Abdel-Ghaffar MM, Saad A-GE, Moharm IM, Sharaf OF, Badr MT, Ibrahim AF (2017) Parasitological and histopathological effects of some antischistosome drugs in Schistosoma mansoni- infected mice. Menoufia Med J 30(4):1193

Article  Google Scholar 

Arafa NMS, Salem SM, Farid OAHA (2010) Influence of Echinacea extract pre-or postnatal supplementation on immune and oxidative status of growing rabbits. Ital J Anim Sci 3389. https://doi.org/10.4081/ijas.2010.e63

Aragão WAB, Teixeira FB, Fagundes NCF, Fernandes RM, Fernandes LMP, Da Silva MCF, Amado LL, Sagica FES, Oliveira EHC, Crespo-Lopez ME, Maia CSF, Lima RR (2018) Hippocampal dysfunction provoked by mercury chloride exposure: Evaluation of cognitive impairment, oxidative stress, tissue injury and nature of cell death. Oxidative Medicine and Cellular Longevity, 2018 https://doi.org/10.1155/2018/7878050

Aujla SJ, Chan YR, Zheng M, Fei M, Askew DJ, Pociask DA, Reinhart TA, McAllister F, Edeal J, Gaus K, Husain S, Kreindler JL, Dubin PJ, Pilewski JM, Myerburg MM, Mason CA, Iwakura Y, Kolls JK (2008) IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia. Nat Med 14(3):275–281. https://doi.org/10.1038/nm1710

Article  CAS  PubMed  PubMed Central  Google Scholar 

Baj A, Moro E, Bistoletti M, Orlandi V, Crema F, Giaroni C (2019) Glutamatergic signaling along the Microbiota-Gut-Brain Axis. Int J Mol Sci 2019 20(6):1482. https://doi.org/10.3390/IJMS20061482

Article  CAS  Google Scholar 

Bąska P, Norbury LJ (2022) The role of nuclear factor Kappa B (NF-κB) in the Immune response against parasites. Pathogens 11(3):1–24. https://doi.org/10.3390/pathogens11030310

Article  CAS  Google Scholar 

Bercik P, Verdu EF, Foster JA, MacRi J, Potter M, Huang X, Malinowski P, Jackson W, Blennerhassett P, Neufeld KA, Lu J, Khan WI, Corthesytheulaz I, Cherbut C, Bergonzelli GE, Collins SM (2010) Chronic gastrointestinal inflammation induces anxiety-like behavior and alters central nervous system biochemistry in mice. Gastroenterology 139(6):2102–2112. https://doi.org/10.1053/j.gastro.2010.06.063

Article  CAS  PubMed  Google Scholar 

Castañeda TR, Marquez De Prado B, Prieto D, Mora F (2004) Circadian rhythms of dopamine, glutamate, and GABA in the striatum and nucleus accumbens of the awake rat: modulation by light. J Pineal Res 36(3):177185. https://doi.org/10.1046/j.1600079X.2003.00114.x

Article  Google Scholar 

Cermakian N, Lange T, Golombek D, Sarkar D, Nakao A, Shibata S, Mazzoccoli G (2013) Crosstalk between the circadian clock circuitry and the immune system. Chronobiol Int 30(7):870–888. https://doi.org/10.3109/07420528.2013.782315

Article  CAS  PubMed  PubMed Central  Google Scholar 

Colley DG, Secor WE (2014) Immunology of human schistosomiasis. Parasite immunology, vol 36. Blackwell Publishing Ltd, pp 347–357. https://doi.org/10.1111/pim.12087

Cornell W (2019) Schistosomiasis: Still a Cause of Significant Morbidity and Mortality Mohamud A Verjee. https://doi.org/10.2147/RRTM.S204345

Cryan JF, Dinan TG (2012) Mind-altering microorganisms: the impact of the gut microbiota on brain and behavior. Nat Rev Neurosci 13(10):701–712. https://doi.org/10.1038/nrn3346

Article  CAS  PubMed  Google Scholar 

Feng D, Wang Y, Wang H, Weng H, Kong X, Martin-Murphy BV, Li Y, Park O, Dooley S, Ju C, Gao B (2014) Acute and Chronic effects of IL-22 on Acetaminophen-Induced Liver Injury. J Immunol 193(5):2512–2518. https://doi.org/10.4049/jimmunol.1400588

