta Mol Cell Biol Lipids. 2017;1862:398–406. https://doi.org/10.1016/j.bbalip.2016.06.016

Article  CAS  PubMed  Google Scholar 

Canbaz S, Duran E, Ege T, Sunar H, Cikirikcioglu M, Acipayam M. The effects of intracoronary administration of vitamin E on myocardial ischemia-reperfusion injury during coronary artery surgery. Thorac Cardiovasc Surg. 2003;51:57–61. https://doi.org/10.1055/s-2003-38983

Article  CAS  PubMed 

留言 (0)

沒有登入
gif