Shi Y.Y. · Su L. · Liu Z.Y. · Cao Y.G. · Chen X. · Zhang R.L. · Liu Q.Z. · Yao J.F. · Zhai W.H. · Ma Q.L. · Jiang E.L. · Han M.Z.

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Article / Publication Details Abstract

Introduction: Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is the standard and curative treatment strategy for patients with hematologic malignancies. Recently, decitabine included regimens are investigated by several studies including ours, which may prevent relapse of primary malignant diseases. Methods: This study was to retrospectively evaluate a 7-day decitabine included regimen with reduced dose of idarubicin for patients with hematologic malignancies who underwent allo-HSCT. Results: A total of 84 patients were enrolled, including 24 cases in 7-day and 60 cases in 5-day decitabine groups, respectively. Patients conditioned with 7-day decitabine regimen showed accelerated neutrophil (12.05±1.97 versus 13.86±3.15; u = 9.309, P

S. Karger AG, Basel

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