Watanabe T, Yamaguchi Y. Cutaneous manifestations associated with immune checkpoint inhibitors. Front Immunol. 2023;14:1071983. https://doi.org/10.3389/fimmu.2023.1071983.
Article CAS PubMed PubMed Central Google Scholar
Eshaq AM, Flanagan TW, Ba Abbad AA, Makarem ZAA, Bokir MS, Alasheq AK, et al. Immune checkpoint Inhibitor-Associated cutaneous adverse events: mechanisms of occurrence. Int J Mol Sci. 2024;26(1). https://doi.org/10.3390/ijms26010088.
Hargadon KM, Johnson CE, Williams CJ. Immune checkpoint Blockade therapy for cancer: an overview of FDA-approved immune checkpoint inhibitors. Int Immunopharmacol. 2018;62:29–39. https://doi.org/10.1016/j.intimp.2018.06.001.
Article CAS PubMed Google Scholar
Arafat Hossain M. A comprehensive review of immune checkpoint inhibitors for cancer treatment. Int Immunopharmacol. 2024;143(Pt 2):113365. https://doi.org/10.1016/j.intimp.2024.113365.
Article CAS PubMed Google Scholar
Rodríguez G, de Montes AL, Spencer LM, Chimeric Antigen Receptor T, Cells. Immunotherapy for the treatment of leukemia, lymphoma, and myeloma. Mol Cancer Ther. 2023;22(11):1261–9. https://doi.org/10.1158/1535-7163.Mct-23-0043.
Maus MV, June CH. Making better chimeric antigen receptors for adoptive T-cell therapy. Clin Cancer Res. 2016;22(8):1875–84. https://doi.org/10.1158/1078-0432.Ccr-15-1433.
Article CAS PubMed PubMed Central Google Scholar
Dai H, Wang Y, Lu X, Han W. Chimeric antigen receptors modified T-Cells for Cancer therapy. J Natl Cancer Inst. 2016;108(7). https://doi.org/10.1093/jnci/djv439.
Ceci C, Lacal PM, Graziani G. Antibody-drug conjugates: resurgent anticancer agents with multi-targeted therapeutic potential. Pharmacol Ther. 2022;236:108106. https://doi.org/10.1016/j.pharmthera.2021.108106.
Article CAS PubMed Google Scholar
Thomas A, Teicher BA, Hassan R. Antibody-drug conjugates for cancer therapy. Lancet Oncol. 2016;17(6):e254–62. https://doi.org/10.1016/s1470-2045(16)30030-4.
Article CAS PubMed PubMed Central Google Scholar
Dumontet C, Reichert JM, Senter PD, Lambert JM, Beck A. Antibody-drug conjugates come of age in oncology. Nat Rev Drug Discov. 2023;22(8):641–61. https://doi.org/10.1038/s41573-023-00709-2.
Article CAS PubMed Google Scholar
Lu W, Zhang H, Guo Q, Gou Z, Yao J. Selected cutaneous adverse events in patients treated with ICI monotherapy and combination therapy: a retrospective pharmacovigilance study and meta-analysis. Front Pharmacol. 2023;14:1076473. https://doi.org/10.3389/fphar.2023.1076473.
Article CAS PubMed PubMed Central Google Scholar
Schneider BJ, Naidoo J, Santomasso BD, Lacchetti C, Adkins S, Anadkat M, et al. Management of immune-Related adverse events in patients treated with immune checkpoint inhibitor therapy: ASCO guideline update. J Clin Oncol. 2021;39(36):4073–126. https://doi.org/10.1200/jco.21.01440.
Article CAS PubMed Google Scholar
Brudno JN, Maus MV, Hinrichs CS. CAR T cells and T-Cell therapies for cancer: A translational. Sci Rev Jama. 2024;332(22):1924–35. https://doi.org/10.1001/jama.2024.19462.
June CH, Sadelain M. Chimeric antigen receptor therapy. N Engl J Med. 2018;379(1):64–73. https://doi.org/10.1056/NEJMra1706169.
Article CAS PubMed PubMed Central Google Scholar
Wee P, Wang Z. Epidermal growth factor receptor cell proliferation signaling pathways. Cancers (Basel). 2017;9(5). https://doi.org/10.3390/cancers9050052.
Chen D, Hong R, Cao Y, Wu Q, Wang Y, Chen J, et al. Combined Wee1 and EGFR Inhibition reveals synergistic antitumor effect in esophageal squamous cell carcinoma. Carcinogenesis. 2023;44(6):451–62. https://doi.org/10.1093/carcin/bgad038.
Article CAS PubMed Google Scholar
Li Y, Fu R, Jiang T, Duan D, Wu Y, Li C, et al. Mechanism of lethal skin toxicities induced by epidermal growth factor receptor inhibitors and related treatment strategies. Front Oncol. 2022;12:804212. https://doi.org/10.3389/fonc.2022.804212.
