Spitaels D, Mamouris P, Vaes B, Smeets M, Luyten F, Hermens R, et al. Epidemiology of knee osteoarthritis in general practice: a registry-based study. BMJ Open. 2020;10:e031734. https://doi.org/10.1136/bmjopen-2019-031734.

Article  Google Scholar 

Jackson J, Iyer R, Mellor J, Wei W. The burden of pain associated with osteoarthritis in the hip or knee from the patient’s perspective: a multinational cross-sectional study. Adv Ther. 2020;37:3985–99. https://doi.org/10.1007/s12325-020-01445-4.

Article  CAS  Google Scholar 

Cross M, Smith E, Hoy D, Nolte S, Ackerman I, Fransen M, et al. The global burden of hip and knee osteoarthritis: estimates from the Global Burden of Disease 2010 study. Ann Rheum Dis. 2014;73:1323–30. https://doi.org/10.1136/annrheumdis-2013-204763.

Article  Google Scholar 

Rishiraj N, Taunton JE, Lloyd-Smith R, Woollard R, Regan W, Clement DB. The potential role of prophylactic/functional knee bracing in preventing knee ligament injury. Sports Med. 2009;39:937–60. https://doi.org/10.2165/11317790-000000000-00000.

Article  Google Scholar 

Dessery Y, Belzile ÉL, Turmel S, Corbeil P. Comparison of three knee braces in the treatment of medial knee osteoarthritis. The Knee. 2014;21:1107–14. https://doi.org/10.1016/j.knee.2014.07.024.

Article  Google Scholar 

France PE, Paulos LE. Knee Bracing. JAAOS - J Am Acad Orthop Surg. 1994;2:281–7.

Article  CAS  Google Scholar 

Johnson F, Leitl S, Waugh W. The distribution of load across the knee. A comparison of static and dynamic measurements. J Bone Joint Surg Br. 1980;62(3):346–9. https://doi.org/10.1302/0301-620X.62B3.7410467.

Article  CAS  Google Scholar 

Schipplein OD, Andriacchi TP. Interaction between active and passive knee stabilizers during level walking. J Orthop Res. 1991;9:113–9. https://doi.org/10.1002/jor.1100090114.

Article  CAS  Google Scholar 

Kerrigan DC, Lelas JL, Goggins J, Merriman GJ, Kaplan RJ, Felson DT. Effectiveness of a lateral-wedge insole on knee varus torque in patients with knee osteoarthritis. Arch Phys Med Rehabil. 2002;83:889–93. https://doi.org/10.1053/apmr.2002.33225.

Article  Google Scholar 

Pollo FE, Otis JC, Backus SI, Warren RF, Wickiewicz TL. Reduction of medial compartment loads with valgus bracing of the osteoarthritic knee. Am J Sports Med. 2002;30:414–21. https://doi.org/10.1177/03635465020300031801.

Article  Google Scholar 

Cudejko T, van der Esch M, van der Leeden M, Roorda LD, Pallari J, Bennell KL, et al. Effect of soft braces on pain and physical function in patients with knee osteoarthritis: systematic review with meta-analyses. Arch Phys Med Rehabil. 2018;99:153–63. https://doi.org/10.1016/j.apmr.2017.04.029.

Article  Google Scholar 

Brouwer R. Unicompartmental osteoarthritis of the knee: diagnosis and treatment of malalignment. 2006.

Richards JD, Sanchez-Ballester J, Jones RK, Darke N, Livingstone BN. A comparison of knee braces during walking for the treatment of osteoarthritis of the medial compartment of the knee. J Bone Joint Surg Br. 2005;87(7):937–9. https://doi.org/10.1302/0301-620X.87B7.16005.

Article  CAS  Google Scholar 

Perlau R, Frank C, Fick G. The effect of elastic bandages on human knee proprioception in the uninjured population. Am J Sports Med. 1995;23:251–5. https://doi.org/10.1177/036354659502300221.

Article  CAS  Google Scholar 

McNair PJ, Stanley SN, Strauss GR. Knee bracing: effects on proprioception. Arch Phys Med Rehabil. 1996;77:287–9. https://doi.org/10.1016/S0003-9993(96)90114-8.

Article  CAS  Google Scholar 

Birmingham TB, Kramer JF, Kirkley A, Inglis JT, Spaulding SJ, Vandervoort AA. Knee bracing for medial compartment osteoarthritis: effects on proprioception and postural control. Rheumatology. 2001;40:285–9. https://doi.org/10.1093/rheumatology/40.3.285.

