Genome maintenance meets mechanobiology

Akamatsu Y, Kobayashi T (2015) The human RNA polymerase I transcription terminator complex acts as a replication fork barrier that coordinates the progress of replication with rRNA transcription activity. Mol Cell Biol 35:1871–1881

Article  CAS  PubMed  PubMed Central  Google Scholar 

Al Jord A, Letort G, Chanet S, Tsai FC, Antoniewski C, Eichmuller A, Da Silva C, Huynh JR, Gov NS, Voituriez R et al (2022) Cytoplasmic forces functionally reorganize nuclear condensates in oocytes. Nat Commun 13:5070

Article  PubMed  PubMed Central  Google Scholar 

Alam SG, Zhang Q, Prasad N, Li Y, Chamala S, Kuchibhotla R, Kc B, Aggarwal V, Shrestha S, Jones AL (2016) The mammalian LINC complex regulates genome transcriptional responses to substrate rigidity. Sci Rep 6:1–11

Article  Google Scholar 

Alghoul E, Basbous J, Constantinou A (2021) An optogenetic proximity labeling approach to probe the composition of inducible biomolecular condensates in cultured cells. STAR Protoc 2:100677

Article  CAS  PubMed  PubMed Central  Google Scholar 

Alghoul E, Basbous J, Constantinou A (2023) Compartmentalization of the DNA damage response: mechanisms and functions. DNA Repair 128:103524

Article  CAS  PubMed  Google Scholar 

Almuzzaini B, Sarshad AA, Farrants AK, Percipalle P (2015) Nuclear myosin 1 contributes to a chromatin landscape compatible with RNA polymerase II transcription activation. BMC Biol 13:35

Article  PubMed  PubMed Central  Google Scholar 

Altmeyer M, Lukas J (2013) Guarding against collateral damage during chromatin transactions. Cell 153:1431–1434

Article  CAS  PubMed  Google Scholar 

Amato R, Valenzuela M, Berardinelli F, Salvati E, Maresca C, Leone S, Antoccia A, Sgura A (2020) G-quadruplex stabilization fuels the ALT pathway in ALT-positive osteosarcoma cells. Genes 11:304

Article  CAS  PubMed  PubMed Central  Google Scholar 

Anand RP, Lovett ST, Haber JE (2013) Break-induced DNA replication. Cold Spring Harb Perspect Biol 5:a010397

Article  PubMed  PubMed Central  Google Scholar 

Andreu I, Granero-Moya I, Chahare NR, Clein K, Molina-Jordan M, Beedle AEM, Elosegui-Artola A, Abenza JF, Rossetti L, Trepat X et al (2022) Mechanical force application to the nucleus regulates nucleocytoplasmic transport. Nat Cell Biol 24:896–905

Article  CAS  PubMed  PubMed Central  Google Scholar 

Andrin C, McDonald D, Attwood KM, Rodrigue A, Ghosh S, Mirzayans R, Masson JY, Dellaire G, Hendzel MJ (2012) A requirement for polymerized actin in DNA double-strand break repair. Nucleus 3:384–395

Article  PubMed  Google Scholar 

Arezi B, Kuchta RD (2000) Eukaryotic DNA primase. Trends Biochem Sci 25:572–576

Article  CAS  PubMed  Google Scholar 

Aymard F, Aguirrebengoa M, Guillou E, Javierre BM, Bugler B, Arnould C, Rocher V, Iacovoni JS, Biernacka A, Skrzypczak M et al (2017) Genome-wide mapping of long-range contacts unveils clustering of DNA double-strand breaks at damaged active genes. Nat Struct Mol Biol 24:353–361

Article  CAS  PubMed  PubMed Central  Google Scholar 

Azzalin CM, Reichenbach P, Khoriauli L, Giulotto E, Lingner J (2007) Telomeric repeat–containing RNA and RNA surveillance factors at mammalian chromosome ends. Science 318:798–801

Article  CAS  PubMed  Google Scholar 

Baarlink C, Plessner M, Sherrard A, Morita K, Misu S, Virant D, Kleinschnitz EM, Harniman R, Alibhai D, Baumeister S et al (2017) A transient pool of nuclear F-actin at mitotic exit controls chromatin organization. Nat Cell Biol 19:1389–1399

Article  CAS  PubMed  Google Scholar 

Bai G, Kermi C, Stoy H, Schiltz CJ, Bacal J, Zaino AM, Hadden MK, Eichman BF, Lopes M, Cimprich KA (2020) HLTF promotes fork reversal, limiting replication stress resistance and preventing multiple mechanisms of unrestrained DNA synthesis. Mol Cell 78:1237–1251.e1237

Article  CAS  PubMed  PubMed Central  Google Scholar 

Barbieri M, Scialdone A, Piccolo A, Chiariello AM, di Lanno C, Prisco A, Pombo A, Nicodemi M (2013) Polymer models of chromatin organization. Front Genet 4:113

