Ross R (1999) Atherosclerosis — an inflammatory disease. N Engl J Med 77:302–309

Google Scholar 

Arbustini E, Morbini P, Dal Bello B et al (1999) From plaque biology to clinical setting. Am Heart J 138 (2), S55–S60

Gensini GG (1983) A more meaningful scoring system for determining the severity of coronary heart disease. Am J Cardiol 51:606

Article  CAS  PubMed  Google Scholar 

Sinning C, Lillpopp L, Appelbaum S et al (2013) Angiographic score assessment improves cardiovascular risk prediction: the clinical value of SYNTAX and Gensini application. Springer 102:495–503

CAS  Google Scholar 

Wang KY, Zheng YT, Wu TT, Ma YT, Xie X (2022) Predictive value of Gensini score in the long-term outcomes of patients with coronary artery Disease who underwent PCI. Front Cardiovasc Med 8:778615

Article  PubMed  PubMed Central  Google Scholar 

Prati F, Regar E, Mintz et al (2010) Expert review document on methodology, terminology, and clinical applications of optical coherence tomography: physical principles, methodology of image acquisition, and clinical application for assessment of coronary arteries and atherosclerosis. Eur Heart J 31:401–415

Article  PubMed  Google Scholar 

Jang IK, Tearney GJ, MacNeill B et al (2005) In vivo characterization of coronary atherosclerotic plaque by use of optical coherence tomography. Circulation 111:1551–1555

Article  PubMed  PubMed Central  Google Scholar 

Prati F, Romagnoli E, Gatto L et al (2020) Relationship between coronary plaque morphology of the left anterior descending artery and 12 months clinical outcome: the CLIMA study. Eur. Heart J 41:383–391

Article  Google Scholar 

Kubo T, Ino Y, Mintz GS et al (2021) Optical coherence tomography detection of vulnerable plaques at high risk of developing acute coronary syndrome. Eur Heart J Cardiovasc Imaging 22:1376–1384

Google Scholar 

Kedhi E, Berta B, Roleder T et al (2021) Thin-cap fibroatheroma predicts clinical events in diabetic patients with normal fractional flow reserve: the COMBINE OCT-FFR trial. Eur Heart J 42:4671–4679

Article  CAS  PubMed  Google Scholar 

Tearney GJ, Regar E, Akasaka T et al (2012) Consensus standards for acquisition, measurement, and reporting of intravascular optical coherence tomography studies: a report from the International Working Group for Intravascular Optical Coherence Tomography standardization and validation. J Am Coll Cardiol 59:1058–1072

Article  PubMed  Google Scholar 

Cutlip DE, Windecker S, Mehran R et al (2007) Clinical end points in coronary stent trials: a case for standardized definitions. Circulation 115:2344–2351

Article  PubMed  Google Scholar 

Park SJ, Ahn JM, Kang DY (2024) Preventive percutaneous coronary intervention versus optimal medical therapy alone for the treatment of vulnerable atherosclerotic coronary plaques (PREVENT): a multicentre, open-label, randomised controlled trial. Lancet 403(10438):1753–1765

Article  CAS  PubMed  Google Scholar 

Biccirè FG, Budassi S, Ozaki Y et al (2023) Optical coherence tomography-derived lipid core burden index and clinical outcomes: results from the CLIMA registry. Eur Heart J Cardiovasc Imaging 24(4):437–445

Article  PubMed  Google Scholar 

Serruys PW, Morice M-C, Kappetein et al (2009) Percutaneous coronary intervention versus coronary-artery bypass grafting for severe coronary artery disease. N Engl J Med 360:961–972

Article  CAS  PubMed  Google Scholar 

Stephan T, Thoma E, Rattka M et al (2021) Impact of extent of coronary artery disease and percutaneous revascularization assessed by the SYNTAX score on outcomes following transcatheter aortic valve replacement. BMC Cardiovasc Disord 21:568

Article  CAS  PubMed  PubMed Central  Google Scholar 

Yokokawa T, Yoshihisa A, Kiko T et al (2020) Residual Gensini score is Associated with Long-Term Cardiac Mortality in patients with heart failure after percutaneous coronary intervention. Circ Rep 2:89–94

Article  PubMed  PubMed Central  Google Scholar 

Avci A, Fidan S, Tabakci MM et al (2016) Association between the Gensini score and carotid artery stenosis. Korean Circ J 46:639–645

Article  PubMed  PubMed Central  Google Scholar 

Motoyama S, Ito H, Sarai M et al (2015) Plaque characterization by Coronary computed Tomography Angiography and the likelihood of Acute coronary events in Mid-term Follow-Up. J Am Coll Cardiol 66:337–346

Article  PubMed  Google Scholar 

Lee JM, Choi KH, Koo BK et al (2019) Prognostic Implications of Plaque Characteristics and Stenosis Severity in Patients With Coronary Artery Disease. J Am Coll Cardiol. PMID: 31097161

Puchner SB, Liu T, Mayrhofer T et al (2014) High-risk plaque detected on coronary CT angiography predicts acute coronary syndromes independent of significant stenosis in acute chest pain: results from the ROMICAT-II trial. J Am Coll Cardiol 64:684–692

Article  PubMed  PubMed Central  Google Scholar 

Cheng JM, Garcia-Garcia HM, de Boer SP et al (2014) In vivo detection of high-risk coronary plaques by radiofrequency intravascular ultrasound and cardiovascular outcome: results of the ATHEROREMO-IVUS study. Eur Heart J 35(10):639–647

Article  PubMed  Google Scholar 

Chang HJ, Lin FY, Lee SE et al (2018) Coronary atherosclerotic precursors of Acute Coronary syndromes. J Am Coll Cardiol 22:2511–2522

Article  Google Scholar 

Lee SE, Sung JM, Rizvi A et al (2018) Quantification of coronary atherosclerosis in the Assessment of Coronary Artery Disease. Circ Cardiovasc Imaging 11:e007562. https://doi.org/10.1161/CIRCIMAGING.117.007562

Article  PubMed  Google Scholar 

Biccirè FG, Gatto L, La Porta Y et al (2023) Effects of lipid lowering therapies on vulnerable plaque features: an updated narrative review of the literature. J Cardiovasc Dev Dis 10(6):260

PubMed  PubMed Central  Google Scholar 

Nicholls SJ, Kataoka Y, Nissen SE et al (2022) Effect of Evolocumab on Coronary Plaque phenotype and burden in statin-treated patients following myocardial infarction. JACC Cardiovasc Imaging 15(7):1308–1321

Article  PubMed  Google Scholar 

Biccirè FG, Häner J, Losdat S et al (2023) Concomitant coronary atheroma regression and stabilization in response to lipid-lowering therapy. J Am Coll Cardiol 82(18):1737–1747

Article  PubMed  Google Scholar