Dalldorf FG, Willis PW. Angled aorta (“sigmoid septum”) as a cause of hypertrophic subaortic stenosis. Hum Pathol. 1985;16:457–62.

Article  CAS  PubMed  Google Scholar 

Krasnow N. Subaortic septal bulge simulates hypertrophic cardiomyopathy by angulation of the septum with age, independent of focal hypertrophy. An echocardiographic study. J Am Soc Echocardiogr. 1997;10:545–55.

Article  CAS  PubMed  Google Scholar 

Diaz T, Pencina MJ, Benjamin EJ, et al. Prevalence, clinical correlates, and prognosis of discrete upper septal thickening on echocardiography: the Framingham Heart Study. Echocardiography. 2009;26(3):247–53.

Article  PubMed  Google Scholar 

Canepa M, Malti O, David M, et al. Prevalence, clinical correlates, and functional impact of subaortic ventricular septal bulge (from the Baltimore Longitudinal Study of Aging). Am J Cardiol. 2014;114(5):796–802.

Article  PubMed  PubMed Central  Google Scholar 

Funabashi N, Umazume T, Takaoka H, et al. Sigmoid shaped interventricular septum exhibit normal myocardial characteristics and has a relationship with aging, ascending aortic sclerosis and its tilt to left ventricle. Int J Cardiol. 2013;168(4):4484–8.

Article  PubMed  Google Scholar 

Okada K, Mikami T, Kaga S, et al. Decreased aorto-septal angle may contribute to left ventricular diastolic dysfunction in healthy subjects. J Clin Ultrasound. 2014;42(6):341–7.

Article  PubMed  Google Scholar 

Mitchell C, Rahko PS, Blauwet LA, et al. Guidelines for performing a comprehensive transthoracic echocardiographic examination in adults: recommendations from the American Society of Echocardiography. J Am Soc Echocardiogr. 2019;32(1):1–64.

Article  PubMed  Google Scholar 

Tano A, Kasamaki Y, Okumura Y, et al. Major determinants and possible mechanism of dobutamine-induced left ventricular outflow tract obstruction in patients with a sigmoid ventricular septum. J Cardiol. 2013;61(6):428–35.

Article  PubMed  Google Scholar 

Balaban Y, Varım P. Relationship of aortoseptal angle with chronic hypertension, clinical and laboratory data. Int Heart J. 2022;63(6):1099–106.

Article  PubMed  Google Scholar 

Okada K, Kaga S, Tsujita K, et al. Right ventricular basal inflow and outflow tract diameters overestimate right ventricular size in subjects with sigmoid-shaped interventricular septum: a study using three-dimensional echocardiography. Int J Cardiovasc Imaging. 2019;35(7):1211–9.

Article  PubMed  Google Scholar 

Tsuda D, Mori S, Izawa Y, et al. Diversity and determinants of the sigmoid septum and its impact on morphology of the outflow tract as revealed using cardiac computed tomography. Echocardiography. 2022;39(2):248–59.

Article  PubMed  Google Scholar 

Gaudron PD, Liu D, Scholz F, et al. The septal bulge: an early echocardiographic sign in hypertensive heart disease. J Am Soc Hypertens. 2016;10(1):70–80.

Article  PubMed  Google Scholar 

Swinne CJ, Shapiro EP, Jamart J, et al. Age-associated changes in left ventricular outflow tract geometry in normal subjects. Am J Cardiol. 1996;78(9):1070–3.

Article  CAS  PubMed  Google Scholar 

Kobayashi S, Sakai Y, Taguchi I, et al. Causes of increased pressure gradient through the left ventricular outflow tract: a West Coast experience. J Echocardiogr. 2018;16:34–41.

Article  PubMed  Google Scholar 

Ranasinghe I, Yeoh T, Yiannikas J. Negative ionotropic agents for the treatment of left ventricular outflow tract obstruction due to sigmoid septum and concentric left ventricular hypertrophy. Heart Lung Circ. 2011;20(9):579–86.

Article  CAS  PubMed  Google Scholar 

Hirata Y, Yamada H, Kusunose K, et al. Provocation of clinically significant left ventricular outflow tract obstruction by postural change in patients with sigmoid septum. J Echocardiogr. 2018;16(4):173–4.

Article  PubMed  Google Scholar 

Canepa M, Pozios I, Vianello PF, et al. Distinguishing ventricular septal bulge versus hypertrophic cardiomyopathy in the elderly. Heart. 2016;102(14):1087–94.

Article  CAS  PubMed  Google Scholar 

Olafiranye O, Ibrahim M, Kamran H, et al. Narrowed aortoseptal angle is related to increased central blood pressure and aortic pressure wave reflection. Cardiorenal Med. 2012;2(3):177–83.

Article  PubMed  PubMed Central  Google Scholar 

Loncaric F, Nunno L, Mimbrero M, et al. Basal ventricular septal hypertrophy in systemic hypertension. Am J Cardiol. 2020;125(9):1339–46.

Article  PubMed  Google Scholar 

Nakayama T, Oshima Y, Shintani Y, et al. Ventricular sigmoid septum as a risk factor for anthracycline-induced cancer therapeutics-related cardiac dysfunction in patients with malignant lymphoma. Circ Rep. 2022;4(4):173–82.

Article  PubMed  PubMed Central  Google Scholar 

Yalçin F, Yalçin H, Küçükler N, et al. Basal septal hypertrophy as the early imaging biomarker for adaptive phase of remodeling prior to heart failure. J Clin Med. 2021;11(1):75.

Article  PubMed  PubMed Central  Google Scholar 

Dorosz JL, Lezotte DC, Weitzenkamp DA, et al. Performance of 3-dimensional echocardiography in measuring left ventricular volumes and ejection fraction: a systematic review and meta-analysis. J Am Coll Cardiol. 2012;59(20):1799–808.

Article  PubMed  PubMed Central  Google Scholar 

Mor-Avi V, Jenkins C, Kühl HP, et al. Real-time 3-dimensional echocardiographic quantification of left ventricular volumes: multicenter study for validation with magnetic resonance imaging and investigation of sources of error. JACC Cardiovasc Imaging. 2008;1(4):413–23.

Article  PubMed  Google Scholar 

Shibayama K, Watanabe H, Iguchi N, et al. Evaluation of automated measurement of left ventricular volume by novel real-time 3-dimensional echocardiographic system: validation with cardiac magnetic resonance imaging and 2-dimensional echocardiography. J Cardiol. 2013;61(4):281–8.

Article  PubMed  Google Scholar