Insulin resistance is a cardiovascular risk factor in hypertensive adults without type 2 diabetes mellitus

James DE, Stöckli J, Birnbaum MJ. The aetiology and molecular landscape of insulin resistance. Nat Rev Mol Cell Biol. 2021;22(11):751–71. Nov.

Article  CAS  PubMed  Google Scholar 

Laakso M, Kuusisto J. Insulin resistance and hyperglycaemia in cardiovascular disease development. Nat Rev Endocrinol. 2014;10(5):293–302. May.

Article  CAS  PubMed  Google Scholar 

Fonseca VA. Defining and characterizing the progression of type 2 diabetes. Diabetes care. 2009 Nov;32 Suppl 2:S151–6.

Weyer C, Tataranni PA, Bogardus C, Pratley RE. Insulin Resistance and Insulin Secretory Dysfunction Are Independent Predictors of Worsening of Glucose Tolerance During Each Stage of Type 2 Diabetes Development. Diabetes Care. 2001;24(1):89–94.

Article  CAS  PubMed  Google Scholar 

UKPDS. U.K. Prospective Diabetes Study 16: Overview of 6 Years’ Therapy of Type II Diabetes: A Progressive Disease. Diabetes. 1995;44(11):1249–58.

Article  Google Scholar 

Li M, Chi X, Wang Y, Setrerrahmane S, Xie W, Xu H. Trends in insulin resistance: insights into mechanisms and therapeutic strategy. Sig Transduct Target Ther. 2022;6;7(1):1–25. Jul.

Article  Google Scholar 

King GL, Park K, Li Q. Selective Insulin Resistance and the Development of Cardiovascular Diseases in Diabetes: The 2015 Edwin Bierman Award Lecture. Diabetes. 2016;65(6):1462–71. Jun.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ormazabal V, Nair S, Elfeky O, Aguayo C, Salomon C, Zuñiga FA. Association between insulin resistance and the development of cardiovascular disease. Cardiovasc Diabetol. 2018;31;17(1):122. Aug.

Article  Google Scholar 

Reaven G. Insulin resistance and coronary heart disease in nondiabetic individuals. Arterioscler Thromb Vasc Biol. 2012;32(8):1754–9. Aug.

Article  CAS  PubMed  Google Scholar 

Zethelius B, Lithell H, Hales CN, Berne C. Insulin sensitivity, proinsulin and insulin as predictors of coronary heart disease. A population-based 10-year, follow-up study in 70-year old men using the euglycaemic insulin clamp. Diabetologia. 2005;48(5):862–7. May.

Article  CAS  PubMed  Google Scholar 

Wang T, Li M, Zeng T, Hu R, Xu Y, Xu M, et al. Association Between Insulin Resistance and Cardiovascular Disease Risk Varies According to Glucose Tolerance Status: A Nationwide Prospective Cohort Study. Diabetes Care. 2022;45(8):1863–72. Aug.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ellulu MS, Patimah I, Khaza’ai H, Rahmat A, Abed Y. Obesity and inflammation: the linking mechanism and the complications. Arch Med Sci. 2017;13(4):851–63. Jun.

Article  CAS  PubMed  Google Scholar 

Scarpellini E, Tack J. Obesity and Metabolic Syndrome: An Inflammatory. Cond Ddi. 2012;30(2):148–53.

CAS  Google Scholar 

Garcia-Carretero R, Vigil-Medina L, Barquero-Perez O. The Use of Machine Learning Techniques to Determine the Predictive Value of Inflammatory Biomarkers in the Development of Type 2 Diabetes Mellitus. Metabolic Syndrome and Related Disorders [Internet]. 2021 Feb 16; Available from: https://doi.org/10.1089/met.2020.0139

Sarwar N, Aspelund T, Eiriksdottir G, Gobin R, Seshasai SRK, Forouhi NG, et al. Markers of dysglycaemia and risk of coronary heart disease in people without diabetes: Reykjavik prospective study and systematic review. Plos Med. 2010;7(5):e1000278. May.

Article  PubMed  PubMed Central  Google Scholar 

Kahn SE, Hull RL, Utzschneider KM. Mechanisms linking obesity to insulin resistance and type 2 diabetes. Nature. 2006;14;444(7121):840–6. Dec.

Article  Google Scholar 

Levey AS, Stevens LA, Schmid CH, Zhang YL, Castro AF, Feldman HI, et al. A new equation to estimate glomerular filtration rate. Ann Intern Med. 2009;150(9):604–12.

Article  PubMed  PubMed Central  Google Scholar 

Unger T, Borghi C, Charchar F, Khan NA, Poulter NR, Prabhakaran D, et al. 2020 International Society of Hypertension Global Hypertension Practice Guidelines. Hypertension. 2020;75(6):1334–57. Jun.

Article  CAS  PubMed  Google Scholar 

Classification and Diagnosis of Diabetes: Standards of Medical Care in Diabetes—2018. Diabetes Care. 2018 Jan 1;41(Supplement 1):S13 LP–S27.

Executive summary of the third report of the national cholesterol education program (NCEP) expert panel on detection, evaluation and treatment of high blood cholesterol in adults (Adult Treatment Panel III), JAMA. 2001 May 16;285(19):2486–97.

R Core Team. A Language and Environment for Statistical Computing [Internet]. Vienna, Austria. Available from: https://www.r-project.org: R Foundation for Statistical Computing; 2020.

Google Scholar 

Bradburn MJ, Clark TG, Love SB, Altman DG. Survival analysis part II: multivariate data analysis—an introduction to concepts and methods. Br J Cancer. 2003;4;89(3):431–6. Aug.