Article  PubMed  PubMed Central  Google Scholar 

Barnum KJ, O’Connell MJ (2014) Cell cycle regulation by checkpoints. In: Noguchi E, Gadaleta MC (eds) Cell cycle control: mechanisms and protocols. New York, NY, Springer New York, pp 29–40

Chapter  Google Scholar 

Barra V, Fachinetti D (2018) The dark side of centromeres: types, causes and consequences of structural abnormalities implicating centromeric DNA. Nat Commun 9:4340

Article  CAS  PubMed  PubMed Central  Google Scholar 

Barroso-González J, García-Expósito L, Hoang SM, Lynskey ML, Roncaioli JL, Ghosh A, Wallace CT, Modesti M, Bernstein KA, Sarkar SN et al (2019) RAD51AP1 is an essential mediator of alternative lengthening of telomeres. Mol Cell 76:217

Article  PubMed  PubMed Central  Google Scholar 

Barthel FP, Wei W, Tang M, Martinez-Ledesma E, Hu X, Amin SB, Akdemir KC, Seth S, Song X, Wang Q et al (2017) Systematic analysis of telomere length and somatic alterations in 31 cancer types. Nat Genet 49:349–357

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bass TE, Luzwick JW, Kavanaugh G, Carroll C, Dungrawala H, Glick GG, Feldkamp MD, Putney R, Chazin WJ, Cortez D (2016) ETAA1 acts at stalled replication forks to maintain genome integrity. Nat Cell Biol 18:1185–1195

Article  CAS  PubMed  PubMed Central  Google Scholar 

Basu S, Greenwood J, Jones AW, Nurse P (2022) Core control principles of the eukaryotic cell cycle. Nature 607:381–386

Article  CAS  PubMed  PubMed Central  Google Scholar 

Belin BJ, Lee T, Mullins RD (2015) DNA damage induces nuclear actin filament assembly by Formin-2 and Spire-1/2 that promotes efficient DNA repair. eLife 4:e07735

Article  PubMed  PubMed Central  Google Scholar 

Berti M, Cortez D, Lopes M (2020) The plasticity of DNA replication forks in response to clinically relevant genotoxic stress. Nat Rev Mol Cell Biol 21:633–651

Article  CAS  PubMed  Google Scholar 

Berti M, Ray Chaudhuri A, Thangavel S, Gomathinayagam S, Kenig S, Vujanovic M, Odreman F, Glatter T, Graziano S, Mendoza-Maldonado R et al (2013) Human RECQ1 promotes restart of replication forks reversed by DNA topoisomerase I inhibition. Nat Struct Mol Biol 20:347–354

Article  CAS  PubMed  PubMed Central  Google Scholar 

Berti M, Teloni F, Mijic S, Ursich S, Fuchs J, Palumbieri MD, Krietsch J, Schmid JA, Garcin EB, Gon S et al (2020) Sequential role of RAD51 paralog complexes in replication fork remodeling and restart. Nat Commun 11:3531

Article  CAS  PubMed  PubMed Central  Google Scholar 

Berti M, Vindigni A (2016) Replication stress: getting back on track. Nat Struct Mol Biol 23:103–109

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bertillot F, Miroshnikova YA, Wickstrom SA (2022) SnapShot: Mechanotransduction in the nucleus. Cell 185(3638-3638):e3631

Google Scholar 

Bétous R, Mason AC, Rambo RP, Bansbach CE, Badu-Nkansah A, Sirbu BM, Eichman BF, Cortez D (2012) SMARCAL1 catalyzes fork regression and Holliday junction migration to maintain genome stability during DNA replication. Genes Dev 26:151–162

Article  PubMed  PubMed Central  Google Scholar 

Bhargava R, Lynskey ML, O’Sullivan RJ (2022) New twists to the ALTernative endings at telomeres. DNA Repair 115:103342

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bhat KP, Cortez D (2018) RPA and RAD51: fork reversal, fork protection, and genome stability. Nat Struct Mol Biol 25:446–453

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bhat KP, Krishnamoorthy A, Dungrawala H, Garcin EB, Modesti M, Cortez D (2018) RADX modulates RAD51 activity to control replication fork protection. Cell Rep 24:538–545

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bianchi J, Rudd SG, Jozwiakowski SK, Bailey LJ, Soura V, Taylor E, Stevanovic I, Green AJ, Stracker TH, Lindsay HD et al (2013) PrimPol bypasses UV photoproducts during eukaryotic chromosomal DNA replication. Mol Cell 52:566–573

Article  CAS  PubMed  PubMed Central  Google Scholar 

Billault-Chaumartin I, Muriel O, Michon L, Martin SG (2022) Condensation of the fusion focus by the intrinsically disordered region of the formin Fus1 is essential for cell-cell fusion. Curr Biol 32(21):4752–4761

Bleichert F (2019) Mechanisms of replication origin licensing: a structural perspective. Curr Opin Struct Biol 59:195–204

Article  CAS  PubMed 

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