Fouli GE, Gnudi L. The future: experimental therapies for renal disease in diabetes. Nephron. 2019;143:3–7.
Article CAS PubMed Google Scholar
Srivastava SP, Hedayat AF, Kanasaki K, Goodwin JE. microRNA crosstalk nfluences epithelial-to-mesenchymal, endothelial-to-mesenchymal, and macrophage-to-mesenchymal transitions in the kidney. Front Pharm. 2019;10:904–17.
Srivastava SP, Koya D, Kanasaki K. MicroRNAs in kidney fibrosis and diabetic nephropathy: roles on EMT and EndMT. Biomed Res Int. 2013;2013:125469.
Article PubMed PubMed Central Google Scholar
Xu Y, Ouyang C, Lyu D, Lin Z, Zheng W, Xiao F, et al. Diabetic nephropathy execrates epithelial-to-mesenchymal transition (EMT) via miR-2467-3p/Twist1 pathway. Biomed Pharmacother. 2020;125:109920.
Article CAS PubMed Google Scholar
Hua W, Dijke PT, Kostidis S, Giera M, Hornsveld M. TGFβ-induced metabolic reprogramming during epithelial-to-mesenchymal transition in câncer. Cell Mol Life Sci. 2020;77:2103–23.
Article CAS PubMed Google Scholar
Pu J, Zhang Y, Zhou J. Effect of Huai Qi Huang on epithelial-mesenchymal transition of renal tubular epithelial cells through miR-200a. Evid Based Complement Altern Med. 2016;2016:8612190.
Caja L, Tan EJ. Epithelium to Mesenchyme Transition. In: Boffetta P, Hainaut P, eds. Encyclopedia of Cancer. 3rd Edition. New York: Tisch Cancer Institute; Grenoble: Institute for Advanced Biosciences. Academic Press of Elsevier; 2019. p. 14–23.
Xiong M, Jiang L, Zhou Y, Qiu W, Fang L, Tan R, et al. The miR-200 family regulates TGF-β1-induced renal tubular epithelial to mesenchymal transition through Smad pathway by targeting ZEB1 and ZEB2 expression. Am J Physiol Ren Physiol. 2012;302:F369–79.
Sene LB, Mesquita FF, Moraes LN, Santos DC, Carvalho R, Gontijo JAR, et al. Involvement of Renal Corpuscle microRNA Expression on Epithelial-to-mesenchymal transition in maternal low protein diet in adult programmed rats. PLoS ONE. 2010;8:e71310.
Guo C, Dong G, Liang X, Dong Z. Epigenetic regulation in AKI and kidney repair: mechanisms and therapeutic implications. Nat Rev Nephrol. 2019;15:220–39.
Article PubMed PubMed Central Google Scholar
Cavallari I, Ciccarese F, Sharova E, Urso L, Raimondi V, Silic-Benussi M, et al. The miR-200 family of microRNAs: fine tuners of epithelial-mesenchymal transition and circulating cancer biomarkers. Cancers (Basel). 2021;13:5874–907.
Article CAS PubMed Google Scholar
Hill L, Browne G, Tulchinsky E. ZEB/miR-200 feedback loop: at the crossroads of signal transduction in cancer. Int J Cancer. 2013;132:745–54.
Article CAS PubMed Google Scholar
Felício JS, Luz RM, Melo FTC, Resende FS, Oliveira AF, Peixoto AS, et al. Vitamin D on early stages of diabetic kidney disease: a cross-sectional study in patients with type 1 diabetes mellitus. Front Endocrinol (Lausanne). 2016;7:149.
Manucha W, Juncos LI. The protective role of vitamin D on the heart and the kidney. Ther Adv Cardiovasc Dis. 2017;11:12–19.
Article CAS PubMed Google Scholar
Thethi TK, Bajwa MA, Ghanim H, Jo C, Weir M, Goldfine AB, et al. Effect of paricalcitol on endothelial function and inflammation in type 2 diabetes and chronic kidney disease. J Diabetes Complications. 2015;29:433–7.
Article PubMed PubMed Central Google Scholar
Hu X, Liu W, Yan Y, Liu H, Huang Q, Xiao Y, et al. Vitamin D protects against diabetic nephropathy: Evidence-based effectiveness and mechanism. Eur J Pharm. 2019;845:91–98.
Joergensen C, Hovind P, Schmedes A, Parving HH, Rossing P. Vitamin D levels, microvascular complications, and mortality in type 1 diabetes. Diabetes Care. 2011;34:1081–5.
Article CAS PubMed PubMed Central Google Scholar
Reeves PG, Nielsen FH, Fahey GC Jr. AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet. J Nutr. 1993;123:1939–51.
Article CAS PubMed Google Scholar
Junod A, Lambert AE, Stauffacher W, Renold AE. Diabetogenic action of streptozotocin: relationship of dose to metabolic response. J Clin Invest. 1969;48:2129–39.
Article CAS PubMed PubMed Central Google Scholar
Veelken R, Hilgers KF, Hartner A, Haas A, Bohmer KP, Sterzel RB. Nitric oxide synthase isoforms and glomerular hyperfiltration in early diabetic nephropathy. J Am Soc Nephrol. 2000;11:71–9.