Article  Google Scholar 

Clark TG, Bradburn MJ, Love SB, Altman DG. Survival analysis part I: basic concepts and first analyses. Br J Cancer. 2003;89(2):232–8. Jul.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Allen M, Poggiali D, Whitaker K, Marshall TR, Kievit RA. Raincloud plots: a multi-platform tool for robust data visualization. Wellcome Open Res. 2019;1;4:63–63. Apr.

Article  Google Scholar 

Lakka HM, Salonen JT, Tuomilehto J, Kaplan GA, Lakka TA. Obesity and weight gain are associated with increased incidence of hyperinsulinemia in non-diabetic men. Horm Metab Res. 2002;34(9):492–8. Sep.

Article  CAS  PubMed  Google Scholar 

Ye J. Mechanisms of insulin resistance in obesity. Front Med. 2013;7(1):14–24. Mar.

Article  PubMed  PubMed Central  Google Scholar 

Ye J. Role of insulin in the pathogenesis of free fatty acid-induced insulin resistance in skeletal muscle. Endocr Metab Immune Disord Drug Targets. 2007;7(1):65–74. Mar.

Article  CAS  PubMed  Google Scholar 

Ye J, McGuinness OP. Inflammation during obesity is not all bad: evidence from animal and human studies. Am J Physiol Endocrinol Metab. 2013;304(5):E466–77. Mar.

Article  CAS  PubMed  Google Scholar 

Lau DCW, Dhillon B, Yan H, Szmitko PE, Adipokines VS. molecular links between obesity and atheroslcerosis. Am J Physiol Heart Circ Physiol. 2005;288(5):H2031–41. May.

Article  CAS  PubMed  Google Scholar 

Cinti S, Mitchell G, Barbatelli G, Murano I, Ceresi E, Faloia E, et al. Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans. J Lipid Res. 2005;46(11):2347–55. Nov.

Article  CAS  PubMed  Google Scholar 

Halberg N, Wernstedt-Asterholm I, Scherer PE. The adipocyte as an endocrine cell. Endocrinology and metabolism clinics of North America. 2008 Sep;37(3):753–68, x–xi.

Grundy SM, Cleeman JI, Daniels SR, Donato KA, Eckel RH, Franklin BA, et al. Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement. Circulation. 2005;112(17):2735–52.

Alberti K, Eckel RH, Grundy SM, Zimmet PZ, Cleeman JI, Donato KA, et al. Harmonizing the Metabolic Syndrome A Joint Interim Statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International A. Circulation. 2009;120(16):1640–5.

Haidara M, Mikhailidis DP, Yassin HZ, Dobutovic B, Smiljanic KT, Soskic S, et al. Evaluation of the possible contribution of antioxidants administration in metabolic syndrome. Curr Pharm Des. 2011;17(33):3699–712. Nov.

Article  CAS  PubMed  Google Scholar 

Gluvic Z, Zaric B, Resanovic I, Obradovic M, Mitrovic A, Radak D, et al. Link between Metabolic Syndrome and Insulin Resistance. Curr Vasc Pharmacol. 2017;15(1):30–9.

Article  CAS  PubMed  Google Scholar 

Stokić E, Kupusinac A, Tomić-Naglić D, Zavišić BK, Mitrović M, Smiljenić D, et al. Obesity and vitamin D deficiency: trends to promote a more proatherogenic cardiometabolic risk profile. Angiology. 2015;66(3):237–43. Mar.

Article  PubMed  Google Scholar 

Emerging Risk Factors Collaboration, Kaptoge S, Di Angelantonio E, Lowe G, Pepys MB, Thompson SG, et al. C‑reactive protein concentration and risk of coronary heart disease, stroke, and mortality: an individual participant meta-analysis. Lancet. 2010;9;375(9709):132–40. Jan.

Google Scholar 

Ridker PM. From C‑Reactive Protein to Interleukin‑6 to Interleukin-1: Moving Upstream To Identify Novel Targets for Atheroprotection. Circ Res. 2016;8;118(1):145–56. Jan.

Article  Google Scholar 

DeFronzo RA. Insulin resistance, lipotoxicity, type 2 diabetes and atherosclerosis: the missing links. The Claude Bernard Lecture 2009. Diabetologia. 2010;53(7):1270–87. Jul.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance and β‑cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia. 1985;1;28(7):412–9. Jul.

Article  Google Scholar 

Stern SE, Williams K, Ferrannini E, DeFronzo RA, Bogardus C, Stern MP. Identification of individuals with insulin resistance using routine clinical measurements. Diabetes. 2005;54(2):333–9. Feb.

Article  CAS  PubMed  Google Scholar 

Gayoso-Diz P, Otero-González A, Rodriguez-Alvarez MX, Gude F, García F, De Francisco A, et al. Insulin resistance (HOMA-IR) cut-off values and the metabolic syndrome in a general adult population: effect of gender and age: EPIRCE cross-sectional study. BMC Endocr Disord. 2013;16;13:47. Oct.

Article  Google Scholar 

Lamounier-Zepter V, Ehrhart-Bornstein M, Bornstein SR. Insulin resistance in hypertension and cardiovascular disease. Best Pract Res Clin Endocrinol Metab. 2006;20(3):355–67. Sep.

Article  CAS  PubMed  Google Scholar 

Eddy D, Schlessinger L, Kahn R, Peskin B, Schiebinger R. Relationship of insulin resistance and related metabolic variables to coronary artery disease: a mathematical analysis. Diabetes Care. 2009;32(2):361–6. Feb.

Article  CAS  PubMed  PubMed Central  Google Scholar 

留言 (0)

沒有登入
gif