Article  CAS  PubMed  Google Scholar 

Ferrari TCA, Gazzinelli G, Corrêa-Oliveira R (2008) Immune response and pathogenesis of neuro schistosomiasis mansoni. Acta Trop 108(2–3):83–88. https://doi.org/10.1016/j.actatropica.2008.02.010

Article  CAS  PubMed  Google Scholar 

Fricke WF, Song Y, Wang AJ, Smith A, Grinchuk V, Mongodin E, Pei C, Ma B, Lu N, Urban JF, Shea-Donohue T, Zhao A (2015) Type 2 immunity-dependent reduction of segmented filamentous bacteria in mice infected with the helminthic parasite Nippostrongylus brasiliensis. Microbiome 3(1):40. https://doi.org/10.1186/S40168-015-0103-8/FIGURES/7

Article  PubMed  PubMed Central  Google Scholar 

Furuse M (2021) Aging modifies the concentration and metabolism of amino acids and associated receptor functionality in the brain. Factors Affecting Neurol Aging: Genet Neurol Behav Diet 97–108. https://doi.org/10.1016/B978-0-12-817990-1.00009-3

Gao B, Xiang X (2018) Interleukin-22 from bench to bedside: a promising drug for epithelial repair. Cell Mol Immunol 2018 16(7):7. https://doi.org/10.1038/s41423-018-0055-6

Article  CAS  Google Scholar 

Giacomin PR, Kraeuter AK, Albornoz EA, Jin S, Bengtsson M, Gordon R, Woodruff TM, Urich T, Sarnyai Z, Magalhães RJS (2018) Chronic helminth infection perturbs the gut-brain axis, promotes neuropathology, and alters behavior. J Infect Dis 218(9). https://doi.org/10.1093/infdis/jiy092

Ismail AS, Behrendt CL (2009) Hooper LV reciprocal interactions between commensal bacteria and gamma delta intraepithelial lymphocytes during mucosal injury. J Immunol 182:3047–3054

Article  CAS  PubMed  Google Scholar 

Jatsa HB, Kenfack CM, Simo DN, Feussom NG, Nkondo ET, Tchuem Tchuente LA, Tsague CD, Dongo E, Kamtchouing P (2015) Schistosomicidal, hepatoprotective and antioxidant activities of the methanolic fraction from Clerodendrum umbellatum Poir leaves aqueous extract in Schistosoma mansoni infection in mice. BMC Complement Altern Med 15(1):1–9. https://doi.org/10.1186/S12906-015-0788-Z/FIGURES/2

Article  Google Scholar 

Jayatilleke E, Shaw S (1993) A high-performance liquid chromatographic assay for reduced and oxidized glutathione in biological samples. Anal Biochem 214(2):452–457

Article  CAS  PubMed  Google Scholar 

Jin Y, Sun LH, Yang W, Cui RJ, Xu SB (2019) The role of BDNF in the neuroimmune axis regulation of mood disorders. In Frontiers in Neurology (Vol. 10, Issue JUN, p. 515). Frontiers Media SA. https://doi.org/10.3389/fneur.2019.00515

Karatepe M (2004) Simultaneous determination of ascorbic acid and free Malondialdehyde in Human serum by HPLC-UV. Lc Gc North Am 22(4):362–365

CAS  Google Scholar 

Khalil M, Zhang Z, Engel MA (2019) Neuro-Immune Networks in Gastrointestinal disorders. Visc Med 35(1):52–60. https://doi.org/10.1159/000496838

Article  PubMed  PubMed Central  Google Scholar 

Konsman JP (2022) Cytokines in the Brain and Neuroinflammation: We Didn’t Starve the Fire! Pharmaceuticals (2022) Vol. 15, Page 140, 15(2), 140. https://doi.org/10.3390/PH15020140

Kuwabara T, Ishikawa F, Kondo M, Kakiuchi T (2017) The role of IL-17 and related cytokines in Inflammatory Autoimmune diseases. Mediat Inflamm 2017:3908061. https://doi.org/10.1155/2017/3908061

