A novel phage carrying capsule depolymerase effectively relieves pneumonia caused by multidrug-resistant Klebsiella aerogenes

Alvarez-Marin R, Navarro-Amuedo D, Gasch-Blasi O, et al. A prospective, multicenter case control study of risk factors for acquisition and mortality in Enterobacter species bacteremia. J Infect. 2020;80(2):174–81.

Article  CAS  PubMed  Google Scholar 

De Oliveira D, Forde BM, Kidd TJ, et al. Antimicrobial resistance in ESKAPE pathogens. Clin Microbiol Rev. 2020;33(3):10–128.

Article  Google Scholar 

Freney J, Husson MO, Gavini F, et al. Susceptibilities to antibiotics and antiseptics of new species of the family Enterobacteriaceae. Antimicrob Agents Chemother. 1988;32(6):873–6.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Davin-Regli A, Pages JM. Enterobacter aerogenes and Enterobacter cloacae; versatile bacterial pathogens confronting antibiotic treatment. Front Microbiol. 2015;6:392.

Article  PubMed  PubMed Central  Google Scholar 

Passarelli-Araujo H, Palmeiro JK, Moharana KC, et al. Genomic analysis unveils important aspects of population structure, virulence, and antimicrobial resistance in Klebsiella aerogenes. FEBS J. 2019;286(19):3797–810.

Article  CAS  PubMed  Google Scholar 

Zhang X, Qu F, Jia W, et al. Polymyxin resistance in carbapenem-resistant Enterobacteriaceae isolates from patients without polymyxin exposure: a multicentre study in China. Int J Antimicrob Agents. 2021;57(2): 106262.

Article  CAS  PubMed  Google Scholar 

Da SK, de Almeida DSG, Moura Q, et al. Genetic diversity of virulent polymyxin-resistant Klebsiella aerogenes isolated from intensive care units. Antibiotics (Basel). 2022;11(8):1127.

Article  Google Scholar 

Inglis TJ, Millar MR, Jones JG, et al. Tracheal tube biofilm as a source of bacterial colonization of the lung. J Clin Microbiol. 1989;27(9):2014–8.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Adair CG, Gorman SP, Feron BM, et al. Implications of endotracheal tube biofilm for ventilator-associated pneumonia. Intensive Care Med. 1999;25(10):1072–6.

Article  CAS  PubMed  Google Scholar 

Allen PM, Fisher D, Saunders JR, et al. The role of capsular polysaccharide K21b of Klebsiella and of the structurally related colanic-acid polysaccharide of Escherichia coli in resistance to phagocytosis and serum killing. J Med Microbiol. 1987;24(4):363–70.

Article  CAS  PubMed  Google Scholar 

Williams P, Lambert PA, Haigh CG, et al. The influence of the O and K antigens of Klebsiella aerogenes on surface hydrophobicity and susceptibility to phagocytosis and antimicrobial agents. J Med Microbiol. 1986;21(2):125–32.

Article  CAS  PubMed  Google Scholar 

Pires DP, Costa AR, Pinto G, et al. Current challenges and future opportunities of phage therapy. FEMS Microbiol Rev. 2020;44(6):684–700.

Article  CAS  PubMed  Google Scholar 

Van Nieuwenhuyse B, Van der Linden D, Chatzis O, et al. Bacteriophage-antibiotic combination therapy against extensively drug-resistant Pseudomonas aeruginosa infection to allow liver transplantation in a toddler. Nat Commun. 2022;13(1):5725.

Article  PubMed  PubMed Central  Google Scholar 

Ferry T, Kolenda C, Laurent F, et al. Personalized bacteriophage therapy to treat pandrug-resistant spinal Pseudomonas aeruginosa infection. Nat Commun. 2022;13(1):4239.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Salmond GP, Fineran PC. A century of the phage: past, present and future. Nat Rev Microbiol. 2015;13(12):777–86.

Article  CAS  PubMed  Google Scholar 

Chegini Z, Khoshbayan A, Taati MM, et al. Bacteriophage therapy against Pseudomonas aeruginosa biofilms: a review. Ann Clin Microbiol Antimicrob. 2020;19(1):45.

Article  PubMed  PubMed Central  Google Scholar 

Parasion S, Kwiatek M, Gryko R, et al. Bacteriophages as an alternative strategy for fighting biofilm development. Pol J Microbiol. 2014;63(2):137–45.

Article  PubMed  Google Scholar 

Knecht LE, Veljkovic M, Fieseler L. Diversity and function of phage encoded depolymerases. Front Microbiol. 2019;10:2949.

Article  PubMed  Google Scholar 

Fischetti VA. Exploiting what phage have evolved to control gram-positive pathogens. Bacteriophage. 2011;1(4):188–94.