Article  CAS  Google Scholar 

Grood ES, Suntay WJ, Noyes FR, Butler DL, Miller EH, Malek M. Total motion measurement during knee laxity. Trans 25th Annu Orthop Res Soc. 1979:80.

Kinzel GL, Hall AS, Hillberry BM. Measurement of the total motion between two body segments—I Analytical development. J Biomech. 1972;5:93–105. https://doi.org/10.1016/0021-9290(72)90022-X.

Article  CAS  Google Scholar 

Blacharski PA, Somerset JH, Murray DG. A three-dimensional study of the kinematics of the human knee. J Biomech. 1975;8:375–84. https://doi.org/10.1016/0021-9290(75)90073-1.

Article  CAS  Google Scholar 

Soudan K, Van Audekercke R, Martens M. Methods, difficulties and inaccuracies in the study of human joint kinematics and pathokinematics by the instant axis concept. Example: the knee joint. J Biomech. 1979;12:27–33. https://doi.org/10.1016/0021-9290(79)90006-X.

Article  CAS  Google Scholar 

Lewis JL, Lew WD, Patrnchak CM, Shybut GT. A new concept in orthotics joint design-the Northwestern University knee orthosis system. Orthot Prosthet. 1983;37:15–23.

Budini K, Richards J, Cole T, Levine D, Trede R, George LS, et al. An exploration of the use of inertial measurement units in the assessment of dynamic postural control of the knee and the effect of bracing and taping. Physiother Pract Res. 2018;39:91–8. https://doi.org/10.3233/PPR-180111.

Article  Google Scholar 

Lew WD, Patrnchak CM, Lewis JL, Schmidt J. A comparison of pistoning forces in orthotic knee joints. Orthot Prosthet. 1982;36(2):85–95.

Beaudreuil J, Bendaya S, Faucher M, Coudeyre E, Ribinik P, Revel M, et al. Clinical practice guidelines for rest orthosis, knee sleeves, and unloading knee braces in knee osteoarthritis. Joint Bone Spine. 2009;76:629–36. https://doi.org/10.1016/j.jbspin.2009.02.002.

Article  Google Scholar 

Budarick AR, MacKeil BE, Fitzgerald S, Cowper-Smith CD. Design evaluation of a novel multicompartment unloader knee brace. J Biomech Eng. 2019:142. https://doi.org/10.1115/1.4044818.

Barrett D, Cobb A, Bentley G. Joint proprioception in normal, osteoarthritic and replaced knees. J Bone Joint Surg Br. 1991;73:53–6. https://doi.org/10.1302/0301-620X.73B1.1991775.

Article  CAS  Google Scholar 

Felson DT, Gross KD, Nevitt MC, Yang M, Lane NE, Torner JC, et al. The effects of impaired joint position sense on the development and progression of pain and structural damage in knee osteoarthritis. Arthritis Care Res. 2009;61:1070–6. https://doi.org/10.1002/art.24606.

Article  Google Scholar 

Moyer RF, Birmingham TB, Bryant DM, Giffin JR, Marriott KA, Leitch KM. Biomechanical effects of valgus knee bracing: a systematic review and meta-analysis. Osteoarthr Cartilage. 2015;23:178–88. https://doi.org/10.1016/j.joca.2014.11.018.

Article  CAS  Google Scholar 

Ramsey DK, Russell ME. Unloader braces for medial compartment knee osteoarthritis: implications on mediating progression. Sports Health. 2009;1:416–26. https://doi.org/10.1177/1941738109343157.

Article  Google Scholar 

Wilson B, Rankin H, Barnes CL. Long-term results of an unloader brace in patients with unicompartmental knee osteoarthritis. Orthopedics. 2011;34:e334–7. https://doi.org/10.3928/01477447-20110627-07.

Article  Google Scholar 

Coudeyre E, Nguyen C, Chabaud A, Pereira B, Beaudreuil J, Coudreuse J-M, et al. A decision-making tool to prescribe knee orthoses in daily practice for patients with osteoarthritis. Ann Phys Rehabil Med. 2018;61:92–8. https://doi.org/10.1016/j.rehab.2018.01.001.

Article  Google Scholar 

Hart HF, Crossley KM, Ackland DC, Cowan SM, Collins NJ. Effects of an unloader knee brace on knee-related symptoms and function in people with post-traumatic knee osteoarthritis after anterior cruciate ligament reconstruction. The Knee. 2016;23:85–90. https://doi.org/10.1016/j.knee.2015.05.006.

