Adorno G, Lopez E, Burg MA, Loerzel V, Killian M, Dailey AB et al (2018) Positive aspects of having had cancer: a mixed-methods analysis of responses from the American Cancer Society Study of Cancer Survivors-II (SCS-II). Psychooncology 27(5):1412–1425

Article  PubMed  Google Scholar 

Loibl S, Poortmans P, Morrow M, Denkert C, Curigliano G (2021) Epidemiology and risk factors

Ferlay JS, Foucher EL (2013) Cancerinci denceandmortalitypatternsinEurope: estimatesfor40countriesin 2012. EurJCancer 49(6):1374

CAS  Google Scholar 

Sun Y-S, Zhao Z, Yang Z-N, Xu F, Lu H-J, Zhu Z-Y et al (2017) Risk factors and preventions of breast cancer. Int J Biol Sci 13(11):1387

Article  CAS  PubMed  PubMed Central  Google Scholar 

Xia L, Su X, Shen J, Meng Q, Yan J, Zhang C et al (2018) ANLN functions as a key candidate gene in cervical cancer as determined by integrated bioinformatic analysis. Cancer Manag Res 10:663

Article  CAS  PubMed  PubMed Central  Google Scholar 

Vogelstein B, Papadopoulos N, Velculescu VE, Zhou S, Diaz LA Jr, Kinzler KW (2013) Cancer genome landscapes. Science 339(6127):1546–1558

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhang G-M, Goyal H, Song L-L (2018) Bioinformatics analysis of differentially expressed miRNA-related mRNAs and their prognostic value in breast carcinoma Corrigendum in/10.3892/or. 2018.6505. Oncol Rep 39(6):2865–2872

CAS  PubMed  Google Scholar 

Silva TC, Colaprico A, Olsen C, D'Angelo F, Bontempi G, Ceccarelli M, et al (2016) TCGA Workflow: analyze cancer genomics and epigenomics data using Bioconductor packages. F1000Research, 5

Zhang L, Sun S, Wang Y, Mo Y, Xiong F, Zhang S et al (2020) Gossypol induces apoptosis of multiple myeloma cells through the JUN-JNK pathway. Am J Cancer Res 10(3):870

CAS  PubMed  PubMed Central  Google Scholar 

Jiao X, Katiyar S, Willmarth NE, Liu M, Ma X, Flomenberg N et al (2010) c-Jun induces mammary epithelial cellular invasion and breast cancer stem cell expansion. J Biol Chem 285(11):8218–8226

Article  CAS  PubMed  PubMed Central  Google Scholar 

Vleugel MM, Greijer AE, Bos R, van der Wall E, van Diest PJ (2006) c-Jun activation is associated with proliferation and angiogenesis in invasive breast cancer. Hum Pathol 37(6):668–674

Article  CAS  PubMed  Google Scholar 

Liu Y, Chen H, Dong P, Xie G, Zhou Y, Ma Y et al (2020) KIF23 activated Wnt/β-catenin signaling pathway through direct interaction with Amer1 in gastric cancer. Aging (Albany NY) 12(9):8372

Article  CAS  PubMed  Google Scholar 

Sun X, Jin Z, Song X, Wang J, Li Y, Qian X et al (2015) Evaluation of KIF23 variant 1 expression and relevance as a novel prognostic factor in patients with hepatocellular carcinoma. BMC Cancer 15(1):1–9

Article  PubMed  PubMed Central  Google Scholar 

Li Z, Yang H-Y, Zhang X-L, Zhang X, Huang Y-Z, Dai X-Y et al (2022) Kinesin family member 23, regulated by FOXM1, promotes triple negative breast cancer progression via activating Wnt/β-catenin pathway. J Exp Clin Cancer Res 41(1):1–15

Article  Google Scholar 

Krishnan K, Steptoe AL, Martin HC, Pattabiraman DR, Nones K, Waddell N et al (2013) miR-139-5p is a regulator of metastatic pathways in breast cancer. RNA 19(12):1767–1780

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhang H, Yao W, Zhang M, Lu Y, Tang J, Jiang M et al (2021) TTK inhibitor promotes radiosensitivity of liver cancer cells through p21. Biochem Biophys Res Commun 550:84–91

Article  CAS  PubMed  Google Scholar 

Tang J, Lu M, Cui Q, Zhang D, Kong D, Liao X et al (2019) Overexpression of ASPM, CDC20, and TTK confer a poorer prognosis in breast cancer identified by gene co-expression network analysis. Front Oncol 9:310

Article  PubMed  PubMed Central  Google Scholar 

Zhou Q, Ren J, Hou J, Wang G, Ju L, Xiao Y et al (2019) Co-expression network analysis identified candidate biomarkers in association with progression and prognosis of breast cancer. J Cancer Res Clin Oncol 145(9):2383–2396

Article  CAS  PubMed  Google Scholar 

Xie Y, Wang A, Lin J, Wu L, Zhang H, Yang X et al (2017) Mps1/TTK: a novel target and biomarker for cancer. J Drug Target 25(2):112–118

Article  CAS  PubMed  Google Scholar 

Gharehdaghchi Z, Baradaran B, Salehzadeh A, Kazemi T (2020) miR-486-5p regulates cell proliferation and migration in breast cancer. Meta Gene 23:100643