Article CAS PubMed PubMed Central Google Scholar
Subbiah V, Kreitman RJ, Wainberg ZA, Cho JY, Schellens JHM, Soria JC, et al. Dabrafenib and Trametinib treatment in patients with locally advanced or metastatic BRAF V600-Mutant anaplastic thyroid Cancer. J Clin Oncol. 2018;36(1):7–13. https://doi.org/10.1200/jco.2017.73.6785.
Article CAS PubMed Google Scholar
Flaherty KT, Infante JR, Daud A, Gonzalez R, Kefford RF, Sosman J, et al. Combined BRAF and MEK Inhibition in melanoma with BRAF V600 mutations. N Engl J Med. 2012;367(18):1694–703. https://doi.org/10.1056/NEJMoa1210093.
Article CAS PubMed PubMed Central Google Scholar
Long GV, Flaherty KT, Stroyakovskiy D, Gogas H, Levchenko E, de Braud F, et al. Dabrafenib plus Trametinib versus Dabrafenib monotherapy in patients with metastatic BRAF V600E/K-mutant melanoma: long-term survival and safety analysis of a phase 3 study. Ann Oncol. 2017;28(7):1631–9. https://doi.org/10.1093/annonc/mdx176.
Article CAS PubMed PubMed Central Google Scholar
Planchard D, Smit EF, Groen HJM, Mazieres J, Besse B, Helland Å, et al. Dabrafenib plus Trametinib in patients with previously untreated BRAF(V600E)-mutant metastatic non-small-cell lung cancer: an open-label, phase 2 trial. Lancet Oncol. 2017;18(10):1307–16. https://doi.org/10.1016/s1470-2045(17)30679-4.
Article CAS PubMed Google Scholar
Diamond EL, Subbiah V, Lockhart AC, Blay JY, Puzanov I, Chau I, et al. Vemurafenib for BRAF V600-Mutant Erdheim-Chester Disease and Langerhans cell histiocytosis: analysis of data from the histology-independent, phase 2, open-label VE-BASKET study. JAMA Oncol. 2018;4(3):384–8. https://doi.org/10.1001/jamaoncol.2017.5029.
Diamond EL, Subbiah V, Lockhart AC, Blay JY, Puzanov I, Chau I, et al. Vemurafenib for BRAF V600-Mutant Erdheim-Chester Disease and Langerhans cell histiocytosis: analysis of data from the histology-independent, Phase 2, open-label VE-BASKET study. JAMA Oncol. 2018;4(3):384–8. https://doi.org/10.1001/jamaoncol.2017.5029.
Wen PY, Stein A, van den Bent M, De Greve J, Wick A, de Vos F, et al. Dabrafenib plus Trametinib in patients with BRAF(V600E)-mutant low-grade and high-grade glioma (ROAR): a multicentre, open-label, single-arm, phase 2, basket trial. Lancet Oncol. 2022;23(1):53–64. https://doi.org/10.1016/s1470-2045(21)00578-7.
Article CAS PubMed Google Scholar
Gershenson DM, Miller A, Brady WE, Paul J, Carty K, Rodgers W, et al. Trametinib versus standard of care in patients with recurrent low-grade serous ovarian cancer (GOG 281/LOGS): an international, randomised, open-label, multicentre, phase 2/3 trial. Lancet. 2022;399(10324):541–53. https://doi.org/10.1016/s0140-6736(21)02175-9.
Article CAS PubMed PubMed Central Google Scholar
André F, Ciruelos E, Rubovszky G, Campone M, Loibl S, Rugo HS, et al. Alpelisib for PIK3CA-Mutated, hormone Receptor-Positive advanced breast Cancer. N Engl J Med. 2019;380(20):1929–40. https://doi.org/10.1056/NEJMoa1813904.
Janku F, Yap TA, Meric-Bernstam F. Targeting the PI3K pathway in cancer: are we making headway? Nat Rev Clin Oncol. 2018;15(5):273–91. https://doi.org/10.1038/nrclinonc.2018.28.
Article CAS PubMed Google Scholar
Furman RR, Sharman JP, Coutre SE, Cheson BD, Pagel JM, Hillmen P, et al. Idelalisib and rituximab in relapsed chronic lymphocytic leukemia. N Engl J Med. 2014;370(11):997–1007. https://doi.org/10.1056/NEJMoa1315226.
Article CAS PubMed PubMed Central Google Scholar
Dreyling M, Santoro A, Mollica L, Leppä S, Follows G, Lenz G, et al. Long-term safety and efficacy of the PI3K inhibitor Copanlisib in patients with relapsed or refractory indolent lymphoma: 2-year follow-up of the CHRONOS-1 study. Am J Hematol. 2020;95(4):362–71. https://doi.org/10.1002/ajh.25711.
Article CAS PubMed Google Scholar
Flinn IW, Hillmen P, Montillo M, Nagy Z, Illés Á, Etienne G, et al. The phase 3 DUO trial: Duvelisib vs ofatumumab in relapsed and refractory CLL/SLL. Blood. 2018;132(23):2446–55. https://doi.org/10.1182/blood-2018-05-850461.
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