Chronic obstructive pulmonary disease: Is serum magnesium level a risk factor for its acute exacerbation? Ketan Kshirsagar , Virendra C Patil * Department of medicine, Krishna institute of medical sciences, Karad (Maharashtra)-415110, Email ID- , doctor1.kims@gmail.com Abstract:   (1040 Views) Background: Determination of modifiable risk factors for treatment and prevention of acute chronic obstructive pulmonary disease (COPD) exacerbation is very crucial. Therefore, the present study determined the role of serum magnesium level in acute COPD exacerbation.
Methods: This prospective study involved 100 patients with an exacerbation of COPD. Demographic data were collected for all the patients, and serum magnesium (Mg2+) levels were determined at two different time intervals. These patients were given standard treatment for COPD. All the patients were followed up after one month and later at three-month intervals for one year.
Results: Majority (72%) of the patients had serum Mg2+<1.7 mg/dL and the odds of hypomagnesemia was 6.54 times more during exacerbations than when they had stable COPD during follow-up. Patients with serum Mg2+<1.7 mg/dL had 9.34 times higher risk of an increased number of acute exacerbations. A significant difference (p<0.05) was observed in the mean serum Mg2+ levels and number of COPD exacerbations among patients with hypomagnesemia at different stages of COPD.
Conclusion: Low serum magnesium level during acute exacerbation is correlated with the increased frequency of acute exacerbation in COPD. Keywords: Serum magnesium, Smoking, Pulmonary diseases, Hypomagnesemia, Normomagnesemia Full-Text [PDF 116 kb]   (191 Downloads)     Type of Study: Original Article | Subject: Pulmonology
Received: 2020/05/11 | Accepted: 2020/08/23 | Published: 2021/03/30 Send email to the article author Add your comments about this article Your username or Email:

‎ 10.22088/cjim.12.2.223

   

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Kshirsagar K, Patil V C. Chronic obstructive pulmonary disease: Is serum magnesium level a risk factor for its acute exacerbation?. Caspian J Intern Med. 2021; 12 (2) :223-227
URL: http://caspjim.com/article-1-2313-en.html