1   Pulmonary Vascular Disease Unit, Royal Hallamshire Hospital, Sheffield, United Kingdom

2   Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, United Kingdom

,

3   Department of Anaesthesia, Sheffield Teaching Hospitals NHS Trust, Sheffield, United Kingdom

,

Kris Bauchmuller

4   Department of Critical Care, Sheffield Teaching Hospitals NHS Trust, Sheffield, United Kingdom

,

Tessa Bonnett

5   Department of Obstetrics and Gynaecology, Sheffield Teaching Hospitals NHS Trust, Sheffield, United Kingdom

,

Robert Kerry

6   Department of Orthopaedics, Sheffield Teaching Hospitals NHS Trust, Sheffield, United Kingdom

,

Alexa Mannings

3   Department of Anaesthesia, Sheffield Teaching Hospitals NHS Trust, Sheffield, United Kingdom

,

Amanda Nair

3   Department of Anaesthesia, Sheffield Teaching Hospitals NHS Trust, Sheffield, United Kingdom

,

Karen Selby

5   Department of Obstetrics and Gynaecology, Sheffield Teaching Hospitals NHS Trust, Sheffield, United Kingdom

,

Paul P. Skinner

7   Department of Surgery, Sheffield Teaching Hospitals NHS Trust, Sheffield, United Kingdom

,

Victoria J. Wilson

3   Department of Anaesthesia, Sheffield Teaching Hospitals NHS Trust, Sheffield, United Kingdom

,

David G. Kiely

1   Pulmonary Vascular Disease Unit, Royal Hallamshire Hospital, Sheffield, United Kingdom

2   Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, United Kingdom

D.G.K. receives funding from the National Institute for Health and Care Research (NIHR) Sheffield Biomedical Research Centre (BRC). The views expressed are those of the authors and not necessarily those of the NIHR or the Department of Health and Social Care.