Article  CAS  Google Scholar 

Li L-J, Gong C, Zhao M-H, Feng B-S (2014) Role of interleukin-22 in inflammatory bowel disease. World J Gastroenterol 20(48):18177–18188. https://doi.org/10.3748/wjg.v20.i48.18177

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lindahl H, Olsson T (2021) Interleukin-22 influences the Th1/Th17 Axis. Front Immunol 12:86. https://doi.org/10.3389/FIMMU.2021.618110/BIBTEX

Article  Google Scholar 

Lücke J, Sabihi M, Zhang T, Bauditz LF, Shiri AM, Schmidt-arras D, Giannou AD (2021) The good and the bad about separation anxiety: roles of IL-22 and IL-22BP in liver pathologies. 591–607

Luiz A, Pontes B, De, Clara R, Januário G, Silva E, Cavalcante JC, Stela M, Oliveira M, De, Antonio C, Toledo B, De, Cavalcante JDS (2010) Serotonin and circadian rhythms. 217–228. https://doi.org/10.3922/j.psns.2010.2.011

Mar JS, Ota N, Pokorzynski ND, Peng Y, Jaochico A, Sangaraju D, Skippington E, Lekkerkerker AN, Rothenberg ME, Tan MW, Yi T, Keir ME, Microbiome (2023) 11(1), 1–17. https://doi.org/10.1186/s40168-023-01486-1

Mateos SS, Sánchez CL, Paredes SD, Barriga C, Rodríguez AB (2009) Circadian levels of serotonin in plasma and brain after oral administration of Tryptophan in rats. Basic Clin Pharmacol Toxicol 104(1):5259. https://doi.org/10.1111/J.1742.7843.2008.00333.X

Article  Google Scholar 

Mattson KM and M P (2015) NIH Public Access 25(2):89–98. https://doi.org/10.1016/j.tem.2013.10.006

Article  CAS  Google Scholar 

McKinley S, Willoughby DS (2014) Effectiveness of antioxidant nutraceuticals in attenuating canonical NF-κb signaling in human skeletal muscle resulting from exercise-induced inflammation and oxidative stress. J Nutritional Health Food Eng 1. https://doi.org/10.15406/JNHFE.2014.01.00033

Merritt AJ, Potten CS, Watson AJM, Loh DY, Nakayama -I K, Nakayama K, Hickman JA (1995) Differential expression of bcl-2 in intestinal epithelia. Correlation with attenuation of apoptosis in colonic crypts and the incidence of colonic neoplasia. J Cell Sci 108(6):2261–2271

Article  CAS  PubMed  Google Scholar 

Mittal R, Debs LH, Patel AP, Nguyen D, Patel K, O’Connor G, Grati M, Mittal J, Yan D, Eshraghi AA, Deo S, Daunert K S, Liu XZ (2017a) Neurotransmitters: the critical modulators regulating gut-brain Axis. J Cell Physiol 232(9):2359–2372. https://doi.org/10.1002/jcp.25518

Article  CAS  PubMed  PubMed Central  Google Scholar 

Mittal R, Debs LH, Patel AP, Nguyen D, Patel K, O’Connor G, Grati M, Mittal J, Yan D, Eshraghi AA, Deo S, Daunert K S, Liu XZ (2017b) Neurotransmitters: the critical modulators regulating gut-brain Axis. J Cell Physiol 232(9):2359–2372. https://doi.org/10.1002/jcp.25518

Article  CAS  PubMed  PubMed Central  Google Scholar 

Mühl H, Scheiermann P, Bachmann M, Härdle L, Heinrichs A, Pfeilschifter J (2013) IL-22 in tissue-protective therapy. Br J Pharmacol 169(4):761–771. https://doi.org/10.1111/bph.12196

Article  CAS  PubMed  PubMed Central  Google Scholar 

Pagel P, Blome J, Wolf HU (2000) High-performance liquid chromatographic separation and measurement of various biogenic compounds possibly involved in the pathomechanism of Parkinson’s disease. J Chromatography:BiomedicalSciencesandApplications 746(2). https://doi.org/10.1016/S03784347(00)00348-0