Article  Google Scholar 

Toriyama M, Deie M, Shimada N, Otani T, Shidahara H, Maejima H, et al. Effects of unloading bracing on knee and hip joints for patients with medial compartment knee osteoarthritis. Clin Biomech. 2011;26:497–503. https://doi.org/10.1016/j.clinbiomech.2011.01.003.

Article  Google Scholar 

Altman R, Asch E, Bloch D, Bole G, Borenstein D, Brandt K, et al. Development of criteria for the classification and reporting of osteoarthritis: classification of osteoarthritis of the knee. Arthritis Rheum. 1986;29:1039–49. https://doi.org/10.1002/art.1780290816.

Article  CAS  Google Scholar 

Cappozzo A, Catani F, Della Croce U, Leardini A. Position and orientation in space of bones during movement: anatomical frame definition and determination. Clin Biomech. 1995;10:171–8. https://doi.org/10.1016/0268-0033(95)91394-T.

Article  CAS  Google Scholar 

Cappozzo A, Della Croce U, Leardini A, Chiari L. Human movement analysis using stereophotogrammetry: part 1: theoretical background. Gait Posture. 2005;21:186–96. https://doi.org/10.1016/j.gaitpost.2004.01.010.

Article  Google Scholar 

Kito N, Shinkoda K, Yamasaki T, Kanemura N, Anan M, Okanishi N, et al. Contribution of knee adduction moment impulse to pain and disability in Japanese women with medial knee osteoarthritis. Clin Biomech. 2010;25:914–9. https://doi.org/10.1016/j.clinbiomech.2010.06.008.

Article  Google Scholar 

Kirkley A, Webster-Bogaert S, Litchfield R, Amendola A, Macdonald S, Mccalden R, et al. The effect of bracing on varus gonarthrosis*. JBJS. 1999;81:539–48.

Article  CAS  Google Scholar 

Lee PY, Winfield TG, Harris SR, Storey E, Chandratreya A. Unloading knee brace is a cost-effective method to bridge and delay surgery in unicompartmental knee arthritis. BMJ Open Sport Exerc Med. 2017;2:e000195. https://doi.org/10.1136/bmjsem-2016-000195.

Article  Google Scholar 

Matsuno H, Kadowaki KM, Tsuji H. Generation II knee bracing for severe medial compartment osteoarthritis of the knee. Arch Phys Med Rehabil. 1997;78:745–9. https://doi.org/10.1016/S0003-9993(97)90083-6.

Article  CAS  Google Scholar 

Duncan RC, Hay EM, Saklatvala J, Croft PR. Prevalence of radiographic osteoarthritis—it all depends on your point of view. Rheumatology. 2006;45:757–60. https://doi.org/10.1093/rheumatology/kei270.

Article  CAS  Google Scholar 

Fantini Pagani CH, Böhle C, Potthast W, Brüggemann G-P. Short-term effects of a dedicated knee orthosis on knee adduction moment, pain, and function in patients with osteoarthritis. Arch Phys Med Rehabil. 2010;91:1936–41. https://doi.org/10.1016/j.apmr.2010.09.003.

Article  Google Scholar 

Hurley ST, Hatfield Murdock GL, Stanish WD, Hubley-Kozey CL. Is there a dose response for valgus unloader brace usage on knee pain, function, and muscle strength? Arch Phys Med Rehabil. 2012;93:496–502. https://doi.org/10.1016/j.apmr.2011.09.002.

Article  Google Scholar 

Kutzner I, Küther S, Heinlein B, Dymke J, Bender A, Halder AM, et al. The effect of valgus braces on medial compartment load of the knee joint – in vivo load measurements in three subjects. J Biomech. 2011;44:1354–60. https://doi.org/10.1016/j.jbiomech.2011.01.014.

Article  Google Scholar 

Dunn WR, Lyman S, Lincoln AE, Amoroso PJ, Wickiewicz T, Marx RG. The effect of anterior cruciate ligament reconstruction on the risk of knee reinjury. Am J Sports Med. 2004;32:1906–14. https://doi.org/10.1177/0363546504265006.

Article  Google Scholar 

Fantini Pagani CH, Potthast W, Brüggemann G-P. The effect of valgus bracing on the knee adduction moment during gait and running in male subjects with varus alignment. Clin Biomech. 2010;25:70–6. https://doi.org/10.1016/j.clinbiomech.2009.08.010.

Article  Google Scholar 

Brand A, Klöpfer-Krämer I, Morgenstern M, Kröger I, Michel B, Thannheimer A, et al. Effects of knee orthosis adjustment on biomechanical performance and clinical outcome in patients with medial knee osteoarthritis. Prosthet Orthot Int. 2017;41:587–94. https://doi.org/10.1177/0309364