Article  PubMed  PubMed Central  Google Scholar 

Gan L, Yan C, Cui J, et al. Genetic diversity and pathogenic features in Klebsiella pneumoniae isolates from patients with pyogenic liver abscess and pneumonia. Microbiol Spectr. 2022;10(2): e264621.

Article  Google Scholar 

Gan L, Fu H, Tian Z, et al. Bacteriophage effectively rescues pneumonia caused by prevalent multidrug-resistant Klebsiella pneumoniae in the early stage. Microbiol Spectr. 2022;10(5): e235822.

Article  Google Scholar 

Anand T, Virmani N, Kumar S, et al. Phage therapy for treatment of virulent Klebsiella pneumoniae infection in a mouse model. J Glob Antimicrob Resist. 2020;21:34–41.

Article  PubMed  Google Scholar 

Zhao J, Zhang Z, Tian C, et al. Characterizing the biology of lytic bacteriophage vB_EaeM_phiEap-3 infecting multidrug-resistant Enterobacter aerogenes. Front Microbiol. 2019;10:420.

Article  PubMed  PubMed Central  Google Scholar 

Arndt D, Grant JR, Marcu A, et al. PHASTER: a better, faster version of the PHAST phage search tool. Nucleic Acids Res. 2016;44(W1):W16–21.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Yu G, Lam TT, Zhu H, et al. Two methods for mapping and visualizing associated data on phylogeny using Ggtree. Mol Biol Evol. 2018;35(12):3041–3.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Campos MA, Vargas MA, Regueiro V, et al. Capsule polysaccharide mediates bacterial resistance to antimicrobial peptides. Infect Immun. 2004;72(12):7107–14.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Davin-Regli A, Lavigne JP, Pages JM. Enterobacter spp.: update on taxonomy, clinical aspects, and emerging antimicrobial resistance. Clin Microbiol Rev. 2019;32(4):e00002-19.

Article  PubMed  PubMed Central  Google Scholar 

Marongiu L, Burkard M, Lauer UM, et al. Reassessment of historical clinical trials supports the effectiveness of phage therapy. Clin Microbiol Rev. 2022;35: e6222.

Article  Google Scholar 

Mishra CK, Choi TJ, Kang SC. Isolation and characterization of a bacteriophage F20 virulent to Enterobacter aerogenes. J Gen Virol. 2012;93(Pt 10):2310–4.

Article  CAS  PubMed  Google Scholar 

Li E, Wei X, Ma Y, et al. Isolation and characterization of a bacteriophage phiEap-2 infecting multidrug resistant Enterobacter aerogenes. Sci Rep. 2016;6:28338.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lewis R, Clooney AG, Stockdale SR, et al. Isolation of a novel jumbo bacteriophage effective against Klebsiella aerogenes. Front Med (Lausanne). 2020;7:67.

Article  PubMed  Google Scholar 

Pan YJ, Lin TL, Chen YY, et al. Identification of three podoviruses infecting Klebsiella encoding capsule depolymerases that digest specific capsular types. Microb Biotechnol. 2019;12(3):472–86.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hsieh PF, Lin HH, Lin TL, et al. Two T7-like bacteriophages, K5-2 and K5-4, each encodes two capsule depolymerases: isolation and functional characterization. Sci Rep. 2017;7(1):4624.

Article  PubMed  PubMed Central  Google Scholar 

Pires DP, Oliveira H, Melo LD, et al. Bacteriophage-encoded depolymerases: their diversity and biotechnological applications. Appl Microbiol Biotechnol. 2016;100(5):2141–51.

Article  CAS  PubMed  Google Scholar 

Latka A, Maciejewska B, Majkowska-Skrobek G, et al. Bacteriophage-encoded virion-associated enzymes to overcome the carbohydrate barriers during the infection process. Appl Microbiol Biotechnol. 2017;101(8):3103–19.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ramesh N, Manohar P, Eniyan K, et al. A lysozyme murein hydrolase with broad-spectrum antibacterial activity from Enterobacter phage myPSH1140. Antimicrob Agents Chemother. 2022;66(9): e50622.

Article  Google Scholar 

Hughes KA, Sutherland IW, Clark J, et al. Bacteriophage and associated polysaccharide depolymerases—novel tools for study of bacterial biofilms. J Appl Microbiol. 1998;85(3):583–90.

Article  CAS  PubMed  Google Scholar 

Lin TL, Hsieh PF, Huang YT, et al. Isolation of a bacteriophage and its depolymerase specific for K1 capsule of Klebsiella pneumoniae: implication in typing and treatment. J Infect Dis. 2014;210(11):1734–44.

Article  CAS 

留言 (0)

沒有登入
gif