A case report and a literature review about central nervous system involvement in monomorphic epitheliotropic intestinal T cell lymphoma

Alaggio R, Amador C, Anagnostopoulos I, Attygalle AD, Araujo IBO, Berti E, et al. The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: lymphoid neoplasms. Leukemia. 2022;36(7):1720–1748. https://doi.org/10.1038/s41375-022-01620-2

Campo E, Jaffe ES, Cook JR, Quintanilla-Martinez L, Swerdlow SH, Anderson KC et al (2022) The International Consensus Classification of Mature Lymphoid Neoplasms: a report from the Clinical Advisory Committee. Blood 140(11):1229–1253. https://doi.org/10.1182/blood.2022015851.Erratum.In:Blood.2023;141(4):437.doi:10.1182/blood.2022019016

Chan JK, Chan AC, Cheuk W, Wan SK, Lee WK, Lui YH et al (2011) Type II enteropathy-associated T-cell lymphoma: a distinct aggressive lymphoma with frequent γδ T-cell receptor expression. Am J Surg Pathol 35(10):1557–1569. https://doi.org/10.1097/PAS.0b013e318222dfcd

Article  PubMed  Google Scholar 

Chan TSY, Lee E, Khong PL, Tse EWC, Kwong YL (2018) Positron emission tomography computed tomography features of monomorphic epitheliotropic intestinal T-cell lymphoma. Hematology 23(1):10–16. https://doi.org/10.1080/10245332.2017.1335979

Article  PubMed  Google Scholar 

Tomita S, Kikuti YY, Carreras J, Sakai R, Takata K, Yoshino T et al (2020) Monomorphic epitheliotropic intestinal T-cell lymphoma in Asia frequently shows SETD2 alterations. Cancers (Basel) 12(12):3539. https://doi.org/10.3390/cancers12123539

Article  CAS  PubMed  Google Scholar 

Van Vliet C, Spagnolo DV (2020) T- and NK-cell lymphoproliferative disorders of the gastrointestinal tract: review and update. Pathology 52(1):128–141. https://doi.org/10.1016/j.pathol.2019.10.001

Article  CAS  PubMed  Google Scholar 

Veloza L, Cavalieri D, Missiaglia E, Ledoux-Pilon A, Bisig B, Pereira B et al (2023) Monomorphic epitheliotropic intestinal T-cell lymphoma comprises morphologic and genomic heterogeneity impacting outcome. Haematologica 108(1):181–195. https://doi.org/10.3324/haematol.2022.281226

Article  CAS  PubMed  Google Scholar 

Nato Y, Miyazaki K, Imai H, Nakano E, Kageyama Y, Ino K et al (2021) Early central nervous system relapse of monomorphic epitheliotropic intestinal T-cell lymphoma after cord blood transplantation. Int J Hematol 114(1):129–135. https://doi.org/10.1007/s12185-021-03107-9.Erratum.In:IntJHematol.2022;115(3):452-453.doi:10.1007/s12185-022-03295-y

Nishida H, Endo K, Hatano M, Tatekawa N, Mashima E, Hashida R et al (2015) Isolated central nervous system relapse in type II enteropathy-associated T cell lymphoma. Rinsho Ketsueki 56(6):692–698. https://doi.org/10.11406/rinketsu.56.692

Article  PubMed  Google Scholar 

Yi JH, Lee GW, Do YR, Jung HR, Hong JY, Yoon DH et al (2019) Multicenter retrospective analysis of the clinicopathologic features of monomorphic epitheliotropic intestinal T-cell lymphoma. Ann Hematol 98(11):2541–2550. https://doi.org/10.1007/s00277-019-03791-y

Article  PubMed  Google Scholar 

Morimoto A, Fujioka Y, Ushiku T, Kurokawa M (2021) Monomorphic epitheliotropic intestinal T-cell lymphoma invades brain. Intern Med 60(5):815–816. https://doi.org/10.2169/internalmedicine.5925-20

Article  PubMed  Google Scholar 

Chuah YY, Tashi T, Lee YY, Fu TY, Shih CA (2020) Enteropathy-associated T-cell Lymphoma (EATL) with intracranial metastasis: a rare and dismal condition. Acta Gastroenterol Belg 83(1):77–80

CAS  PubMed  Google Scholar 

Kubota Y, Kusaba K (2018) Monomorphic epitheliotropic intestinal T-cell lymphoma involving the central nervous system. Blood 131(15):1765. https://doi.org/10.1182/blood-2017-11-819136

Article  CAS  PubMed  Google Scholar 

Suzuki Y, Minemura H, Tomita H, Saito M, Watanabe N, Umeda T et al (2020) Monomorphic epitheliotropic intestinal T-cell lymphoma involving the lung and brain: a rare case study. Intern Med 59(20):2559–2563. https://doi.org/10.2169/internalmedicine.4710-20

Article  PubMed  PubMed Central  Google Scholar 

Yip PL, Lam CP, Lau WP, Luk TH, Lau SJ (2021) Temozolomide showed rapid activity in a patient with refractory CNS monomorphic epitheliotropic T cell lymphoma. Ann Hematol 100(12):3049–3050. https://doi.org/10.1007/s00277-020-04282-1

Article  PubMed  Google Scholar 

Liu TZ, Zheng YJ, Zhang ZW, Li SS, Chen JT, Peng AH et al (2020) Chidamide based combination regimen for treatment of monomorphic epitheliotropic intestinal T cell lymphoma following radical operation: Two case reports. World J Clin Cases 8(7):1278–1286. https://doi.org/10.12998/wjcc.v8.i7.1278

Article  PubMed  PubMed Central  Google Scholar 

Talabong DJA, Laguerre E, Chen NN, Zeng J (2023) Monomorphic epitheliotropic intestinal T-cell lymphoma involving the central nervous system: a rare case report with comprehensive autopsy neuropathological examinations. J Hematop 16(3):155–160. https://doi.org/10.1007/s12308-023-00557-4

Article  PubMed  Google Scholar 

Ding X, Zhang M, Zhan Q, Zhang H, Zhang R, Yan X et al (2024) Monomorphic epitheliotropic intestinal T-cell lymphoma: report of four cases and literature review. J Int Med Res 52(8):3000605241271756. https://doi.org/10.1177/03000605241271756

Article  CAS  PubMed  Google Scholar 

Marchi E, Craig JW, Kalac M. Current and upcoming treatment approaches to uncommon subtypes of PTCL (EATL/MEITL, SPTCL, HSTCL). Blood. 2024; 24:blood.2023021788. https://doi.org/10.1182/blood.2023021788

Wilson MR, Eyre TA, Kirkwood AA, Wong Doo N, Soussain C, Choquet S et al (2022) Timing of high-dose methotrexate CNS prophylaxis in DLBCL: a multicenter international analysis of 1384 patients. Blood 139(16):2499–2511. https://doi.org/10.1182/blood.2021014506

Article  CAS  PubMed  Google Scholar 

Ellin F, Landström J, Jerkeman M, Relander T (2015) Central nervous system relapse in peripheral T-cell lymphomas: a Swedish Lymphoma Registry study. Blood 126(1):36–41. https://doi.org/10.1182/blood-2014-12-616961

Article  CAS  PubMed  Google Scholar 

Gurion R, Mehta N, Migliacci JC, Zelenetz A, Moskowitz A, Lunning M et al (2016) Central nervous system involvement in T-cell lymphoma: a single center experience. Acta Oncol 55(5):561–566. https://doi.org/10.3109/0284186X.2015.1118656

Article  CAS  PubMed  Google Scholar 

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