Article  Google Scholar 

Zhu Q, Sun Y, Zhou Q, He Q, Qian H (2018) Identification of key genes and pathways by bioinformatics analysis with TCGA RNA sequencing data in hepatocellular carcinoma. Mol Clin Oncol 9(6):597–606

CAS  PubMed  PubMed Central  Google Scholar 

Huang C, Luo H, Huang Y, Fang C, Zhao L, Li P et al (2021) AURKB, CHEK1 and NEK2 as the potential target proteins of scutellaria barbata on hepatocellular carcinoma: an integrated bioinformatics analysis. Int J Gen Med 14:3295

Article  PubMed  PubMed Central  Google Scholar 

Naorem LD, Muthaiyan M, Venkatesan A (2019) Integrated network analysis and machine learning approach for the identification of key genes of triple-negative breast cancer. J Cell Biochem 120(4):6154–6167

Article  CAS  PubMed  Google Scholar 

Ziegler Y, Guillen VS, Kim SH, Katzenellenbogen JA, Katzenellenbogen BS (2021) Transcription regulation and genome rewiring governing sensitivity and resistance to FOXM1 inhibition in breast cancer. Cancers 13(24):6282

Article  CAS  PubMed  PubMed Central  Google Scholar 

Li S, Liu N, Piao J, Meng F, Li Y (2020) CCNB1 expedites the progression of cervical squamous cell carcinoma via the regulation by FOXM1. Onco Targets Ther 13:12383

Article  CAS  PubMed  PubMed Central  Google Scholar 

Liang WH, Li N, Yuan ZQ, Qian XL, Wang ZH (2019) DSCAM-AS1 promotes tumor growth of breast cancer by reducing miR-204-5p and up-regulating RRM2. Mol Carcinog 58(4):461–473

Article  CAS  PubMed  Google Scholar 

Gao Y, Zhao H, Ren M, Chen Q, Li J, Li Z et al (2020) TOP2A promotes tumorigenesis of high-grade serous ovarian cancer by regulating the TGF-β/Smad pathway. J Cancer 11(14):4181

Article  CAS  PubMed  PubMed Central  Google Scholar 

Qi L, Zhou B, Chen J, Hu W, Bai R, Ye C et al (2019) Significant prognostic values of differentially expressed-aberrantly methylated hub genes in breast cancer. J Cancer 10(26):6618

Article  CAS  PubMed  PubMed Central  Google Scholar 

Fountzilas G, Valavanis C, Kotoula V, Eleftheraki AG, Kalogeras KT, Tzaida O et al (2012) HER2 and TOP2A in high-risk early breast cancer patients treated with adjuvant epirubicin-based dose-dense sequential chemotherapy. J Transl Med 10(1):1–21

Article  Google Scholar 

Liu F, Wu Y, Mi Y, Gu L, Sang M, Geng C (2019) Identification of core genes and potential molecular mechanisms in breast cancer using bioinformatics analysis. Pathol Res Pract 215(7):152436

Article  CAS  PubMed  Google Scholar 

Lu Y, Yang G, Xiao Y, Zhang T, Su F, Chang R et al (2020) Upregulated cyclins may be novel genes for triple-negative breast cancer based on bioinformatic analysis. Breast Cancer 27(5):903–911

Article  PubMed  Google Scholar 

Wei L-M, Li X-Y, Wang Z-M, Wang Y-K, Yao G, Fan J-H et al (2021) Identification of hub genes in triple-negative breast cancer by integrated bioinformatics analysis. Gland Surg 10(2):799

Article  PubMed  PubMed Central  Google Scholar 

Deng J-L, Xu Y-h, Wang G (2019) Identification of potential crucial genes and key pathways in breast cancer using bioinformatic analysis. Front Genet 10:695

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wei S, Zheng Y, Jiang Y, Li X, Geng J, Shen Y et al (2019) The circRNA circPTPRA suppresses epithelial-mesenchymal transitioning and metastasis of NSCLC cells by sponging miR-96-5p. EBioMedicine 44:182–193

Article  PubMed  PubMed Central  Google Scholar 

Gong M-C, Chen W-Q, Jin Z-Q, Lyu J, Meng L-H (2021) Prognostic value and significant pathway exploration associated with TOP2A involved in papillary thyroid cancer. Int J Gen Med 14:3485

Article  PubMed  PubMed Central  Google Scholar 

Wy Q, Sc F, Yq S, Gq J (2020) MiR-96-5p promotes breast cancer migration by activating MEK/ERK signaling. J Gene Med 22(8):e3188

Article  Google Scholar 

Shubbar E, Kovács A, Hajizadeh S, Parris TZ, Nemes S, Gunnarsdóttir K et al (2013) Elevated cyclin B2 expression in invasive breast carcinoma is associated with unfavorable clinical outcome. BMC Cancer 13(1):1–10

Article  CAS  PubMed  PubMed Central  Google Scholar 

Shi H, Zhang L, Qu Y, Hou L, Wang L, Zheng M (2017) Prognostic genes of breast cancer revealed by gene co-expression network analysis. Oncol Lett 14(4):4535–4542

Article  PubMed  PubMed Central