Article CAS PubMed Google Scholar
Rodrigues AM, Bergamaschi CT, Araújo RC, Mouro MG, Rosa TS, Higa EM. Effects of training and nitric oxide on diabetic nephropathy progression in type I diabetic rats. Exp Biol Med. 2011;236:1180–7.
Culshaw GJ, Costello HM, Binnie D, Stewart KR, Czopek A, Dhaun N, et al. Impaired pressure natriuresis and non‐dipping blood pressure in rats with early type 1 diabetes mellitus. J Physiol. 2019;597:767–80.
Article CAS PubMed Google Scholar
Derakhshanian H, Djazayery A, Javanbakht MH, Eshraghian MR, Mirshafiey A, Zarei M, et al. The effect of vitamin D on cellular pathways of diabetic nephropathy. Rep. Biochem Mol Biol. 2019;7:217–22.
PubMed PubMed Central Google Scholar
Venkat P, Ning R, Zacharek A, Culmone L, Liang L, Landschoot‐Ward J, et al. Treatment with an Angiopoietin‐1 mimetic peptide promotes neurological recovery after stroke in diabetic rats. CNS Neurosci Ther. 2021;27:48–59.
Article CAS PubMed Google Scholar
Volpini RA, Giovanini C, Costa RS, Coimbra TM. Effect of enalapril and losartan on the events that precede diabetic nephropathy in rats. Diabetes Metab Res Rev. 2003;19:43–51.
Laurell CB. Electroimmuno assay. Scand J Clin Lab Investig. 1972;29:21–37.
Souza CS, Oliveira BSS, Viana GN, Correia TML, Bragança AC, Canale D, et al. Preventive effect of exercise training on diabetic kidney disease in ovariectomized rats with type 1 diabetes. Exp Biol Med. 2019;244:758–69.
Almeida LF, Francescato HDC, Antunes-Rodrigues J, de Paula FJA, Giovanni C, Costa RS, et al. Imbalance of pro- and anti-angiogenic factors due to maternal vitamin D deficiency causes renal microvasculature alterations affecting the adult kidney function. Nutrients. 2019;11:1929–44.
Andersen LB, Przybyl L, Haase N, Versen‐Höynck F, Qadri F, Jorgensen JS, et al. Vitamin D depletion aggravates hypertension and target‐organ damage. J Am Heart Assoc. 2015;4:e001417.
Article PubMed PubMed Central Google Scholar
Darraj H, Badedi M, Poore KR, Hummadi A, Khawaji A, Solan Y, et al. Vitamin D deficiency and glycemic control among patients with type 2 diabetes mellitus in Jazan City, Saudi Arabia. Diabetes Metab Syndr Obes. 2019;12:853–62.
Article CAS PubMed PubMed Central Google Scholar
Bragança AC, Canale D, Gonçalves J, Shimizu MHM, Seguro AC, Volpini RA. Vitamin D deficiency aggravates the renal features of moderate chronic kidney disease in 5/6 nephrectomized rats. Front Med. 2018;5:282–97.
Zhang Y, Kong J, Deb DK, Chang A, Li YC. Vitamin D receptor attenuates renal fibrosis by suppressing the renin-angiotensin system. J Am Soc Nephrol. 2010;21:966–73.
Article CAS PubMed PubMed Central Google Scholar
Hu Z, Zhang H, Yi B, Yang S, Liu J, Hu J, et al. VDR activation attenuate cisplatin induced AKI by inhibiting ferroptosis. Cell Death Dis. 2020;11:1–11.
Li A, Yi B, Han H, Shikun Y, Hu Z, Zheng L, et al. Vitamin D-VDR (vitamin D receptor) regulates defective autophagy in renal tubular epithelial cell in streptozotocin-induced diabetic mice via the AMPK pathway. Autophagy. 2022;18:877–90.
Article CAS PubMed Google Scholar
Schiller A, Gadalean F, Schiller O, Timar R, Bob F, Munteanu M, et al. Vitamin D deficiency prognostic marker or mortality risk factor in end stage renal disease patients with diabetes mellitus treated with hemodialysis–a prospective multicenter study. PLoS ONE. 2015;10:e0126586.
Article PubMed PubMed Central Google Scholar
Holick MF, Binkley NC, Bischoff-Ferrari HA, Gordon CM, Hanley DA, Heaney RP, et al. Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab. 2011;96:1911–30.
Article CAS PubMed Google Scholar
Zhou T, Shen L, Li Z, Jia J, Xing H, Wang N, et al. Severe 25-hydroxyvitamin D deficiency may predict poor renal outcomes in patients with biopsy-proven diabetic nephropathy. Front Endocrinol (Lausanne). 2022;13:1–8.
Gonçalves JG, Bragança AC, Canale D, Shimizu MHM, Sanches TR, Moysés RMA, et al. Vitamin D deficiency aggravates chronic kidney disease progression after ischemic acute kidney injury. PLoS ONE. 2014;9:e107228.
Article PubMed PubMed Central Google Scholar
Zhang X, Song Z, Guo Y, Zhou M. The novel role of TRPC6 in vitamin D ameliorating podocyte injury in STZ-induced diabetic rats. Mol Cell Biochem. 2015;399:155–65.
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